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Lista de obras de Mitch Dowsett

10th International Aromatase Conference Proceedings, September 2010. Preface

artículo científico publicado en 2011

11 years' follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive early breast cancer: final analysis of the HERceptin Adjuvant (HERA) trial

artículo científico publicado en 2017

2 years versus 1 year of adjuvant trastuzumab for HER2-positive breast cancer (HERA): an open-label, randomised controlled trial

artículo científico publicado en 2013

2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: a randomised controlled trial

artículo científico publicado en 2007

20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years

artículo científico publicado en 2017

A dual-center randomized controlled double blind trial assessing the effect of acupuncture in reducing musculoskeletal symptoms in breast cancer patients taking aromatase inhibitors ⬇️

artículo científico publicado el 8 de febrero de 2013

A gene expression signature from human breast cancer cells with acquired hormone independence identifies MYC as a mediator of antiestrogen resistance

artículo científico publicado en 2011

A luminal breast cancer genome atlas: progress and barriers

artículo científico publicado en 2007

A marker of homologous recombination predicts pathologic complete response to neoadjuvant chemotherapy in primary breast cancer

artículo científico publicado en 2010

A poetic story: lessons learnt from the world's largest breast cancer window of opportunity study.

artículo científico publicado en 2015

Abstract P3-06-01: Nuclear β-catenin negativity predicts for late relapse in ER+, tamoxifen-treated breast cancer

Abstract S1-04: Exome sequencing of post-menopausal ER+ breast cancer (BC) treated pre-surgically with aromatase inhibitors (AIs) in the POETIC trial (CRUK/07/015)

Abstract S3-01: The TNT trial: A randomized phase III trial of carboplatin (C) compared with docetaxel (D) for patients with metastatic or recurrent locally advanced triple negative or BRCA1/2 breast cancer (CRUK/07/012)

artículo científico publicado en 2015

Accurate Prediction and Validation of Response to Endocrine Therapy in Breast Cancer

artículo científico publicado en 2015

Adjuvant aromatase inhibitors for early breast cancer after chemotherapy-induced amenorrhoea: caution and suggested guidelines

scientific article published on 01 June 2006

Adjuvant use of anastrozole in breast cancer

artículo científico publicado en 2004

American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer

artículo científico publicado en 2010

American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer (unabridged version).

artículo científico publicado en 2010

An international Ki67 reproducibility study

artículo científico publicado en 2013

An international study to increase concordance in Ki67 scoring

artículo científico publicado en 2015

Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer.

artículo científico publicado en 2015

Analytical validation of a standardized scoring protocol for Ki67: phase 3 of an international multicenter collaboration

artículo científico publicado en 2016

Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): an international, double-blind, randomised placebo-controlled trial

artículo científico publicado en 2013

Aromatase and its inhibitors: significance for breast cancer therapy

artículo científico publicado en 2002

Aromatase inhibitors for breast cancer: lessons from the laboratory

artículo científico publicado en 2003

Aromatase inhibitors in breast cancer

artículo científico publicado en 2003

Aromatase inhibitors: combinations with fulvestrant or signal transduction inhibitors as a strategy to overcome endocrine resistance

artículo científico publicado en 2005

Assessment of Ki67 in Breast Cancer: Recommendations from the International Ki67 in Breast Cancer Working Group ⬇️

artículo científico publicado el 29 de septiembre de 2011

Assessment of the Spatial Heterogeneity of Breast Cancers: Associations Between Computed Tomography and Immunohistochemistry.

artículo científico publicado en 2019

Association between breast cancer subtypes and response to neoadjuvant anastrozole

artículo científico publicado en 2011

Association between endogenous plasma hormone concentrations and fracture risk in men and women: the EPIC-Oxford prospective cohort study

artículo científico publicado en 2009

Associations of endogenous testosterone and SHBG with glycated haemoglobin in middle-aged and older men

article

Author Correction: The prognostic effects of somatic mutations in ER-positive breast cancer

scientific article published in Nature Communications

BCL-2: a new therapeutic target in estrogen receptor-positive breast cancer?

