Lista de obras - Mikael Akke - Dominio Público Uruguay

15N NMR assignments and chemical shift analysis of uniformly labeled15N calbindin D9kin the apo, (Cd2+)1and (Ca2+)2states ⬇️

artículo científico publicado el 1 de junio de 1992

A De Novo Designed Coiled-Coil Peptide with a Reversible pH-Induced Oligomerization Switch

artículo científico publicado en 2016

Adsorption of unfolded Cu/Zn superoxide dismutase onto hydrophobic surfaces catalyzes its formation of amyloid fibrils

scientific article published on 01 December 2019

Backbone H, C, and N resonance assignments of BoMan26A, a β-mannanase of the glycoside hydrolase family 26 from the human gut bacterium Bacteroides ovatus

Backbone H, C, and N resonance assignments of the ligand binding domain of the human wildtype glucocorticoid receptor and the F602S mutant variant

artículo científico publicado en 2018

Backbone dynamics of calcium-loaded calbindin D9k studied by two-dimensional proton-detected 15N NMR spectroscopy

artículo científico publicado el 26 de mayo de 1992

Chemical Shifts of the Carbohydrate Binding Domain of Galectin-3 from Magic Angle Spinning NMR and Hybrid Quantum Mechanics/Molecular Mechanics Calculations.

artículo científico publicado en 2018

Computational design of a leucine-rich repeat protein with a predefined geometry

artículo científico publicado en 2014

Conformational Entropies and Order Parameters: Convergence, Reproducibility, and Transferability

scientific article published on 01 January 2014

Conformational Entropy of FK506 Binding to FKBP12 Determined by Nuclear Magnetic Resonance Relaxation and Molecular Dynamics Simulations

artículo científico publicado en 2018

Conformational dynamics and thermodynamics of protein–ligand binding studied by NMR relaxation ⬇️

artículo científico publicado el 1 de abril de 2012

Conserved S/T Residues of the Human Chaperone DNAJB6 Are Required for Effective Inhibition of Aβ42 Amyloid Fibril Formation

scientific article published on 30 July 2018

Cu/Zn Superoxide Dismutase Forms Amyloid Fibrils under Near-Physiological Quiescent Conditions: The Roles of Disulfide Bonds and Effects of Denaturant

artículo científico publicado en 2017

Designing interactions by control of protein-ligand complex conformation: tuning arginine-arene interaction geometry for enhanced electrostatic protein-ligand interactions.

artículo científico publicado en 2017

Dynamic allosteric communication pathway directing differential activation of the glucocorticoid receptor

scientific article published on 17 July 2020

Dynamics of Aromatic Side Chains in the Active Site of FKBP12.

artículo científico publicado en 2016

Elucidation of hydrogen bonding patterns in ligand-free, lactose- and glycerol-bound galectin-3C by neutron crystallography to guide drug design.

artículo científico publicado en 2018

From snapshot to movie: phi analysis of protein folding transition states taken one step further

artículo científico publicado en 1999

Interplay between Conformational Entropy and Solvation Entropy in Protein-Ligand Binding

scientific article published on 23 January 2019

Local unfolding and aggregation mechanisms of SOD1: a Monte Carlo exploration.

artículo científico publicado en 2013

Minute Additions of DMSO Affect Protein Dynamics Measurements by NMR Relaxation Experiments through Significant Changes in Solvent Viscosity

artículo científico publicado en 2018

Molecular insights into substrate recognition and catalytic mechanism of the chaperone and FKBP peptidyl-prolyl isomerase SlyD

artículo científico publicado en 2016

Nuclear magnetic resonance studies of the internal dynamics in Apo, (Cd2+)1 and (Ca2+)2 calbindin D9k. The rates of amide proton exchange with solvent

artículo científico publicado el 20 de octubre de 1992

Off-resonance rotating-frame relaxation dispersion experiment for 13C in aromatic side chains using L-optimized TROSY-selection

artículo científico publicado en 2014

Pervasive conformational fluctuations on microsecond time scales in a fibronectin type III domain

artículo científico publicado el 1 de enero de 1998

Protein conformational exchange measured by 1H R1ρ relaxation dispersion of methyl groups.

