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Lista de obras de Hans H. Maurer

2,5-Dimethoxyamphetamine-derived designer drugs: studies on the identification of cytochrome P450 (CYP) isoenzymes involved in formation of their main metabolites and on their capability to inhibit CYP2D6.

artículo científico publicado en 2008

2-methiopropamine, a thiophene analogue of methamphetamine: studies on its metabolism and detectability in the rat and human using GC-MS and LC-(HR)-MS techniques.

artículo científico publicado en 2013

A multi-analyte approach to help in assessing the severity of acute poisonings - Development and validation of a fast LC-MS/MS quantification approach for 45 drugs and their relevant metabolites with one-point calibration

artículo científico publicado en 2017

A qualitative/quantitative approach for the detection of 37 tryptamine-derived designer drugs, 5 β-carbolines, ibogaine, and yohimbine in human urine and plasma using standard urine screening and multi-analyte approaches.

artículo científico publicado en 2013

A simple extraction and LC-MS/MS approach for the screening and identification of over 100 analytes in eight different matrices

artículo científico publicado en 2014

A systematic comparison of four different workup procedures for systematic toxicological analysis of urine samples using gas chromatography-mass spectrometry.

artículo científico publicado en 2008

A validated GC-MS procedure for fast, simple, and cost-effective quantification of glycols and GHB in human plasma and their identification in urine and plasma developed for emergency toxicology

artículo científico publicado en 2011

Absorption, distribution, metabolism and excretion pharmacogenomics of drugs of abuse.

artículo científico publicado en 2011

Advances in analytical toxicology: the current role of liquid chromatography-mass spectrometry in drug quantification in blood and oral fluid

artículo científico publicado en 2004

An automated screening method for drugs and toxic compounds in human serum and urine using liquid chromatography–tandem mass spectrometry ⬇️

artículo científico publicado el 21 de agosto de 2010

An easy and fast adenosine 5'-diphosphate quantification procedure based on hydrophilic interaction liquid chromatography-high resolution tandem mass spectrometry for determination of the in vitro adenosine 5'-triphosphatase activity of the human br

artículo científico publicado en 2017

Analysis of toxic alkaloids in body samples

scientific article published on 14 January 2009

Analytical characterization of N,N-diallyltryptamine (DALT) and 16 ring-substituted derivatives

artículo científico publicado en 2016

Analytical characterization of bioactive N-benzyl-substituted phenethylamines and 5-methoxytryptamines

artículo científico publicado en 2015

Analytical toxicology

artículo científico publicado en 2007

Application of a UHPLC MS/MS-based multianalyte approach for screening and validated quantification of drugs in human blood plasma often requested in the context of brain death diagnosis.

artículo científico publicado en 2014

Automated mass spectral deconvolution and identification system for GC-MS screening for drugs, poisons, and metabolites in urine

artículo científico publicado en 2010

Behavioral and neurochemical characterization of kratom (Mitragyna speciosa) extract

artículo científico publicado en 2013

Benzofuran analogues of amphetamine and methamphetamine: studies on the metabolism and toxicological analysis of 5-APB and 5-MAPB in urine and plasma using GC-MS and LC-(HR)-MS(n) techniques.

artículo científico publicado en 2014

Beta-keto amphetamines: studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography-mass spectrometry

artículo científico publicado en 2010

Biofilm inhibition by an experimental dental resin composite containing octenidine dihydrochloride

artículo científico publicado en 2012

Biotechnological synthesis of drug metabolites using human cytochrome P450 2D6 heterologously expressed in fission yeast exemplified for the designer drug metabolite 4'-hydroxymethyl-alpha-pyrrolidinobutyrophenone

artículo científico publicado en 2007

Biotransformation and detectability of the designer drug 2,5-dimethoxy-4-propylphenethylamine (2C-P) studied in urine by GC-MS, LC-MS(n), and LC-high-resolution-MS(n)

artículo científico publicado en 2014

Biotransformation and detectability of the new psychoactive substances N,N-diallyltryptamine (DALT) derivatives 5-fluoro-DALT, 7-methyl-DALT, and 5,6-methylenedioxy-DALT in urine using GC-MS, LC-MSn, and LC-HR-MS/MS.

artículo científico publicado en 2016

Blood plasma level determination using an automated LC-MSn screening system and electronically stored calibrations exemplified for 22 drugs and two active metabolites often requested in emergency toxicology

scientific article published on 09 August 2018

Blood pressure changes after catheter-based renal denervation are related to reductions in total peripheral resistance.

artículo científico publicado en 2015

Blood pressure reductions following catheter-based renal denervation are not related to improvements in adherence to antihypertensive drugs measured by urine/plasma toxicological analysis

artículo científico publicado en 2015

CYP21-catalyzed production of the long-term urinary metandienone metabolite 17beta-hydroxymethyl-17 alpha-methyl-18-norandrosta-1,4,13-trien-3-one: a contribution to the fight against doping.

artículo científico publicado en 2010

Can JWH-210 and JWH-122 be detected in adipose tissue four weeks after single oral drug administration to rats?

artículo científico publicado en 2014

Case report of accidental poisoning with the tranquilizer xylazine and the anesthetic ketamine confirmed by qualitative and quantitative toxicological analysis using GC-MS and LC-MS(n.).

