Lista de obras - Tim Ebbels - Dominio Público Uruguay

1H NMR-based profiling reveals differential immune-metabolic networks during influenza virus infection in obese mice

artículo científico publicado en 2014

A combination of transcriptomics and metabolomics uncovers enhanced bile acid biosynthesis in HepG2 cells expressing CCAAT/enhancer-binding protein β (C/EBPβ), hepatocyte nuclear factor 4α (HNF4α), and constitutive androstane receptor (CAR).

artículo científico publicado en 2013

A comparison of human serum and plasma metabolites using untargeted 1H NMR spectroscopy and UPLC-MS

artículo científico publicado en 2018

A statistical framework for biomarker discovery in metabolomic time course data ⬇️

artículo científico publicado el 15 de julio de 2011

A statistically rigorous test for the identification of parent-fragment pairs in LC-MS datasets

artículo científico publicado en 2010

Analytic properties of statistical total correlation spectroscopy based information recovery in 1H NMR metabolic data sets

artículo científico publicado en 2009

Analytical reproducibility in (1)H NMR-based metabonomic urinalysis

artículo científico publicado en 2002

Applying 'omics technologies in chemicals risk assessment: Report of an ECETOC workshop.

artículo científico publicado en 2017

Automated Annotation of Untargeted All-Ion Fragmentation LC–MS Metabolomics Data with MetaboAnnotatoR

artículo científico publicado en 2022

Bayesian estimation of the number of protonation sites for urinary metabolites from NMR spectroscopic data.

artículo científico publicado en 2018

COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access

artículo científico publicado en 2015

Characterization of data analysis methods for information recovery from metabolic 1H NMR spectra using artificial complex mixtures

Cluster analysis statistical spectroscopy using nuclear magnetic resonance generated metabolic data sets from perturbed biological systems

artículo científico publicado en 2009

Comparison of Bi- and Tri-Linear PLS Models for Variable Selection in Metabolomic Time-Series Experiments.

artículo científico publicado en 2019

Computational Metabolomics: From Spectra to Knowledge (Dagstuhl Seminar 22181) ⬇️

proceedings

Computational tools and workflows in metabolomics: An international survey highlights the opportunity for harmonisation through Galaxy

artículo científico publicado en 2017

Data standards can boost metabolomics research, and if there is a will, there is a way

artículo científico publicado en 2016

Data-Driven Approach for Metabolite Relationship Recovery in Biological 1H NMR Data Sets Using Iterative Statistical Total Correlation Spectroscopy ⬇️

artículo científico publicado el 16 de febrero de 2011

Design and analysis of metabolomics studies in epidemiologic research: a primer on -omic technologies

artículo científico

Dietary and urinary metabonomic factors possibly accounting for higher blood pressure of black compared with white Americans: results of International Collaborative Study on macro-/micronutrients and blood pressure

artículo científico publicado en 2013

Effect of the histone deacetylase inhibitor trichostatin a on the metabolome of cultured primary hepatocytes

artículo científico publicado en 2010

Embedding standards in metabolomics: the Metabolomics Society data standards task group

Erratum to: COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access

scholarly article published in Metabolomics

Extraction and Integration of Genetic Networks from Short-Profile Omic Data Sets

artículo científico publicado en 2020

Finding Correspondence between Metabolomic Features in Untargeted Liquid Chromatography–Mass Spectrometry Metabolomics Datasets

artículo científico publicado en 2022

Genetic algorithms for simultaneous variable and sample selection in metabonomics

artículo científico publicado en 2008

Geometric trajectory analysis of metabolic responses to toxicity can define treatment specific profiles

artículo científico publicado en 2004

High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues

artículo científico publicado en 2010

Intra- and Interlaboratory Reproducibility of Ultra Performance Liquid Chromatography–Time-of-Flight Mass Spectrometry for Urinary Metabolic Profiling

article

Meeting-in-the-middle using metabolic profiling - a strategy for the identification of intermediate biomarkers in cohort studies

artículo científico publicado en 2010

MetAssimulo:Simulation of Realistic NMR Metabolic Profiles ⬇️

artículo científico publicado el 6 de octubre de 2010

Metabolic Signatures of Gestational Weight Gain and Postpartum Weight Loss in a Lifestyle Intervention Study of Overweight and Obese Women

scientific article published on 04 December 2020

Metabolic phenotyping for discovery of urinary biomarkers of diet, xenobiotics and blood pressure in the INTERMAP Study: an overview.