artículo científico publicado en 2013

Rapid NMR Relaxation Measurements Using Optimal Nonuniform Sampling of Multidimensional Accordion Data Analyzed by a Sparse Reconstruction Method

scientific article published on 26 June 2019

Revealing Well-Defined Soluble States during Amyloid Fibril Formation by Multilinear Analysis of NMR Diffusion Data

scientific article published on 12 November 2019

Ring flips revisited: (13)C relaxation dispersion measurements of aromatic side chain dynamics and activation barriers in basic pancreatic trypsin inhibitor.

artículo científico publicado en 2014

Rotamer Jumps, Proton Exchange, and Amine Inversion Dynamics of Dimethylated Lysine Residues in Proteins Resolved by pH-Dependent 1H and 13C NMR Relaxation Dispersion

artículo científico publicado en 2019

Signal transduction versus buffering activity in Ca2+–binding proteins ⬇️

artículo científico publicado el 1 de abril de 1994

Slow aromatic ring flips detected despite near-degenerate NMR frequencies of the exchanging nuclei.

artículo científico publicado en 2013

Solution Structure of (Cd2+)1-calbindin D9kReveals Details of the Stepwise Structural Changes along the Aporarr;(Ca2+)rarr;(Ca)Binding Pathway ⬇️

artículo científico publicado el 8 de septiembre de 1995

Stability and Local Unfolding of SOD1 in the Presence of Protein Crowders

scientific article published on 26 February 2019

Starting-Condition Dependence of Order Parameters Derived from Molecular Dynamics Simulations.

artículo científico publicado en 2010

Structural Analysis of a Complex between Small Ubiquitin-like Modifier 1 (SUMO1) and the ZZ Domain of CREB-binding Protein (CBP/p300) Reveals a New Interaction Surface on SUMO

artículo científico publicado en 2016

Structural Insights into the Calcium-Mediated Allosteric Transition in the C-Terminal Domain of Calmodulin from Nuclear Magnetic Resonance Measurements.

artículo científico publicado en 2015

Structural characterization of the microbial enzyme urocanate reductase mediating imidazole propionate production

artículo científico publicado en 2021

Structural model of dodecameric heat-shock protein Hsp21: Flexible N-terminal arms interact with client proteins while C-terminal tails maintain the dodecamer and chaperone activity.

artículo científico publicado en 2017

Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity

artículo científico publicado en 2017

The Dynameomics Entropy Dictionary: A Large-Scale Assessment of Conformational Entropy across Protein Fold Space

artículo científico publicado en 2017

Ultrastructural evidence for self-replication of Alzheimer-associated Aβ42 amyloid along the sides of fibrils

scientific article published on 21 May 2020

Lista de obras de Mikael Akke

15N NMR assignments and chemical shift analysis of uniformly labeled15N calbindin D9kin the apo, (Cd2+)1and (Ca2+)2states ⬇️

A De Novo Designed Coiled-Coil Peptide with a Reversible pH-Induced Oligomerization Switch

Adsorption of unfolded Cu/Zn superoxide dismutase onto hydrophobic surfaces catalyzes its formation of amyloid fibrils

Backbone H, C, and N resonance assignments of BoMan26A, a β-mannanase of the glycoside hydrolase family 26 from the human gut bacterium Bacteroides ovatus

Backbone H, C, and N resonance assignments of the ligand binding domain of the human wildtype glucocorticoid receptor and the F602S mutant variant

Backbone dynamics of calcium-loaded calbindin D9k studied by two-dimensional proton-detected 15N NMR spectroscopy

Chemical Shifts of the Carbohydrate Binding Domain of Galectin-3 from Magic Angle Spinning NMR and Hybrid Quantum Mechanics/Molecular Mechanics Calculations.