artículo científico publicado en 2013

Chemistry, Pharmacology, and Metabolism of Emerging Drugs of Abuse ⬇️

artículo científico publicado el 1 de octubre de 2010

Chiral drug analysis using mass spectrometric detection relevant to research and practice in clinical and forensic toxicology

artículo científico publicado en 2012

Coexpression of CPR from various origins enhances biotransformation activity of human CYPs in S. pombe.

artículo científico publicado en 2013

Comparison of urinary on-site immunoassay screening and gas chromatography-mass spectrometry results of 111 patients with suspected poisoning presenting at an emergency department.

artículo científico publicado en 2007

Concentrations and ratios of amphetamine, methamphetamine, MDA, MDMA, and MDEA enantiomers determined in plasma samples from clinical toxicology and driving under the influence of drugs cases by GC-NICI-MS.

artículo científico publicado en 2003

Contribution of human esterases to the metabolism of selected drugs of abuse.

artículo científico publicado en 2014

Convenient gram-scale metabolite synthesis by engineered fission yeast strains expressing functional human P450 systems

artículo científico publicado en 2010

Current applications of high-resolution mass spectrometry in drug metabolism studies.

artículo científico

Current position of high-resolution MS for drug quantification in clinical & forensic toxicology.

artículo científico publicado en 2014

Current status of hyphenated mass spectrometry in studies of the metabolism of drugs of abuse, including doping agents

artículo científico publicado el 25 de agosto de 2011

Cyclic ureas, III: On the metabolism of the enantiomers of cyclic ureas in rats

artículo científico publicado en 1993

Cytochrome P450 dependent metabolism of the new designer drug 1-(3-trifluoromethylphenyl)piperazine (TFMPP). In vivo studies in Wistar and Dark Agouti rats as well as in vitro studies in human liver microsomes.

artículo científico publicado en 2004

Cytochrome P450 inhibition potential of new psychoactive substances of the tryptamine class.

artículo científico publicado en 2015

Cytochrome P450 isoenzymes involved in rat liver microsomal metabolism of californine and protopine.

artículo científico publicado en 2004

Demands on scientific studies in clinical toxicology.

artículo científico publicado en 2006

Designer drug 2,4,5-trimethoxyamphetamine (TMA-2): studies on its metabolism and toxicological detection in rat urine using gas chromatographic/mass spectrometric techniques

artículo científico publicado en 2006

Designer drug 2,5-dimethoxy-4-methyl-amphetamine (DOM, STP): involvement of the cytochrome P450 isoenzymes in formation of its main metabolite and detection of the latter in rat urine as proof of a drug intake using gas chromatography-mass spectrome

artículo científico publicado en 2007

Detection and quantification of benzodiazepines and Z-drugs in human whole blood, plasma, and serum samples as part of a comprehensive multi-analyte LC-MS/MS approach.

artículo científico publicado en 2013

Detection and validated quantification of nine herbal phenalkylamines and methcathinone in human blood plasma by LC-MS/MS with electrospray ionization

artículo científico publicado en 2007

Detection and validated quantification of toxic alkaloids in human blood plasma--comparison of LC-APCI-MS with LC-ESI-MS/MS

artículo científico publicado en 2007

Detection of 4-hydroxycoumarin anticoagulants and their metabolites in urine as part of a systematic toxicological analysis procedure for acidic drugs and poisons by gas chromatography–mass spectrometry after extractive methylation ⬇️

artículo científico publicado el 4 de septiembre de 1998

Determination of 1,4- and 1,5-benzodiazepines in urine using a computerized gas chromatographic—mass spectrometric technique ⬇️

artículo científico publicado el 13 de marzo de 1981

Determination of amphetamine, methamphetamine and amphetamine-derived designer drugs or medicaments in blood and urine ⬇️

artículo científico publicado el 21 de agosto de 1998

Development and validation of LC‐HRMS and GC‐NICI‐MS methods for stereoselective determination of MDMA and its phase I and II metabolites in human urine ⬇️

artículo científico publicado el 1 de julio de 2011

Development and validation of a fast and simple multi-analyte procedure for quantification of 40 drugs relevant to emergency toxicology using GC-MS and one-point calibration

artículo científico publicado en 2013

Development and validation of a liquid-chromatography high-resolution tandem mass spectrometry approach for quantification of nine cytochrome P450 (CYP) model substrate metabolites in an in vitro CYP inhibition cocktail

artículo científico publicado en 2014

Development and validation of a multi-analyte LC-MS/MS approach for quantification of neuroleptics in whole blood, plasma, and serum

artículo científico publicado en 2015

Development of a quantitative approach in blood plasma for low-dosed hallucinogens and opioids using LC-high resolution mass spectrometry

artículo científico publicado en 2017

Development of an in vitro cytochrome P450 cocktail inhibition assay for assessing the inhibition risk of drugs of abuse

artículo científico publicado en 2014

Development of the first metabolite-based LC-MS(n) urine drug screening procedure-exemplified for antidepressants.

artículo científico publicado en 2010

Development, validation, and application of a fast and simple GC-MS method for determination of some therapeutic drugs relevant in emergency toxicology

article by Markus R Meyer et al published 1 October 2011 in Therapeutic Drug Monitoring

Different in vitro and in vivo tools for elucidating the human metabolism of alpha-cathinone-derived drugs of abuse.

