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Lista de obras de Cynthia E. Dunbar

'Ghostbusting' at blood

artículo científico publicado en 2009

5-Azacytidine treatment in a beta (0)-thalassaemic patient unable to be transfused due to multiple alloantibodies

scientific article published on 01 July 1989

A new direction for gene therapy: intrathymic T cell-specific lentiviral gene transfer.

artículo científico publicado en 2005

A pilot study of nonmyeloablative allogeneic hematopoietic stem cell transplant for advanced systemic mastocytosis

scientific article published on 01 February 2006

AMD3100 mobilizes hematopoietic stem cells with long-term repopulating capacity in nonhuman primates.

artículo científico publicado en 2006

Abrogation of TGF-beta activity during retroviral transduction improves murine hematopoietic progenitor and repopulating cell gene transfer efficiency.

artículo científico publicado en 1998

Absence of donor-derived keratinocyte stem cells in skin tissues cultured from patients after mobilized peripheral blood hematopoietic stem cell transplantation

artículo científico publicado en 2002

Acquired somatic mutations in PNH reveal long-term maintenance of adaptive NK cells independent of HSPCs.

artículo científico publicado en 2016

Active thrombopoiesis is associated with worse severity and activity of chronic GVHD.

artículo científico publicado en 2013

Acute myeloid leukemia is associated with retroviral gene transfer to hematopoietic progenitor cells in a rhesus macaque

artículo científico publicado en 2006

Adaptive NK cells can persist in patients with GATA2 mutation depleted of stem and progenitor cells

artículo científico publicado en 2017

Amendment to Clinical Research Project. Project 90-C-195. April 1, 1993. Treatment of severe combined immunodeficiency disease (SCID) due to adenosine deaminase deficiency with autologous lymphocytes transduced with a human ADA gene.

artículo científico publicado en 1999

Amendment to clinical research projects. Genetic marking with retroviral vectors to study the feasibility of stem cell gene transfer and the biology of hematopoietic reconstitution after autologous transplantation in multiple myeloma, chronic myelog

scientific article published on 01 April 1993

American Society of Gene Therapy (ASGT) ad hoc subcommittee on retroviral-mediated gene transfer to hematopoietic stem cells

artículo científico publicado en 2003

An AAVS1-targeted minigene platform for correction of iPSCs from all five types of chronic granulomatous disease

artículo científico publicado en 2014

An educational infusion: more synergy between Blood and the American Society of Hematology ⬇️

artículo científico publicado el 29 de noviembre de 2012

Analysis of origin and optimization of expansion and transduction of circulating peripheral blood endothelial progenitor cells in the rhesus macaque model.

artículo científico publicado en 2002

Angioedema in patients treated with sirolimus and ACE inhibitor post hematopoietic SCT

artículo científico publicado en 2014

Anti-interleukin-2 receptor antibody (daclizumab) treatment of corticosteroid-refractory autoimmune thrombocytopenic purpura

scientific article published on 01 February 2006

Antibody-mediated cell labeling of peripheral T cells with micron-sized iron oxide particles (MPIOs) allows single cell detection by MRI

artículo científico publicado en 2007

Antithymocyte globulin for treatment of the bone marrow failure associated with myelodysplastic syndromes

artículo científico publicado en 2002

Assessing the risks of genotoxicity in the therapeutic development of induced pluripotent stem cells

artículo científico publicado en 2012

Assessment of rapid remobilization intervals with G-CSF and SCF in murine and rhesus macaque models

artículo científico publicado en 2001

Avoidance of stimulation improves engraftment of cultured and retrovirally transduced hematopoietic cells in primates

artículo científico publicado en 2001

BCL2A1a over-expression in murine hematopoietic stem and progenitor cells decreases apoptosis and results in hematopoietic transformation

artículo científico publicado en 2012

BM-derived cell therapies for cardiovascular disease.

artículo científico publicado en 2007

Blood's 70th anniversary: CARs on the Blood highway.

artículo científico publicado en 2016

Bone marrow homing and engraftment of human hematopoietic stem and progenitor cells is mediated by a polarized membrane domain ⬇️

artículo científico publicado el 6 de enero de 2012

Bone marrow skeletal stem/progenitor cell defects in dyskeratosis congenita and telomere biology disorders.

