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Lista de obras de Mary B Goldring

A cis-regulatory site downregulates PTHLH in translocation t(8;12)(q13;p11.2) and leads to Brachydactyly Type E.

artículo científico publicado en 2009

A hyaluronic acid-salmon calcitonin conjugate for the local treatment of osteoarthritis: chondro-protective effect in a rabbit model of early OA.

artículo científico publicado en 2014

A misplaced lncRNA causes brachydactyly in humans

artículo científico publicado en 2012

A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiation

scientific article published on 02 September 2005

ADAM17 controls endochondral ossification by regulating terminal differentiation of chondrocytes

artículo científico publicado en 2013

Activation of the discoidin domain receptor 2 induces expression of matrix metalloproteinase 13 associated with osteoarthritis in mice

artículo científico publicado en 2004

Angiopoietin-1 is expressed in the synovium of patients with rheumatoid arthritis and is induced by tumour necrosis factor alpha

artículo científico publicado en 2003

Articular Cartilage Degradation in Osteoarthritis

artículo científico publicado el 24 de enero de 2012

Articular cartilage and subchondral bone in the pathogenesis of osteoarthritis

artículo científico publicado en 2010

Association of reduced type IX collagen gene expression in human osteoarthritic chondrocytes with epigenetic silencing by DNA hypermethylation

artículo científico publicado en 2014

Bone and cartilage in osteoarthritis: is what's best for one good or bad for the other?

artículo científico publicado el 19 de octubre de 2010

C-28/I2 and T/C-28a2 chondrocytes as well as human primary articular chondrocytes express sex hormone and insulin receptors--Useful cells in study of cartilage metabolism

artículo científico publicado en 2010

CCAAT/enhancer binding protein β (C/EBPβ) regulates the transcription of growth arrest and DNA damage-inducible protein 45 β (GADD45β) in articular chondrocytes

artículo científico publicado en 2016

CITED2 mediates the cross-talk between mechanical loading and IL-4 to promote chondroprotection

scientific article published on 19 March 2019

CITED2 mediates the mechanical loading-induced suppression of adipokines in the infrapatellar fat pad

scientific article published on 19 March 2019

Cartilage homeostasis in health and rheumatic diseases

scientific article published on 19 May 2009

Cells of the synovium in rheumatoid arthritis. Chondrocytes

artículo científico publicado en 2007

Cellular responses to T-2 toxin and/or deoxynivalenol that induce cartilage damage are not specific to chondrocytes

artículo científico publicado en 2017

Changes in the osteochondral unit during osteoarthritis: structure, function and cartilage-bone crosstalk

artículo científico publicado en 2016

Clinical implications of cartilage metabolism in arthritis

artículo científico

Collagen XI mutation lowers susceptibility to load-induced cartilage damage in mice

artículo científico publicado en 2017

Correction to: Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse posttraumatic osteoarthritis model

scholarly article published in Arthritis Research and Therapy

Correction: Cells of the synovium in rheumatoid arthritis. Chondrocytes

scholarly article by Miguel Otero & Mary B Goldring published 16 January 2008 in Arthritis Research and Therapy

Cytokines

artículo científico publicado en 1988

DNA demethylation at specific CpG sites in the IL1B promoter in response to inflammatory cytokines in human articular chondrocytes

artículo científico publicado en 2009

DNA methylation of the RUNX2 P1 promoter mediates MMP13 transcription in chondrocytes

artículo científico publicado en 2017

Differential expression of GADD45beta in normal and osteoarthritic cartilage: potential role in homeostasis of articular chondrocytes.

artículo científico publicado en 2008

Differentiation regulates interleukin-1beta-induced cyclo-oxygenase-2 in human articular chondrocytes: role of p38 mitogen-activated protein kinase

artículo científico publicado en 2002

Dual proline labeling protocol for individual "baseline" and "response" biosynthesis measurements in human articular cartilage

artículo científico publicado en 2008

Dual regulation of metalloproteinase expression in chondrocytes by Wnt-1-inducible signaling pathway protein 3/CCN6.

