Lista de obras - Elias Arnér - Dominio Público Uruguay

(In)Visible Dialogues

art project

1-Chloro-2,4-dinitrobenzene is an irreversible inhibitor of human thioredoxin reductase. Loss of thioredoxin disulfide reductase activity is accompanied by a large increase in NADPH oxidase activity

artículo científico publicado en 1995

A novel persulfide detection method reveals protein persulfide- and polysulfide-reducing functions of thioredoxin and glutathione systems.

artículo científico publicado en 2016

APR-246/PRIMA-1MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase

artículo científico publicado en 2013

APR-246/PRIMA-1MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase.

artículo científico publicado en 2017

Absence of TXNIP in Humans Leads to Lactic Acidosis and Low Serum Methionine Linked to Deficient Respiration on Pyruvate

scientific article published on 12 February 2019

Active sites of thioredoxin reductases: why selenoproteins?

artículo científico publicado en 2003

Assessment of production conditions for efficient use of Escherichia coli in high-yield heterologous recombinant selenoprotein synthesis.

artículo científico publicado en 2004

Author Correction: Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system

artículo científico publicado en 2019

Bicarbonate is essential for protein-tyrosine phosphatase 1B (PTP1B) oxidation and cellular signaling through EGF-triggered phosphorylation cascades

scientific article published on 13 June 2019

Catabolism of deoxycytidine in human peripheral blood mononuclear cells and its interference with the determination of in situ thymidylate synthase activity

scientific article published on 01 April 1993

Characterization of Lead Compounds Targeting the Selenoprotein Thioredoxin Glutathione Reductase for Treatment of Schistosomiasis

artículo científico publicado en 2020

Chemical Reactivity Window Determines Prodrug Efficiency toward Glutathione Transferase Overexpressing Cancer Cells

artículo científico publicado en 2016

Cisplatin and oxaliplatin are toxic to cochlear outer hair cells and both target thioredoxin reductase in organ of Corti cultures

artículo científico publicado en 2014

Common modifications of selenocysteine in selenoproteins

artículo científico publicado en 2020

Comprehensive chemical proteomics analyses reveal that the new TRi-1 and TRi-2 compounds are more specific thioredoxin reductase 1 inhibitors than auranofin

artículo científico publicado en 2021

Control of protein function through oxidation and reduction of persulfidated states

scientific article published on 01 January 2020

Cross Talk in HEK293 Cells Between Nrf2, HIF, and NF-κB Activities upon Challenges with Redox Therapeutics Characterized with Single-Cell Resolution.

artículo científico publicado en 2015

Crystal structure and catalysis of the selenoprotein thioredoxin reductase 1

artículo científico publicado en 2009

Cytosolic thioredoxin reductase 1 is required for correct disulfide formation in the ER.

artículo científico publicado en 2017

Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system

scientific article published on 08 July 2019

Deoxycytidine and 2',3'-dideoxycytidine metabolism in human monocyte-derived macrophages. A study of both anabolic and catabolic pathways.

artículo científico publicado en 1993

Details in the catalytic mechanism of mammalian thioredoxin reductase 1 revealed using point mutations and juglone-coupled enzyme activities

artículo científico publicado en 2016

Dietary methionine can sustain cytosolic redox homeostasis in the mouse liver.

artículo científico publicado en 2015

Differential regulation of expression of cytosolic and mitochondrial thioredoxin reductase in rat liver and kidney

scientific article published on 22 January 2007

Direct Observation of Methylmercury and Auranofin Binding to Selenocysteine in Thioredoxin Reductase

artículo científico publicado en 2020

Effects of selenite and chelating agents on mammalian thioredoxin reductase inhibited by mercury: implications for treatment of mercury poisoning

scientific journal article

Efficient selenocysteine-dependent reduction of toxoflavin by mammalian thioredoxin reductase

scientific article published on 25 May 2018

Entinostat up-regulates the CAMP gene encoding LL-37 via activation of STAT3 and HIF-1α transcription factors

artículo científico publicado en 2016

Evidence for intriguingly complex transcription of human thioredoxin reductase 1.