artículo científico publicado en 2018

Dimethocaine, a synthetic cocaine analogue: studies on its in-vivo metabolism and its detectability in urine by means of a rat model and liquid chromatography-linear ion-trap (high-resolution) mass spectrometry.

artículo científico publicado en 2014

Dimethocaine, a synthetic cocaine derivative: studies on its in vitro metabolism catalyzed by P450s and NAT2.

artículo científico publicado en 2013

Diphenidine, a new psychoactive substance: metabolic fate elucidated with rat urine and human liver preparations and detectability in urine using GC-MS, LC-MSn , and LC-HR-MSn.

artículo científico publicado en 2016

Direct analysis of the mushroom poisons α- and β-amanitin in human urine using a novel on-line turbulent flow chromatography mode coupled to liquid chromatography-high resolution-mass spectrometry/mass spectrometry

artículo científico publicado en 2013

Distribution of Synthetic Cannabinoids JWH-210, RCS-4 and Δ 9-Tetrahydrocannabinol After Intravenous Administration to Pigs

artículo científico publicado en 2016

Doxepin concentrations in plasma and cerebrospinal fluid.

artículo científico publicado en 2011

Dried urine spots - A novel sampling technique for comprehensive LC-MSn drug screening.

artículo científico publicado en 2017

Drug testing in blood: validated negative-ion chemical ionization gas chromatographic-mass spectrometric assay for enantioselective measurement of the designer drugs MDEA, MDMA, and MDA and its application to samples from a controlled study with MDM

artículo científico publicado en 2005

Drugs of abuse screening in urine as part of a metabolite-based LC-MSn screening concept ⬇️

artículo científico publicado el 1 de mayo de 2011

Elucidation of the metabolites of the novel psychoactive substance 4-methyl-N-ethyl-cathinone (4-MEC) in human urine and pooled liver microsomes by GC-MS and LC-HR-MS/MS techniques and of its detectability by GC-MS or LC-MS(n) standard screening app

artículo científico publicado en 2014

Engineering of human CYP3A enzymes by combination of activating polymorphic variants.

artículo científico publicado en 2012

Fenproporex N-dealkylation to amphetamine--enantioselective in vitro studies in human liver microsomes as well as enantioselective in vivo studies in Wistar and Dark Agouti rats.

artículo científico publicado en 2004

Forensic and clinical toxicology

artículo científico publicado en 2014

Forensic toxicology

artículo científico publicado en 2011

Full validation and application of an ultra high performance liquid chromatographic-tandem mass spectrometric procedure for target screening and quantification of 34 antidepressants in human blood plasma as part of a comprehensive multi-analyte appr

scientific article published on 07 April 2011

Further studies on the role of metabolites in (+/-)-3,4-methylenedioxymethamphetamine-induced serotonergic neurotoxicity.

artículo científico publicado en 2009

GC-MS and LC-(high-resolution)-MS(n) studies on the metabolic fate and detectability of camfetamine in rat urine

artículo científico publicado en 2014

GC-MS, LC-MS(n), LC-high resolution-MS(n), and NMR studies on the metabolism and toxicological detection of mesembrine and mesembrenone, the main alkaloids of the legal high "Kanna" isolated from Sceletium tortuosum

artículo científico publicado en 2014

Gas chromatography-mass spectrometry detection of a norfluoxetine artifact in hydrolyzed urine samples may falsely indicate tranylcypromine ingestion.

artículo científico publicado en 2010

High-resolution mass spectrometry in toxicology: current status and future perspectives.

artículo científico publicado en 2016

Hormonal counterregulation and consecutive glimepiride serum concentrations during severe hypoglycaemia associated with glimepiride therapy.

artículo científico publicado en 2003

Human CYP4Z1 catalyzes the in-chain hydroxylation of lauric acid and myristic acid.

artículo científico publicado en 2009

Human cytochrome P450 kinetic studies on six N-2-methoxybenzyl (NBOMe)-derived new psychoactive substances using the substrate depletion approach

artículo científico publicado en 2017

Hyphenated mass spectrometric techniques-indispensable tools in clinical and forensic toxicology and in doping control

artículo científico publicado en 2006

Identification and differentiation of alkylamine antihistamines and their metabolites in urine by computerized gas chromatography-mass spectrometry

scientific article published on 01 August 1988

Identification of antiarrhythmic drugs and their metabolites in urine

scientific article published on 01 January 1990

Identification of cytochrome P450 enzymes involved in the metabolism of the designer drugs N-(1-phenylcyclohexyl)-3-ethoxypropanamine and N-(1-phenylcyclohexyl)-3-methoxypropanamine.

artículo científico publicado en 2008

Identification of cytochrome p450 enzymes involved in the metabolism of 4'-methyl-alpha-pyrrolidinopropiophenone, a novel scheduled designer drug, in human liver microsomes.

artículo científico publicado en 2003

Identification of human cytochrome P450 2D6 as major enzyme involved in the O-demethylation of the designer drug p-methoxymethamphetamine.