artículo científico publicado en 2013

BRCA1/BRCA2 mutation status and analysis of cancer family history in participants of the Royal Marsden Hospital tamoxifen chemoprevention trial

article

Biological characteristics of the pure antiestrogen fulvestrant: overcoming endocrine resistance

artículo científico publicado en 2005

Biomarker analysis of the NeoSphere study: pertuzumab, trastuzumab, and docetaxel versus trastuzumab plus docetaxel, pertuzumab plus trastuzumab, or pertuzumab plus docetaxel for the neoadjuvant treatment of HER2-positive breast cancer

artículo científico publicado en 2017

Biomarker changes during neoadjuvant anastrozole, tamoxifen, or the combination: influence of hormonal status and HER-2 in breast cancer--a study from the IMPACT trialists

artículo científico publicado en 2005

Biomarker investigations from the ATAC trial: the role of TA01.

artículo científico publicado en 2004

Biomarkers for the clinical management of breast cancer: International perspective ⬇️

artículo científico publicado el 8 de febrero de 2013

Birthweight and body size throughout life in relation to sex hormones and prolactin concentrations in premenopausal women

artículo científico publicado en 2006

Breast cancer biomarkers in clinical testing: analysis of a UK national external quality assessment scheme for immunocytochemistry and in situ hybridisation database containing results from 199 300 patients

article published in 2018

Breast cancer molecular profiling with single sample predictors: a retrospective analysis

artículo científico publicado en 2010

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.

artículo científico publicado en 2016

Breast cancer: aromatase inhibitors take on tamoxifen

artículo científico publicado en 2002

CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer

artículo científico publicado en 2015

CYP2D6 Genotype Should Not Be Used for Deciding About Tamoxifen Therapy in Postmenopausal Breast Cancer ⬇️

artículo científico publicado el 17 de junio de 2013

CYP2D6 and UGT2B7 genotype and risk of recurrence in tamoxifen-treated breast cancer patients

artículo científico publicado en 2012

CYP3A variation, premenopausal estrone levels, and breast cancer risk

artículo científico publicado en 2012

Cell filtration‐laser scanning cytometry for the characterisation of circulating breast cancer cells ⬇️

artículo científico publicado el 1 de octubre de 2003

Changes in Expression of Genes Representing Key Biologic Processes after Neoadjuvant Chemotherapy in Breast Cancer, and Prognostic Implications in Residual Disease.

artículo científico publicado en 2016

Changes in bone mineral density at 3 years in postmenopausal women receiving anastrozole and risedronate in the IBIS-II bone substudy: an international, double-blind, randomised, placebo-controlled trial

artículo científico publicado en 2014

Changes in estradiol and testosterone levels in postmenopausal women after changes in body mass index

artículo científico publicado en 2013

Childhood body size and pubertal timing in relation to adult mammographic density phenotype

artículo científico publicado en 2017

Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancer

artículo científico publicado en 2016

Cigarette Smoking and Endogenous Sex Hormones in Postmenopausal Women

article

Circulating tumour cells in breast cancer

artículo científico publicado en 2004

Clinical and Biochemical Consequences of CYP17A1 Inhibition with Abiraterone Given with and without Exogenous Glucocorticoids in Castrate Men with Advanced Prostate Cancer

scholarly article by Gerhardt Attard et al published February 2012 in The Journal of Clinical Endocrinology and Metabolism

Clinical strategies for rationale combinations of aromatase inhibitors with novel therapies for breast cancer

artículo científico publicado en 2007

Combined quantitative measures of ER, PR, HER2, and KI67 provide more prognostic information than categorical combinations in luminal breast cancer.

artículo científico publicado en 2019

Comparative Efficacy and Safety of Adjuvant Letrozole Versus Anastrozole in Postmenopausal Patients With Hormone Receptor-Positive, Node-Positive Early Breast Cancer: Final Results of the Randomized Phase III Femara Versus Anastrozole Clinical Evalu

artículo científico publicado en 2017

Comparison of EndoPredict and EPclin With Oncotype DX Recurrence Score for Prediction of Risk of Distant Recurrence After Endocrine Therapy.

scientific article published on 10 July 2016

Comparison of methods to measure low serum estradiol levels in postmenopausal women

artículo científico publicado en 2006

Comparison of protein expression between formalin-fixed core-cut biopsies and surgical excision specimens using a novel multiplex approach.