artículo científico publicado en 2014

CD34+ cell dose predicts relapse and survival after T-cell-depleted HLA-identical haematopoietic stem cell transplantation (HSCT) for haematological malignancies

scientific article published on 01 February 2000

CD34+ cell dose predicts survival, posttransplant morbidity, and rate of hematologic recovery after allogeneic marrow transplants for hematologic malignancies

artículo científico publicado en 1996

CD9 up-regulation on CD34+ cells with ingenol 3,20-dibenzoate does not improve homing in NSG mice ⬇️

artículo científico publicado el 26 de mayo de 2011

COOH-terminal-modified interleukin-3 is retained intracellularly and stimulates autocrine growth.

artículo científico

CRISPR/Cas9 PIG -A gene editing in nonhuman primate model demonstrates no intrinsic clonal expansion of PNH HSPCs

artículo científico publicado en 2019

CRISPR/Cas9-Based Safe-Harbor Gene Editing in Rhesus iPSCs

artículo científico publicado en 2017

CRISPR/Cas9-mediated introduction of the sodium/iodide symporter gene enables noninvasive in vivo tracking of induced pluripotent stem cell-derived cardiomyocytes

scientific article published on 23 July 2020

Challenges in vector and trial design using retroviral vectors for long-term gene correction in hematopoietic stem cell gene therapy

artículo científico publicado en 2012

Clonal tracking of haematopoietic cells: insights and clinical implications

artículo científico publicado en 2020

Clonal tracking of rhesus macaque hematopoiesis highlights a distinct lineage origin for natural killer cells

artículo científico publicado en 2014

Collection of hematopoietic stem cells from patients with autoimmune diseases.

artículo científico publicado en 2001

Combination therapy with rFVIIa and platelets for hemorrhage in patients with severe thrombocytopenia and alloimmunization

scientific article published on 01 March 2006

Contributions of gene marking to cell and gene therapies.

artículo científico publicado en 2011

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

artículo científico publicado en 2006

Correction of the disease phenotype in canine leukocyte adhesion deficiency using ex vivo hematopoietic stem cell gene therapy.

artículo científico publicado en 2006

Cyclosporine is required to prevent severe acute GVHD following T-cell-depleted peripheral blood stem cell transplantation

artículo científico publicado en 2003

Defective telomere elongation and hematopoiesis from telomerase-mutant aplastic anemia iPSCs

artículo científico publicado en 2013

Development of an inducible caspase-9 safety switch for pluripotent stem cell-based therapies

artículo científico publicado en 2014

Differences in the phenotype, cytokine gene expression profiles, and in vivo alloreactivity of T cells mobilized with plerixafor compared with G-CSF.

artículo científico publicado en 2013

Direct comparison of RD114-pseudotyped versus amphotropic-pseudotyped retroviral vectors for transduction of rhesus macaque long-term repopulating cells

artículo científico publicado en 2003

Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells

artículo científico publicado en 2004

Donor demographic and laboratory predictors of allogeneic peripheral blood stem cell mobilization in an ethnically diverse population

artículo científico publicado en 2008

Dynamic clonal analysis of murine hematopoietic stem and progenitor cells marked by 5 fluorescent proteins using confocal and multiphoton microscopy ⬇️

artículo científico publicado el 20 de septiembre de 2012

Dynamics of HSPC repopulation in nonhuman primates revealed by a decade-long clonal-tracking study

artículo científico publicado en 2014

Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice.

artículo científico publicado en 1990

Early reactivation of cytomegalovirus and high risk of interstitial pneumonitis following T-depleted BMT for adults with hematological malignancies

scientific article published on 01 August 1996

Effect of chronic cytokine therapy on clonal dynamics in nonhuman primates

artículo científico publicado en 2004

Efficient characterization of retro-, lenti-, and foamyvector-transduced cell populations by high-accuracy insertion site sequencing.

artículo científico publicado en 2003

Eltrombopag Added to Standard Immunosuppression for Aplastic Anemia.