artículo científico publicado en 2016

Metabolic profiling and population screening of analgesic usage in nuclear magnetic resonance spectroscopy-based large-scale epidemiologic studies

artículo científico publicado en 2009

Metabolic profiling and the metabolome-wide association study: significance level for biomarker identification

artículo científico publicado en 2010

Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts

artículo científico publicado en 2007

Metabolome-wide association study identifies multiple biomarkers that discriminate north and south Chinese populations at differing risks of cardiovascular disease: INTERMAP study

artículo científico publicado en 2010

Metabolomics - the stethoscope for the 21st century

artículo científico publicado en 2020

Metabonomic investigations into the global biochemical sequelae of exposure to the pancreatic toxin 1-cyano-2-hydroxy-3-butene in the rat.

artículo científico publicado en 2009

Modelling short time series in metabolomics: a functional data analysis approach

artículo científico publicado en 2011

Modelling the acid/base (1)H NMR chemical shift limits of metabolites in human urine

artículo científico publicado en 2016

NMR-based metabolic profiling identifies biomarkers of liver regeneration following partial hepatectomy in the rat.

artículo científico publicado en 2010

Opening up the "Black Box": metabolic phenotyping and metabolome-wide association studies in epidemiology

artículo científico publicado en 2010

Optimization and evaluation of metabolite extraction protocols for untargeted metabolic profiling of liver samples by UPLC-MS.

artículo científico publicado en 2010

Optimized Phenotypic Biomarker Discovery and Confounder Elimination via Covariate-Adjusted Projection to Latent Structures from Metabolic Spectroscopy Data

artículo científico publicado en 2018

Optimized Preprocessing of Ultra-Performance Liquid Chromatography/Mass Spectrometry Urinary Metabolic Profiles for Improved Information Recovery

article

Optimizing the use of quality control samples for signal drift correction in large-scale urine metabolic profiling studies

artículo científico publicado en 2012

Orders of magnitude extension of the effective dynamic range of TDC-based TOFMS data through maximum likelihood estimation.

artículo científico publicado en 2014

Over-representation of correlation analysis (ORCA): a method for identifying associations between variable sets.

artículo científico publicado en 2014

PathIntegrate: Multivariate modelling approaches for pathway-based multi-omics data integration

artículo científico publicado en 2024

PhenoMeNal: Processing and analysis of Metabolomics data in the Cloud

scholarly article by Kristian Peters et al published 7 December 2018 in GigaScience

Piecewise multivariate modelling of sequential metabolic profiling data

artículo científico publicado en 2008

Power Analysis and Sample Size Determination in Metabolic Phenotyping

artículo científico publicado en 2016

Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the consortium on metabonomic toxicology screening approach

artículo científico publicado en 2007

Predictive modelling using pathway scores: robustness and significance of pathway collections

scientific article published on 04 November 2019

Processing and modeling of nuclear magnetic resonance (NMR) metabolic profiles

artículo científico publicado en 2011

Prospects for a statistical theory of LC/TOFMS data.

artículo científico publicado en 2012

Recent advances in mass spectrometry-based computational metabolomics

Recursive segment-wise peak alignment of biological (1)h NMR spectra for improved metabolic biomarker recovery

artículo científico publicado en 2009

Reliability of plasma polar metabolite concentrations in a large-scale cohort study using capillary electrophoresis-mass spectrometry.

artículo científico publicado en 2018

Robust algorithms for automated chemical shift calibration of 1D 1H NMR spectra of blood serum

artículo científico publicado en 2008

Serum metabolic signatures of coronary and carotid atherosclerosis and subsequent cardiovascular disease

artículo científico publicado en 2019

Statistical Correlations between NMR Spectroscopy and Direct Infusion FT-ICR Mass Spectrometry Aid Annotation of Unknowns in Metabolomics

artículo científico publicado en 2016

Statistical total correlation spectroscopy editing of 1H NMR spectra of biofluids: application to drug metabolite profile identification and enhanced information recovery.

artículo científico publicado en 2009

Subset Optimization by Reference Matching (STORM): An Optimized Statistical Approach for Recovery of Metabolic Biomarker Structural Information from 1H NMR Spectra of Biofluids

article

Synergistic and Antagonistic Mutation Responses of Human MCL-5 Cells to Mixtures of Benzo[a]pyrene and 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]pyridine: Dose-Related Variation in the Joint Effects of Common Dietary Carcinogens

artículo científico publicado en 2015

Temporal metabonomic modeling of l-arginine-induced exocrine pancreatitis

artículo científico publicado en 2008

The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements

artículo científico publicado en 2005

The association of fish consumption and its urinary metabolites with cardiovascular risk factors: the International Study of Macro-/Micronutrients and Blood Pressure (INTERMAP)

artículo científico publicado en 2020

The carcinoGENOMICS project: critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays

artículo científico publicado en 2008

The future of metabolomics in ELIXIR

artículo científico publicado en 2017

The future of metabolomics in ELIXIR.

