Lista de obras - Jian Zhao - Dominio Público Uruguay

A GPCR/secretase complex regulates beta- and gamma-secretase specificity for Abeta production and contributes to AD pathogenesis.

artículo científico publicado en 2010

A herbal medicine for Alzheimer's disease and its active constituents promote neural progenitor proliferation.

artículo científico publicado en 2015

A tricyclic antidepressant, amoxapine, reduces amyloid-β generation through multiple serotonin receptor 6-mediated targets.

artículo científico publicado en 2017

Activation of aryl hydrocarbon receptor (ahr) by tranilast, an anti-allergy drug, promotes miR-302 expression and cell reprogramming.

artículo científico publicado en 2013

An Anti-Parkinson's Disease Drug via Targeting Adenosine A2A Receptor Enhances Amyloid-β Generation and γ-Secretase Activity

artículo científico publicado en 2016

Anti-HIV agent trichosanthin enhances the capabilities of chemokines to stimulate chemotaxis and G protein activation, and this is mediated through interaction of trichosanthin and chemokine receptors

artículo científico publicado en 1999

Arrestins in Metabolic Regulation

artículo científico publicado el 1 de enero de 2013

Attenuation of delta opioid receptor-mediated signaling by kainic acid in neural cells: involvement of protein kinase C and intracellular Ca2+.

artículo científico publicado en 1999

Attenuation of nociceptin/orphanin FQ-induced signaling by N-methyl-D-aspartate in neuronal cells

artículo científico publicado en 1998

Axoneme polyglutamylation regulated by Joubert syndrome protein ARL13B controls ciliary targeting of signaling molecules ⬇️

artículo científico publicado en 2018

Beta-arrestin-1 protein represses adipogenesis and inflammatory responses through its interaction with peroxisome proliferator-activated receptor-gamma (PPARgamma)

artículo científico publicado en 2011

Beta-arrestin-1 protein represses diet-induced obesity

artículo científico publicado en 2011

Carboxyl Terminus of Delta Opioid Receptor Is Required for Agonist-Dependent Receptor Phosphorylation ⬇️

artículo científico publicado el 8 de septiembre de 1997

Carboxyl terminal of rhodopsin kinase is required for the phosphorylation of photo-activated rhodopsin.

artículo científico publicado en 1998

Chemokine receptor CCR5 functionally couples to inhibitory G proteins and undergoes desensitization ⬇️

artículo científico publicado el 1 de octubre de 1998

Deficiency of a beta-arrestin-2 signal complex contributes to insulin resistance.

artículo científico publicado en 2009

Derivation of induced pluripotent stem cells TUSMi006 from an 87-year old Chinese Han Alzheimer's disease patient carrying GRINB and SORL1 mutations

scientific article published on 25 July 2018

Differential neurotoxicity of etorphine-like opiates: lack of correlation with their ability to activate opiate receptors.

artículo científico publicado en 1998

Direct conversion of astrocytes into neuronal cells by drug cocktail

artículo científico publicado en 2015

ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth.

artículo científico publicado en 2003

Endogenous opioid receptor-like receptor in human neuroblastoma SK-N-SH cells: activation of inhibitory G protein and homologous desensitization

artículo científico publicado en 1997

Establishment of TUSMi003-A, an induced pluripotent stem cell (iPSC) line from a 62-year old Chinese Han patient with Alzheimer's disease with ApoE3/4 genetic background

artículo científico publicado en 2018

Establishment of TUSMi004-A, an induced pluripotent stem cell (iPSC) line from a 32-year old Chinese Han patient with Obsessive-Compulsive Disorder (OCD)

scientific article published on 24 August 2018

Establishment of TUSMi005-A, an induced pluripotent stem cell (iPSC) line from a 32-year old Chinese Han patient with Bipolar Disorder (BD)

article

Establishment of TUSMi007-A, an induced pluripotent stem cell (iPSC) line from an 83-year old Chinese Han patient with Alzheimer's disease (AD)

scientific article published on 28 November 2018

Evoking plasmin for beta-amyloid clearance.

artículo científico publicado en 2008

Expression, Purification and Characterization of Regulatory Subunit of Type I cAMP-dependent Protein Kinase in E.coli

artículo científico publicado en 1999

Five-transmembrane domains appear sufficient for a G protein-coupled receptor: functional five-transmembrane domain chemokine receptors

artículo científico publicado en 1999

Functional expression of opioid receptor-like receptor and its endogenous specific agonist nociceptin/orphanin FQ during mouse embryogenesis.

artículo científico publicado en 1997

Generation of a human control PBMC derived iPS cell line TUSMi001-A from a healthy male donor of Han Chinese genetic background

artículo científico publicado en 2017

Generation of a human induced pluripotent stem cell line from a 65-year old healthy female donor with Chinese Han genetic background.

