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Lista de obras de David W. Hein

2-Amino-3,8-dimethylimidazo-[4,5-f]quinoxaline-induced DNA adduct formation and mutagenesis in DNA repair-deficient Chinese hamster ovary cells expressing human cytochrome P4501A1 and rapid or slow acetylator N-acetyltransferase 2

artículo científico publicado en 2007

2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine-induced DNA adducts and genotoxicity in chinese hamster ovary (CHO) cells expressing human CYP1A2 and rapid or slow acetylator N-acetyltransferase 2.

artículo científico publicado en 2007

4,4'-methylenedianiline-induced hepatotoxicity is modified by N-acetyltransferase 2 (NAT2) acetylator polymorphism in the rat

scientific journal article

4-Aminobiphenyl downregulation of NAT2 acetylator genotype-dependent N- and O-acetylation of aromatic and heterocyclic amine carcinogens in primary mammary epithelial cell cultures from rapid and slow acetylator rats

artículo científico publicado en 2008

560G>A (rs4986782) (R187Q) Single Nucleotide Polymorphism in Arylamine N-Acetyltransferase 1 Increases Affinity for the Aromatic Amine Carcinogens 4-Aminobiphenyl and N-Hydroxy-4-Aminobiphenyl: Implications for Cancer Risk Assessment

A Restriction Fragment Length Polymorphism Assay That Differentiates HumanN-Acetyltransferase-1 (NAT1) Alleles ⬇️

artículo científico publicado el 15 de noviembre de 1997

A flexible route to chiral 2-endo-substituted 9-oxabispidines and their application in the enantioselective oxidation of secondary alcohols.

artículo científico publicado en 2009

A single nucleotide polymorphism tags variation in the arylamine N-acetyltransferase 2 phenotype in populations of European background

artículo científico publicado en 2011

Accuracy of various human NAT2 SNP genotyping panels to infer rapid, intermediate and slow acetylator phenotypes

artículo científico publicado en 2011

Acetyl CoA:arylamine N-acetyltransferase activity in rat hepatocytes cultured on different extracellular matrices.

artículo científico publicado en 1997

Acetyl coenzyme A kinetic studies on -acetylation of environmental carcinogens by human -acetyltransferase 1 and its variant

Acetylation of putative arylamine and alkylaniline carcinogens in immortalized human fibroblasts transfected with rapid and slow acetylator N-acetyltransferase 2 haplotypes

artículo científico publicado en 2020

Acetylator Genotype-Dependent Dyslipidemia in Rats Congenic for N-Acetyltransferase 2

artículo científico publicado en 2020

Acetylator phenotype and genotype in HIV-infected patients with and without sulfonamide hypersensitivity

artículo científico publicado en 2002

Acetylator phenotype-dependent and -independent expression of arylamine N-acetyltransferase isozymes in rapid and slow acetylator inbred rat liver ⬇️

artículo científico publicado el 1 de septiembre de 1991

Acetyltransferases and susceptibility to chemicals

artículo científico publicado el 1 de diciembre de 1992

An alternative cyclin-D1 splice site is not linked to inflammatory bowel disease-associated neoplasia

artículo científico publicado en 2010

Arylamine -Acetyltransferase 1 Activity is Regulated by the Protein Acetylation Status

Arylamine N-acetyltransferase 1 in situ N-acetylation on CD3+ peripheral blood mononuclear cells correlate with NATb mRNA and NAT1 haplotype

artículo científico publicado en 2017

Arylamine N-acetyltransferase 2 genotype-dependent N-acetylation of isoniazid in cryopreserved human hepatocytes.

artículo científico publicado en 2017

Arylamine N-acetyltransferase acetylation polymorphisms: paradigm for pharmacogenomic-guided therapy- a focused review

artículo científico publicado en 2020

Association between cigarette smoking and ovarian reserve among women seeking fertility care