artículo científico publicado en 2004

Identification of monoamine oxidase and cytochrome P450 isoenzymes involved in the deamination of phenethylamine-derived designer drugs (2C-series)

artículo científico publicado en 2006

In situ antibiofilm effect of glass-ionomer cement containing dimethylaminododecyl methacrylate

artículo científico publicado en 2015

In vitro cytochrome P450 inhibition potential of methylenedioxy-derived designer drugs studied with a two-cocktail approach

artículo científico publicado en 2014

In vitro glucuronidation of designer benzodiazepines by human UDP-glucuronyltransferases

scientific article published on 09 August 2018

In vitro monoamine oxidase inhibition potential of alpha-methyltryptamine analog new psychoactive substances for assessing possible toxic risks

artículo científico publicado en 2017

Interactions of phenethylamine-derived psychoactive substances of the 2C-series with human monoamine oxidases

scientific article published on 28 September 2018

Intrahepatic cholestasis following abuse of powdered kratom (Mitragyna speciosa)

artículo científico publicado en 2011

Investigation on the enantioselectivity of the sulfation of the methylenedioxymethamphetamine metabolites 3,4-dihydroxymethamphetamine and 4-hydroxy-3-methoxymethamphetamine using the substrate-depletion approach

artículo científico publicado en 2011

Investigations on the cytochrome P450 (CYP) isoenzymes involved in the metabolism of the designer drugs N-(1-phenyl cyclohexyl)-2-ethoxyethanamine and N-(1-phenylcyclohexyl)-2-methoxyethanamine.

artículo científico publicado en 2008

Investigations on the human hepatic cytochrome P450 isozymes involved in the metabolism of 3,4-methylenedioxy-amphetamine (MDA) and benzodioxolyl-butanamine (BDB) enantiomers.

artículo científico publicado en 2009

Investigations on the stereoselectivity of the phase II metabolism of the 3,4-methylenedioxyethylamphetamine (MDEA) metabolites 3,4-dihydroxyethylamphetamine (DHEA) and 4-hydroxy-3-methoxyethylamphetamine (HMEA)

artículo científico publicado en 2012

Ion suppression and enhancement effects of co-eluting analytes in multi-analyte approaches: systematic investigation using ultra-high-performance liquid chromatography/mass spectrometry with atmospheric-pressure chemical ionization or electrospray i

artículo científico publicado en 2010

Ketamine-derived designer drug methoxetamine: metabolism including isoenzyme kinetics and toxicological detectability using GC-MS and LC-(HR-)MS n ⬇️

artículo científico publicado el 18 de junio de 2013

LC-HR-MS/MS standard urine screening approach: Pros and cons of automated on-line extraction by turbulent flow chromatography versus dilute-and-shoot and comparison with established urine precipitation

artículo científico publicado en 2016

LC-high resolution-MS/MS for identification of 69 metabolites of the new psychoactive substance 1-(4-ethylphenyl-)-N-[(2-methoxyphenyl)methyl] propane-2-amine (4-EA-NBOMe) in rat urine and human liver S9 incubates and comparison of its screening pow

artículo científico publicado en 2017

Lefetamine, a controlled drug and pharmaceutical lead of new designer drugs: synthesis, metabolism, and detectability in urine and human liver preparations using GC-MS, LC-MS(n), and LC-high resolution-MS/MS.

artículo científico publicado en 2015

Liquid chromatographic-electrospray ionization mass spectrometric assay for simultaneous determination of 3,4-methylenedioxymethamphetamine and its metabolites 3,4-methylenedioxyamphetamine, 3,4-dihydroxymethamphetamine, and 4-hydroxy-3-methoxymetha

artículo científico publicado en 2008

Liquid chromatography-high resolution-tandem mass spectrometry using Orbitrap technology for comprehensive screening to detect drugs and their metabolites in blood plasma.

artículo científico publicado en 2017

Liquid chromatography–mass spectrometry in forensic and clinical toxicology ⬇️

artículo científico publicado el 21 de agosto de 1998

Low resolution and high resolution MS for studies on the metabolism and toxicological detection of the new psychoactive substance methoxypiperamide (MeOP).

artículo científico publicado en 2015

Mass spectrometric approaches in impaired driving toxicology.

artículo científico publicado en 2008

Metabolic fate and detectability of the new psychoactive substances 2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25B-NBOMe) and 2-(4-chloro-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25C-NBOMe) in human and

artículo científico publicado en 2016

Metabolic fate of desomorphine elucidated using rat urine, pooled human liver preparations, and human hepatocyte cultures as well as its detectability using standard urine screening approaches

artículo científico publicado en 2016

Metabolic fate of the new synthetic cannabinoid 7'N-5F-ADB in rat, human, and pooled human S9 studied by means of hyphenated high-resolution mass spectrometry

scientific article published on 09 October 2018

Metabolic fate, mass spectral fragmentation, detectability, and differentiation in urine of the benzofuran designer drugs 6-APB and 6-MAPB in comparison to their 5-isomers using GC-MS and LC-(HR)-MS(n) techniques

scientific article published on 25 February 2015

Metabolic patterns of JWH-210, RCS-4, and THC in pig urine elucidated using LC-HR-MS/MS: Do they reflect patterns in humans?

artículo científico publicado en 2016

Metabolism and toxicological detection of the designer drug 4-chloro-2,5-dimethoxyamphetamine in rat urine using gas chromatography-mass spectrometry.

artículo científico publicado en 2008

Metabolism and toxicological detection of the designer drug 4-iodo-2,5-dimethoxy-amphetamine (DOI) in rat urine using gas chromatography-mass spectrometry

scientific article published on 01 July 2007

Metabolism and toxicological detection of the designer drug N-(1-phenylcyclohexyl)-3-methoxypropanamine (PCMPA) in rat urine using gas chromatography-mass spectrometry.