artículo científico publicado en 2012

E74-Like Factor (ELF3) and Leptin, a Novel Loop Between Obesity and Inflammation Perpetuating a Pro-Catabolic State in Cartilage

artículo científico publicado en 2018

E74-like Factor 3 (ELF3) Impacts on Matrix Metalloproteinase 13 (MMP13) Transcriptional Control in Articular Chondrocytes under Proinflammatory Stress

artículo científico publicado el 9 de diciembre de 2011

E74-like factor 3 and nuclear factor-κB regulate lipocalin-2 expression in chondrocytes

artículo científico publicado en 2016

ELF3 modulates type II collagen gene (COL2A1) transcription in chondrocytes by inhibiting SOX9-CBP/p300-driven histone acetyltransferase activity

artículo científico publicado en 2016

ESE-1 is a novel transcriptional mediator of angiopoietin-1 expression in the setting of inflammation

artículo científico publicado en 2004

ESE-1 is a potent repressor of type II collagen gene (COL2A1) transcription in human chondrocytes

artículo científico publicado en 2008

Early knee osteoarthritis

artículo científico publicado en 2015

Eating bone or adding it: the Wnt pathway decides

scientific article published on 01 February 2007

Effects of pleiotrophin, a heparin-binding growth factor, on human primary and immortalized chondrocytes

scientific article published on 01 September 2006

Egr-1 mediates transcriptional repression of COL2A1 promoter activity by interleukin-1beta

artículo científico publicado en 2003

Elf3 Contributes to Cartilage Degradation in vivo in a Surgical Model of Post-Traumatic Osteoarthritis

artículo científico publicado en 2018

Emerging targets in osteoarthritis therapy.

artículo científico publicado en 2015

Endostatin/collagen XVIII--an inhibitor of angiogenesis--is expressed in cartilage and fibrocartilage

artículo científico publicado en 2004

Epigenomic and microRNA-mediated regulation in cartilage development, homeostasis, and osteoarthritis

artículo científico publicado el 17 de diciembre de 2011

Evaluation of surfactant proteins A, B, C, and D in articular cartilage, synovial membrane and synovial fluid of healthy as well as patients with osteoarthritis and rheumatoid arthritis

artículo científico publicado en 2018

Expression and regulation of human beta-defensin-2 in osteoarthritic cartilage

artículo científico publicado en 2006

GADD45beta enhances Col10a1 transcription via the MTK1/MKK3/6/p38 axis and activation of C/EBPbeta-TAD4 in terminally differentiating chondrocytes

artículo científico publicado en 2010

Generation of collagenase-resistant collagen by site-directed mutagenesis of murine pro alpha 1(I) collagen gene

artículo científico publicado en 1990

Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse post-traumatic osteoarthritis model.

artículo científico publicado en 2014

Homeostatic mechanisms in articular cartilage and role of inflammation in osteoarthritis

artículo científico publicado en 2013

Hsp70 accumulation in chondrocytic cells exposed to high continuous hydrostatic pressure coincides with mRNA stabilization rather than transcriptional activation

artículo científico publicado en 1998

Human beta-defensin 3 mediates tissue remodeling processes in articular cartilage by increasing levels of metalloproteinases and reducing levels of their endogenous inhibitors

artículo científico publicado en 2005

Human chondrocyte cultures as models of cartilage-specific gene regulation

scientific article published on 01 January 2012

Human chondrocyte cultures as models of cartilage-specific gene regulation.

artículo científico publicado en 1996

IKKα/CHUK regulates extracellular matrix remodeling independent of its kinase activity to facilitate articular chondrocyte differentiation.

artículo científico publicado en 2013

Immune interferon suppresses levels of procollagen mRNA and type II collagen synthesis in cultured human articular and costal chondrocytes

scientific article published on 01 July 1986

In vivo cyclic compression causes cartilage degeneration and subchondral bone changes in mouse tibiae

artículo científico publicado en 2013

Increased expression of the collagen receptor discoidin domain receptor 2 in articular cartilage as a key event in the pathogenesis of osteoarthritis

artículo científico publicado en 2007

Individual and combined toxicity of T-2 toxin and deoxynivalenol on human C-28/I2 and rat primary chondrocytes

article

Inducible knockout of CHUK/IKKα in adult chondrocytes reduces progression of cartilage degradation in a surgical model of osteoarthritis.