Association between manganese superoxide dismutase promoter gene polymorphism and breast cancer survival

artículo científico publicado en 2006

Association of metabolic gene polymorphisms with tobacco consumption in healthy controls

artículo científico publicado en 2004

Association of prostate cancer with rapid N-acetyltransferase 1 (NAT1*10) in combination with slow N-acetyltransferase 2 acetylator genotypes in a pilot case-control study

artículo científico publicado en 2002

Association of the histamine N-methyltransferase C314T (Thr105Ile) polymorphism with atopic dermatitis in Caucasian children

artículo científico publicado en 2008

Bioactivation, protein haptenation, and toxicity of sulfamethoxazole and dapsone in normal human dermal fibroblasts

artículo científico publicado en 2006

CRISPR/Cas9 knockout of human arylamine N-acetyltransferase 1 in MDA-MB-231 breast cancer cells suggests a role in cellular metabolism

scientific article published on 17 June 2020

Catalytic properties and heat stabilities of novel recombinant human N-acetyltransferase 2 allozymes support existence of genetic heterogeneity within the slow acetylator phenotype

artículo científico publicado en 2017

Changes in consensus arylamine N-acetyltransferase gene nomenclature

artículo científico publicado en 2008

Characterization of N-acetyltransferase 1 and 2 polymorphisms and haplotype analysis for inflammatory bowel disease and sporadic colorectal carcinoma

artículo científico publicado en 2007

Chemoprevention of arylamine-induced colorectal aberrant crypts

artículo científico publicado en 2008

Chemopreventive drug treatment in subjects with genetic predisposition to cancer: prescriber liability and healthcare disparities

artículo científico publicado en 2004

Chiral 2-endo-substituted 9-oxabispidines: novel ligands for enantioselective copper(II)-catalyzed Henry reactions.

artículo científico publicado en 2009

Cigarette smoking, N-acetyltransferase genes and the risk of advanced colorectal adenoma

artículo científico publicado en 2006

Clinical Pharmacokinetics of Isoniazid

artículo científico publicado el 1 de noviembre de 1979

Clinical pharmacogenetics in pediatric patients

artículo científico publicado en 2007

Codominant expression of N-acetylation and O-acetylation activities catalyzed by N-acetyltransferase 2 in human hepatocytes

artículo científico publicado en 2010

Commentary: Reflections on G. M. Lower and colleagues' 1979 study associating slow acetylator phenotype with urinary bladder cancer: meta-analysis, historical refinements of the hypothesis, and lessons learned

artículo científico publicado en 2007

Computational and experimental analyses of mammalian arylamine N-acetyltransferase structure and function

artículo científico publicado en 2007

Congenic rats with higher arylamine N-acetyltransferase 2 activity exhibit greater carcinogen-induced mammary tumor susceptibility independent of carcinogen metabolism.

artículo científico publicado en 2017

Controlling incision-induced distortion of nasal septal cartilage: a model to predict the effect of scoring of rabbit septa

scientific article published on 01 May 2003

Daily Rhythm in Plasma N-acetyltryptamine.

artículo científico publicado en 2017

Dataset for proteomic analysis of arylamine -acetyltransferase 1 knockout MDA-MB-231 breast cancer cells

Dehydroepiandrosterone Activation of G-protein-coupled Estrogen Receptor Rapidly Stimulates MicroRNA-21 Transcription in Human Hepatocellular Carcinoma Cells

artículo científico publicado en 2015

Deletion of arylamine N-acetyltransferase 1 in MDA-MB-231 human breast cancer cells reduces primary and secondary tumor growth in vivo with no significant effects on metastasis

Design and Success of a 21st Century Cancer Education Program at the University of Louisville

artículo científico publicado en 2016

Differences between human slow N-acetyltransferase 2 alleles in levels of 4-aminobiphenyl-induced DNA adducts and mutations

scientific article published on 12 August 2009

Differences in β-naphthylamine metabolism and toxicity in Chinese hamster ovary cell lines transfected with human CYP1A2 and NAT2*4, NAT2*5B or NAT2*7B N-acetyltransferase 2 haplotypes