artículo científico publicado en 2019

Comparison of the Performance of 6 Prognostic Signatures for Estrogen Receptor-Positive Breast Cancer: A Secondary Analysis of a Randomized Clinical Trial

artículo científico publicado en 2018

Comparison of the selective estrogen receptor modulator arzoxifene (LY353381) with tamoxifen on tumor growth and biomarker expression in an MCF-7 human breast cancer xenograft model ⬇️

artículo científico publicado el 1 de octubre de 2003

Correlation between cyclooxygenase-2 expression and angiogenesis in human breast cancer.

artículo científico publicado en 2003

Correlation of Age and HRT Use with Breast Density as Assessed by Quantra™ ⬇️

artículo científico publicado el 10 de diciembre de 2012

Critical assessment of new risk factors for breast cancer: considerations for development of an improved risk prediction model

artículo científico publicado en 2007

Cross Stratification and Differential Risk by Breast Cancer Index and Recurrence Score in women with hormone receptor positive lymph-node negative early stage breast cancer

artículo científico publicado en 2016

Current and emerging biomarkers in breast cancer: prognosis and prediction

artículo científico publicado en 2010

Current perspectives on HER2 testing: a review of national testing guidelines

artículo científico publicado en 2003

Current status of HER2 testing

artículo científico publicado en 2002

Cyclin D1 protein overexpression and CCND1 amplification in breast carcinomas: an immunohistochemical and chromogenic in situ hybridisation analysis

artículo científico publicado en 2006

Deficits in plasma oestradiol measurement in studies and management of breast cancer

artículo científico publicado en 2004

Designing the future shape of breast cancer diagnosis, prognosis and treatment

artículo científico

Differences in expression of proliferation-associated genes and RANKL across the menstrual cycle in estrogen receptor-positive primary breast cancer

artículo científico publicado en 2014

Digital mammographic density and breast cancer risk: a case-control study of six alternative density assessment methods

artículo científico publicado en 2014

Discordance between oncotype DX recurrence score and RSPC for predicting residual risk of recurrence in ER-positive breast cancer

artículo científico publicado en 2017

Disease-free survival according to degree of HER2 amplification for patients treated with adjuvant chemotherapy with or without 1 year of trastuzumab: the HERA Trial

artículo científico publicado en 2009

ER and HER2 expression are positively correlated in HER2 non-overexpressing breast cancer ⬇️

artículo científico publicado en 2012

ERBB2 influences the subcellular localization of the estrogen receptor in tamoxifen-resistant MCF-7 cells leading to the activation of AKT and RPS6KA2.

artículo científico publicado en 2008

ERα-dependent E2F transcription can mediate resistance to estrogen deprivation in human breast cancer

artículo científico publicado en 2011

Early Adaptation and Acquired Resistance to CDK4/6 Inhibition in Estrogen Receptor-Positive Breast Cancer

artículo científico publicado en 2016

Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 10-year analysis of the ATAC trial

artículo científico publicado en 2010

Effect of body mass index on recurrences in tamoxifen and anastrozole treated women: an exploratory analysis from the ATAC trial

artículo científico publicado en 2010

Effect of tibolone on breast cancer cell proliferation in postmenopausal ER+ patients: results from STEM trial

artículo científico publicado en 2007

Effectiveness and molecular interactions of the clinically active mTORC1 inhibitor everolimus in combination with tamoxifen or letrozole in vitro and in vivo ⬇️

artículo científico publicado el 17 de octubre de 2012

Effects of Estrogen Receptor and Human Epidermal Growth Factor Receptor-2 Levels on the Efficacy of Trastuzumab: A Secondary Analysis of the HERA Trial

artículo científico

Effects of Vaginal Estrogens on Serum Estradiol Levels in Postmenopausal Breast Cancer Survivors and Women at Risk of Breast Cancer Taking an Aromatase Inhibitor or a Selective Estrogen Receptor Modulator ⬇️

artículo científico publicado el 7 de febrero de 2012

Effects of cyclin D1 gene amplification and protein expression on time to recurrence in postmenopausal breast cancer patients treated with anastrozole or tamoxifen: a TransATAC study

artículo científico publicado en 2012

Effects of the aromatase inhibitor letrozole on normal breast epithelial cell proliferation and metabolic indices in postmenopausal women: a pilot study for breast cancer prevention.