artículo científico publicado en 2004

Expression and substrate specificities of human thymidine kinase 1, thymidine kinase 2 and deoxycytidine kinase

scientific article published on 01 January 1991

Expression of selenocysteine-containing glutathione S-transferase in Escherichia coli.

artículo científico publicado en 2004

Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as “Doorstop” for NADPH Entry

artículo científico publicado en 2018

HER2-positive tumors imaged within 1 hour using a site-specifically 11C-labeled Sel-tagged affibody molecule.

artículo científico publicado en 2012

Hepatocyte DNA replication in growing liver requires either glutathione or a single allele of txnrd1 ⬇️

artículo científico publicado el 8 de diciembre de 2011

Hepatocyte Hyperproliferation upon Liver-Specific Co-disruption of Thioredoxin-1, Thioredoxin Reductase-1, and Glutathione Reductase.

artículo científico publicado en 2017

Highly active dimeric and low-activity tetrameric forms of selenium-containing rat thioredoxin reductase 1

scientific journal article

Indolin-2-one compounds targeting thioredoxin reductase as potential anticancer drug leads

artículo científico publicado en 2016

Inhibition of thioredoxin reductase but not of glutathione reductase by the major classes of alkylating and platinum-containing anticancer compounds.

artículo científico publicado en 2005

Inhibitory nitrosylation of mammalian thioredoxin reductase 1: Molecular characterization and evidence for its functional role in cellular nitroso-redox imbalance

artículo científico publicado en 2016

Irreversible TrxR1 inhibitors block STAT3 activity and induce cancer cell death

scientific article published on 20 March 2020

Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy.

artículo científico publicado en 2018

Mammalian deoxyribonucleoside kinases

artículo científico publicado en 1995

Mammalian thioredoxin reductase is irreversibly inhibited by dinitrohalobenzenes by alkylation of both the redox active selenocysteine and its neighboring cysteine residue

artículo científico publicado en 1998

Maximal flux responses after multiple challenges with vasopressin

artículo científico publicado en 1984

Measurement of Thioredoxin and Thioredoxin Reductase ⬇️

artículo científico publicado el 1 de mayo de 2001

Mitochondrial peroxiredoxin 3 is rapidly oxidized in cells treated with isothiocyanates.

artículo científico publicado en 2008

Mitochondrial versus cytosolic activities of deoxyribonucleoside salvage enzymes.

artículo científico publicado en 1994

Molecular Basis for the Interactions of Human Thioredoxins with Their Respective Reductases

artículo científico publicado en 2021

Multilevel regulation of 2-Cys peroxiredoxin reaction cycle by S-nitrosylation

artículo científico publicado en 2013

Noble metal targeting of thioredoxin reductase--covalent complexes with thioredoxin and thioredoxin-related protein of 14 kDa triggered by cisplatin.

artículo científico publicado en 2010

On the phosphorylation of 2-chlorodeoxyadenosine (CdA) and its correlation with clinical response in leukemia treatment.

artículo científico publicado en 1996

Overexpression of Recombinant Selenoproteins in E. coli

artículo científico publicado en 2018

Overexpression of enzymatically active human cytosolic and mitochondrial thioredoxin reductase in HEK-293 cells. Effect on cell growth and differentiation.

artículo científico publicado en 2004

Phosphorylation of 2-chlorodeoxyadenosine (CdA) in extracts of peripheral blood mononuclear cells of leukaemic patients

scientific article published on 01 August 1994

Physiological functions of thioredoxin and thioredoxin reductase

artículo científico publicado en 2000

Preclinical PET imaging of EGFR levels: pairing a targeting with a non-targeting Sel-tagged Affibody-based tracer to estimate the specific uptake.

artículo científico publicado en 2016

Preparation and assay of mammalian thioredoxin and thioredoxin reductase

artículo científico publicado en 1999

Prolonged antigen-exposure with carbohydrate particle based vaccination prevents allergic immune responses in sensitized mice.

