Lista de obras - Edward Tuddenham - Dominio Público Uruguay

A clinically useful DNA probe closely linked to haemophilia A ⬇️

artículo científico publicado el 7 de julio de 1984

A common ancestral glycoprotein (GP) 9 1828A>G (Asn45Ser) gene mutation occurring in European families from Australia and Northern Europe with Bernard-Soulier syndrome (BSS)

artículo científico publicado en 2005

A novel missense mutation in ABCA1 results in altered protein trafficking and reduced phosphatidylserine translocation in a patient with Scott syndrome.

artículo científico publicado en 2005

AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous hemorrhage.

artículo científico publicado en 2011

Adenovirus-associated virus vector-mediated gene transfer in hemophilia B

artículo científico publicado en 2011

Advances in Gene Therapy for Haemophilia

artículo científico publicado en 2017

Alpha1-antitrypsin Pittsburgh in a family with bleeding tendency

artículo científico publicado en 2009

Anticoagulation after liver transplantation: a retrospective audit and case-control study

artículo científico publicado en 2009

Autosomal dominant erythrocytosis and pulmonary arterial hypertension associated with an activating HIF2 alpha mutation.

artículo científico publicado en 2008

Changes in the levels of factor VIII and von Willebrand factor in the puerperium ⬇️

artículo científico publicado el 28 de septiembre de 2011

Characterisation of blood coagulation factor XI T475I.

artículo científico publicado en 2005

Characterisation of lymphocyte responses to Ca2+ in Scott syndrome

scientific article published on 01 February 2004

Codon optimization of human factor VIII cDNAs leads to high-level expression

artículo científico publicado en 2010

Combined deficiency of factor V and factor VIII is due to mutations in either LMAN1 or MCFD2

artículo científico publicado en 2005

Complete inhibition of acute humoral rejection using regulated expression of membrane-tethered anticoagulants on xenograft endothelium.

artículo científico publicado en 2004

Environmental and genetic factors influencing inhibitor development

artículo científico publicado en 2004

Epidemiology of coagulation disorders

artículo científico publicado el 1 de abril de 1992

Factor VIII - novel insights into form and function

artículo científico publicado en 2002

Factor VIII gene analysis in Japanese CRM‐positive and CRM‐reduced haemophilia A patients by single‐strand conformation polymorphism ⬇️

artículo científico publicado el 1 de septiembre de 1997

Factor VIII gene mutations found by a comparative study of SSCP, DGGE and CMC and their analysis on a molecular model of factor VIII protein ⬇️

artículo científico publicado el 1 de diciembre de 1997

Functional characterization of factor V-Ile359Thr: a novel mutation associated with thrombosis

scientific article published on 24 December 2003

Gene Therapy for Hemophilia.

artículo científico publicado en 2017

Genotype-phenotype correlation in combined deficiency of factor V and factor VIII.

artículo científico publicado en 2008

Human congenital diseases with mixed modes of inheritance have a shortage of recessive disease. A demographic scenario?

artículo científico publicado en 2011

Identification of factor IX mutations in Iranian haemophilia B patients by SSCP and sequencing

artículo científico publicado en 2006

Identification of two novel mutations in non‐Jewish factor XI deficiency ⬇️

artículo científico publicado el 1 de agosto de 1995

In search of the source of factor VIII.

artículo científico publicado en 2014

Inactivation of factor VIII by factor IXa

artículo científico publicado el 17 de marzo de 1992

Inhibition of coagulation by macromolecular complexes.

artículo científico publicado en 2005

Inhibition of intravascular thrombosis in murine endotoxemia by targeted expression of hirudin and tissue factor pathway inhibitor analogs to activated endothelium

artículo científico publicado en 2004

Journal rubric. Haemophilic pseudotumour of the carotid artery

artículo científico publicado en 2012

Killing 2 birds with 1 stone

scientific article published on 01 October 2008

Letter: Endothelial cells and factor VIII-related protein ⬇️

artículo científico publicado el 3 de enero de 1976

Lipogranuloma of the breast due to phenothiazine therapy ⬇️

artículo científico

Live birth following the first mutation specific pre-implantation genetic diagnosis for haemophilia A.