artículo científico publicado en 2008

Metabolism and toxicological detection of the new designer drug 3',4'-methylenedioxy-alpha-pyrrolidinopropiophenone studied in urine using gas chromatography-mass spectrometry.

artículo científico publicado en 2003

Metabolism and toxicological detection of the new designer drug 4'-methoxy-alpha-pyrrolidinopropiophenone studied in rat urine using gas chromatography-mass spectrometry.

artículo científico publicado en 2003

Metabolism of designer drugs of abuse

artículo científico publicado en 2005

Metabolism of designer drugs of abuse: an updated review.

artículo científico publicado en 2010

Metabolism of the new designer drug α-pyrrolidinopropiophenone (PPP) and the toxicological detection of PPP and 4′-methyl-α-pyrrolidinopropiophenone (MPPP) studied in rat urine using gas chromatography-mass spectrometry ⬇️

artículo científico publicado el 5 de noviembre de 2003

Metabolism of the new psychoactive substances N,N-diallyltryptamine (DALT) and 5-methoxy-DALT and their detectability in urine by GC-MS, LC-MSn, and LC-HR-MS-MS.

artículo científico publicado en 2015

Metabolism of the tryptamine-derived new psychoactive substances 5-MeO-2-Me-DALT, 5-MeO-2-Me-ALCHT, and 5-MeO-2-Me-DIPT and their detectability in urine studied by GC-MS, LC-MSn , and LC-HR-MS/MS.

artículo científico publicado en 2017

Metabolism studies of the Kratom alkaloid speciociliatine, a diastereomer of the main alkaloid mitragynine, in rat and human urine using liquid chromatography-linear ion trap mass spectrometry

scientific article published on 20 January 2011

Metabolism studies of the Kratom alkaloids mitraciliatine and isopaynantheine, diastereomers of the main alkaloids mitragynine and paynantheine, in rat and human urine using liquid chromatography-linear ion trap-mass spectrometry

artículo científico publicado en 2011

Methylenedioxy designer drugs: mass spectrometric characterization of their glutathione conjugates by means of liquid chromatography-high-resolution mass spectrometry/mass spectrometry and studies on their glutathionyl transferase inhibition potency

artículo científico publicado en 2014

Michaelis–Menten kinetic analysis of drugs of abuse to estimate their affinity to human P-glycoprotein ⬇️

artículo científico publicado el 27 de diciembre de 2012

Monitoring of kratom or Krypton intake in urine using GC-MS in clinical and forensic toxicology

artículo científico publicado en 2010

Multiple stage MS in analysis of plasma, serum, urine and in vitro samples relevant to clinical and forensic toxicology

artículo científico publicado en 2016

Negative ion chemical ionization gas chromatography-mass spectrometry and atmospheric pressure chemical ionization liquid chromatography-mass spectrometry of low-dosed and/or polar drugs in plasma.

artículo científico publicado en 2002

Negative-Ion Chemical Ionization Gas Chromatography-Mass Spectrometry Assay for Enantioselective Measurement of Amphetamines in Oral Fluid: Application to a Controlled Study with MDMA and Driving Under the Influence Cases

artículo científico publicado en 2007

New Psychoactive Substances 3-Methoxyphencyclidine (3-MeO-PCP) and 3-Methoxyrolicyclidine (3-MeO-PCPy): Metabolic Fate Elucidated with Rat Urine and Human Liver Preparations and their Detectability in Urine by GC-MS, "LC-(High Resolution)-MSn" and "

artículo científico publicado en 2016

New Psychoactive Substances: Chemistry, Pharmacology, Metabolism, and Detectability of Amphetamine Derivatives With Modified Ring Systems

artículo científico

New cathinone‐derived designer drugs 3‐bromomethcathinone and 3‐fluoromethcathinone: studies on their metabolism in rat urine and human liver microsomes using GC–MS and LC–high‐resolution MS and their detectability in urine ⬇️

artículo científico publicado el 1 de febrero de 2012

New designer drug 1-(3,4-methylenedioxybenzyl) piperazine (MDBP): studies on its metabolism and toxicological detection in rat urine using gas chromatography/mass spectrometry.

artículo científico publicado en 2004

New designer drug 1-(3-trifluoromethylphenyl) piperazine (TFMPP): gas chromatography/mass spectrometry and liquid chromatography/mass spectrometry studies on its phase I and II metabolism and on its toxicological detection in rat urine.

artículo científico publicado en 2003

New designer drug 2,5-dimethoxy-4-ethylthio-beta-phenethylamine (2C-T-2): studies on its metabolism and toxicological detection in rat urine using gas chromatography/mass spectrometry.

artículo científico publicado en 2005

New designer drug 4-iodo-2,5-dimethoxy-beta-phenethylamine (2C-I): studies on its metabolism and toxicological detection in rat urine using gas chromatographic/mass spectrometric and capillary electrophoretic/mass spectrometric techniques

artículo científico publicado en 2006

New designer drug 4′-methyl-α-pyrrolidinohexanophenone: studies on its metabolism and toxicological detection in urine using gas chromatography–mass spectrometry ⬇️

artículo científico publicado el 5 de junio de 2003

New designer drug N-(1-phenylcyclohexyl)-3-ethoxypropanamine (PCEPA): studies on its metabolism and toxicological detection in rat urine using gas chromatographic/mass spectrometric techniques

artículo científico publicado en 2006

New designer drug p-methoxymethamphetamine: studies on its metabolism and toxicological detection in urine using gas chromatography-mass spectrometry.