artículo científico publicado en 2017

Eltrombopag and Improved Hematopoiesis in Refractory Aplastic Anemia ⬇️

artículo científico publicado el 5 de julio de 2012

Eltrombopag in aplastic anemia

artículo científico publicado en 2015

Eltrombopag maintains human hematopoietic stem and progenitor cells under inflammatory conditions mediated by IFN-γ

scientific article published on 25 February 2019

Eltrombopag restores trilineage hematopoiesis in refractory severe aplastic anemia that can be sustained on discontinuation of drug.

artículo científico publicado en 2013

Evaluation of a rapamycin-regulated serotype 2 adeno-associated viral vector in macaque parotid glands

artículo científico publicado en 2010

Ex vivo expansion of genetically marked rhesus peripheral blood progenitor cells results in diminished long-term repopulating ability ⬇️

artículo científico publicado el 15 de agosto de 1998

Ex vivo expansion of retrovirally transduced primate CD34+ cells results in overrepresentation of clones with MDS1/EVI1 insertion sites in the myeloid lineage after transplantation.

artículo científico publicado en 2010

Expression of interferon-gamma by stromal cells inhibits murine long-term repopulating hematopoietic stem cell activity

artículo científico publicado en 1999

Feline leukemia virus integrase and capsid packaging functions do not change the insertion profile of standard Moloney retroviral vectors

artículo científico publicado en 2010

Functional Niche Competition Between Normal Hematopoietic Stem and Progenitor Cells and Myeloid Leukemia Cells

artículo científico publicado en 2015

Gene Editing of Human Hematopoietic Stem and Progenitor Cells: Promise and Potential Hurdles.

artículo científico publicado en 2016

Gene and Cell Therapies in Expansion Mode: ASGCT 2016.

artículo científico publicado en 2016

Gene marking and gene therapy directed at primary hematopoietic cells.

artículo científico publicado en 1996

Gene therapy activates EVI1, destabilizes chromosomes.

artículo científico publicado en 2010

Gene therapy comes of age.

artículo científico publicado en 2018

Gene transfer into hematopoietic cells. Implications for cancer therapy

artículo científico publicado en 1994

Gene transfer into hematopoietic progenitor and stem cells: progress and problems.

artículo científico publicado en 1994

Gene transfer to hematopoietic stem cells: implications for gene therapy of human disease.

artículo científico publicado en 1996

Genetic marking as an approach to studying in vivo hematopoiesis: progress in the non-human primate model

artículo científico publicado en 2002

Genetically modified CD34+ hematopoietic stem cells contribute to turnover of brain perivascular macrophages in long-term repopulated primates.

artículo científico publicado en 2009

Genotoxicity of retroviral integration in hematopoietic cells.

artículo científico publicado en 2006

Geographic clonal tracking in macaques provides insights into HSPC migration and differentiation.

artículo científico publicado en 2017

Granulocyte colony-stimulating factor recruitment of CD34+ progenitors to peripheral blood: impaired mobilization in chronic granulomatous disease and adenosine deaminase--deficient severe combined immunodeficiency disease patients

artículo científico publicado en 1996

Green fluorescent protein retroviral vectors: low titer and high recombination frequency suggest a selective disadvantage.

artículo científico publicado en 1997

Growth factors and stromal support generate very efficient retroviral transduction of peripheral blood CD34+ cells from Gaucher patients

scientific article published on 01 July 1995

Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer ⬇️

artículo científico publicado el 1 de octubre de 1992

Hematopoietic stem cell engineering at a crossroads

artículo científico publicado en 2012

Hematopoietic stem cell gene therapy: dead or alive?

artículo científico publicado en 2005

Hematopoietic stem cell gene therapy:assessing the relevance of preclinical models

artículo científico publicado en 2013

Hematopoietic stem-cell behavior in nonhuman primates

artículo científico publicado en 2007

Hepatitis-associated aplastic anemia

artículo científico publicado en 1997

High efficiency restriction enzyme-free linear amplification-mediated polymerase chain reaction approach for tracking lentiviral integration sites does not abrogate retrieval bias.

artículo científico publicado en 2012

High incidence of adeno- and polyomavirus-induced hemorrhagic cystitis in bone marrow allotransplantation for hematological malignancy following T cell depletion and cyclosporine.