artículo científico publicado en 2017

Generation of neural progenitor cells by chemical cocktails and hypoxia

artículo científico publicado en 2014

Generation of neural progenitor cells by chemical cocktails and hypoxia

artículo científico publicado en 2015

Loss of betaarrestin1 and betaarrestin2 contributes to pulmonary hypoplasia and neonatal lethality in mice.

artículo científico publicado en 2010

Loss of β-arrestin2 mediates pancreatic-islet dysfunction in mice.

artículo científico publicado en 2013

Molecular characterization and functional expression of opioid receptor-like1 receptor.

artículo científico publicado en 1997

Multiple interactions between RNA polymerase I, TIF-IA and TAF(I) subunits regulate preinitiation complex assembly at the ribosomal gene promoter

artículo científico publicado en 2002

N-Methyl-D-aspartate attenuates opioid receptor-mediated G protein activation and this process involves protein kinase C.

artículo científico publicado en 1998

NF-κB directly regulates β-arrestin-1 expression and forms a negative feedback circuit in TNF-α-induced cell death

artículo científico publicado en 2018

Nmnat2 delays axon degeneration in superior cervical ganglia dependent on its NAD synthesis activity.

artículo científico publicado en 2009

Nuclear actin and myosin I are required for RNA polymerase I transcription.

artículo científico publicado en 2004

Promotion of regulatory T cell induction by immunomodulatory herbal medicine licorice and its two constituents.

artículo científico publicado en 2015

Rapamycin and other longevity-promoting compounds enhance the generation of mouse induced pluripotent stem cells.

artículo científico publicado en 2011

Smart Soup, a traditional Chinese medicine formula, ameliorates amyloid pathology and related cognitive deficits

artículo científico publicado en 2014

Stabilization of mouse haploid embryonic stem cells with combined kinase and signal modulation

artículo científico publicado en 2017

Targeting the γ-/β-secretase interaction reduces β-amyloid generation and ameliorates Alzheimer's disease-related pathogenesis

artículo científico publicado en 2015

The combination of aricept with a traditional Chinese medicine formula, smart soup, may be a novel way to treat Alzheimer's disease.

artículo científico publicado en 2015

Traditional Chinese Nootropic Medicine Radix Polygalae and Its Active Constituent Onjisaponin B Reduce β-Amyloid Production and Improve Cognitive Impairments

artículo científico publicado en 2016

Transdifferentiation: a new promise for neurodegenerative diseases

scientific article published on 06 August 2018

Why cell reprogramming is functionally linked to aging?

artículo científico

beta-arrestin differentially regulates the chemokine receptor CXCR4-mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4

artículo científico publicado en 2000

mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability

artículo científico publicado en 2004

β-Arrestin-1 directly interacts with Gαs and regulates its function

artículo científico publicado en 2013

β-Arrestin1 regulates the morphology and dynamics of microglia in zebrafish in vivo.

artículo científico publicado en 2015

β-arrestin-1 contributes to brown fat function and directly interacts with PPARα and PPARγ.

artículo científico publicado en 2016

β-arrestin1 regulates γ-secretase complex assembly and modulates amyloid-β pathology

artículo científico publicado en 2012

γ-Secretase Modulators and Inhibitors Induce Different Conformational Changes of Presenilin 1 Revealed by FLIM and FRET.

artículo científico publicado en 2015

Lista de obras de Jian Zhao

A GPCR/secretase complex regulates beta- and gamma-secretase specificity for Abeta production and contributes to AD pathogenesis.

A herbal medicine for Alzheimer's disease and its active constituents promote neural progenitor proliferation.

A tricyclic antidepressant, amoxapine, reduces amyloid-β generation through multiple serotonin receptor 6-mediated targets.

Activation of aryl hydrocarbon receptor (ahr) by tranilast, an anti-allergy drug, promotes miR-302 expression and cell reprogramming.

An Anti-Parkinson's Disease Drug via Targeting Adenosine A2A Receptor Enhances Amyloid-β Generation and γ-Secretase Activity

Anti-HIV agent trichosanthin enhances the capabilities of chemokines to stimulate chemotaxis and G protein activation, and this is mediated through interaction of trichosanthin and chemokine receptors

Arrestins in Metabolic Regulation

Attenuation of delta opioid receptor-mediated signaling by kainic acid in neural cells: involvement of protein kinase C and intracellular Ca2+.

Attenuation of nociceptin/orphanin FQ-induced signaling by N-methyl-D-aspartate in neuronal cells

Axoneme polyglutamylation regulated by Joubert syndrome protein ARL13B controls ciliary targeting of signaling molecules ⬇️

Beta-arrestin-1 protein represses adipogenesis and inflammatory responses through its interaction with peroxisome proliferator-activated receptor-gamma (PPARgamma)

Beta-arrestin-1 protein represses diet-induced obesity

Carboxyl Terminus of Delta Opioid Receptor Is Required for Agonist-Dependent Receptor Phosphorylation ⬇️

Carboxyl terminal of rhodopsin kinase is required for the phosphorylation of photo-activated rhodopsin.

