Lista de obras - Chiara Ruzza - Dominio Público Uruguay

Anxiolytic- and panicolytic-like effects of Neuropeptide S in the mouse elevated T-maze

artículo científico publicado en 2012

Behavioural phenotypic characterization of CD-1 mice lacking the neuropeptide S receptor

artículo científico publicado en 2012

Beta-arrestin 2 rather than G protein efficacy determines the anxiolytic-versus antidepressant-like effects of nociceptin/orphanin FQ receptor ligands

artículo científico publicado en 2016

Biased versus Partial Agonism in the Search for Safer Opioid Analgesics

scientific article published on 25 August 2020

Blockade of nociceptin/orphanin FQ receptor signaling reverses LPS-induced depressive-like behavior in mice

artículo científico publicado en 2015

Further studies at neuropeptide s position 5: discovery of novel neuropeptide S receptor antagonists

artículo científico publicado en 2009

Further studies on the pharmacological profile of the neuropeptide S receptor antagonist SHA 68.

artículo científico publicado en 2010

In vitro and in vivo pharmacological characterization of Pronetupitant, a prodrug of the neurokinin 1 receptor antagonist Netupitant

artículo científico publicado en 2015

In vitro and in vivo pharmacological characterization of a neuropeptide S tetrabranched derivative.

artículo científico publicado en 2015

In vitro and in vivo pharmacological characterization of nociceptin/orphanin FQ tetrabranched derivatives.

artículo científico publicado en 2014

In vitro and in vivo pharmacological characterization of the neuropeptide s receptor antagonist [D-Cys(tBu)5]neuropeptide S

artículo científico publicado en 2009

In vitro and in vivo pharmacological characterization of the novel neuropeptide S receptor ligands QA1 and PI1.

artículo científico publicado en 2013

In vitro functional characterization of novel nociceptin/orphanin FQ receptor agonists in recombinant and native preparations.

artículo científico publicado en 2016

Neuropeptide S is a stimulatory anxiolytic agent: a behavioural study in mice

artículo científico publicado en 2008

Neuropeptide S receptor ligands: a patent review (2005-2016).

artículo científico publicado en 2016

Neuropeptide S reduces mouse aggressiveness in the resident/intruder test through selective activation of the neuropeptide S receptor.

artículo científico publicado en 2015

Pharmacological characterization of cebranopadol a novel analgesic acting as mixed nociceptin/orphanin FQ and opioid receptor agonist

scientific article published on 02 August 2016

Pharmacological characterization of tachykinin tetrabranched derivatives

artículo científico publicado en 2014

Pharmacological studies on the NOP and opioid receptor agonist PWT2-[Dmt1]N/OFQ(1-13).

artículo científico publicado en 2016

Racemic synthesis and solid phase peptide synthesis application of the chimeric valine/leucine derivative 2-amino-3,3,4-trimethyl-pentanoic acid

Spinal antinociceptive effects of the novel NOP receptor agonist PWT2-nociceptin/orphanin FQ in mice and monkeys

artículo científico publicado en 2015

Structure-activity study at positions 3 and 4 of human neuropeptide S.

artículo científico publicado en 2008

Synthesis and biological activity of human neuropeptide S analogues modified in position 2.

artículo científico publicado en 2008

Synthesis and biological activity of human neuropeptide S analogues modified in position 5: identification of potent and pure neuropeptide S receptor antagonists

artículo científico publicado en 2009

Synthesis and separation of the enantiomers of the neuropeptide S receptor antagonist (9R/S)-3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68).

artículo científico publicado en 2011

[d-Pen(p- t BuBzl)5]NPS, a novel ligand for the neuropeptide S receptor: structure activity and pharmacological studies

scholarly article by Chiara Ruzza et al published 11 February 2014 in Medicinal Chemistry Research

[tBu-D-Gly5]NPS, a pure and potent antagonist of the neuropeptide S receptor: in vitro and in vivo studies

artículo científico publicado en 2012

Lista de obras de Chiara Ruzza

Anxiolytic- and panicolytic-like effects of Neuropeptide S in the mouse elevated T-maze

Behavioural phenotypic characterization of CD-1 mice lacking the neuropeptide S receptor

Beta-arrestin 2 rather than G protein efficacy determines the anxiolytic-versus antidepressant-like effects of nociceptin/orphanin FQ receptor ligands

Biased versus Partial Agonism in the Search for Safer Opioid Analgesics

Blockade of nociceptin/orphanin FQ receptor signaling reverses LPS-induced depressive-like behavior in mice

Further studies at neuropeptide s position 5: discovery of novel neuropeptide S receptor antagonists

Further studies on the pharmacological profile of the neuropeptide S receptor antagonist SHA 68.

In vitro and in vivo pharmacological characterization of Pronetupitant, a prodrug of the neurokinin 1 receptor antagonist Netupitant

In vitro and in vivo pharmacological characterization of a neuropeptide S tetrabranched derivative.

In vitro and in vivo pharmacological characterization of nociceptin/orphanin FQ tetrabranched derivatives.

In vitro and in vivo pharmacological characterization of the neuropeptide s receptor antagonist [D-Cys(tBu)5]neuropeptide S

In vitro and in vivo pharmacological characterization of the novel neuropeptide S receptor ligands QA1 and PI1.

In vitro functional characterization of novel nociceptin/orphanin FQ receptor agonists in recombinant and native preparations.

Neuropeptide S is a stimulatory anxiolytic agent: a behavioural study in mice

Neuropeptide S receptor ligands: a patent review (2005-2016).

Neuropeptide S reduces mouse aggressiveness in the resident/intruder test through selective activation of the neuropeptide S receptor.

Pharmacological characterization of cebranopadol a novel analgesic acting as mixed nociceptin/orphanin FQ and opioid receptor agonist

Pharmacological characterization of tachykinin tetrabranched derivatives

Pharmacological studies on the NOP and opioid receptor agonist PWT2-[Dmt1]N/OFQ(1-13).

Racemic synthesis and solid phase peptide synthesis application of the chimeric valine/leucine derivative 2-amino-3,3,4-trimethyl-pentanoic acid

Spinal antinociceptive effects of the novel NOP receptor agonist PWT2-nociceptin/orphanin FQ in mice and monkeys

Structure-activity study at positions 3 and 4 of human neuropeptide S.

Synthesis and biological activity of human neuropeptide S analogues modified in position 2.

Synthesis and biological activity of human neuropeptide S analogues modified in position 5: identification of potent and pure neuropeptide S receptor antagonists

Synthesis and separation of the enantiomers of the neuropeptide S receptor antagonist (9R/S)-3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68).

[d-Pen(p- t BuBzl)5]NPS, a novel ligand for the neuropeptide S receptor: structure activity and pharmacological studies

[tBu-D-Gly5]NPS, a pure and potent antagonist of the neuropeptide S receptor: in vitro and in vivo studies