artículo científico publicado en 2009

Properties and levels of deoxynucleoside kinases in normal and tumor cells; implications for chemotherapy

artículo científico publicado en 1994

Pyrroloquinoline quinone modulates the kinetic parameters of the mammalian selenoprotein thioredoxin reductase 1 and is an inhibitor of glutathione reductase ⬇️

artículo científico publicado el 29 de diciembre de 2011

ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis.

scientific article published on 10 January 2014

Rapid induction of cell death by selenium-compromised thioredoxin reductase 1 but not by the fully active enzyme containing selenocysteine

scientific journal article

Rat and calf thioredoxin reductase are homologous to glutathione reductase with a carboxyl-terminal elongation containing a conserved catalytically active penultimate selenocysteine residue.

artículo científico publicado en 1998

Redox Pioneer: Professor Arne Holmgren ⬇️

artículo científico publicado el 6 de junio de 2011

Redox active motifs in selenoproteins

artículo científico publicado en 2014

Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells.

artículo científico publicado en 2015

Regeneration of the antioxidant ubiquinol by lipoamide dehydrogenase, thioredoxin reductase and glutathione reductase.

artículo científico publicado en 2003

Regulation of the mammalian selenoprotein thioredoxin reductase 1 in relation to cellular phenotype, growth, and signaling events.

artículo científico publicado en 2004

Rutin protects against H2O2-triggered impaired relaxation of placental arterioles and induces Nrf2-mediated adaptation in Human Umbilical Vein Endothelial Cells exposed to oxidative stress

artículo científico publicado en 2017

Sec-containing TrxR1 is essential for self-sufficiency of cells by control of glucose-derived H2O2.

artículo científico publicado en 2014

Selective Evaluation of Thioredoxin Reductase Enzymatic Activities

artículo científico publicado en 2018

Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-β receptor tyrosine kinase signaling.

artículo científico publicado en 2013

Selective assays for thymidine kinase 1 and 2 and deoxycytidine kinase and their activities in extracts from human cells and tissues.

artículo científico publicado en 1992

Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis.

artículo científico publicado en 2017

Selenium and selenoproteins in (redox) signaling, diseases, and animal models - 200 year anniversary issue

scientific article published on 01 November 2018

Selenium research in biochemistry and biophysics - 200 year anniversary issue

artículo científico publicado en 2018

Selenocysteine Insertion at a Predefined UAG Codon in a Release Factor 1 (RF1)-depleted Escherichia coli Host Strain Bypasses Species Barriers in Recombinant Selenoprotein Translation

artículo científico publicado en 2017

Selenolthiol and dithiol C-terminal tetrapeptide motifs for one-step purification and labeling of recombinant proteins produced in E. coli.

artículo científico publicado en 2006

Selenoprotein Gene Nomenclature

artículo científico publicado en 2016

Selenoprotein TRXR-1 and GSR-1 are essential for removal of old cuticle during molting in Caenorhabditis elegans

artículo científico publicado en 2011

Selenoproteins-What unique properties can arise with selenocysteine in place of cysteine?

artículo científico publicado en 2010

Sepp1(UF) forms are N-terminal selenoprotein P truncations that have peroxidase activity when coupled with thioredoxin reductase-1

artículo científico publicado en 2014

Serum thioredoxin reductase is highly increased in mice with hepatocellular carcinoma and its activity is restrained by several mechanisms.

artículo científico publicado en 2016

Serum thioredoxin reductase levels increase in response to chemically induced acute liver injury

artículo científico publicado en 2014

Simvastatin inhibits the core promoter of the TXNRD1 gene and lowers cellular TrxR activity in HepG2 cells.

artículo científico publicado en 2012

Site-specifically 11C-labeled Sel-tagged annexin A5 and a size-matched control for dynamic in vivo PET imaging of protein distribution in tissues prior to and after induced cell death.

