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Lista de obras de Isabel Santos

(99m)Tc-tricarbonyl complexes functionalized with anthracenyl fragments: synthesis, characterization, and evaluation of their radiotoxic effects in murine melanoma cells

artículo científico publicado en 2009

13- and 14-membered macrocyclic ligands containing methylcarboxylate or methylphosphonate pendant arms: chemical and biological evaluation of their (153)Sm and (166)Ho complexes as potential agents for therapy or bone pain palliation

artículo científico publicado en 2006

153Sm and 166Ho complexes with tetraaza macrocycles containing pyridine and methylcarboxylate or methylphosphonate pendant arms

artículo científico publicado en 2004

99mTc(CO)3-labeled pamidronate and alendronate for bone imaging.

artículo científico publicado en 2011

99mTc(I) scorpionate complexes for brain imaging: synthesis, characterization and biological evaluation

artículo científico publicado en 2012

99mTc(I)/Re(I) tricarbonyl complexes for in vivo targeting of melanotic melanoma: Synthesis and biological evaluation

artículo científico publicado en 2012

99mTcI/ReI Tricarbonyl Complexes with Tridentate Cysteamine Based Ligands: Synthesis, Characterization and in vitro/in vivo Evaluation

A novel tetraazamacrocycle bearing a thiol pendant arm for labeling biomolecules with radiolanthanides.

artículo científico publicado en 2009

A quinazoline-derivative DOTA-type gallium(III) complex for targeting epidermal growth factor receptors: synthesis, characterisation and biological studies

artículo científico publicado en 2008

Biological assessment of novel bisphosphonate-containing 99mTc/Re-organometallic complexes

Biological evaluation of 153Sm and 166Ho complexes with tetraazamacrocycles containing methylcarboxylate and/or methylphosphonate pendant arms

Bisphosphonates as radionuclide carriers for imaging or systemic therapy.

artículo científico publicado en 2011

Cationic Re(V) Oxo Complexes with Poly(pyrazolyl)borates: Synthesis, Characterization, and Stability

artículo científico publicado en 2000

Cellular uptake mechanisms of an antitumor ruthenium compound: the endosomal/lysosomal system as a target for anticancer metal-based drugs

artículo científico publicado en 2013

Chemical and biological evaluation of 153Sm and 166Ho complexes of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylphosphonic acid monoethylester) (H4 dotp OEt).

artículo científico publicado en 2008

Chemical, radiochemical and biological studies of Sm and Ho complexes of H4dota analogues containing one methylphosphonic/phosphinic acid pendant arm

Copper(II) complexes with tridentate pyrazole-based ligands: synthesis, characterization, DNA cleavage activity and cytotoxicity

artículo científico publicado en 2011

Coupling of a sheep anti-T3 IgG to a solid phase for a triiodothyronine radioimmunoassay

Cytotoxic gold compounds: synthesis, biological characterization and investigation of their inhibition properties of the zinc finger protein PARP-1.

artículo científico publicado en 2012

Disruption of Unprecedented B-H…M Agostic Interactions: An Alternative Approach for Labeling Bioactive Molecules

Dramatic effect of the tridentate ligand on the stability of 99mTC "3 + 1" oxo complexes bearing arylpiperazine derivatives.

artículo científico publicado en 2005

Estrogen receptor ligands for targeting breast tumours: a brief outlook on radioiodination strategies

artículo científico publicado en 2012

Evaluation of Novel Radioiodinated C7-substituted Δ6,7 – estradiol Derivatives for Molecular Recognition of ER-Positive Breast Tumours

article published in 2009

Evaluation of novel 99mTc(I)-labeled homobivalent α-melanocyte-stimulating hormone analogs for melanocortin-1 receptor targeting

scientific article published on 01 April 2012

Important cytotoxicity of novel iron(II) cyclopentadienyl complexes with imidazole based ligands.

artículo científico publicado en 2013

In vitro and in vivo evaluation of a novel 99mTc(CO)3-pyrazolyl conjugate of cyclo-(Arg-Gly-Asp-d-Tyr-Lys).

artículo científico publicado en 2007

Influence of the bifunctional chelator on the pharmacokinetic properties of 99mTc(CO)3-labeled cyclic α-melanocyte stimulating hormone analog.

artículo científico publicado en 2013

Influence of the ligand donor atoms on the in vitro stability of rhenium(I) and technetium (I)-99m complexes with pyrazole-containing chelators: Experimental and DFT studies

scholarly article by Carolina Moura et al published March 2009 in Journal of Organometallic Chemistry

Insights into the structural determinants for selective inhibition of nitric oxide synthase isoforms

artículo científico publicado en 2012

Iodo bis bistrimethylsilylamido lanthanides

Lanthanide(III) complexes of 4,10-bis(phosphonomethyl)-1,4,7,10-tetraazacyclododecane-1,7-diacetic acid (trans-H6do2a2p) in solution and in the solid state: structural studies along the series

artículo científico publicado en 2010

Mannosylated dextran derivatives labeled with fac-[M(CO)₃]+ (M = (99m)Tc, Re) for specific targeting of sentinel lymph node

scientific article published on 23 February 2011

Melanoma targeting with alpha-melanocyte stimulating hormone analogs labeled with fac-[99mTc(CO)3]+: effect of cyclization on tumor-seeking properties.