artículo científico publicado en 2017

Untargeted Metabolome Quantitative Trait Locus Mapping Associates Variation in Urine Glycerate to Mutant Glycerate Kinase

article

Urinary metabolic signatures of human adiposity

artículo científico publicado en 2015

Use cases, best practice and reporting standards for metabolomics in regulatory toxicology

artículo científico publicado en 2019

We-P14:381 Metabonomics to assess self-reported data: The international study on macronutrients and blood pressure (INTERMAP)

article by R.L. Loo et al published January 2006 in Atherosclerosis. Supplements

Workflow for Integrated Processing of Multicohort Untargeted 1H NMR Metabolomics Data in Large-Scale Metabolic Epidemiology

artículo científico publicado en 2016

diXa: a data infrastructure for chemical safety assessment

artículo científico publicado en 2014

nmrML: a community supported open data standard for the description, storage, and exchange of NMR data

artículo científico publicado en 2017

Lista de obras de Tim Ebbels

1H NMR-based profiling reveals differential immune-metabolic networks during influenza virus infection in obese mice

A combination of transcriptomics and metabolomics uncovers enhanced bile acid biosynthesis in HepG2 cells expressing CCAAT/enhancer-binding protein β (C/EBPβ), hepatocyte nuclear factor 4α (HNF4α), and constitutive androstane receptor (CAR).

A comparison of human serum and plasma metabolites using untargeted 1H NMR spectroscopy and UPLC-MS

A statistical framework for biomarker discovery in metabolomic time course data ⬇️

A statistically rigorous test for the identification of parent-fragment pairs in LC-MS datasets

Analytic properties of statistical total correlation spectroscopy based information recovery in 1H NMR metabolic data sets

Analytical reproducibility in (1)H NMR-based metabonomic urinalysis

Applying 'omics technologies in chemicals risk assessment: Report of an ECETOC workshop.

Automated Annotation of Untargeted All-Ion Fragmentation LC–MS Metabolomics Data with MetaboAnnotatoR

Bayesian estimation of the number of protonation sites for urinary metabolites from NMR spectroscopic data.

COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access

Characterization of data analysis methods for information recovery from metabolic 1H NMR spectra using artificial complex mixtures

Cluster analysis statistical spectroscopy using nuclear magnetic resonance generated metabolic data sets from perturbed biological systems

Comparison of Bi- and Tri-Linear PLS Models for Variable Selection in Metabolomic Time-Series Experiments.

Computational Metabolomics: From Spectra to Knowledge (Dagstuhl Seminar 22181) ⬇️

Computational tools and workflows in metabolomics: An international survey highlights the opportunity for harmonisation through Galaxy

Data standards can boost metabolomics research, and if there is a will, there is a way

Data-Driven Approach for Metabolite Relationship Recovery in Biological 1H NMR Data Sets Using Iterative Statistical Total Correlation Spectroscopy ⬇️

Design and analysis of metabolomics studies in epidemiologic research: a primer on -omic technologies

Dietary and urinary metabonomic factors possibly accounting for higher blood pressure of black compared with white Americans: results of International Collaborative Study on macro-/micronutrients and blood pressure

Effect of the histone deacetylase inhibitor trichostatin a on the metabolome of cultured primary hepatocytes

Embedding standards in metabolomics: the Metabolomics Society data standards task group

Erratum to: COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access

Extraction and Integration of Genetic Networks from Short-Profile Omic Data Sets

Finding Correspondence between Metabolomic Features in Untargeted Liquid Chromatography–Mass Spectrometry Metabolomics Datasets

Genetic algorithms for simultaneous variable and sample selection in metabonomics

Geometric trajectory analysis of metabolic responses to toxicity can define treatment specific profiles

High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues

Intra- and Interlaboratory Reproducibility of Ultra Performance Liquid Chromatography–Time-of-Flight Mass Spectrometry for Urinary Metabolic Profiling

Meeting-in-the-middle using metabolic profiling - a strategy for the identification of intermediate biomarkers in cohort studies

MetAssimulo:Simulation of Realistic NMR Metabolic Profiles ⬇️

Metabolic Signatures of Gestational Weight Gain and Postpartum Weight Loss in a Lifestyle Intervention Study of Overweight and Obese Women

Metabolic phenotyping for discovery of urinary biomarkers of diet, xenobiotics and blood pressure in the INTERMAP Study: an overview.