artículo científico publicado en 1998

High-dose cyclophosphamide in severe aplastic anaemia: a randomised trial

artículo científico publicado en 2000

High-dose cyclophosphamide with autologous lymphocyte-depleted peripheral blood stem cell (PBSC) support for treatment of refractory chronic autoimmune thrombocytopenia

artículo científico publicado en 2002

Highlights from the third annual ASGT meeting. American Society of Gene Therapy.

artículo científico publicado en 2000

Highly efficient endosomal labeling of progenitor and stem cells with large magnetic particles allows magnetic resonance imaging of single cells.

artículo científico publicado en 2003

Human and rhesus macaque hematopoietic stem cells cannot be purified based only on SLAM family markers

artículo científico publicado en 2010

Human gene marker/therapy clinical protocols

artículo científico publicado en 1996

Human gene marker/therapy clinical protocols

artículo científico publicado en 1996

Human gene marker/therapy clinical protocols

scientific article published on 01 December 1999

Human gene marker/therapy clinical protocols

scientific article published on 01 April 2000

Human gene marker/therapy clinical protocols

artículo científico publicado en 1997

Human hematopoietic stem cells from mobilized peripheral blood can be purified based on CD49f integrin expression

artículo científico publicado en 2015

Human thrombopoietin levels are high when thrombocytopenia is due to megakaryocyte deficiency and low when due to increased platelet destruction.

artículo científico publicado en 1996

IFN-γ regulates survival and function of tumor-induced CD11b+ Gr-1high myeloid derived suppressor cells by modulating the anti-apoptotic molecule Bcl2a1.

artículo científico publicado en 2014

Imatinib inhibits T-cell receptor-mediated T-cell proliferation and activation in a dose-dependent manner

artículo científico publicado en 2004

Improved Amphotropic Retrovirus‐Mediated Gene Transfer into Hematopoietic Stem Cells ⬇️

artículo científico publicado el 30 de junio de 1998

In vivo clonal tracking of hematopoietic stem and progenitor cells marked by five fluorescent proteins using confocal and multiphoton microscopy

artículo científico publicado en 2014

In vivo gene marking of rhesus macaque long-term repopulating hematopoietic cells using a VSV-G pseudotyped versus amphotropic oncoretroviral vector.

artículo científico publicado en 2004

In vivo marking of rhesus monkey lymphocytes by adeno-associated viral vectors: direct comparison with retroviral vectors.

artículo científico publicado en 1999

In vivo selection of hematopoietic progenitor cells and temozolomide dose intensification in rhesus macaques through lentiviral transduction with a drug resistance gene

artículo científico publicado en 2009

In vivo selective expansion of gene-modified hematopoietic cells in a nonhuman primate model.

artículo científico publicado en 2002

In-vivo tracking of adoptively transferred natural killer-cells in rhesus macaques using 89Zirconium-oxine cell labeling and PET imaging

artículo científico publicado en 2020

Insertion sites in engrafted cells cluster within a limited repertoire of genomic areas after gammaretroviral vector gene therapy

artículo científico publicado en 2011

Integration-specific In Vitro Evaluation of Lentivirally Transduced Rhesus CD34(+) Cells Correlates With In Vivo Vector Copy Number.

artículo científico publicado en 2013

Introducing "e-Blood"

scientific article published on 01 May 2009

Introduction of an activated RAS oncogene into murine bone marrow lymphoid progenitors via retroviral gene transfer results in thymic lymphomas.

artículo científico publicado en 1991

Isolation and identification of antifungal and antialgal alkaloids from Haplophyllum sieversii.

artículo científico publicado en 2005

Keeping up with Blood: introducing our CME program

scientific article published on 01 January 2010

Keratinocyte growth factor augments immune reconstitution after autologous hematopoietic progenitor cell transplantation in rhesus macaques

artículo científico publicado en 2007

Large granular lymphocytic proliferation-associated cyclic thrombocytopenia

artículo científico publicado en 2005

Long-term clinical and molecular follow-up of large animals receiving retrovirally transduced stem and progenitor cells: no progression to clonal hematopoiesis or leukemia

artículo científico publicado en 2004

Long-term culture of chronic myelogenous leukemia marrow cells on stem cell factor-deficient stroma favors benign progenitors

artículo científico publicado en 1995

Long-term in vivo expression of the human glucocerebrosidase gene in nonhuman primates after CD34+ hematopoietic cell transduction with cell-free retroviral vector preparations.