artículo científico publicado en 2008

Metal-Based Inhibition of Poly(ADP-ribose) Polymerase − The Guardian Angel of DNA

artículo científico publicado el 3 de marzo de 2011

Metalloprobes for functional monitoring of tumour multidrug resistance by nuclear imaging

artículo científico publicado en 2011

Mixed-Ligand Rhenium Tricarbonyl Complexes Anchored on a (κ2-H,S) Trihydro(mercaptoimidazolyl)borate: A Missing Binding Motif for Soft Scorpionates

scholarly article by Margarida Videira et al published March 2008 in Organometallics

Mono- and dicationic Re(I)/(99m)Tc(I) tricarbonyl complexes for the targeting of energized mitochondria

artículo científico publicado en 2013

New (99m)Tc(CO)(3) mannosylated dextran bearing S-derivatized cysteine chelator for sentinel lymph node detection.

artículo científico publicado en 2012

New bifunctional metalloproteinase inhibitors: an integrated approach towards biological improvements and cancer therapy

artículo científico publicado en 2013

New polydentate Ru(III)-Salan complexes: Synthesis, characterization, anti-tumour activity and interaction with human serum proteins

New water-soluble ruthenium(II) cytotoxic complex: biological activity and cellular distribution

artículo científico publicado en 2013

Novel 3+1 mixed-ligand Technetium-99m complexes carrying dipeptides as monodentate ligands

artículo científico publicado en 2004

Novel 7α-alkoxy-17α-(4'-halophenylethynyl)estradiols as potential SPECT/PET imaging agents for estrogen receptor expressing tumours: synthesis and binding affinity evaluation.

artículo científico publicado en 2012

Novel estradiol based metal complexes of Tc-99m for breast cancer imaging

scholarly article by Carina Neto et al published August 2010 in Nuclear Medicine and Biology

Novel estradiol based metal complexes of Tc-99m.

artículo científico publicado en 2012

Nuclear targeting with cell-specific multifunctional tricarbonyl M(I) (M is Re, (99m)Tc) complexes: synthesis, characterization, and cell studies

artículo científico publicado en 2011

Preparation and biological evaluation of cyclopentadienyl-based 99mTc-complexes [(Cp-R)99mTc(CO)3] mimicking benzamides for malignant melanoma targeting

artículo científico publicado en 2010

Pt(II) complexes with bidentate and tridentate pyrazolyl-containing chelators: synthesis, structural characterization and biological studies.

artículo científico publicado en 2011

Pyrazolyl conjugates of bombesin: a new tridentate ligand framework for the stabilization of fac-[M(CO)3]+ moiety

scientific article published on 02 May 2006

Pyrazolyl derivatives as bifunctional chelators for labeling tumor-seeking peptides with the fac-[M(CO)3]+ moiety (M = 99mTc, Re): synthesis, characterization, and biological behavior.

artículo científico publicado en 2005

Pyrazolyl-diamine ligands that bear anthracenyl moieties and their rhenium(I) tricarbonyl complexes: synthesis, characterisation and DNA-binding properties

artículo científico publicado en 2008

Radiochemical and biological behaviour of 153Sm and 166Ho complexes anchored by a novel bis(methylphosphonate) tetraazamacrocycle

Radiochemical and biological evaluation of novel153Sm/166Ho-amino acid-chitosan complexes

Radiohalogenated 4-anilinoquinazoline-based EGFR-TK inhibitors as potential cancer imaging agents

artículo científico publicado en 2011

Radioiodinated ligands for the estrogen receptor: effect of different 7-cyanoalkyl chains on the binding affinity of novel iodovinyl-6-dehydroestradiols

artículo científico publicado en 2008

Radioiodinated sunitinib as a potential radiotracer for imaging angiogenesis-radiosynthesis and first radiopharmacological evaluation of 5-[125I]Iodo-sunitinib.

artículo científico publicado en 2012

Radioiodination of new EGFR inhibitors as potential SPECT agents for molecular imaging of breast cancer

artículo científico publicado en 2007

Radiometallated peptides for molecular imaging and targeted therapy.

artículo científico publicado en 2011

Radiopharmaceuticals for targeted radiotherapy

artículo científico publicado en 2005

Radiosynthesis and in vivo evaluation of a ¹⁸F-labelled styryl-benzoxazole derivative for β-amyloid targeting

artículo científico publicado en 2013

Rapid hepatic clearance of 99mTc-TMEOP: a new candidate for myocardial perfusion imaging.

artículo científico publicado en 2010

Re and Tc tricarbonyl complexes: from the suppression of NO biosynthesis in macrophages to in vivo targeting of inducible nitric oxide synthase.

artículo científico publicado en 2010

Reactivity of [Re[kappa(3)-H(mu-H)B(tim(Me))(2)](CO)(3)] (tim(Me) = 2-mercapto-1-methylimidazolyl) toward neutral substrates.