Metabolic profiling and population screening of analgesic usage in nuclear magnetic resonance spectroscopy-based large-scale epidemiologic studies

Metabolic profiling and the metabolome-wide association study: significance level for biomarker identification

Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts

Metabolome-wide association study identifies multiple biomarkers that discriminate north and south Chinese populations at differing risks of cardiovascular disease: INTERMAP study

Metabolomics - the stethoscope for the 21st century

Metabonomic investigations into the global biochemical sequelae of exposure to the pancreatic toxin 1-cyano-2-hydroxy-3-butene in the rat.

Modelling short time series in metabolomics: a functional data analysis approach

Modelling the acid/base (1)H NMR chemical shift limits of metabolites in human urine

NMR-based metabolic profiling identifies biomarkers of liver regeneration following partial hepatectomy in the rat.

Opening up the "Black Box": metabolic phenotyping and metabolome-wide association studies in epidemiology

Optimization and evaluation of metabolite extraction protocols for untargeted metabolic profiling of liver samples by UPLC-MS.

Optimized Phenotypic Biomarker Discovery and Confounder Elimination via Covariate-Adjusted Projection to Latent Structures from Metabolic Spectroscopy Data

Optimized Preprocessing of Ultra-Performance Liquid Chromatography/Mass Spectrometry Urinary Metabolic Profiles for Improved Information Recovery

Optimizing the use of quality control samples for signal drift correction in large-scale urine metabolic profiling studies

Orders of magnitude extension of the effective dynamic range of TDC-based TOFMS data through maximum likelihood estimation.

Over-representation of correlation analysis (ORCA): a method for identifying associations between variable sets.

PathIntegrate: Multivariate modelling approaches for pathway-based multi-omics data integration

PhenoMeNal: Processing and analysis of Metabolomics data in the Cloud

Piecewise multivariate modelling of sequential metabolic profiling data

Power Analysis and Sample Size Determination in Metabolic Phenotyping

Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the consortium on metabonomic toxicology screening approach

Predictive modelling using pathway scores: robustness and significance of pathway collections

Processing and modeling of nuclear magnetic resonance (NMR) metabolic profiles

Prospects for a statistical theory of LC/TOFMS data.

Recent advances in mass spectrometry-based computational metabolomics

Recursive segment-wise peak alignment of biological (1)h NMR spectra for improved metabolic biomarker recovery

Reliability of plasma polar metabolite concentrations in a large-scale cohort study using capillary electrophoresis-mass spectrometry.

Robust algorithms for automated chemical shift calibration of 1D 1H NMR spectra of blood serum

Serum metabolic signatures of coronary and carotid atherosclerosis and subsequent cardiovascular disease

Statistical Correlations between NMR Spectroscopy and Direct Infusion FT-ICR Mass Spectrometry Aid Annotation of Unknowns in Metabolomics

Statistical total correlation spectroscopy editing of 1H NMR spectra of biofluids: application to drug metabolite profile identification and enhanced information recovery.

Subset Optimization by Reference Matching (STORM): An Optimized Statistical Approach for Recovery of Metabolic Biomarker Structural Information from 1H NMR Spectra of Biofluids

Synergistic and Antagonistic Mutation Responses of Human MCL-5 Cells to Mixtures of Benzo[a]pyrene and 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]pyridine: Dose-Related Variation in the Joint Effects of Common Dietary Carcinogens

Temporal metabonomic modeling of l-arginine-induced exocrine pancreatitis

The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements

The association of fish consumption and its urinary metabolites with cardiovascular risk factors: the International Study of Macro-/Micronutrients and Blood Pressure (INTERMAP)

The carcinoGENOMICS project: critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays

The future of metabolomics in ELIXIR

The future of metabolomics in ELIXIR.

Untargeted Metabolome Quantitative Trait Locus Mapping Associates Variation in Urine Glycerate to Mutant Glycerate Kinase

Urinary metabolic signatures of human adiposity

Use cases, best practice and reporting standards for metabolomics in regulatory toxicology

We-P14:381 Metabonomics to assess self-reported data: The international study on macronutrients and blood pressure (INTERMAP)

Workflow for Integrated Processing of Multicohort Untargeted 1H NMR Metabolomics Data in Large-Scale Metabolic Epidemiology

diXa: a data infrastructure for chemical safety assessment

nmrML: a community supported open data standard for the description, storage, and exchange of NMR data