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Lista de obras de Iain McFadyen

A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates

artículo científico publicado en 2018

A sensitivity analysis of RNA folding nearest neighbor parameters identifies a subset of free energy parameters with the greatest impact on RNA secondary structure prediction

artículo científico publicado en 2017

Anthranilate 4H-oxazol-5-ones: novel small molecule antibacterial acyl carrier protein synthase (AcpS) inhibitors.

artículo científico publicado en 2004

Application of a High-Throughput Screening Procedure with PEG-Induced Precipitation to Compare Relative Protein Solubility During Formulation Development with IgG1 Monoclonal Antibodies

artículo científico publicado el 25 de octubre de 2010

Design of a high affinity peptidomimetic opioid agonist from peptide pharmacophore models.

artículo científico publicado en 1998

Exploring the unique pharmacology of a novel opioid receptor, ZFOR1, using molecular modeling and the 'message-address' concept.

artículo científico publicado en 2001

Human 5' UTR design and variant effect prediction from a massively parallel translation assay

scientific article published on 01 July 2019

Tetrapeptide derivatives of [D-Pen(2),D-Pen(5)]-enkephalin (DPDPE) lacking an N-terminal tyrosine residue are agonists at the mu-opioid receptor.

artículo científico publicado en 2000

The steroid 17alpha-acetoxy-6-dimethylaminomethyl-21-fluoro-3-ethoxy-pregna-3, 5-dien-20-one (SC17599) is a selective mu-opioid agonist: implications for the mu-opioid pharmacophore.

artículo científico publicado en 2000