artículo científico publicado en 2003

New designer drug, 2,5-dimethoxy-4-propylthio-beta-phenethylamine (2C-T-7): studies on its metabolism and toxicological detection in rat urine using gas chromatography/mass spectrometry.

artículo científico publicado en 2005

New designer drugs N-(1-phenylcyclohexyl)-2-ethoxyethanamine (PCEEA) and N-(1-phenylcyclohexyl)-2-methoxyethanamine (PCMEA): Studies on their metabolism and toxicological detection in rat urine using gas chromatographic/mass spectrometric techniques

artículo científico publicado en 2008

New psychoactive substances: Studies on the metabolism of XLR-11, AB-PINACA, FUB-PB-22, 4-methoxy-α-PVP, 25-I-NBOMe, and meclonazepam using human liver preparations in comparison to primary human hepatocytes, and human urine

artículo científico

Nonlinear pharmacokinetics of (+/-)3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") and its major metabolites in squirrel monkeys at plasma concentrations of MDMA that develop after typical psychoactive doses.

artículo científico publicado en 2008

Objective assessment of nonadherence and unknown co-medication in hospitalized patients

artículo científico publicado en 2012

On the metabolism and the toxicological analysis of methylenedioxyphenylalkylamine designer drugs by gas chromatography-mass spectrometry

artículo científico publicado en 1996

Orbitrap technology for comprehensive metabolite-based liquid chromatographic-high resolution-tandem mass spectrometric urine drug screening - exemplified for cardiovascular drugs

artículo científico publicado en 2015

P-glycoprotein interactions of novel psychoactive substances - stimulation of ATP consumption and transport across Caco-2 monolayers.

artículo científico publicado en 2015

Paper Spray Ionization Coupled to High Resolution Tandem Mass Spectrometry for Comprehensive Urine Drug Testing in Comparison to Liquid Chromatography-Coupled Techniques after Urine Precipitation or Dried Urine Spot Workup

artículo científico publicado en 2017

Perspectives of liquid chromatography coupled to low- and high-resolution mass spectrometry for screening, identification, and quantification of drugs in clinical and forensic toxicology.

artículo científico publicado en 2010

Pharmacokinetics of (synthetic) cannabinoids in pigs and their relevance for clinical and forensic toxicology.

artículo científico publicado en 2016

Phase I and II metabolites of speciogynine, a diastereomer of the main Kratom alkaloid mitragynine, identified in rat and human urine by liquid chromatography coupled to low‐ and high‐resolution linear ion trap mass spectrometry ⬇️

artículo científico publicado el 21 de octubre de 2010

Pitfalls in drug testing by hyphenated low- and high-resolution mass spectrometry

artículo científico publicado en 2020

Pooled human liver preparations, HepaRG, or HepG2 cell lines for metabolism studies of new psychoactive substances? A study using MDMA, MDBD, butylone, MDPPP, MDPV, MDPB, 5-MAPB, and 5-API as examples

artículo científico publicado en 2017

Position of chromatographic techniques in screening for detection of drugs or poisons in clinical and forensic toxicology and/or doping control.

artículo científico publicado en 2004

Power of Orbitrap-based LC-high resolution-MS/MS for comprehensive drug testing in urine with or without conjugate cleavage or using dried urine spots after on-spot cleavage in comparison to established LC-MSn or GC-MS procedures.

artículo científico publicado en 2017

Prevalence of illicit drug use in plasmapheresis donors.

artículo científico publicado en 2003

Production and NMR analysis of the human ibuprofen metabolite 3-hydroxyibuprofen

artículo científico publicado en 2011

Production of human phase 1 and 2 metabolites by whole-cell biotransformation with recombinant microbes.

artículo científico publicado en 2010

Qualitative metabolism assessment and toxicological detection of xylazine, a veterinary tranquilizer and drug of abuse, in rat and human urine using GC-MS, LC-MSn, and LC-HR-MSn.

artículo científico publicado en 2013

Qualitative studies on the metabolism and the toxicological detection of the fentanyl-derived designer drugs 3-methylfentanyl and isofentanyl in rats using liquid chromatography-linear ion trap-mass spectrometry (LC-MS(n)).

artículo científico publicado en 2011

Quantification of 33 antidepressants by LC-MS/MS--comparative validation in whole blood, plasma, and serum

Review: LC coupled to low- and high-resolution mass spectrometry for new psychoactive substance screening in biological matrices - Where do we stand today?

