Lista de obras - Pedro M Nieto - Dominio Público Uruguay

1,2-Mannobioside mimic: synthesis, DC-SIGN interaction by NMR and docking, and antiviral activity.

artículo científico publicado en 2007

3D structure of a heparin mimetic analogue of a FGF-1 activator. A NMR and molecular modelling study

scientific article published on 31 October 2013

A Non-damaging Method to Analyze the Configuration and Dynamics of Nitrotyrosines in Proteins

artículo científico publicado en 2012

A STD-NMR study of the interaction of the Anabaena ferredoxin-NADP+ reductase with the coenzyme

artículo científico publicado en 2014

A molecular dynamics description of the conformational flexibility of the L-iduronate ring in glycosaminoglycans.

artículo científico publicado en 2003

Backbone dynamics of a biologically active human FGF-1 monomer, complexed to a hexasaccharide heparin-analogue, by 15N NMR relaxation methods.

artículo científico

Chondroitin Sulfate Tetrasaccharides: Synthesis, Three-Dimensional Structure and Interaction with Midkine

artículo científico

Conformational flexibility of a synthetic glycosylaminoglycan bound to a fibroblast growth factor. FGF-1 recognizes both the (1)C(4) and (2)S(O) conformations of a bioactive heparin-like hexasaccharide.

artículo científico publicado en 2005

Conformational selection of the AGA*IA(M) heparin pentasaccharide when bound to the fibroblast growth factor receptor.

artículo científico publicado en 2011

Conformations of the iduronate ring in short heparin fragments described by time-averaged distance restrained molecular dynamics.

artículo científico publicado en 2013

Detection and quantitative analysis of two independent binding modes of a small ligand responsible for DC-SIGN clustering

artículo científico publicado en 2015

Docking, synthesis, and NMR studies of mannosyl trisaccharide ligands for DC-SIGN lectin.

artículo científico publicado en 2008

Dynamic properties of biologically active synthetic heparin-like hexasaccharides

artículo científico publicado en 2005

Effect of the substituents of the neighboring ring in the conformational equilibrium of iduronate in heparin-like trisaccharides

artículo científico publicado el 9 de noviembre de 2012

Experimental measurement of carbohydrate-aromatic stacking in water by using a dangling-ended DNA model system

artículo científico publicado en 2008

Fluorous-tag assisted synthesis of a glycosaminoglycan mimetic tetrasaccharide as a high-affinity FGF-2 and midkine ligand.

artículo científico publicado en 2018

Gender dimorphism and altitudinal variation of secondary compounds in leaves of the gynodioecious shrub Daphne laureola

artículo científico publicado en 2005

Glycodendrimers as Chondroitin Sulfate Mimetics: Synthesis and Binding to Growth Factor Midkine

artículo científico publicado en 2017

Glycodendritic structures based on Boltorn hyperbranched polymers and their interactions with Lens culinaris lectin.

artículo científico publicado en 2003

Importance of the polarity of the glycosaminoglycan chain on the interaction with FGF-1.

artículo científico

Improvement on binding of chondroitin sulfate derivatives to midkine by increasing hydrophobicity.

artículo científico publicado en 2016

Insights into molecular recognition of Lewis(X) mimics by DC-SIGN using NMR and molecular modelling

artículo científico publicado en 2011

Interactions between a Heparin Trisaccharide Library and FGF-1 Analyzed by NMR Methods

artículo científico publicado en 2017

Langerin-heparin interaction: two binding sites for small and large ligands as revealed by a combination of NMR spectroscopy and cross-linking mapping experiments.

artículo científico

Ligand-receptor binding affinities from saturation transfer difference (STD) NMR spectroscopy: the binding isotherm of STD initial growth rates

artículo científico publicado en 2010

Mimicking Tyrosine Phosphorylation in Human Cytochrome c by the Evolved tRNA Synthetase Technique

artículo científico publicado en 2015

Mutants of the Arabidopsis thaliana cation/H+ antiporter AtNHX1 conferring increased salt tolerance in yeast: the endosome/prevacuolar compartment is a target for salt toxicity.

