Lista de obras - Nicolas Grégoire - Dominio Público Uruguay

A Population WB-PBPK Model of Colistin and its Prodrug CMS in Pigs: Focus on the Renal Distribution and Excretion

artículo científico publicado en 2018

A Whole-Body Physiologically Based Pharmacokinetic Model for Colistin and Colistin methanesulfonate (CMS) in Rat.

artículo científico publicado en 2018

A preclinical pharmacokinetic modeling approach to the biopharmaceutical characterization of immediate and microsphere-based sustained release pulmonary formulations of rifampicin.

artículo científico publicado en 2012

Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats. 4. Aztreonam.

artículo científico publicado en 2016

Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 3. Tobramycin.

artículo científico publicado en 2015

Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 6. Aminoglycosides

artículo científico publicado en 2018

Biopharmaceutical characterization of nebulized antimicrobial agents in rats: 1. Ciprofloxacin, moxifloxacin, and grepafloxacin.

artículo científico publicado en 2014

Biopharmaceutical characterization of nebulized antimicrobial agents in rats: 2. Colistin

artículo científico publicado en 2014

Clinical Pharmacokinetics and Pharmacodynamics of Colistin.

artículo científico publicado en 2017

Colistin Pharmacokinetics in Pediatrics

artículo científico publicado en 2017

Colistin distribution in the peritoneal fluid of a patient with severe peritonitis.

artículo científico publicado en 2012

Colistin in critically ill patients

artículo científico publicado el 17 de diciembre de 2012

Colistin pharmacokinetics: the fog is lifting

artículo científico publicado en 2011

Comparison of intrapulmonary and systemic pharmacokinetics of colistin methanesulfonate (CMS) and colistin after aerosol delivery and intravenous administration of CMS in critically ill patients.

artículo científico publicado en 2014

Convulsions and apnoea in a patient infected with New Delhi metallo-β-lactamase-1 Escherichia coli treated with colistin.

artículo científico publicado en 2011

Distinguishing Antimicrobial Models with Different Resistance Mechanisms via Population Pharmacodynamic Modeling

artículo científico publicado en 2016

Lack of effect of extracorporeal membrane oxygenation on tigecycline pharmacokinetics

artículo científico publicado en 2011

Lack of experimental evidence to support mcr-1-positive Escherichia coli strain selection during oral administration of colistin at recommended and higher dose given by gavage in weaned piglets.

artículo científico publicado en 2017

Microdialysis study of cefotaxime cerebral distribution in patients with acute brain injury.

artículo científico publicado en 2013

Modeling Approach To Characterize Intraocular Doripenem Pharmacokinetics after Intravenous Administration to Rabbits, with Tentative Extrapolation to Humans ⬇️

artículo científico publicado el 23 de abril de 2012

Nefopam pharmacokinetics in patients with end-stage renal disease.

artículo científico publicado en 2010

New colistin population pharmacokinetic data in critically ill patients suggesting an alternative loading dose rationale.

artículo científico publicado en 2014

Pharmacodynamic modelling of β-lactam/β-lactamase inhibitor checkerboard data: illustration with aztreonam-avibactam

artículo científico publicado en 2018

Pharmacokinetics of Colistin Methansulphonate (CMS) and Colistin after CMS Nebulisation in Baboon Monkeys

artículo científico publicado en 2015

Pharmacokinetics of Colistin and Colistimethate Sodium After a Single 80-mg Intravenous Dose of CMS in Young Healthy Volunteers

artículo científico publicado el 4 de mayo de 2011

Pharmacokinetics of Polymyxins in Animals

artículo científico publicado en 2019

Pharmacokinetics of colistin after nebulization or intravenous administration of colistin methanesulphonate (Colimycin®) to cystic fibrosis patients

scientific article published on 06 September 2019

Pharmacokinetics of colistin in a 8-year-old child with acute bone infection

scientific article published on 30 April 2018

Pharmacokinetics of intravenous and nebulized gentamicin in critically ill patients

artículo científico publicado en 2018

Pharmacokinetics of nebulized colistin methanesulfonate in critically ill patients

artículo científico publicado en 2017

Pharmacokinetics of tedizolid in obese patient after bariatric surgery: a case report

artículo científico publicado en 2018

Population Pharmacokinetics of Amitriptyline After Intrathecal, Epidural, and Intravenous Administration in Sheep

artículo científico publicado en 2015

Population Pharmacokinetics of Colistin Methanesulfonate and Colistin in Critically Ill Patients with Acute Renal Failure Requiring Intermittent Hemodialysis.

artículo científico publicado en 2016

Population pharmacokinetic analysis of Ibuprofen enantiomers in preterm newborn infants.

artículo científico publicado en 2008

Population pharmacokinetics of daptomycin in critically ill patients with various degrees of renal impairment

artículo científico publicado en 2019

Population pharmacokinetics of ibuprofen enantiomers in very premature neonates.

artículo científico publicado en 2004

Preclinical Pharmacokinetic and Pharmacodynamic Data To Support Cefoxitin Nebulization for the Treatment of Mycobacterium abscessus

scientific article published on 24 June 2019

Pulmonary delivery of pyrazinamide-loaded large porous particles.