artículo científico publicado en 2002

Rhenium oxocomplexes with the heteroscorpionate phenyltris(pyrazolyl)borate: synthesis and structural studies

scholarly article by Raquel Garcia et al published January 2003 in Inorganica Chimica Acta

Rhenium(I) organometallic complexes with novel bis(mercaptoimidazolyl)borates and with hydrotris(mercaptoimidazolyl)borate: chemical and structural studies

scholarly article by Raquel Garcia et al published August 2001 in Journal of Organometallic Chemistry

Screening organometallic binuclear thiosemicarbazone ruthenium complexes as potential anti-tumour agents: cytotoxic activity and human serum albumin binding mechanism

artículo científico publicado en 2013

Silylated mixed-ligand rhenium complexes with the [PNS/S] donor atom set

scholarly article by Torsten Kniess et al published May 2003 in Inorganica Chimica Acta

Studies of the myocardial uptake and excretion mechanisms of a novel 99mTc heart perfusion agent

artículo científico publicado el 12 de noviembre de 2011

Synthesis and biological evaluation of tricarbonyl Re(I) and Tc(I) complexes anchored by poly(azolyl)borates: application on the design of radiopharmaceuticals for the targeting of 5-HT1A receptors

artículo científico publicado en 2006

Synthesis and biological studies of pyrazolyl-diamine Pt(II) complexes containing polyaromatic DNA-binding groups

artículo científico publicado en 2012

Synthesis and characterization of rhenium and technetium-99m tricarbonyl complexes bearing the 4-[3-bromophenyl]quinazoline moiety as a biomarker for EGFR-TK imaging.

artículo científico publicado en 2009

Synthesis and structural characterization of novel Re(i) tricarbonyl complexes anchored on a phosphinoarylbenzylamine and a phosphinoaryloxazoline generated in situ.

artículo científico publicado en 2003

Synthesis and structural characterization of unprecedented bis-asymmetric heteroscorpionate U(III) complexes: [U(kappa3-H2B(pztBu,Me)(pzMe,tBu))2I] and [U(kappa3-H2B(pztBu,Me)(pzMe2))2I].

artículo científico publicado en 2003

Synthesis and structural studies of rhenium(I) tricarbonyl complexes with thione containing chelators

scholarly article by Leonor Maria et al published November 2006 in Journal of Organometallic Chemistry

Synthesis of organometallic ruthenium(II) complexes with strong activity against several human cancer cell lines

artículo científico publicado en 2012

Synthesis, characterization and biological evaluation of In(III) complexes anchored by DOTA-like chelators bearing a quinazoline moiety

artículo científico publicado en 2010

Synthesis, characterization and biological evaluation of tricarbonyl M(i) (M = Re, 99mTc) complexes functionalized with melanin-binding pharmacophores

Synthesis, characterization and cytotoxic activity of gallium(III) complexes anchored by tridentate pyrazole-based ligands

artículo científico publicado en 2010

Synthesis, characterization, and evaluation of a novel 99mTc(CO)3 pyrazolyl conjugate of a peptide nucleic acid sequence

artículo científico publicado en 2008

Synthesis, structure and solution behaviour of U(III) poly(3,5-diisopropylpyrazoly)borate complexes

TETA analogue containing one methylenephosphonate pendant arm: Lanthanide complexes and biological evaluation of its 153Sm and 166Ho complexes.

artículo científico publicado en 2010

Target-specific Tc(CO)3-complexes for in vivo imaging

article published in 2013

The [(Cp)M(CO)(3)] (M=Re, (99m)Tc) building block for imaging agents and bioinorganic probes: perspectives and limitations.

artículo científico publicado en 2012

The role of neutral coligands on the stabilization of mono-Tp(i)Pr2 U(III) complexes

artículo científico publicado en 2004

Theoretical studies on the binding of rhenium(I) complexes to inducible nitric oxide synthase

artículo científico publicado en 2013

Towards 99mTc-based imaging agents with effective doxorubicin mimetics: a molecular and cellular study

artículo científico publicado en 2016

Tricarbonyl M(I) (M = Re, (99m)Tc) complexes bearing acridine fluorophores: synthesis, characterization, DNA interaction studies and nuclear targeting

artículo científico publicado en 2010

Tris(pyrazolyl)methane 99mtc tricarbonyl complexes for myocardial imaging

artículo científico publicado en 2009

Unique Uranium(III) Cations Anchored by Polydentate Sulfur-Based Ligands: Synthesis and Structure of [U{H(R)B(timMe)2}2(THF)3][BPh4] (R = H, Ph)

artículo científico publicado en 2001

Uranium iodides as catalysts for Diels–Alder reactions

scholarly article by Jacqueline Collin et al published October 2000 in Journal of Molecular Catalysis A

[(Cp-R)M(CO)3] (M=Re or 99mTc) Arylsulfonamide, arylsulfamide, and arylsulfamate conjugates for selective targeting of human carbonic anhydrase IX

artículo científico publicado en 2012

[RuII(η⁵-C₅H₅)(bipy)(PPh₃)]⁺, a promising large spectrum antitumor agent: cytotoxic activity and interaction with human serum albumin.

artículo científico publicado en 2012