Chemokine receptor CCR5 functionally couples to inhibitory G proteins and undergoes desensitization ⬇️

Deficiency of a beta-arrestin-2 signal complex contributes to insulin resistance.

Derivation of induced pluripotent stem cells TUSMi006 from an 87-year old Chinese Han Alzheimer's disease patient carrying GRINB and SORL1 mutations

Differential neurotoxicity of etorphine-like opiates: lack of correlation with their ability to activate opiate receptors.

Direct conversion of astrocytes into neuronal cells by drug cocktail

ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth.

Endogenous opioid receptor-like receptor in human neuroblastoma SK-N-SH cells: activation of inhibitory G protein and homologous desensitization

Establishment of TUSMi003-A, an induced pluripotent stem cell (iPSC) line from a 62-year old Chinese Han patient with Alzheimer's disease with ApoE3/4 genetic background

Establishment of TUSMi004-A, an induced pluripotent stem cell (iPSC) line from a 32-year old Chinese Han patient with Obsessive-Compulsive Disorder (OCD)

Establishment of TUSMi005-A, an induced pluripotent stem cell (iPSC) line from a 32-year old Chinese Han patient with Bipolar Disorder (BD)

Establishment of TUSMi007-A, an induced pluripotent stem cell (iPSC) line from an 83-year old Chinese Han patient with Alzheimer's disease (AD)

Evoking plasmin for beta-amyloid clearance.

Expression, Purification and Characterization of Regulatory Subunit of Type I cAMP-dependent Protein Kinase in E.coli

Five-transmembrane domains appear sufficient for a G protein-coupled receptor: functional five-transmembrane domain chemokine receptors

Functional expression of opioid receptor-like receptor and its endogenous specific agonist nociceptin/orphanin FQ during mouse embryogenesis.

Generation of a human control PBMC derived iPS cell line TUSMi001-A from a healthy male donor of Han Chinese genetic background

Generation of a human induced pluripotent stem cell line from a 65-year old healthy female donor with Chinese Han genetic background.

Generation of neural progenitor cells by chemical cocktails and hypoxia

Generation of neural progenitor cells by chemical cocktails and hypoxia

Loss of betaarrestin1 and betaarrestin2 contributes to pulmonary hypoplasia and neonatal lethality in mice.

Loss of β-arrestin2 mediates pancreatic-islet dysfunction in mice.

Molecular characterization and functional expression of opioid receptor-like1 receptor.

Multiple interactions between RNA polymerase I, TIF-IA and TAF(I) subunits regulate preinitiation complex assembly at the ribosomal gene promoter

N-Methyl-D-aspartate attenuates opioid receptor-mediated G protein activation and this process involves protein kinase C.

NF-κB directly regulates β-arrestin-1 expression and forms a negative feedback circuit in TNF-α-induced cell death

Nmnat2 delays axon degeneration in superior cervical ganglia dependent on its NAD synthesis activity.

Nuclear actin and myosin I are required for RNA polymerase I transcription.

Promotion of regulatory T cell induction by immunomodulatory herbal medicine licorice and its two constituents.

Rapamycin and other longevity-promoting compounds enhance the generation of mouse induced pluripotent stem cells.

Smart Soup, a traditional Chinese medicine formula, ameliorates amyloid pathology and related cognitive deficits

Stabilization of mouse haploid embryonic stem cells with combined kinase and signal modulation

Targeting the γ-/β-secretase interaction reduces β-amyloid generation and ameliorates Alzheimer's disease-related pathogenesis

The combination of aricept with a traditional Chinese medicine formula, smart soup, may be a novel way to treat Alzheimer's disease.

Traditional Chinese Nootropic Medicine Radix Polygalae and Its Active Constituent Onjisaponin B Reduce β-Amyloid Production and Improve Cognitive Impairments

Transdifferentiation: a new promise for neurodegenerative diseases

Why cell reprogramming is functionally linked to aging?

beta-arrestin differentially regulates the chemokine receptor CXCR4-mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4

mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability

β-Arrestin-1 directly interacts with Gαs and regulates its function

β-Arrestin1 regulates the morphology and dynamics of microglia in zebrafish in vivo.

β-arrestin-1 contributes to brown fat function and directly interacts with PPARα and PPARγ.

β-arrestin1 regulates γ-secretase complex assembly and modulates amyloid-β pathology

γ-Secretase Modulators and Inhibitors Induce Different Conformational Changes of Presenilin 1 Revealed by FLIM and FRET.