artículo científico publicado en 2009

Nitration of tyrosine 74 prevents human cytochrome c to play a key role in apoptosis signaling by blocking caspase-9 activation.

artículo científico publicado en 2010

Rational-Differential Design of Highly Specific Glycomimetic Ligands: Targeting DC-SIGN and Excluding Langerin Recognition

artículo científico publicado en 2017

STD-NMR: application to transient interactions between biomolecules-a quantitative approach.

artículo científico publicado en 2011

Saturation transfer difference (STD) NMR spectroscopy characterization of dual binding mode of a mannose disaccharide to DC-SIGN.

artículo científico publicado en 2008

Solution NMR structure of a human FGF-1 monomer, activated by a hexasaccharide heparin-analogue.

artículo científico

Structure and dynamics of the conserved protein GPI anchor core inserted into detergent micelles

artículo científico publicado en 2006

Structure of a glycomimetic ligand in the carbohydrate recognition domain of C-type lectin DC-SIGN. Structural requirements for selectivity and ligand design

artículo científico publicado en 2013

Structures of glycans bound to receptors from saturation transfer difference (STD) NMR spectroscopy: quantitative analysis by using CORCEMA-ST

artículo científico publicado en 2015

Synthesis and structural study of two new heparin-like hexasaccharides

artículo científico publicado en 2003

Synthesis of (1→3) Thiodisaccharides of GlcNAc and the Serendipitous Formation of 2,3-Dideoxy-(1→2)-thiodisaccharides through a Vinyl Azide Intermediate

artículo científico publicado en 2019

Synthesis of a Fluorous-Tagged Hexasaccharide and Interaction with Growth Factors Using Sugar-Coated Microplates

artículo científico publicado en 2019

Synthesis of amine-functionalized heparin oligosaccharides for the investigation of carbohydrate–protein interactions in microtiter plates ⬇️

artículo científico publicado el 31 de enero de 2012

Synthesis of chondroitin/dermatan sulfate-like oligosaccharides and evaluation of their protein affinity by fluorescence polarization.

artículo científico

Synthesis of hyaluronic acid oligosaccharides and exploration of a fluorous-assisted approach

artículo científico publicado en 2014

Synthesis of novel DC-SIGN ligands with an alpha-fucosylamide anchor.

artículo científico publicado en 2008

Tachykinins and tachykinin receptors: structure and activity relationships

artículo científico publicado en 2004

The Use of NMR to Study Transient Carbohydrate-Protein Interactions

artículo científico publicado en 2018

The activation of fibroblast growth factors (FGFs) by glycosaminoglycans: influence of the sulfation pattern on the biological activity of FGF-1

artículo científico publicado en 2004

Unexpected loss of stereoselectivity in glycosylation reactions during the synthesis of chondroitin sulfate oligosaccharides

artículo científico publicado en 2019

Lista de obras de Pedro M Nieto

1,2-Mannobioside mimic: synthesis, DC-SIGN interaction by NMR and docking, and antiviral activity.

3D structure of a heparin mimetic analogue of a FGF-1 activator. A NMR and molecular modelling study

A Non-damaging Method to Analyze the Configuration and Dynamics of Nitrotyrosines in Proteins

A STD-NMR study of the interaction of the Anabaena ferredoxin-NADP+ reductase with the coenzyme

A molecular dynamics description of the conformational flexibility of the L-iduronate ring in glycosaminoglycans.

Backbone dynamics of a biologically active human FGF-1 monomer, complexed to a hexasaccharide heparin-analogue, by 15N NMR relaxation methods.

Chondroitin Sulfate Tetrasaccharides: Synthesis, Three-Dimensional Structure and Interaction with Midkine

Conformational flexibility of a synthetic glycosylaminoglycan bound to a fibroblast growth factor. FGF-1 recognizes both the (1)C(4) and (2)S(O) conformations of a bioactive heparin-like hexasaccharide.

Conformational selection of the AGA*IA(M) heparin pentasaccharide when bound to the fibroblast growth factor receptor.

Conformations of the iduronate ring in short heparin fragments described by time-averaged distance restrained molecular dynamics.