artículo científico publicado en 2002

Efforts to link biological and clinical breast cancer research

artículo científico publicado en 2003

Elevated ERK1/ERK2/estrogen receptor cross-talk enhances estrogen-mediated signaling during long-term estrogen deprivation

artículo científico publicado en 2005

Emerging biomarkers and new understanding of traditional markers in personalized therapy for breast cancer

scientific article published on December 2008

Emerging technologies for assessing HER2 amplification

artículo científico publicado en 2009

Endocrine effects of aromatase inhibitors

artículo científico publicado en 2010

Endocrinology and hormone therapy in breast cancer: aromatase inhibitors versus antioestrogens

artículo científico publicado en 2004

Endogenous sex hormones, breast cancer risk, and tamoxifen response: an ancillary study in the NSABP Breast Cancer Prevention Trial (P-1).

artículo científico publicado en 2006

Endogenous steroid hormone concentrations and risk of breast cancer among premenopausal women

artículo científico publicado en 2006

Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European prospective investigation into cancer in Norfolk (EPIC-Norfolk) Prospective Population Study

artículo científico publicado en 2007

Enhanced estrogen receptor (ER) alpha, ERBB2, and MAPK signal transduction pathways operate during the adaptation of MCF-7 cells to long term estrogen deprivation

artículo científico publicado en 2003

Enhancing endocrine response with novel targeted therapies: why have the clinical trials to date failed to deliver on the preclinical promise?

artículo científico publicado en 2008

Estrogen receptor: a never ending story?

artículo científico publicado en 2011

Evaluation of Ki-67 proliferation and apoptotic index before, during and after neoadjuvant chemotherapy for primary breast cancer

artículo científico publicado en 2006

Evaluation of Phi29-based whole-genome amplification for microarray-based comparative genomic hybridisation

artículo científico publicado en 2007

Exploring breast cancer estrogen disposition: the basis for endocrine manipulation

artículo científico publicado en 2011

Expression of key oestrogen-regulated genes differs substantially across the menstrual cycle in oestrogen receptor-positive primary breast cancer ⬇️

artículo científico publicado el 3 de febrero de 2013

Extreme loss of immunoreactive p-Akt and p-Erk1/2 during routine fixation of primary breast cancer ⬇️

artículo científico publicado el 28 de septiembre de 2010

Factors predicting late recurrence for estrogen receptor-positive breast cancer

scientific article published on 12 September 2013

Familial correlations in postmenopausal serum concentrations of sex steroid hormones and other mitogens: a twins and sisters study

artículo científico publicado en 2009

Feasibility of using tissue microarray cores of paraffin-embedded breast cancer tissue for measurement of gene expression: a proof-of-concept study

artículo científico publicado en 2010

Fulvestrant plus anastrozole or placebo versus exemestane alone after progression on non-steroidal aromatase inhibitors in postmenopausal patients with hormone-receptor-positive locally advanced or metastatic breast cancer (SoFEA): a composite, mult

artículo científico publicado en 2013

GDNF-RET signaling in ER-positive breast cancers is a key determinant of response and resistance to aromatase inhibitors

artículo científico publicado en 2013

Gene expression modules in primary breast cancers as risk factors for organotropic patterns of first metastatic spread: a case control study

artículo científico publicado en 2017

Gene expression patterns for doxorubicin (Adriamycin) and cyclophosphamide (cytoxan) (AC) response and resistance

artículo científico publicado en 2006

Gene expression profiles derived from fine needle aspiration correlate with response to systemic chemotherapy in breast cancer

artículo científico publicado en 2002

Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study

artículo científico publicado en 2014

Genome-wide association study of circulating estradiol, testosterone, and sex hormone-binding globulin in postmenopausal women

artículo científico publicado en 2012

Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines

artículo científico publicado en 2008

HER2 in situ hybridization in breast cancer: clinical implications of polysomy 17 and genetic heterogeneity ⬇️

artículo científico publicado el 28 de junio de 2013

HER2 testing in the UK: consensus from a national consultation

artículo científico publicado en 2007

Heterogeneity in global gene expression profiles between biopsy specimens taken peri-surgically from primary ER-positive breast carcinomas

artículo científico publicado en 2016

High-throughput automated scoring of Ki67 in breast cancer tissue microarrays from the Breast Cancer Association Consortium

artículo científico publicado en 2016

Human epidermal growth factor receptor 2 status correlates with lymph node involvement in patients with estrogen receptor (ER) negative, but with grade in those with ER-positive early-stage breast cancer suitable for cytotoxic chemotherapy

artículo científico publicado en 2007

Human epidermal growth factor receptor-2 and hormonal therapies: clinical implications.