artículo científico publicado en 2016

Role of gas chromatography-mass spectrometry with negative ion chemical ionization in clinical and forensic toxicology, doping control, and biomonitoring

artículo científico publicado en 2002

Screening for the detection of angiotensin-converting enzyme inhibitors, their metabolites, and AT II receptor antagonists

scientific article published on 01 December 1998

Screening procedure for detecting butyrophenone and bisfluorophenyl neuroleptics in urine using a computerized gas chromatographic—mass spectrometric technique ⬇️

artículo científico publicado el 14 de enero de 1983

Screening procedure for detection of antidepressants of the selective serotonin reuptake inhibitor type and their metabolites in urine as part of a modified systematic toxicological analysis procedure using gas chromatography-mass spectrometry

artículo científico publicado en 2000

Screening procedure for detection of dihydropyridine calcium channel blocker metabolites in urine as part of a systematic toxicological analysis procedure for acidic compounds by gas chromatography-mass spectrometry after extractive methylation

scientific article published on 01 March 1999

Screening procedures for simultaneous detection of several drug classes used for high throughput toxicological analyses and doping control. A review.

artículo científico publicado en 2000

Screening, library-assisted identification and validated quantification of fifteen neuroleptics and three of their metabolites in plasma by liquid chromatography/mass spectrometry with atmospheric pressure chemical ionization.

artículo científico publicado en 2003

Simultaneous LC-MS/MS determination of JWH-210, RCS-4, ∆(9)-tetrahydrocannabinol, and their main metabolites in pig and human serum, whole blood, and urine for comparing pharmacokinetic data

artículo científico publicado en 2015

Studies on the human metabolism and the toxicologic detection of the cough suppressant dropropizine in urine using gas chromatography-mass spectrometry.

artículo científico publicado en 2004

Studies on the metabolism and detectability of the designer drug β-naphyrone in rat urine using GC-MS and LC-HR-MS/MS

scientific article published on 10 January 2013

Studies on the metabolism and the detectability of 4-methyl-amphetamine and its isomers 2-methyl-amphetamine and 3-methyl-amphetamine in rat urine using GC-MS and LC-(high-resolution)-MSn.

artículo científico publicado en 2014

Studies on the metabolism and toxicological detection of glaucine, an isoquinoline alkaloid fromGlaucium flavum(Papaveraceae), in rat urine using GC-MS, LC-MSnand LC-high-resolution MSn

artículo científico publicado en 2013

Studies on the metabolism and toxicological detection of the Eschscholtzia californica alkaloids californine and protopine in urine using gas chromatography-mass spectrometry.

artículo científico publicado en 2003

Studies on the metabolism and toxicological detection of the designer drug 2,5-dimethoxy-4-methyl-beta- phenethylamine (2C-D) in rat urine using gas chromatographic/mass spectrometric techniques

artículo científico publicado en 2006

Studies on the metabolism and toxicological detection of the designer drug 4-ethyl-2,5-dimethoxy-β-phenethylamine (2C-E) in rat urine using gas chromatographic–mass spectrometric techniques☆

artículo científico publicado en 2006

Studies on the metabolism and toxicological detection of the designer drug 4-methylthioamphetamine (4-MTA) in human urine using gas chromatography-mass spectrometry.

artículo científico publicado en 2005

Studies on the metabolism and toxicological detection of the new designer drug 4'-methyl-alpha-pyrrolidinobutyrophenone (MPBP) in rat urine using gas chromatography-mass spectrometry.

artículo científico publicado en 2005

Studies on the metabolism and toxicological detection of the new designer drug N-benzylpiperazine in urine using gas chromatography-mass spectrometry.

artículo científico publicado en 2002

Studies on the metabolism and toxicological detection of the new psychoactive designer drug 2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25I-NBOMe) in human and rat urine using GC-MS, LC-MS(n), and LC-HR-MS/MS

artículo científico publicado en 2015

Studies on the metabolism of the Delta9-tetrahydrocannabinol precursor Delta9-tetrahydrocannabinolic acid A (Delta9-THCA-A) in rat using LC-MS/MS, LC-QTOF MS and GC-MS techniques

artículo científico publicado en 2009

Studies on the metabolism of the α-pyrrolidinophenone designer drug methylenedioxy-pyrovalerone (MDPV) in rat and human urine and human liver microsomes using GC-MS and LC-high-resolution MS and its detectability in urine by GC-MS

artículo científico publicado en 2010

Studies on the toxicological detection of the designer drug 4-bromo-2,5-dimethoxy-beta-phenethylamine (2C-B) in rat urine using gas chromatography-mass spectrometry

scientific article published on 15 September 2006

Sulfation of the 3,4-methylenedioxymethamphetamine (MDMA) metabolites 3,4-dihydroxymethamphetamine (DHMA) and 4-hydroxy-3-methoxymethamphetamine (HMMA) and their capability to inhibit human sulfotransferases ⬇️

artículo científico publicado el 2 de febrero de 2011

Sympathomimetic toxicity in a case of analytically confirmed recreational use of naphyrone (naphthylpyrovalerone) ⬇️

artículo científico publicado el 8 de julio de 2011

Systematic comparison of bias and precision data obtained with multiple-point and one-point calibration in six validated multianalyte assays for quantification of drugs in human plasma

artículo científico publicado en 2007

Systematic forensic toxicological analysis by GC-MS in serum using automated mass spectral deconvolution and identification system

artículo científico publicado en 2015

Systematic investigation of ion suppression and enhancement effects of fourteen stable-isotope-labeled internal standards by their native analogues using atmospheric-pressure chemical ionization and electrospray ionization and the relevance for mult

artículo científico publicado en 2010

The NTCP-inhibitor Myrcludex B: Effects on Bile Acid Disposition and Tenofovir Pharmacokinetics.