artículo científico publicado en 2013

Special issue on selenoprotein expression and function

artículo científico publicado en 2009

Studies of an active site mutant of the selenoprotein thioredoxin reductase: the Ser-Cys-Cys-Ser motif of the insect orthologue is not sufficient to replace the Cys-Sec dyad in the mammalian enzyme.

artículo científico publicado en 2006

Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: Implications for development of specific inhibitors.

artículo científico publicado en 2010

Substrate specificity of mitochondrial 2'-deoxyguanosine kinase. Efficient phosphorylation of 2-chlorodeoxyadenosine

artículo científico publicado en 1993

Superoxide production by dinitrophenyl-derivatized thioredoxin reductase--a model for the mechanism and correlation to immunostimulation by dinitrohalobenzenes

artículo científico publicado en 1999

System-wide identification and prioritization of enzyme substrates by thermal analysis

artículo científico publicado en 2021

Tagging recombinant proteins with a Sel-tag for purification, labeling with electrophilic compounds or radiolabeling with 11C.

artículo científico publicado en 2006

The 19S Deubiquitinase inhibitor b-AP15 is enriched in cells and elicits rapid commitment to cell death.

artículo científico publicado en 2014

The A to Z of modulated cell patterning by mammalian thioredoxin reductases.

artículo científico publicado en 2017

The conserved Trp114 residue of thioredoxin reductase 1 has a redox sensor-like function triggering oligomerization and crosslinking upon oxidative stress related to cell death

artículo científico publicado en 2015

The core promoter of human thioredoxin reductase 1: cloning, transcriptional activity, and Oct-1, Sp1, and Sp3 binding reveal a housekeeping-type promoter for the AU-rich element-regulated gene.

artículo científico

The rare TXNRD1_v3 ("v3") splice variant of human thioredoxin reductase 1 protein is targeted to membrane rafts by N-acylation and induces filopodia independently of its redox active site integrity.

artículo científico publicado en 2013

The thioredoxin system in cancer-introduction to a thematic volume of Seminars in Cancer Biology

artículo científico publicado en 2006

Thiophosphate and selenite conversely modulate cell death induced by glutathione depletion or cisplatin: effects related to activity and Sec contents of thioredoxin reductase.

artículo científico publicado en 2012

Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target

artículo científico publicado en 2007

Thioredoxin reductase 1 and NADPH directly protect protein tyrosine phosphatase 1B from inactivation during H2O2 exposure

artículo científico publicado en 2017

Thioredoxin reductase 1 suppresses adipocyte differentiation and insulin responsiveness

artículo científico publicado en 2016

Thioredoxin-related protein of 14 kDa is an efficient L-cystine reductase and S-denitrosylase.

artículo científico publicado en 2014

Thioredoxin-related protein of 14 kDa as a modulator of redox signalling pathways

scientific article published on 06 October 2018

Thymidine and 3'-azido-3'-deoxythymidine metabolism in human peripheral blood lymphocytes and monocyte-derived macrophages. A study of both anabolic and catabolic pathways ⬇️

artículo científico publicado el 5 de junio de 1992

Time- and cell-resolved dynamics of redox-sensitive Nrf2, HIF and NF-κB activities in 3D spheroids enriched for cancer stem cells.

artículo científico publicado en 2017

Titration and conditional knockdown of the prfB gene in Escherichia coli: effects on growth and overproduction of the recombinant mammalian selenoprotein thioredoxin reductase.

artículo científico publicado en 2006

Truncated thioredoxin is a mitogenic cytokine for resting human peripheral blood mononuclear cells and is present in human plasma

scientific article published on 01 December 2000

TrxR1 as a potent regulator of the Nrf2-Keap1 response system

artículo científico publicado en 2015

TrxR1, Gsr, and oxidative stress determine hepatocellular carcinoma malignancy

scientific article published on 16 May 2019

Wobble decoding by the Escherichia coli selenocysteine insertion machinery.

artículo científico publicado en 2013

Lista de obras de Elias Arnér

(In)Visible Dialogues

1-Chloro-2,4-dinitrobenzene is an irreversible inhibitor of human thioredoxin reductase. Loss of thioredoxin disulfide reductase activity is accompanied by a large increase in NADPH oxidase activity

A novel persulfide detection method reveals protein persulfide- and polysulfide-reducing functions of thioredoxin and glutathione systems.