artículo científico publicado en 2003

Identification of common variants in the SHBG gene affecting sex hormone-binding globulin levels and breast cancer risk in postmenopausal women

artículo científico publicado en 2008

Immunohistochemical Phenotype of Breast Cancer during 25-Year Follow-up of the Royal Marsden Tamoxifen Prevention Trial

artículo científico publicado en 2017

Impact of a Panel of 88 Single Nucleotide Polymorphisms on the Risk of Breast Cancer in High-Risk Women: Results From Two Randomized Tamoxifen Prevention Trials

artículo científico publicado en 2016

Impact of aromatase inhibitor treatment on global gene expression and its association with antiproliferative response in ER+ breast cancer in postmenopausal patients

scientific article published on 31 December 2019

Impact of estrogen deprivation on gene expression profiles of normal postmenopausal breast tissue in vivo

artículo científico publicado en 2008

Impact of mutational profiles on response of primary oestrogen receptor-positive breast cancers to oestrogen deprivation

artículo científico publicado en 2016

Impact of type of full-field digital image on mammographic density assessment and breast cancer risk estimation: a case-control study

artículo científico publicado en 2016

Implications of Gene-Environment Interaction in Studies of Gene Variants in Breast Cancer: An Example of Dietary Isoflavones and the D356N Polymorphism in theSex Hormone-Binding GlobulinGene: Figure 1

article

In Reply

Incomplete Estrogen Suppression With Gonadotropin-Releasing Hormone Agonists May Reduce Clinical Efficacy in Premenopausal Women With Early Breast Cancer

scientific article published on 04 January 2016

Influence of letrozole and anastrozole on total body aromatization and plasma estrogen levels in postmenopausal breast cancer patients evaluated in a randomized, cross-over study

artículo científico publicado en 2002

Influence of sex hormones on cancer progression

artículo científico publicado en 2010

Influences on circulating oestrogens in postmenopausal women: relationship with breast cancer

artículo científico publicado en 2006

Integration of Clinical Variables for the Prediction of Late Distant Recurrence in Patients With Estrogen Receptor-Positive Breast Cancer Treated With 5 Years of Endocrine Therapy: CTS5

Integration of signal transduction inhibitors with endocrine therapy: an approach to overcoming hormone resistance in breast cancer

artículo científico publicado en 2003

Integrative analyses identify modulators of response to neoadjuvant aromatase inhibitors in patients with early breast cancer

artículo científico publicado en 2015

International Web-based consultation on priorities for translational breast cancer research

artículo científico publicado en 2007

International expert consensus on primary systemic therapy in the management of early breast cancer: highlights of the Fourth Symposium on Primary Systemic Therapy in the Management of Operable Breast Cancer, Cremona, Italy (2010).

artículo científico

Interpreting plasma estrogen levels in breast cancer: caution needed

artículo científico

Intratumoral estrogen disposition in breast cancer

artículo científico publicado en 2010

Intrinsic Subgroups or Individual Biomarkers for Predicting Outcome of Metastatic Breast Cancer?

artículo científico publicado en 2016

Introduction to sessions on 'Predicting personal risk for breast cancer'

artículo científico publicado en 2008

Introduction to sessions on Personalising treatment

artículo científico publicado en 2007

Lapatinib restores hormone sensitivity with differential effects on estrogen receptor signaling in cell models of human epidermal growth factor receptor 2-negative breast cancer with acquired endocrine resistance

artículo científico publicado en 2010

Letrozole suppresses plasma estradiol and estrone sulphate more completely than anastrozole in postmenopausal women with breast cancer

artículo científico publicado en 2008

Life following aromatase inhibitors--where now for endocrine sequencing?