Dose-dependent reduction of 3,2'-dimethyl-4-aminobiphenyl-derived DNA adducts in colon and liver of rats administered celecoxib

artículo científico publicado en 2007

Effect of N-acetyltransferase 2 genetic polymorphism on 4,4'-methylenebis(2-chloroaniline)-induced genotoxicity and oxidative stress

Effect of N-acetyltransferase 2 polymorphism on tumor target tissue DNA adduct levels in rapid and slow acetylator congenic rats administered 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine or 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline

artículo científico publicado en 2009

Effect of nucleotide substitutions in N-acetyltransferase-1 on N-acetylation (deactivation) and O-acetylation (activation) of arylamine carcinogens: implications for cancer predisposition

artículo científico publicado en 2002

Effect of rapid human N-acetyltransferase 2 haplotype on DNA damage and mutagenesis induced by 2-amino-3-methylimidazo-[4,5-f]quinoline (IQ) and 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline (MeIQx).

artículo científico publicado en 2009

Effects of dietary factors and the NAT2 acetylator status on gastric cancer in Koreans.

artículo científico publicado en 2009

Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity

Effects of single nucleotide polymorphisms in human N-acetyltransferase 2 on metabolic activation (O-acetylation) of heterocyclic amine carcinogens

artículo científico publicado en 2006

Etiologic heterogeneity among non-Hodgkin lymphoma subtypes

artículo científico publicado en 2008

Evaluation of Oxidative Stress Response Related Genetic Variants, Pro-oxidants, Antioxidants and Prostate Cancer

artículo científico publicado en 2015

Evidence for an intensity-dependent interaction of NAT2 acetylation genotype and cigarette smoking in the Spanish Bladder Cancer Study

article

Examination of polymorphic glutathione S-transferase (GST) genes, tobacco smoking and prostate cancer risk among men of African descent: a case-control study

artículo científico publicado en 2009

Expression and genotype-dependent catalytic activity of N-acetyltransferase 2 (NAT2) in human peripheral blood mononuclear cells and its modulation by Sirtuin 1

scientific article published on 25 August 2018

Expression of arylamine N-acetyltransferase 2 activity in immortalized human bronchial epithelial cells

Folate-Dependent Hydrolysis of Acetyl-Coenzyme A by Recombinant Human and Rodent Arylamine N-Acetyltransferases

artículo científico publicado en 2015

Functional analysis of arylamine N-acetyltransferase 1 (NAT1) NAT1*10 haplotypes in a complete NATb mRNA construct.

artículo científico publicado en 2011

Functional analysis of arylamine N-acetyltransferase 1 (NAT1) haplotypes in a complete NATb mRNA construct

Functional analysis of the human N-acetyltransferase 1 major promoter: quantitation of tissue expression and identification of critical sequence elements.

artículo científico publicado en 2007

Functional characterization of single-nucleotide polymorphisms and haplotypes of human N-acetyltransferase 2.

artículo científico publicado en 2007

Functional characterization of the A411T (L137F) and G364A (D122N) genetic polymorphisms in human N-acetyltransferase 2.

artículo científico publicado en 2007

Functional effects of genetic polymorphisms in the N-acetyltransferase 1 coding and 3' untranslated regions

artículo científico publicado en 2011

Functional expression of human arylamine N-acetyltransferase NAT1*10 and NAT1*11 alleles: a mini review

scientific article published on 01 October 2018

Functional genomics of C190T single nucleotide polymorphism in human N-acetyltransferase 2.

artículo científico publicado en 2002

Functional properties of an alternative, tissue-specific promoter for human arylamine N-acetyltransferase 1

artículo científico publicado en 2006

GSTM1 null genotype, red meat consumption and breast cancer risk (The Netherlands).