artículo científico publicado en 2006

Long-term safety and efficacy of factor IX gene therapy in hemophilia B.

artículo científico publicado en 2014

Menorrhagia in adolescents with inherited bleeding disorders.

scientific article published on 14 May 2010

Molecular evolution of the vertebrate blood coagulation network.

artículo científico publicado en 2003

Monitoring low dose recombinant factor VIIa therapy in patients with severe factor XI deficiency undergoing surgery

artículo científico publicado en 2011

Monoclonal antibodies to human factor VII: a one step immunoradiometric assay for VII:Ag ⬇️

artículo científico publicado el 1 de marzo de 1988

Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2

artículo científico publicado en 2004

Noninvasive prenatal diagnosis of hemophilia by microfluidics digital PCR analysis of maternal plasma DNA.

artículo científico publicado en 2011

Permanent phenotypic correction of hemophilia B in immunocompetent mice by prenatal gene therapy.

artículo científico publicado en 2004

Pharmacodynamic resistance to warfarin associated with a Val66Met substitution in vitamin K epoxide reductase complex subunit 1.

artículo científico publicado en 2005

Purified factor VIII ⬇️

artículo científico publicado el 19 de agosto de 1995

RNA as drug and antidote

scientific article published in Nature

Recent advances in developing specific therapies for haemophilia

artículo científico publicado en 2018

Safe and efficient transduction of the liver after peripheral vein infusion of self-complementary AAV vector results in stable therapeutic expression of human FIX in nonhuman primates

artículo científico publicado en 2006

Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver

artículo científico publicado en 2005

Solution structure of the major factor VIII binding region on von Willebrand factor

artículo científico publicado en 2014

Structural analysis of eight novel and 112 previously reported missense mutations in the interactive FXI mutation database reveals new insight on FXI deficiency

artículo científico publicado en 2009

Structure of human factor VIII

scientific journal article

The Locus for Combined Factor V-Factor VIII Deficiency (F5F8D) Maps to 18q21, between D18S849 and D18S1103 ⬇️

artículo científico publicado el 1 de julio de 1997

The factor VIII Structure and Mutation Resource Site: HAMSTeRS version 4 ⬇️

artículo científico publicado el 1 de enero de 1998

Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variant

artículo científico publicado en 2013

Thrombin generation assay identifies individual variability in responses to low molecular weight heparin in pregnancy: implications for anticoagulant monitoring.

artículo científico publicado en 2014

Tissue Localization and Synthesis of Factor-VIII-Related Antigen in the Human Foetus ⬇️

artículo científico publicado el 1 de abril de 1974

Two novel mutations in severe factor VII deficiency

artículo científico publicado en 2004

Use of a non-depleting anti-CD4 antibody to modulate the immune response to coagulation factors VIII and IX.

artículo científico publicado en 2002

Lista de obras de Edward Tuddenham

A clinically useful DNA probe closely linked to haemophilia A ⬇️

A common ancestral glycoprotein (GP) 9 1828A>G (Asn45Ser) gene mutation occurring in European families from Australia and Northern Europe with Bernard-Soulier syndrome (BSS)

A novel missense mutation in ABCA1 results in altered protein trafficking and reduced phosphatidylserine translocation in a patient with Scott syndrome.

AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous hemorrhage.

Adenovirus-associated virus vector-mediated gene transfer in hemophilia B

Advances in Gene Therapy for Haemophilia

Alpha1-antitrypsin Pittsburgh in a family with bleeding tendency

Anticoagulation after liver transplantation: a retrospective audit and case-control study

Autosomal dominant erythrocytosis and pulmonary arterial hypertension associated with an activating HIF2 alpha mutation.