artículo científico publicado en 2017

The antispasmodic drug mebeverine leads to positive amphetamine results by fluorescence polarization immunoassay (FPIA)--studies on the toxicological analysis of urine by FPIA and GC-MS.

artículo científico publicado en 2001

The breast feeding mother and xenon anaesthesia: four case reports. Breast feeding and xenon anaesthesia

artículo científico publicado en 2010

The diagnostic value of determining the hydroxy metabolite of glimepiride (M1) in blood serum in cases of severe hypoglycaemia associated with glimepiride therapy.

artículo científico publicado en 2004

The in vivo TRPV6 protein starts at a non-AUG triplet, decoded as methionine, upstream of canonical initiation at AUG

artículo científico publicado en 2013

The in vivo and in vitro metabolism and the detectability in urine of 3',4'-methylenedioxy-alpha-pyrrolidinobutyrophenone (MDPBP), a new pyrrolidinophenone-type designer drug, studied by GC-MS and LC-MS(n.).

artículo científico publicado en 2013

The role of human UDP-glucuronyltransferases on the formation of the methylenedioxymethamphetamine (ecstasy) phase II metabolites R- and S-3-methoxymethamphetamine 4-O-glucuronides.

artículo científico publicado en 2009

The role of human hepatic cytochrome P450 isozymes in the metabolism of racemic 3,4-methylenedioxyethylamphetamine and its single enantiomers.

artículo científico publicado en 2009

Toward high-throughput drug screening using mass spectrometry

artículo científico publicado en 2005

Towards a universal LC-MS screening procedure - can an LIT LC-MS(n) screening approach and reference library be used on a quadrupole-LIT hybrid instrument?

artículo científico publicado en 2012

Toxicokinetics and analytical toxicology of amphetamine-derived designer drugs ('Ecstasy')

artículo científico publicado en 2000

Toxicokinetics of amphetamines: metabolism and toxicokinetic data of designer drugs, amphetamine, methamphetamine, and their N-alkyl derivatives

artículo científico publicado en 2002

Toxicokinetics of drugs of abuse: current knowledge of the isoenzymes involved in the human metabolism of tetrahydrocannabinol, cocaine, heroin, morphine, and codeine

artículo científico publicado en 2006

Toxicokinetics of lefetamine and derived diphenylethylamine designer drugs-Contribution of human cytochrome P450 isozymes to their main phase I metabolic steps

artículo científico publicado en 2015

Toxicokinetics of novel psychoactive substances: characterization of N-acetyltransferase (NAT) isoenzymes involved in the phase II metabolism of 2C designer drugs

artículo científico publicado en 2014

Toxicological detection of pholcodine and its metabolites in urine and hair using radio immunoassay, fluorescence polarisation immunoassay, enzyme immunoassay, and gas chromatography-mass spectrometry

artículo científico publicado en 1990

Toxicological detection of selegiline and its metabolites in urine using fluorescence polarization immunoassay (FPIA) and gas chromatography-mass spectrometry (GC-MS) and differentiation by enantioselective GC-MS of the intake of selegiline from abu

artículo científico publicado el 1 de enero de 1992

Toxicological detection of the designer drug 3,4-methylenedioxyethylamphetamine (MDE, "Eve") and its metabolites in urine by gas chromatography-mass spectrometry and fluorescence polarization immunoassay.

artículo científico publicado en 1996

Toxicological detection of the new designer drug 1-(4-methoxyphenyl)piperazine and its metabolites in urine and differentiation from an intake of structurally related medicaments using gas chromatography-mass spectrometry.

artículo científico publicado en 2003

Ultra high performance liquid chromatographic-tandem mass spectrometric multi-analyte procedure for target screening and quantification in human blood plasma: validation and application for 31 neuroleptics, 28 benzodiazepines, and Z-drugs

artículo científico publicado en 2011

Urinary excretion kinetics of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) and its phase I and phase II metabolites in humans following controlled MDMA administration

artículo científico publicado en 2011

Use of fission yeast heterologously expressing human cytochrome P450 2B6 in biotechnological synthesis of the designer drug metabolite N-(1-phenylcyclohexyl)-2-hydroxyethanamine.

artículo científico publicado en 2009

Use of liquid chromatography coupled to low- and high-resolution linear ion trap mass spectrometry for studying the metabolism of paynantheine, an alkaloid of the herbal drug Kratom in rat and human urine.

artículo científico publicado en 2009

Validated assay for quantification of oxcarbazepine and its active dihydro metabolite 10-hydroxycarbazepine in plasma by atmospheric pressure chemical ionization liquid chromatography/mass spectrometry

artículo científico publicado en 2002

What is the contribution of human FMO3 in the N-oxygenation of selected therapeutic drugs and drugs of abuse?

artículo científico publicado en 2016

What is the future of (ultra) high performance liquid chromatography coupled to low and high resolution mass spectrometry for toxicological drug screening? ⬇️

artículo científico publicado el 27 de agosto de 2012

Whole-cell biotransformation assay for investigation of the human drug metabolizing enzyme CYP3A7

artículo científico publicado en 2010

Witnessed drug intake before planned denervation--always harmless?

scientific article published on 28 October 2014

[Acylanilides. 3. Methemoglobin formation and metabolism in the rat]

artículo científico publicado en 1988

[Pharmacy at the University of the Saarlands]

artículo científico publicado en 1997

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