APR-246/PRIMA-1MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase

APR-246/PRIMA-1MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase.

Absence of TXNIP in Humans Leads to Lactic Acidosis and Low Serum Methionine Linked to Deficient Respiration on Pyruvate

Active sites of thioredoxin reductases: why selenoproteins?

Assessment of production conditions for efficient use of Escherichia coli in high-yield heterologous recombinant selenoprotein synthesis.

Author Correction: Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system

Bicarbonate is essential for protein-tyrosine phosphatase 1B (PTP1B) oxidation and cellular signaling through EGF-triggered phosphorylation cascades

Catabolism of deoxycytidine in human peripheral blood mononuclear cells and its interference with the determination of in situ thymidylate synthase activity

Characterization of Lead Compounds Targeting the Selenoprotein Thioredoxin Glutathione Reductase for Treatment of Schistosomiasis

Chemical Reactivity Window Determines Prodrug Efficiency toward Glutathione Transferase Overexpressing Cancer Cells

Cisplatin and oxaliplatin are toxic to cochlear outer hair cells and both target thioredoxin reductase in organ of Corti cultures

Common modifications of selenocysteine in selenoproteins

Comprehensive chemical proteomics analyses reveal that the new TRi-1 and TRi-2 compounds are more specific thioredoxin reductase 1 inhibitors than auranofin

Control of protein function through oxidation and reduction of persulfidated states

Cross Talk in HEK293 Cells Between Nrf2, HIF, and NF-κB Activities upon Challenges with Redox Therapeutics Characterized with Single-Cell Resolution.

Crystal structure and catalysis of the selenoprotein thioredoxin reductase 1

Cytosolic thioredoxin reductase 1 is required for correct disulfide formation in the ER.

Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system

Deoxycytidine and 2',3'-dideoxycytidine metabolism in human monocyte-derived macrophages. A study of both anabolic and catabolic pathways.

Details in the catalytic mechanism of mammalian thioredoxin reductase 1 revealed using point mutations and juglone-coupled enzyme activities

Dietary methionine can sustain cytosolic redox homeostasis in the mouse liver.

Differential regulation of expression of cytosolic and mitochondrial thioredoxin reductase in rat liver and kidney

Direct Observation of Methylmercury and Auranofin Binding to Selenocysteine in Thioredoxin Reductase

Effects of selenite and chelating agents on mammalian thioredoxin reductase inhibited by mercury: implications for treatment of mercury poisoning

Efficient selenocysteine-dependent reduction of toxoflavin by mammalian thioredoxin reductase

Entinostat up-regulates the CAMP gene encoding LL-37 via activation of STAT3 and HIF-1α transcription factors

Evidence for intriguingly complex transcription of human thioredoxin reductase 1.

Expression and substrate specificities of human thymidine kinase 1, thymidine kinase 2 and deoxycytidine kinase

Expression of selenocysteine-containing glutathione S-transferase in Escherichia coli.

Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as “Doorstop” for NADPH Entry

HER2-positive tumors imaged within 1 hour using a site-specifically 11C-labeled Sel-tagged affibody molecule.

Hepatocyte DNA replication in growing liver requires either glutathione or a single allele of txnrd1 ⬇️

Hepatocyte Hyperproliferation upon Liver-Specific Co-disruption of Thioredoxin-1, Thioredoxin Reductase-1, and Glutathione Reductase.

Highly active dimeric and low-activity tetrameric forms of selenium-containing rat thioredoxin reductase 1

Indolin-2-one compounds targeting thioredoxin reductase as potential anticancer drug leads

Inhibition of thioredoxin reductase but not of glutathione reductase by the major classes of alkylating and platinum-containing anticancer compounds.