artículo científico publicado en 2005

Measurement of proliferation marker Ki67 in breast tumour FNAs using laser scanning cytometry in comparison to conventional immunocytochemistry ⬇️

artículo científico publicado el 1 de noviembre de 2003

Mechanisms of disease: angiogenesis and the management of breast cancer

artículo científico publicado en 2007

Mechanisms of resistance to aromatase inhibitors

artículo científico publicado en 2005

Mechanisms of tamoxifen resistance

artículo científico publicado en 2004

Menstrual cycle associated changes in hormone-related gene expression in oestrogen receptor positive breast cancer

artículo científico publicado en 2019

Menstrual cycle characteristics and steroid hormone, prolactin, and growth factor levels in premenopausal women

artículo científico publicado en 2017

Meta-analysis of breast cancer outcomes in adjuvant trials of aromatase inhibitors versus tamoxifen

artículo científico publicado en 2009

Microarray-based class discovery for molecular classification of breast cancer: analysis of interobserver agreement

artículo científico publicado en 2011

Microenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology-Genomic Integration Analysis

artículo científico publicado en 2016

Molecular Drivers of Oncotype DX, Prosigna, EndoPredict, and the Breast Cancer Index: A TransATAC Study

artículo científico publicado en 2020

Molecular changes associated with the acquisition of oestrogen hypersensitivity in MCF-7 breast cancer cells on long-term oestrogen deprivation

artículo científico publicado en 2002

Molecular changes in premenopausal oestrogen receptor-positive primary breast cancer in Vietnamese women after oophorectomy

artículo científico publicado en 2017

Molecular changes in tamoxifen-resistant breast cancer: relationship between estrogen receptor, HER-2, and p38 mitogen-activated protein kinase

artículo científico publicado en 2005

Molecular response to aromatase inhibitor treatment in primary breast cancer

artículo científico publicado en 2007

Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer

artículo científico publicado en 2015

Neoadjuvant endocrine therapy: Patient selection, treatment duration and surrogate endpoints

scientific article published on 06 August 2015

Neoadjuvant treatment of postmenopausal breast cancer with anastrozole, tamoxifen, or both in combination: the Immediate Preoperative Anastrozole, Tamoxifen, or Combined with Tamoxifen (IMPACT) multicenter double-blind randomized trial

artículo científico publicado en 2005

New and translational perspectives of oestrogen deprivation in breast cancer

artículo científico publicado en 2011

New biology of the oestrogen receptor

scientific article published on 01 July 2003

Non-existence of caveolin-1 gene mutations in human breast cancer

artículo científico publicado en 2011

Novel concepts for the chemoprevention of breast cancer through aromatase inhibition

artículo científico publicado en 2006

Optimizing the implementation of future treatment using surrogate end-points

artículo científico publicado en 2008

Origin and characteristics of adverse events in aromatase inhibition therapy for breast cancer ⬇️

artículo científico publicado el 1 de agosto de 2003

Outcome prediction for estrogen receptor-positive breast cancer based on postneoadjuvant endocrine therapy tumor characteristics

artículo científico publicado en 2008

Ovarian protection with goserelin during adjuvant chemotherapy for pre-menopausal women with early breast cancer (EBC).

artículo científico publicado en 2007

Paracrine-stimulated gene expression profile favors estradiol production in breast tumors

artículo científico publicado en 2006

Past oral contraceptive and hormone therapy use and endogenous hormone concentrations in postmenopausal women

article

Phase II study of the efficacy and tolerability of two dosing regimens of the farnesyl transferase inhibitor, R115777, in advanced breast cancer

artículo científico publicado en 2003

Phosphorylation of AKT pathway proteins is not predictive of benefit of taxane therapy in early breast cancer

artículo científico

Physical activity and inactivity in relation to sex hormone, prolactin, and insulin-like growth factor concentrations in premenopausal women - exercise and premenopausal hormones

scientific article published on 05 June 2007

Phytoestrogen concentrations in serum and spot urine as biomarkers for dietary phytoestrogen intake and their relation to breast cancer risk in European prospective investigation of cancer and nutrition-norfolk.

artículo científico publicado en 2004

Phytoestrogen exposure correlation with plasma estradiol in postmenopausal women in European Prospective Investigation of Cancer and Nutrition-Norfolk may involve diet-gene interactions.

artículo científico publicado en 2005

Plasma ESR1 Mutations and the Treatment of Estrogen Receptor-Positive Advanced Breast Cancer.