artículo científico publicado en 2019

Inflammation in osteoarthritis

scientific article published on September 2011

Inflammatory molecules produced by meniscus and synovium in early and end-stage osteoarthritis: a coculture study

artículo científico publicado en 2018

Intact Pericellular Matrix of Articular Cartilage Is Required for Unactivated Discoidin Domain Receptor 2 in the Mouse Model

artículo científico publicado el 1 de septiembre de 2011

Interleukin 1 suppresses expression of cartilage-specific types II and IX collagens and increases types I and III collagens in human chondrocytes

artículo científico publicado en 1988

Interleukin-1 beta-modulated gene expression in immortalized human chondrocytes

artículo científico publicado en 1994

Is arthroscopic videotape a reliable tool for describing early joint tissue pathology of the knee?

artículo científico publicado en 2017

Kinematics of meniscal- and ACL-transected mouse knees during controlled tibial compressive loading captured using roentgen stereophotogrammetry

artículo científico publicado en 2016

Labral calcification plays a key role in hip pain and symptoms in femoroacetabular impingement

scientific article published on 28 February 2020

Lack of ADAM10 in endothelial cells affects osteoclasts at the chondro-osseus junction

artículo científico

Laminins and Nidogens in the Pericellular Matrix of Chondrocytes: Their Role in Osteoarthritis and Chondrogenic Differentiation

artículo científico publicado en 2015

Loss of methylation in CpG sites in the NF-κB enhancer elements of inducible nitric oxide synthase is responsible for gene induction in human articular chondrocytes.

artículo científico publicado en 2013

Mechanical forces induce changes in VEGF and VEGFR-1/sFlt-1 expression in human chondrocytes.

artículo científico publicado en 2014

Mechanisms of matrix degradation in rheumatoid arthritis

artículo científico publicado en 1990

Mitochondrial DNA haplogroups and ageing mechanisms in osteoarthritis

artículo científico publicado en 2017

Modulation by recombinant interleukin 1 of synthesis of types I and III collagens and associated procollagen mRNA levels in cultured human cells

artículo científico publicado en 1987

Morphological and ultrastructural analysis of normal, injured and osteoarthritic human knee menisci

artículo científico publicado en 2019

Mouse Models of Osteoarthritis: Surgical Model of Post-traumatic Osteoarthritis Induced by Destabilization of the Medial Meniscus

artículo científico publicado en 2021

Mouse models of osteoarthritis: surgical model of posttraumatic osteoarthritis induced by destabilization of the medial meniscus

artículo científico publicado en 2015

NF-kappaB signaling: multiple angles to target OA.

scientific article published on May 2010

NF-κB-mediated repression of growth arrest- and DNA-damage-inducible proteins 45α and γ is essential for cancer cell survival

artículo científico publicado en 2004

Osteoarthritis

article by Johanne Martel-Pelletier et al published 13 October 2016 in Nature Reviews Disease Primers

Osteoarthritis

scientific article published on 01 December 2007

Osteoarthritis: a disease of the joint as an organ

artículo científico publicado en 2012

Pathophysiology of osteoarthritis: canonical NF-κB/IKKβ-dependent and kinase-independent effects of IKKα in cartilage degradation and chondrocyte differentiation

artículo científico publicado en 2015

Perlecan is required for the chondrogenic differentiation of synovial mesenchymal cells through regulation of Sox9 gene expression

artículo científico publicado en 2016

Phenotypic instability of chondrocytes in osteoarthritis: on a path to hypertrophy

artículo científico publicado en 2018

Phlpp inhibitors block pain and cartilage degradation associated with osteoarthritis

artículo científico publicado en 2017

Polyamine depletion inhibits NF-kappaB binding to DNA and interleukin-8 production in human chondrocytes stimulated by tumor necrosis factor-alpha.

artículo científico publicado en 2005

Polyamine depletion inhibits apoptosis following blocking of survival pathways in human chondrocytes stimulated by tumor necrosis factor-alpha

artículo científico publicado en 2006

Potential role for interleukin-1 in fibrosis associated with chronic ambulatory peritoneal dialysis

artículo científico publicado en 1988

Preparation of Immortalized Human Chondrocyte Cell Lines

artículo científico publicado el 1 de enero de 1999

Production of endogenous antibiotics in articular cartilage.