Inhibitory nitrosylation of mammalian thioredoxin reductase 1: Molecular characterization and evidence for its functional role in cellular nitroso-redox imbalance

Irreversible TrxR1 inhibitors block STAT3 activity and induce cancer cell death

Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy.

Mammalian deoxyribonucleoside kinases

Mammalian thioredoxin reductase is irreversibly inhibited by dinitrohalobenzenes by alkylation of both the redox active selenocysteine and its neighboring cysteine residue

Maximal flux responses after multiple challenges with vasopressin

Measurement of Thioredoxin and Thioredoxin Reductase ⬇️

Mitochondrial peroxiredoxin 3 is rapidly oxidized in cells treated with isothiocyanates.

Mitochondrial versus cytosolic activities of deoxyribonucleoside salvage enzymes.

Molecular Basis for the Interactions of Human Thioredoxins with Their Respective Reductases

Multilevel regulation of 2-Cys peroxiredoxin reaction cycle by S-nitrosylation

Noble metal targeting of thioredoxin reductase--covalent complexes with thioredoxin and thioredoxin-related protein of 14 kDa triggered by cisplatin.

On the phosphorylation of 2-chlorodeoxyadenosine (CdA) and its correlation with clinical response in leukemia treatment.

Overexpression of Recombinant Selenoproteins in E. coli

Overexpression of enzymatically active human cytosolic and mitochondrial thioredoxin reductase in HEK-293 cells. Effect on cell growth and differentiation.

Phosphorylation of 2-chlorodeoxyadenosine (CdA) in extracts of peripheral blood mononuclear cells of leukaemic patients

Physiological functions of thioredoxin and thioredoxin reductase

Preclinical PET imaging of EGFR levels: pairing a targeting with a non-targeting Sel-tagged Affibody-based tracer to estimate the specific uptake.

Preparation and assay of mammalian thioredoxin and thioredoxin reductase

Prolonged antigen-exposure with carbohydrate particle based vaccination prevents allergic immune responses in sensitized mice.

Properties and levels of deoxynucleoside kinases in normal and tumor cells; implications for chemotherapy

Pyrroloquinoline quinone modulates the kinetic parameters of the mammalian selenoprotein thioredoxin reductase 1 and is an inhibitor of glutathione reductase ⬇️

ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis.

Rapid induction of cell death by selenium-compromised thioredoxin reductase 1 but not by the fully active enzyme containing selenocysteine

Rat and calf thioredoxin reductase are homologous to glutathione reductase with a carboxyl-terminal elongation containing a conserved catalytically active penultimate selenocysteine residue.

Redox Pioneer: Professor Arne Holmgren ⬇️

Redox active motifs in selenoproteins

Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells.

Regeneration of the antioxidant ubiquinol by lipoamide dehydrogenase, thioredoxin reductase and glutathione reductase.

Regulation of the mammalian selenoprotein thioredoxin reductase 1 in relation to cellular phenotype, growth, and signaling events.

Rutin protects against H2O2-triggered impaired relaxation of placental arterioles and induces Nrf2-mediated adaptation in Human Umbilical Vein Endothelial Cells exposed to oxidative stress

Sec-containing TrxR1 is essential for self-sufficiency of cells by control of glucose-derived H2O2.

Selective Evaluation of Thioredoxin Reductase Enzymatic Activities

Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-β receptor tyrosine kinase signaling.

Selective assays for thymidine kinase 1 and 2 and deoxycytidine kinase and their activities in extracts from human cells and tissues.

Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis.

Selenium and selenoproteins in (redox) signaling, diseases, and animal models - 200 year anniversary issue

Selenium research in biochemistry and biophysics - 200 year anniversary issue

Selenocysteine Insertion at a Predefined UAG Codon in a Release Factor 1 (RF1)-depleted Escherichia coli Host Strain Bypasses Species Barriers in Recombinant Selenoprotein Translation

Selenolthiol and dithiol C-terminal tetrapeptide motifs for one-step purification and labeling of recombinant proteins produced in E. coli.

Selenium research in biochemistry and biophysics - 200 year anniversary issue