artículo científico

Polymorphisms associated with circulating sex hormone levels in postmenopausal women

artículo científico publicado en 2004

Polymorphisms in the CYP19 gene may affect the positive correlations between serum and urine phytoestrogen metabolites and plasma androgen concentrations in men

article

Polymorphisms of CYP19A1 and response to aromatase inhibitors in metastatic breast cancer patients

artículo científico

Pre-surgical study of the biological effects of the selective cyclo-oxygenase-2 inhibitor celecoxib in patients with primary breast cancer

artículo científico publicado en 2010

Predicting response to cytotoxic drugs – the endocrine part of the story ⬇️

artículo científico publicado el 1 de octubre de 2011

Prediction of risk of distant recurrence using the 21-gene recurrence score in node-negative and node-positive postmenopausal patients with breast cancer treated with anastrozole or tamoxifen: a TransATAC study

artículo científico publicado en 2010

Predictive algorithms for adjuvant therapy: TransATAC.

artículo científico publicado en 2011

Predictive and prognostic factors ⬇️

artículo científico publicado el 20 de diciembre de 2010

Preoperative models to evaluate endocrine strategies for breast cancer

artículo científico publicado en 2003

Proceedings of the Fifth International Conference on Recent Advances and Future Directions in Endocrine Therapy for Breast Cancer: conference summary statement

artículo científico publicado en 2006

Progesterone receptor A predominance is a discriminator of benefit from endocrine therapy in the ATAC trial

artículo científico

Prognostic value of a combined estrogen receptor, progesterone receptor, Ki-67, and human epidermal growth factor receptor 2 immunohistochemical score and comparison with the Genomic Health recurrence score in early breast cancer

artículo científico publicado en 2011

Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups

artículo científico publicado en 2016

Proliferation and apoptosis as markers of benefit in neoadjuvant endocrine therapy of breast cancer

artículo científico publicado en 2006

Proliferation marker Ki-67 in early breast cancer

artículo científico publicado en 2005

RAZOR: A Phase II Open Randomized Trial of Screening Plus Goserelin and Raloxifene Versus Screening Alone in Premenopausal Women at Increased Risk of Breast Cancer

artículo científico publicado en 2017

Recent data on intratumor estrogens in breast cancer

artículo científico publicado en 2011

Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update

artículo científico publicado en 2013

Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update

article

Red-clover-derived isoflavones and mammographic breast density: a double-blind, randomized, placebo-controlled trial [ISRCTN42940165]

artículo científico publicado en 2004

Reduced progesterone levels explain the reduced risk of breast cancer in obese premenopausal women: a new hypothesis

artículo científico publicado en 2014

Reduction in angiogenesis after neoadjuvant chemoendocrine therapy in patients with operable breast carcinoma

artículo científico publicado en 1999

Relationship between plasma estradiol levels and estrogen-responsive gene expression in estrogen receptor-positive breast cancer in postmenopausal women

artículo científico publicado en 2010

Relationship between quantitative estrogen and progesterone receptor expression and human epidermal growth factor receptor 2 (HER-2) status with recurrence in the Arimidex, Tamoxifen, Alone or in Combination trial

artículo científico publicado en 2008

Relationship of PIK3CA mutation and pathway activity with antiproliferative response to aromatase inhibition

artículo científico publicado en 2014

Relationship of ZNF423 and CTSO with breast cancer risk in two randomised tamoxifen prevention trials.

artículo científico publicado en 2016

Relationship of body mass index with aromatisation and plasma and tissue oestrogen levels in postmenopausal breast cancer patients treated with aromatase inhibitors

artículo científico publicado en 2014

Reply to E.A. Rakha et al.

artículo científico publicado en 2015

Reply to R. Bhargava et al and K. Lambein et al.

artículo científico publicado en 2014

Retrospective analysis of molecular scores for the prediction of distant recurrence according to baseline risk factors.

artículo científico publicado en 2016

Retrospective analysis of time to recurrence in the ATAC trial according to hormone receptor status: an hypothesis-generating study

artículo científico publicado en 2005

Revisiting the technical validation of tumour biomarker assays: how to open a Pandora's box ⬇️

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Risk of Recurrence and Chemotherapy Benefit for Patients With Node-Negative, Estrogen Receptor–Positive Breast Cancer: Recurrence Score Alone and Integrated With Pathologic and Clinical Factors ⬇️

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Risk of recurrence estimates with IHC4+C are tolerant of variations in staining and scoring: an analytical validity study

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Role of biologic markers in patient selection and application to disease prevention

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Second International Conference on Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer: summary consensus statement.

artículo científico publicado en 2003

Selection of REFERENCE genes for normalization of qRT-PCR data derived from FFPE breast tumors

artículo científico publicado en 2009

Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer

artículo científico publicado en 2009

Selective oestrogen receptor modulators in prevention of breast cancer: an updated meta-analysis of individual participant data

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Sex hormones and breast cancer risk and prognosis

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Sex steroids, growth factors and mammographic density: a cross-sectional study of UK postmenopausal Caucasian and Afro-Caribbean women

scientific article published on 22 June 2009

Short-term changes in Ki-67 during neoadjuvant treatment of primary breast cancer with anastrozole or tamoxifen alone or combined correlate with recurrence-free survival

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Short-term presurgical treatment for all?