artículo científico publicado en 2004

Genetic and small molecule inhibition of arylamine N-acetyltransferase 1 reduces anchorage-independent growth in human breast cancer cell line MDA-MB-231.

artículo científico publicado en 2018

Genetic heterogeneity among slow acetylator N-acetyltransferase 2 phenotypes in cryopreserved human hepatocytes

artículo científico publicado en 2017

Genetic polymorphisms in heterocyclic amine metabolism and risk of colorectal adenomas

artículo científico publicado en 2002

Genetic profiling of colon cancer

artículo científico publicado en 2002

Genetic regulation of N-acetyltransferase in target organs of arylamine tumors: homologous expression in human and hamster bladder and colon

artículo científico publicado el 1 de enero de 1991

Genetic variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2) and risk of non-Hodgkin lymphoma

artículo científico publicado en 2006

Genetic variation in N-acetyltransferases 1 and 2, cigarette smoking, and risk of non-Hodgkin lymphoma

artículo científico publicado en 2009

Hair dye use and risk of bladder cancer in the New England bladder cancer study

artículo científico publicado en 2011

Hair dye use, genetic variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2), and risk of non-Hodgkin lymphoma

artículo científico publicado en 2007

Haplotype of N-acetyltransferase 1 and 2 and risk of pancreatic cancer

artículo científico publicado en 2007

Hemoglobin adduct and hepatic- and urinary bladder-DNA adduct levels in rapid and slow acetylator Syrian inbred hamsters administered 2-aminofluorene ⬇️

artículo científico publicado el 1 de febrero de 1992

Heterocyclic amines reduce insulin-induced AKT phosphorylation and induce gluconeogenic gene expression in human hepatocytes

Hexavalent chromium increases the metabolism and genotoxicity of aromatic amine carcinogens 4-aminobiphenyl and β-naphthylamine in immortalized human lung epithelial cells

High N-acetyltransferase 1 (NAT1) expression is associated with estrogen receptor expression in breast tumors, but is not under direct regulation by estradiol, 17beta-diol, or dihydrotestosterone in breast cancer cells

artículo científico publicado en 2018

Human -Acetyltransferase 1 and 2 Differ in Affinity Towards Acetyl-Coenzyme A Cofactor and -Hydroxy-Arylamine Carcinogens

Human Arylamine <i>N</i>-Acetyltransferase 1 (NAT1) Knockout in MDA-MB-231 Breast Cancer Cell Lines Leads to Transcription of NAT2

artículo científico publicado en 2021

Human arylamine N-acetyltransferase 2 genotype-dependent protein expression in cryopreserved human hepatocytes

artículo científico publicado en 2020

Identification and characterization of functional rat arylamine N-acetyltransferase 3: comparisons with rat arylamine N-acetyltransferases 1 and 2.

artículo científico publicado en 2006

Identification and characterization of potent, selective, and efficacious inhibitors of human arylamine N-acetyltransferase 1

Identification of N-acetyltransferase 2 (NAT2) transcription start sites and quantitation of NAT2-specific mRNA in human tissues.

artículo científico publicado en 2007

Identification of the major promoter and non-coding exons of the human arylamine N-acetyltransferase 1 gene (NAT1).

artículo científico publicado en 2004

Impact of misclassification in genotype-exposure interaction studies: example of N-acetyltransferase 2 (NAT2), smoking, and bladder cancer.

artículo científico publicado en 2004

In Memoriam: Wendell W. Weber, PhD, MD (1925-2018)

artículo científico publicado en 2018

Inactivation of GSK-3beta by metallothionein prevents diabetes-related changes in cardiac energy metabolism, inflammation, nitrosative damage, and remodeling

artículo científico publicado en 2009

Inducible nitric oxide synthase is required in alcohol-induced liver injury: studies with knockout mice

artículo científico publicado en 2003

Induction of glucose production by heterocyclic amines is dependent on N-acetyltransferase 2 genetic polymorphism in cryopreserved human hepatocytes

