Lista de obras - Erik B van den Akker - Dominio Público Uruguay

A genome-wide association study identifies a region at chromosome 12 as a potential susceptibility locus for restenosis after percutaneous coronary intervention

artículo científico publicado en 2011

A genome-wide association study identifies genetic loci associated with specific lobar brain volumes

scientific article published on 02 August 2019

A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

scientific article published on 20 August 2019

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

article by Sven J. van der Lee et al published 27 May 2019 in Acta Neuropathologica

A transcriptomic based deconvolution framework for assessing differentiation stages and drug responses of AML

artículo científico publicado en 2024

Aging as accelerated accumulation of somatic variants: whole-genome sequencing of centenarian and middle-aged monozygotic twin pairs

artículo científico publicado en 2013

Association of common genetic variants with brain microbleeds: A Genome-wide Association Study

scientific article published on 10 September 2020

Broad phenotype of cysteine altering NOTCH3 variants in UK Biobank: CADASIL to non-penetrance

scientific article published on 30 July 2020

Cerebral small vessel disease genomics and its implications across the lifespan

artículo científico publicado en 2020

Comprehensive diagnostics of acute myeloid leukemia by whole transcriptome RNA sequencing

artículo científico publicado en 2020

Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

scientific article published on 18 January 2020

Correction: Transcriptional Profiling of Human Familial Longevity Indicates a Role for ASF1A and IL7R.

artículo científico publicado en 2012

Dynamic clonal hematopoiesis and functional T-cell immunity in a supercentenarian

artículo científico publicado en 2020

Employing biomarkers of healthy ageing for leveraging genetic studies into human longevity

artículo científico publicado en 2016

Exome and whole genome sequencing in aging and longevity.

artículo científico

Fibroblast growth factor 21 reflects liver fat accumulation and dysregulation of signalling pathways in the liver of C57BL/6J mice.

artículo científico publicado en 2016

Gene analysis for longitudinal family data using random-effects models

artículo científico publicado en 2014

Gene coexpression network analysis for family studies based on a meta-analytic approach

artículo científico publicado en 2016

Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways

artículo científico publicado en 2011

Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns

artículo científico publicado en 2018

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

artículo científico publicado en 2014

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited

artículo científico publicado en 2011

Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

artículo científico publicado en 2013

High-throughput data-driven analysis of myofiber composition reveals muscle-specific disease and age-associated patterns

artículo científico publicado en 2018

Human Plasma N-glycosylation as Analyzed by Matrix-Assisted Laser Desorption/Ionization-Fourier Transform Ion Cyclotron Resonance-MS Associates with Markers of Inflammation and Metabolic Health ⬇️

artículo científico publicado en 2016

IL7R gene expression network associates with human healthy ageing

artículo científico publicado en 2015

Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array

artículo científico publicado en 2013

IgG glycosylation and DNA methylation are interconnected with smoking

artículo científico publicado en 2017

Integrating protein-protein interaction networks with gene-gene co-expression networks improves gene signatures for classifying breast cancer metastasis

artículo científico publicado en 2011

Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas

scientific article published on 13 January 2020

Machine Learning Electronic Health Record Identification of Patients with Rheumatoid Arthritis: Algorithm Pipeline Development and Validation Study

scientific article published on 30 November 2020

Meta-analysis on blood transcriptomic studies identifies consistently coexpressed protein-protein interaction modules as robust markers of human aging

artículo científico publicado en 2013

Metabolic Age Based on the BBMRI-NL 1H-NMR Metabolomics Repository as Biomarker of Age-related Disease

artículo científico publicado en 2020

Metabolic effects of a 13-weeks lifestyle intervention in older adults: The Growing Old Together Study

artículo científico publicado en 2016

Pan-cancer subtyping in a 2D-map shows substructures that are driven by specific combinations of molecular characteristics

artículo científico publicado en 2016

Patients with Concurrent Tuberculosis and Diabetes Have a Pro-Atherogenic Plasma Lipid Profile.

artículo científico publicado en 2018

The effect of standardized food intake on the association between BMI and 1H-NMR metabolites.

artículo científico publicado en 2016

Transcriptional profiling of human familial longevity indicates a role for ASF1A and IL7R

artículo científico publicado en 2012

Uncompromised 10-year survival of oldest old carrying somatic mutations in DNMT3A and TET2.

artículo científico publicado en 2016

Underlying molecular mechanisms of DIO2 susceptibility in symptomatic osteoarthritis

artículo científico publicado en 2014

Lista de obras de Erik B van den Akker

A genome-wide association study identifies a region at chromosome 12 as a potential susceptibility locus for restenosis after percutaneous coronary intervention

A genome-wide association study identifies genetic loci associated with specific lobar brain volumes

A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

A transcriptomic based deconvolution framework for assessing differentiation stages and drug responses of AML

Aging as accelerated accumulation of somatic variants: whole-genome sequencing of centenarian and middle-aged monozygotic twin pairs

Association of common genetic variants with brain microbleeds: A Genome-wide Association Study

Broad phenotype of cysteine altering NOTCH3 variants in UK Biobank: CADASIL to non-penetrance

Cerebral small vessel disease genomics and its implications across the lifespan

Comprehensive diagnostics of acute myeloid leukemia by whole transcriptome RNA sequencing

Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

Correction: Transcriptional Profiling of Human Familial Longevity Indicates a Role for ASF1A and IL7R.

Dynamic clonal hematopoiesis and functional T-cell immunity in a supercentenarian

Employing biomarkers of healthy ageing for leveraging genetic studies into human longevity

Exome and whole genome sequencing in aging and longevity.

Fibroblast growth factor 21 reflects liver fat accumulation and dysregulation of signalling pathways in the liver of C57BL/6J mice.

Gene analysis for longitudinal family data using random-effects models

Gene coexpression network analysis for family studies based on a meta-analytic approach

Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways

Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited

Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

High-throughput data-driven analysis of myofiber composition reveals muscle-specific disease and age-associated patterns

Human Plasma N-glycosylation as Analyzed by Matrix-Assisted Laser Desorption/Ionization-Fourier Transform Ion Cyclotron Resonance-MS Associates with Markers of Inflammation and Metabolic Health ⬇️

IL7R gene expression network associates with human healthy ageing

Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array

IgG glycosylation and DNA methylation are interconnected with smoking

Integrating protein-protein interaction networks with gene-gene co-expression networks improves gene signatures for classifying breast cancer metastasis

Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas

Machine Learning Electronic Health Record Identification of Patients with Rheumatoid Arthritis: Algorithm Pipeline Development and Validation Study

Meta-analysis on blood transcriptomic studies identifies consistently coexpressed protein-protein interaction modules as robust markers of human aging

Metabolic Age Based on the BBMRI-NL 1H-NMR Metabolomics Repository as Biomarker of Age-related Disease

Metabolic effects of a 13-weeks lifestyle intervention in older adults: The Growing Old Together Study

Pan-cancer subtyping in a 2D-map shows substructures that are driven by specific combinations of molecular characteristics

Patients with Concurrent Tuberculosis and Diabetes Have a Pro-Atherogenic Plasma Lipid Profile.

The effect of standardized food intake on the association between BMI and 1H-NMR metabolites.

Transcriptional profiling of human familial longevity indicates a role for ASF1A and IL7R

Uncompromised 10-year survival of oldest old carrying somatic mutations in DNMT3A and TET2.

Underlying molecular mechanisms of DIO2 susceptibility in symptomatic osteoarthritis