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Src Is a Potential Therapeutic Target in Endocrine-Resistant Breast Cancer Exhibiting Low Estrogen Receptor-Mediated Transactivation

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Standardization of HER2 testing: results of an international proficiency-testing ring study

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Synergistic activity of letrozole and sorafenib on breast cancer cells

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Tamoxifen may prevent both ER+ and ER- breast cancers and select for ER- carcinogenesis: an alternative hypothesis

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Testosterone, SHBG and differential white blood cell count in middle-aged and older men.

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The association of plasma DHEA and DHEA sulfate with breast cancer risk in predominantly premenopausal women

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The biology of steroid hormones and endocrine treatment of breast cancer

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The effect of the stromal component of breast tumours on prediction of clinical outcome using gene expression microarray analysis

artículo científico publicado en 2006

The effects of neoadjuvant anastrozole and tamoxifen on circulating vascular endothelial growth factor and soluble vascular endothelial growth factor receptor 1 in breast cancer

artículo científico publicado en 2008

The effects of phytoestrogen isoflavones on bone density in women: a double-blind, randomized, placebo-controlled trial

artículo científico publicado en 2004

The farnesyltransferase inhibitor R115777 (tipifarnib) in combination with tamoxifen acts synergistically to inhibit MCF-7 breast cancer cell proliferation and cell cycle progression in vitro and in vivo

artículo científico publicado en 2007

The feasibility of using fine needle aspiration from primary breast cancers for cDNA microarray analyses

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The potential of new technologies/approaches. Introduction to Sessions 3 and 4.

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The prognostic effects of somatic mutations in ER-positive breast cancer

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The relationship between factors affecting endogenous oestradiol levels in postmenopausal women and breast cancer

artículo científico publicado en 2006

The role of caveolin-1 in human breast cancer ⬇️

artículo científico publicado el 8 de septiembre de 2011

The vascular endothelial growth factor receptor inhibitor PTK787/ZK222584 inhibits aromatase

artículo científico publicado en 2009

Total body aromatization in postmenopausal breast cancer patients is strongly correlated to plasma leptin levels

artículo científico publicado en 2007

Transient over-expression of estrogen receptor-α in breast cancer cells promotes cell survival and estrogen-independent growth

artículo científico publicado en 2010

Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer

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Trastuzumab-associated cardiac events at 8 years of median follow-up in the Herceptin Adjuvant trial (BIG 1-01).

artículo científico publicado en 2014

Treatment with high-dose estrogen (diethylstilbestrol) significantly decreases plasma estrogen and androgen levels but does not influence in vivo aromatization in postmenopausal breast cancer patients

artículo científico publicado en 2005

Triple negative breast cancer: molecular profiling and prognostic impact in adjuvant anthracycline-treated patients

artículo científico publicado en 2007

Tumour kinome re-wiring governs resistance to palbociclib in oestrogen receptor positive breast cancers, highlighting new therapeutic modalities

artículo científico publicado en 2020

Urinary 6-sulfatoxymelatonin levels and their correlations with lifestyle factors and steroid hormone levels

artículo científico publicado en 2006

Value and limitations of measuring HER-2 extracellular domain in the serum of breast cancer patients

scientific article published on 02 March 2009

Weight change associated with anastrozole and tamoxifen treatment in postmenopausal women with or at high risk of developing breast cancer

artículo científico publicado en 2012

Who would have thought a single Ki67 measurement would predict long-term outcome?

artículo científico publicado en 2009

miR-155 Drives Metabolic Reprogramming of ER+ Breast Cancer Cells Following Long-Term Estrogen Deprivation and Predicts Clinical Response to Aromatase Inhibitors

artículo científico publicado en 2016

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