artículo científico publicado en 2004

Progressive cell-mediated changes in articular cartilage and bone in mice are initiated by a single session of controlled cyclic compressive loading

artículo científico publicado en 2016

Proteomic Analysis of Synovial Fluid From the Osteoarthritic Knee: Comparison With Transcriptome Analyses of Joint Tissues

artículo científico publicado el 1 de abril de 2013

Reactive oxygen species induce expression of vascular endothelial growth factor in chondrocytes and human articular cartilage explants

artículo científico publicado en 2006

Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites

artículo científico publicado en 2013

Relationship between cartilage stiffness and dGEMRIC index: correlation and prediction

artículo científico publicado en 2007

Response to "Letter to the editor: Labral calcification plays a key role in hip pain and symptoms in femoroacetabular impingement"

artículo científico publicado en 2020

Responses to the proinflammatory cytokines interleukin-1 and tumor necrosis factor alpha in cells derived from rheumatoid synovium and other joint tissues involve nuclear factor kappaB-mediated induction of the Ets transcription factor ESE-1.

artículo científico publicado en 2003

Role of subchondral bone properties and changes in development of load-induced osteoarthritis in mice

artículo científico publicado en 2017

Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis

artículo científico publicado el 24 de febrero de 2011

Selenium promotes metabolic conversion of T-2 toxin to HT-2 toxin in cultured human chondrocytes

artículo científico publicado en 2017

Senescence of chondrocytes in aging articular cartilage: GADD45β mediates p21 expression in association with C/EBPβ in senescence-accelerated mice

artículo científico publicado el 24 de febrero de 2011

Skeletal tissue response to cytokines

artículo científico

Stimulation of procollagenase synthesis parallels increases in cellular procollagenase mRNA in human articular chondrocytes exposed to recombinant interleukin 1 beta or phorbol ester.

artículo científico publicado en 1987

Strain-induced mechanotransduction through primary cilia, extracellular ATP, purinergic calcium signaling, and ERK1/2 transactivates CITED2 and downregulates MMP-1 and MMP-13 gene expression in chondrocytes.

artículo científico publicado en 2015

Suppression of type I collagen gene expression by prostaglandins in fibroblasts is mediated at the transcriptional level

artículo científico publicado en 2000

Suppressors of cytokine signalling (SOCS) are reduced in osteoarthritis.

artículo científico publicado en 2011

Susceptibility of type I collagen containing mutated alpha 1(1) chains to cleavage by human neutrophil collagenase.

artículo científico publicado en 1993

T cell-specific expression of the murine CD3delta promoter

artículo científico publicado en 2002

TLR-2-mediated induction of vascular endothelial growth factor (VEGF) in cartilage in septic joint disease

artículo científico publicado en 2006

The Ets transcription factor ESE-1 mediates induction of the COX-2 gene by LPS in monocytes

scientific article published on 01 April 2005

The TATA-containing core promoter of the type II collagen gene (COL2A1) is the target of interferon-gamma-mediated inhibition in human chondrocytes: requirement for Stat1 alpha, Jak1 and Jak2.

artículo científico publicado en 2003

The control of chondrogenesis

artículo científico publicado en 2006

The effect of paraformaldehyde fixation on the delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) measurement

artículo científico publicado en 2009

The epigenetic effect of glucosamine and a nuclear factor-kappa B (NF-kB) inhibitor on primary human chondrocytes--implications for osteoarthritis

artículo científico publicado en 2011

The integrative analysis of DNA methylation and mRNA expression profiles confirmed the role of selenocompound metabolism pathway in Kashin-Beck disease

artículo científico publicado en 2020

The role of cytokines in cartilage matrix degeneration in osteoarthritis.

artículo científico publicado en 2004

Transcriptomic and epigenomic analyses uncovered Lrrc15 as a contributing factor to cartilage damage in osteoarthritis

artículo científico publicado en 2021

Trefoil factor 3 is induced during degenerative and inflammatory joint disease, activates matrix metalloproteinases, and enhances apoptosis of articular cartilage chondrocytes.

artículo científico publicado en 2010

Tribute to Stephen M. Krane

artículo científico publicado en 2015

Up-regulation of microsomal prostaglandin E synthase 1 in osteoarthritic human cartilage: critical roles of the ERK-1/2 and p38 signaling pathways

artículo científico publicado en 2004

VEGF expression in adult permanent thyroid cartilage: implications for lack of cartilage ossification

artículo científico publicado en 2004

Vascular endothelial growth factor (VEGF) induces matrix metalloproteinase expression in immortalized chondrocytes

artículo científico publicado en 2004