artículo científico publicado en 2015

Pulmonary pharmacokinetics of levofloxacin in rats after aerosolization of immediate-release chitosan or sustained-release PLGA microspheres

artículo científico publicado en 2016

Reassessing the dosing of cefoxitin prophylaxis during major abdominal surgery: insights from microdialysis and population pharmacokinetic modelling

artículo científico publicado en 2019

Safety and pharmacokinetics of paracetamol following intravenous administration of 5 g during the first 24 h with a 2-g starting dose

scientific article published on 01 March 2007

Semi-mechanistic PK/PD modelling of combined polymyxin B and minocycline against a polymyxin-resistant strain of Acinetobacter baumannii

artículo científico publicado en 2020

Semimechanistic Pharmacodynamic Modeling of Aztreonam-Avibactam Combination to Understand Its Antimicrobial Activity Against Multidrug-Resistant Gram-Negative Bacteria

artículo científico publicado en 2019

The inoculum effect of Escherichia coli expressing mcr-1 or not on colistin activity in a murine model of peritonitis

artículo científico publicado en 2019

[Anticancer drugs pharmacokinetics update]

scientific article published on 01 January 1999

Lista de obras de Nicolas Grégoire

A Population WB-PBPK Model of Colistin and its Prodrug CMS in Pigs: Focus on the Renal Distribution and Excretion

A Whole-Body Physiologically Based Pharmacokinetic Model for Colistin and Colistin methanesulfonate (CMS) in Rat.

A preclinical pharmacokinetic modeling approach to the biopharmaceutical characterization of immediate and microsphere-based sustained release pulmonary formulations of rifampicin.

Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats. 4. Aztreonam.

Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 3. Tobramycin.

Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 6. Aminoglycosides

Biopharmaceutical characterization of nebulized antimicrobial agents in rats: 1. Ciprofloxacin, moxifloxacin, and grepafloxacin.

Biopharmaceutical characterization of nebulized antimicrobial agents in rats: 2. Colistin

Clinical Pharmacokinetics and Pharmacodynamics of Colistin.

Colistin Pharmacokinetics in Pediatrics

Colistin distribution in the peritoneal fluid of a patient with severe peritonitis.

Colistin in critically ill patients

Colistin pharmacokinetics: the fog is lifting

Comparison of intrapulmonary and systemic pharmacokinetics of colistin methanesulfonate (CMS) and colistin after aerosol delivery and intravenous administration of CMS in critically ill patients.

Convulsions and apnoea in a patient infected with New Delhi metallo-β-lactamase-1 Escherichia coli treated with colistin.

Distinguishing Antimicrobial Models with Different Resistance Mechanisms via Population Pharmacodynamic Modeling

Lack of effect of extracorporeal membrane oxygenation on tigecycline pharmacokinetics

Lack of experimental evidence to support mcr-1-positive Escherichia coli strain selection during oral administration of colistin at recommended and higher dose given by gavage in weaned piglets.

Microdialysis study of cefotaxime cerebral distribution in patients with acute brain injury.

Modeling Approach To Characterize Intraocular Doripenem Pharmacokinetics after Intravenous Administration to Rabbits, with Tentative Extrapolation to Humans ⬇️

Nefopam pharmacokinetics in patients with end-stage renal disease.

New colistin population pharmacokinetic data in critically ill patients suggesting an alternative loading dose rationale.

Pharmacodynamic modelling of β-lactam/β-lactamase inhibitor checkerboard data: illustration with aztreonam-avibactam

Pharmacokinetics of Colistin Methansulphonate (CMS) and Colistin after CMS Nebulisation in Baboon Monkeys

Pharmacokinetics of Colistin and Colistimethate Sodium After a Single 80-mg Intravenous Dose of CMS in Young Healthy Volunteers

Pharmacokinetics of Polymyxins in Animals

Pharmacokinetics of colistin after nebulization or intravenous administration of colistin methanesulphonate (Colimycin®) to cystic fibrosis patients

Pharmacokinetics of colistin in a 8-year-old child with acute bone infection

Pharmacokinetics of intravenous and nebulized gentamicin in critically ill patients

Pharmacokinetics of nebulized colistin methanesulfonate in critically ill patients

Pharmacokinetics of tedizolid in obese patient after bariatric surgery: a case report

Population Pharmacokinetics of Amitriptyline After Intrathecal, Epidural, and Intravenous Administration in Sheep

Population Pharmacokinetics of Colistin Methanesulfonate and Colistin in Critically Ill Patients with Acute Renal Failure Requiring Intermittent Hemodialysis.

Population pharmacokinetic analysis of Ibuprofen enantiomers in preterm newborn infants.

Population pharmacokinetics of daptomycin in critically ill patients with various degrees of renal impairment

Population pharmacokinetics of ibuprofen enantiomers in very premature neonates.

Preclinical Pharmacokinetic and Pharmacodynamic Data To Support Cefoxitin Nebulization for the Treatment of Mycobacterium abscessus

Pulmonary delivery of pyrazinamide-loaded large porous particles.

Pulmonary pharmacokinetics of levofloxacin in rats after aerosolization of immediate-release chitosan or sustained-release PLGA microspheres

Reassessing the dosing of cefoxitin prophylaxis during major abdominal surgery: insights from microdialysis and population pharmacokinetic modelling

Safety and pharmacokinetics of paracetamol following intravenous administration of 5 g during the first 24 h with a 2-g starting dose

Semi-mechanistic PK/PD modelling of combined polymyxin B and minocycline against a polymyxin-resistant strain of Acinetobacter baumannii

Semimechanistic Pharmacodynamic Modeling of Aztreonam-Avibactam Combination to Understand Its Antimicrobial Activity Against Multidrug-Resistant Gram-Negative Bacteria

The inoculum effect of Escherichia coli expressing mcr-1 or not on colistin activity in a murine model of peritonitis

[Anticancer drugs pharmacokinetics update]