Changes in the levels of factor VIII and von Willebrand factor in the puerperium ⬇️

Characterisation of blood coagulation factor XI T475I.

Characterisation of lymphocyte responses to Ca2+ in Scott syndrome

Codon optimization of human factor VIII cDNAs leads to high-level expression

Combined deficiency of factor V and factor VIII is due to mutations in either LMAN1 or MCFD2

Complete inhibition of acute humoral rejection using regulated expression of membrane-tethered anticoagulants on xenograft endothelium.

Environmental and genetic factors influencing inhibitor development

Epidemiology of coagulation disorders

Factor VIII - novel insights into form and function

Factor VIII gene analysis in Japanese CRM‐positive and CRM‐reduced haemophilia A patients by single‐strand conformation polymorphism ⬇️

Factor VIII gene mutations found by a comparative study of SSCP, DGGE and CMC and their analysis on a molecular model of factor VIII protein ⬇️

Functional characterization of factor V-Ile359Thr: a novel mutation associated with thrombosis

Gene Therapy for Hemophilia.

Genotype-phenotype correlation in combined deficiency of factor V and factor VIII.

Human congenital diseases with mixed modes of inheritance have a shortage of recessive disease. A demographic scenario?

Identification of factor IX mutations in Iranian haemophilia B patients by SSCP and sequencing

Identification of two novel mutations in non‐Jewish factor XI deficiency ⬇️

In search of the source of factor VIII.

Inactivation of factor VIII by factor IXa

Inhibition of coagulation by macromolecular complexes.

Inhibition of intravascular thrombosis in murine endotoxemia by targeted expression of hirudin and tissue factor pathway inhibitor analogs to activated endothelium

Journal rubric. Haemophilic pseudotumour of the carotid artery

Killing 2 birds with 1 stone

Letter: Endothelial cells and factor VIII-related protein ⬇️

Lipogranuloma of the breast due to phenothiazine therapy ⬇️

Live birth following the first mutation specific pre-implantation genetic diagnosis for haemophilia A.

Long-term safety and efficacy of factor IX gene therapy in hemophilia B.

Menorrhagia in adolescents with inherited bleeding disorders.

Molecular evolution of the vertebrate blood coagulation network.

Monitoring low dose recombinant factor VIIa therapy in patients with severe factor XI deficiency undergoing surgery

Monoclonal antibodies to human factor VII: a one step immunoradiometric assay for VII:Ag ⬇️

Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2

Noninvasive prenatal diagnosis of hemophilia by microfluidics digital PCR analysis of maternal plasma DNA.

Permanent phenotypic correction of hemophilia B in immunocompetent mice by prenatal gene therapy.

Pharmacodynamic resistance to warfarin associated with a Val66Met substitution in vitamin K epoxide reductase complex subunit 1.

Purified factor VIII ⬇️

RNA as drug and antidote

Recent advances in developing specific therapies for haemophilia

Safe and efficient transduction of the liver after peripheral vein infusion of self-complementary AAV vector results in stable therapeutic expression of human FIX in nonhuman primates

Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver

Solution structure of the major factor VIII binding region on von Willebrand factor

Structural analysis of eight novel and 112 previously reported missense mutations in the interactive FXI mutation database reveals new insight on FXI deficiency

Structure of human factor VIII

The Locus for Combined Factor V-Factor VIII Deficiency (F5F8D) Maps to 18q21, between D18S849 and D18S1103 ⬇️

The factor VIII Structure and Mutation Resource Site: HAMSTeRS version 4 ⬇️

Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variant

Thrombin generation assay identifies individual variability in responses to low molecular weight heparin in pregnancy: implications for anticoagulant monitoring.

Tissue Localization and Synthesis of Factor-VIII-Related Antigen in the Human Foetus ⬇️

Two novel mutations in severe factor VII deficiency

Use of a non-depleting anti-CD4 antibody to modulate the immune response to coagulation factors VIII and IX.