artículo científico publicado en 1995

Low-dose total body irradiation causes clonal fluctuation of primate hematopoietic stem and progenitor cells

artículo científico publicado en 2004

MRI detection of single particles for cellular imaging.

scholarly article

Maintenance of murine long-term repopulating stem cells in ex vivo culture is affected by modulation of transforming growth factor-beta but not macrophage inflammatory protein-1 alpha activities.

artículo científico publicado en 1996

Measurement of the absolute immature platelet number reflects marrow production and is not impacted by platelet transfusion

artículo científico publicado en 2012

Mobilization as a preparative regimen for hematopoietic stem cell transplantation

artículo científico publicado en 2006

Modeling Human Bone Marrow Failure Syndromes Using Pluripotent Stem Cells and Genome Engineering

artículo científico publicado en 2015

Molecular and serological examination of the relationship of human herpesvirus 8 to multiple myeloma: orf 26 sequences in bone marrow stroma are not restricted to myeloma patients and other regions of the genome are not detected.

artículo científico publicado en 1998

Molecular characterisation of side population cells with cancer stem cell-like characteristics in small-cell lung cancer.

artículo científico publicado en 2010

Molecular remission and reversal of myelofibrosis in response to imatinib mesylate treatment in patients with the myeloproliferative variant of hypereosinophilic syndrome

artículo científico publicado en 2004

More frequent Blood transfusions

artículo científico publicado en 2009

Multilineage involvement of the fusion gene in patients with FIP1L1/PDGFRA-positive hypereosinophilic syndrome

artículo científico publicado en 2006

Multiple myeloma. New approaches to therapy

artículo científico publicado en 1993

Murine Long-Term Repopulating Ability Is Compromised by Ex Vivo Culture in Serum-Free Medium Despite Preservation of Committed Progenitors ⬇️

artículo científico publicado el 1 de diciembre de 1997

Murine bone marrow expressing the neomycin resistance gene has no competitive disadvantage assessed in vivo

artículo científico publicado en 1998

No discrepancy between in vivo gene marking efficiency assessed in peripheral blood populations compared with bone marrow progenitors or CD34+ cells

scientific article published on 01 March 1999

No evidence for clonal selection due to lentiviral integration sites in human induced pluripotent stem cells.

artículo científico publicado en 2010

No evidence of clonal dominance in primates up to 4 years following transplantation of multidrug resistance 1 retrovirally transduced long-term repopulating cells

artículo científico publicado en 2007

No impact of lentiviral transduction on hematopoietic stem/progenitor cell telomere length or gene expression in the rhesus macaque model.

artículo científico publicado en 2013

Outcomes and risks of granulocyte colony-stimulating factor in patients with coronary artery disease.

artículo científico publicado en 2005

Path to the clinic: assessment of iPSC-based cell therapies in vivo in a nonhuman primate model

artículo científico publicado en 2014

Pathophysiology and management of thrombocytopenia in bone marrow failure: possible clinical applications of TPO receptor agonists in aplastic anemia and myelodysplastic syndromes ⬇️

artículo científico publicado el 21 de mayo de 2013

Patients with myeloid malignancies bearing PDGFRB fusion genes achieve durable long-term remissions with imatinib

artículo científico publicado en 2014

Patients, hematologists, and time

scientific article published on 01 March 2011

Persistence and expression of the adenosine deaminase gene for 12 years and immune reaction to gene transfer components: long-term results of the first clinical gene therapy trial.

artículo científico publicado en 2002

Persistent elevation of plasma thrombopoietin levels after treatment in severe aplastic anemia

artículo científico publicado en 2017

Pharmacological modulation of humoral immunity in a nonhuman primate model of AAV gene transfer for hemophilia B.