Computational design of a leucine-rich repeat protein with a predefined geometry

Conformational Entropies and Order Parameters: Convergence, Reproducibility, and Transferability

Conformational Entropy of FK506 Binding to FKBP12 Determined by Nuclear Magnetic Resonance Relaxation and Molecular Dynamics Simulations

Conformational dynamics and thermodynamics of protein–ligand binding studied by NMR relaxation ⬇️

Conserved S/T Residues of the Human Chaperone DNAJB6 Are Required for Effective Inhibition of Aβ42 Amyloid Fibril Formation

Cu/Zn Superoxide Dismutase Forms Amyloid Fibrils under Near-Physiological Quiescent Conditions: The Roles of Disulfide Bonds and Effects of Denaturant

Designing interactions by control of protein-ligand complex conformation: tuning arginine-arene interaction geometry for enhanced electrostatic protein-ligand interactions.

Dynamic allosteric communication pathway directing differential activation of the glucocorticoid receptor

Dynamics of Aromatic Side Chains in the Active Site of FKBP12.

Elucidation of hydrogen bonding patterns in ligand-free, lactose- and glycerol-bound galectin-3C by neutron crystallography to guide drug design.

From snapshot to movie: phi analysis of protein folding transition states taken one step further

Interplay between Conformational Entropy and Solvation Entropy in Protein-Ligand Binding

Local unfolding and aggregation mechanisms of SOD1: a Monte Carlo exploration.

Minute Additions of DMSO Affect Protein Dynamics Measurements by NMR Relaxation Experiments through Significant Changes in Solvent Viscosity

Molecular insights into substrate recognition and catalytic mechanism of the chaperone and FKBP peptidyl-prolyl isomerase SlyD

Nuclear magnetic resonance studies of the internal dynamics in Apo, (Cd2+)1 and (Ca2+)2 calbindin D9k. The rates of amide proton exchange with solvent

Off-resonance rotating-frame relaxation dispersion experiment for 13C in aromatic side chains using L-optimized TROSY-selection

Pervasive conformational fluctuations on microsecond time scales in a fibronectin type III domain

Protein conformational exchange measured by 1H R1ρ relaxation dispersion of methyl groups.

Rapid NMR Relaxation Measurements Using Optimal Nonuniform Sampling of Multidimensional Accordion Data Analyzed by a Sparse Reconstruction Method

Revealing Well-Defined Soluble States during Amyloid Fibril Formation by Multilinear Analysis of NMR Diffusion Data

Ring flips revisited: (13)C relaxation dispersion measurements of aromatic side chain dynamics and activation barriers in basic pancreatic trypsin inhibitor.

Rotamer Jumps, Proton Exchange, and Amine Inversion Dynamics of Dimethylated Lysine Residues in Proteins Resolved by pH-Dependent 1H and 13C NMR Relaxation Dispersion

Signal transduction versus buffering activity in Ca2+–binding proteins ⬇️

Slow aromatic ring flips detected despite near-degenerate NMR frequencies of the exchanging nuclei.

Solution Structure of (Cd2+)1-calbindin D9kReveals Details of the Stepwise Structural Changes along the Apo*rarr;(Ca2+)*rarr;(Ca)Binding Pathway ⬇️

Stability and Local Unfolding of SOD1 in the Presence of Protein Crowders

Starting-Condition Dependence of Order Parameters Derived from Molecular Dynamics Simulations.

Structural Analysis of a Complex between Small Ubiquitin-like Modifier 1 (SUMO1) and the ZZ Domain of CREB-binding Protein (CBP/p300) Reveals a New Interaction Surface on SUMO

Structural Insights into the Calcium-Mediated Allosteric Transition in the C-Terminal Domain of Calmodulin from Nuclear Magnetic Resonance Measurements.

Structural characterization of the microbial enzyme urocanate reductase mediating imidazole propionate production

Structural model of dodecameric heat-shock protein Hsp21: Flexible N-terminal arms interact with client proteins while C-terminal tails maintain the dodecamer and chaperone activity.

Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity

The Dynameomics Entropy Dictionary: A Large-Scale Assessment of Conformational Entropy across Protein Fold Space

Ultrastructural evidence for self-replication of Alzheimer-associated Aβ42 amyloid along the sides of fibrils

Solution Structure of (Cd2+)1-calbindin D9kReveals Details of the Stepwise Structural Changes along the Aporarr;(Ca2+)rarr;(Ca)Binding Pathway ⬇️