Detection and quantitative analysis of two independent binding modes of a small ligand responsible for DC-SIGN clustering

Docking, synthesis, and NMR studies of mannosyl trisaccharide ligands for DC-SIGN lectin.

Dynamic properties of biologically active synthetic heparin-like hexasaccharides

Effect of the substituents of the neighboring ring in the conformational equilibrium of iduronate in heparin-like trisaccharides

Experimental measurement of carbohydrate-aromatic stacking in water by using a dangling-ended DNA model system

Fluorous-tag assisted synthesis of a glycosaminoglycan mimetic tetrasaccharide as a high-affinity FGF-2 and midkine ligand.

Gender dimorphism and altitudinal variation of secondary compounds in leaves of the gynodioecious shrub Daphne laureola

Glycodendrimers as Chondroitin Sulfate Mimetics: Synthesis and Binding to Growth Factor Midkine

Glycodendritic structures based on Boltorn hyperbranched polymers and their interactions with Lens culinaris lectin.

Importance of the polarity of the glycosaminoglycan chain on the interaction with FGF-1.

Improvement on binding of chondroitin sulfate derivatives to midkine by increasing hydrophobicity.

Insights into molecular recognition of Lewis(X) mimics by DC-SIGN using NMR and molecular modelling

Interactions between a Heparin Trisaccharide Library and FGF-1 Analyzed by NMR Methods

Langerin-heparin interaction: two binding sites for small and large ligands as revealed by a combination of NMR spectroscopy and cross-linking mapping experiments.

Ligand-receptor binding affinities from saturation transfer difference (STD) NMR spectroscopy: the binding isotherm of STD initial growth rates

Mimicking Tyrosine Phosphorylation in Human Cytochrome c by the Evolved tRNA Synthetase Technique

Mutants of the Arabidopsis thaliana cation/H+ antiporter AtNHX1 conferring increased salt tolerance in yeast: the endosome/prevacuolar compartment is a target for salt toxicity.

Nitration of tyrosine 74 prevents human cytochrome c to play a key role in apoptosis signaling by blocking caspase-9 activation.

Rational-Differential Design of Highly Specific Glycomimetic Ligands: Targeting DC-SIGN and Excluding Langerin Recognition

STD-NMR: application to transient interactions between biomolecules-a quantitative approach.

Saturation transfer difference (STD) NMR spectroscopy characterization of dual binding mode of a mannose disaccharide to DC-SIGN.

Solution NMR structure of a human FGF-1 monomer, activated by a hexasaccharide heparin-analogue.

Structure and dynamics of the conserved protein GPI anchor core inserted into detergent micelles

Structure of a glycomimetic ligand in the carbohydrate recognition domain of C-type lectin DC-SIGN. Structural requirements for selectivity and ligand design

Structures of glycans bound to receptors from saturation transfer difference (STD) NMR spectroscopy: quantitative analysis by using CORCEMA-ST

Synthesis and structural study of two new heparin-like hexasaccharides

Synthesis of (1→3) Thiodisaccharides of GlcNAc and the Serendipitous Formation of 2,3-Dideoxy-(1→2)-thiodisaccharides through a Vinyl Azide Intermediate

Synthesis of a Fluorous-Tagged Hexasaccharide and Interaction with Growth Factors Using Sugar-Coated Microplates

Synthesis of amine-functionalized heparin oligosaccharides for the investigation of carbohydrate–protein interactions in microtiter plates ⬇️

Synthesis of chondroitin/dermatan sulfate-like oligosaccharides and evaluation of their protein affinity by fluorescence polarization.

Synthesis of hyaluronic acid oligosaccharides and exploration of a fluorous-assisted approach

Synthesis of novel DC-SIGN ligands with an alpha-fucosylamide anchor.

Tachykinins and tachykinin receptors: structure and activity relationships

The Use of NMR to Study Transient Carbohydrate-Protein Interactions

The activation of fibroblast growth factors (FGFs) by glycosaminoglycans: influence of the sulfation pattern on the biological activity of FGF-1

Unexpected loss of stereoselectivity in glycosylation reactions during the synthesis of chondroitin sulfate oligosaccharides