artículo científico publicado en 2012

Pilot study of high dose ICE (ifosfamide, carboplatin, etoposide) chemotherapy and autologous bone marrow transplant (ABMT) with neoR-transduced bone marrow and peripheral blood stem cells in patients with metastatic breast cancer

scientific article published on 01 June 1993

Polyclonal long-term repopulating stem cell clones in a primate model

artículo científico publicado en 2002

Positive selection of CD34+ hematopoietic cells using an immunoaffinity column results in T cell-depletion equivalent to elutriation

scientific article published on 01 April 1995

Prediction and prevention of transplant-related mortality from pulmonary causes after total body irradiation and allogeneic stem cell transplantation

scientific article published on 01 March 2005

Prolonged high-level detection of retrovirally marked hematopoietic cells in nonhuman primates after transduction of CD34+ progenitors using clinically feasible methods

scientific article published on 01 March 2000

Prolonged multilineage clonal hematopoiesis in a rhesus recipient of CD34 positive cells marked with a RD114 pseudotyped oncoretroviral vector.

artículo científico publicado en 2003

Quantitative stability of hematopoietic stem and progenitor cell clonal output in rhesus macaques receiving transplants.

artículo científico publicado en 2017

Rabaptin-5 is a novel fusion partner to platelet-derived growth factor beta receptor in chronic myelomonocytic leukemia.

artículo científico publicado en 2001

Recurrent retroviral vector integration at the Mds1/Evi1 locus in nonhuman primate hematopoietic cells ⬇️

artículo científico publicado en 2005

Regression of Metastatic Renal-Cell Carcinoma after Nonmyeloablative Allogeneic Peripheral-Blood Stem-Cell Transplantation

artículo científico publicado en 2000

Regulated apoptosis of genetically modified hematopoietic stem and progenitor cells via an inducible caspase-9 suicide gene in rhesus macaques.

artículo científico publicado en 2015

Relapse following discontinuation of imatinib mesylate therapy for FIP1L1/PDGFRA-positive chronic eosinophilic leukemia: implications for optimal dosing

artículo científico publicado en 2007

Retroviral gene transduction of adult peripheral blood or marrow-derived CD34+ cells for six hours without growth factors or on autologous stroma does not improve marking efficiency assessed in vivo

artículo científico publicado en 1997

Retroviral marking and transplantation of rhesus hematopoietic cells by nonmyeloablative conditioning.

artículo científico publicado en 1999

Retroviral mediated gene transfer of the Fanconi anemia complementation group C gene to hematopoietic progenitors of group C patients

artículo científico publicado en 1997

Retroviral mediated transfer of the cDNA for human glucocerebrosidase into hematopoietic stem cells of patients with Gaucher disease. A phase I study

artículo científico publicado en 1996

Retroviral mediated transfer of the human multidrug resistance gene (MDR-1) into hematopoietic stem cells during autologous transplantation after intensive chemotherapy for metastatic breast cancer

artículo científico publicado en 1994

Retroviral transduction efficiency of G-CSF+SCF-mobilized peripheral blood CD34+ cells is superior to G-CSF or G-CSF+Flt3-L-mobilized cells in nonhuman primates.

artículo científico publicado en 2002

Retroviral transduction of CD34-enriched hematopoietic progenitor cells under serum-free conditions

scientific article published on 01 January 1996

Retroviral-mediated gene transfer into CD34-enriched human peripheral blood stem cells.

artículo científico publicado en 1993

Retroviral-mediated transfer of interleukin-6 into hematopoietic cells of mice results in a syndrome resembling Castleman's disease

scientific article published on 01 January 1990

Retroviral-mediated transfer of the murine interleukin-3 gene engineered for intracellular retention results in a myeloproliferative syndrome but is associated with circulating interleukin-3 levels.

artículo científico publicado en 1993

Rhesus Macaque iPSC Generation and Maintenance

artículo científico publicado en 2017

Rhesus iPSC Safe Harbor Gene-Editing Platform for Stable Expression of Transgenes in Differentiated Cells of All Germ Layers.

artículo científico publicado en 2017

Separating the wheat from the chaff: selection of benign hematopoietic cells in chronic myeloid leukemia

artículo científico publicado en 1992

Serial cardiac magnetic resonance imaging of injected mesenchymal stem cells

artículo científico publicado en 2003

Sorting of transgenic secretory proteins in rhesus macaque parotid glands after adenovirus-mediated gene transfer.

artículo científico publicado en 2008

Stem and progenitor cell therapies: insights from non-human primate models.