Interaction among apoptosis-associated sequence variants and joint effects on aggressive prostate cancer.

artículo científico publicado en 2012

Interaction of cigarette smoking and carcinogen-metabolizing polymorphisms in the risk of colorectal polyps

artículo científico publicado en 2013

Interaction of the cytochrome P4501A2, SULT1A1 and NAT gene polymorphisms with smoking and dietary mutagen intake in modification of the risk of pancreatic cancer

artículo científico publicado en 2008

Knockout of human arylamine N-acetyltransferase 1 (NAT1) in MDA-MB-231 breast cancer cells leads to increased reserve capacity, maximum mitochondrial capacity, and glycolytic reserve capacity

artículo científico publicado en 2018

Lack of association of the N-acetyltransferase NAT1*10 allele with prostate cancer incidence, grade, or stage among smokers in Finland

artículo científico publicado en 2010

METHODS FOR AROMATIC AND HETEROCYCLIC AMINE CARCINOGEN-DNA ADDUCT ANALYSIS BY LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY.

artículo científico publicado en 2008

Manganese superoxide dismutase V16A single-nucleotide polymorphism in the mitochondrial targeting sequence is associated with reduced enzymatic activity in cryopreserved human hepatocytes

artículo científico publicado en 2009

Manganese superoxide dismutase expression as a function of genotype and lung cancer pathology

artículo científico publicado en 2010

Manganese superoxide dismutase gene coding region polymorphisms lack clinical incidence in general population

artículo científico publicado en 2008

Meat intake, heterocyclic amine exposure, and metabolizing enzyme polymorphisms in relation to colorectal polyp risk

artículo científico publicado en 2008

Metabolic activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Syrian hamsters congenic at the N-acetyltransferase 2 (NAT2) locus

artículo científico publicado en 2003

Metallothionein suppresses angiotensin II-induced nicotinamide adenine dinucleotide phosphate oxidase activation, nitrosative stress, apoptosis, and pathological remodeling in the diabetic heart.

artículo científico publicado en 2008

Method for determination of (-102C>T) single nucleotide polymorphism in the human manganese superoxide dismutase promoter

artículo científico publicado en 2004

Molecular genetics and function of NAT1 and NAT2: role in aromatic amine metabolism and carcinogenesis

artículo científico publicado en 2002

Mouse arylamine N-acetyltransferase 2 (Nat2) expression during embryogenesis: a potential marker for the developing neuroendocrine system.

artículo científico publicado en 2008

N-Acetyltransferase 1 Knockout Elevates Acetyl Coenzyme A Levels and Reduces Anchorage-Independent Growth in Human Breast Cancer Cell Lines

artículo científico publicado en 2019

N-Acetyltransferase 2 Genotype-Dependent N-Acetylation of Hydralazine in Human Hepatocytes

artículo científico publicado en 2017

N-acetyltransferase (NAT1, NAT2) and glutathione S-transferase (GSTM1, GSTT1) polymorphisms in breast cancer

artículo científico publicado en 2003

N-acetyltransferase (Nat) 1 and 2 expression in Nat2 knockout mice

artículo científico publicado en 2006

N-acetyltransferase 2 acetylator genotype-dependent N-acetylation and toxicity of the arylamine carcinogen β-naphthylamine in cryopreserved human hepatocytes

N-acetyltransferase 2 acetylator genotype-dependent N-acetylation of 4-aminobiphenyl in cryopreserved human hepatocytes

artículo científico publicado en 2020

N-acetyltransferase 2 genetic polymorphism modifies genotoxic and oxidative damage from new psychoactive substances

N-acetyltransferase 2 genotype modification of active cigarette smoking on breast cancer risk among hispanic and non-hispanic white women.

artículo científico publicado en 2009

N-acetyltransferase 2 haplotype modifies risks for both dyslipidemia and urinary bladder cancer