artículo científico publicado en 2004

Stem cell gene therapy: the risks of insertional mutagenesis and approaches to minimize genotoxicity ⬇️

artículo científico publicado el 27 de diciembre de 2011

Sustained high-level polyclonal hematopoietic marking and transgene expression 4 years after autologous transplantation of rhesus macaques with SIV lentiviral vector-transduced CD34+ cells

scientific article published on April 2009

T cell-depleted bone marrow transplantation and delayed T cell add-back to control acute GVHD and conserve a graft-versus-leukemia effect

scientific article published on 01 March 1998

T cell-depleted granulocyte colony-stimulating factor (G-CSF) modified allogenic bone marrow transplantation for hematological malignancy improves graft CD34+ cell content but is associated with delayed pancytopenia

scientific article published on 01 March 1998

The Role of Nonhuman Primate Animal Models in the Clinical Development of Pluripotent Stem Cell Therapies.

artículo científico publicado en 2016

The effect of multidrug-resistance 1 gene versus neo transduction on ex vivo and in vivo expansion of rhesus macaque hematopoietic repopulating cells

artículo científico publicado en 2001

The impact of aging on primate hematopoiesis as interrogated by clonal tracking.

artículo científico publicado en 2018

The impact of ex vivo cytokine stimulation on engraftment of primitive hematopoietic cells in a non-human primate model.

artículo científico publicado en 2001

The impact of low-dose busulfan on clonal dynamics in nonhuman primates

artículo científico publicado en 2004

The presence of the carboxy-terminal fragment of fibronectin allows maintenance of non-human primate long-term hematopoietic repopulating cells during extended ex vivo culture and transduction.

artículo científico publicado en 2004

The use of nonhuman primate models to improve gene transfer into haematopoietic stem cells.

artículo científico publicado en 2001

Thrombopoietic status of patients on haemodialysis

artículo científico publicado en 2016

Thymidine Kinase Suicide Gene-mediated Ganciclovir Ablation of Autologous Gene-modified Rhesus Hematopoiesis ⬇️

artículo científico publicado el 21 de agosto de 2012

Transcriptome analysis reveals similarities between human blood CD3- CD56bright cells and mouse CD127+ innate lymphoid cells.

artículo científico publicado en 2017

Transduction of hematopoietic stem cells in humans and in nonhuman primates ⬇️

artículo científico publicado el 1 de enero de 1997

Transgenic mice expressing antisense interleukin-3 RNA develop a B-cell lymphoproliferative syndrome or neurologic dysfunction

artículo científico publicado en 1994

Transient in vivo selection of transduced peripheral blood cells using antifolate drug selection in rhesus macaques that received transplants with hematopoietic stem cells expressing dihydrofolate reductase vectors.

artículo científico publicado en 2003

Transient silencing of PTEN in human CD34+ cells enhances their proliferative potential and ability to engraft immunodeficient mice ⬇️

artículo científico publicado el 20 de octubre de 2011

Transplant dose of CD34(+) and CD3(+) cells predicts outcome in patients with haematological malignancies undergoing T cell-depleted peripheral blood stem cell transplants with delayed donor lymphocyte add-back

scientific article published on 01 October 2001

Treatment of Diamond-Blackfan anaemia with haematopoietic growth factors, granulocyte-macrophage colony stimulating factor and interleukin 3: sustained remissions following IL-3.

artículo científico publicado en 1991

Treatment of severe combined immunodeficiency disease (SCID) due to adenosine deaminase deficiency with CD34+ selected autologous peripheral blood cells transduced with a human ADA gene. Amendment to clinical research project, Project 90-C-195, Janu

scientific article published on 01 August 1993

Tumor-specific recognition of human myeloma cells by idiotype-induced CD8(+) T cells

scientific article published on 01 October 2000

Two Decades of ASGCT: Dreams Become Reality.

artículo científico publicado en 2017

Update on hematopoietic stem cell gene transfer using non-human primate models.

artículo científico publicado en 2002

Update on the use of nonhuman primate models for preclinical testing of gene therapy approaches targeting hematopoietic cells.

artículo científico publicado en 2001

Workshop on long-term follow-up of participants in human gene transfer research

artículo científico publicado en 2004

iPSCs and fibroblast subclones from the same fibroblast population contain comparable levels of sequence variations.

artículo científico publicado en 2017

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