N-acetyltransferase SNPs: emerging concepts serve as a paradigm for understanding complexities of personalized medicine

artículo científico publicado en 2009

NAT2 slow acetylation and GSTM1 null genotypes may increase postmenopausal breast cancer risk in long-term smoking women

artículo científico publicado en 2003

NAT2 slow acetylation, GSTM1 null genotype, and risk of bladder cancer: results from the Spanish Bladder Cancer Study and meta-analyses

artículo científico publicado en 2005

NATb/NAT1*4 promotes greater arylamine N-acetyltransferase 1 mediated DNA adducts and mutations than NATa/NAT1*4 following exposure to 4-aminobiphenyl

artículo científico publicado en 2011

Narcotic drug discriminations by rhesus monkeys and pigeons

artículo científico publicado el 1 de enero de 1979

No apparent association between NAT1 and NAT2 genotypes and risk of stomach cancer

artículo científico publicado en 2003

No apparent association between genetic polymorphisms (-102 C>T) and (-9 T>C) in the human manganese superoxide dismutase gene and gastric cancer(1).

artículo científico publicado en 2005

No association between variant N-acetyltransferase genes, cigarette smoking and Prostate Cancer susceptibility among men of African descent

artículo científico publicado en 2011

Nomenclature for N-acetyltransferases

artículo científico publicado en 1995

Non-coding and intergenic genetic variants of human arylamine -acetyltransferase 2 (NAT2) gene are associated with differential plasma lipid and cholesterol levels and cardiometabolic disorders

Permanent hair dyes and bladder cancer: risk modification by cytochrome P4501A2 and N-acetyltransferases 1 and 2.

artículo científico publicado en 2003

PharmGKB summary: very important pharmacogene information for N-acetyltransferase 2

artículo científico publicado en 2014

Phenotype of the most common "slow acetylator" arylamine N-acetyltransferase 1 genetic variant (NAT1*14B) is substrate-dependent

artículo científico publicado en 2011

Polymorphic N-acetylation of phenelzine and monoacetylhydrazine by highly purified rabbit liver isoniazid N-acetyltransferase ⬇️

artículo científico publicado el 1 de mayo de 1982

Polymorphic genes of detoxification and mitochondrial enzymes and risk for progressive supranuclear palsy: a case control study

artículo científico publicado en 2012

Polymorphisms of cytochrome P4501A2 and N-acetyltransferase genes, smoking, and risk of pancreatic cancer

artículo científico publicado en 2005

Projected changes in tropical cyclones over Vietnam and the South China Sea using a 25 km regional climate model perturbed physics ensemble

article

Prostate expression of N-acetyltransferase 1 (NAT1) and 2 (NAT2) in rapid and slow acetylator congenic Syrian hamster

artículo científico publicado en 2003

Proteomic analysis of arylamine -acetyltransferase 1 knockout breast cancer cells: Implications in immune evasion and mitochondrial biogenesis

Quantitative tissue and gene-specific differences and developmental changes in Nat1, Nat2, and Nat3 mRNA expression in the rat

scientific journal article

Rabbit N-acetyltransferase 2 genotyping method to investigate role of acetylation polymorphism on N- and O-acetylation of aromatic and heterocyclic amine carcinogens

artículo científico publicado en 2017

Rapid genotype method to distinguish frequent and/or functional polymorphisms in human N-acetyltransferase-1

artículo científico publicado en 2002

Reduced 4-aminobiphenyl-induced liver tumorigenicity but not DNA damage in arylamine N-acetyltransferase null mice

artículo científico publicado en 2011

Relationship between N-acetyltransferase 2 single-nucleotide polymorphisms and phenotype

artículo científico publicado en 2009

Retrospective analysis of estrogen receptor 1 and N‑acetyltransferase gene expression in normal breast tissue, primary breast tumors, and established breast cancer cell lines.

artículo científico publicado en 2018

Role of Human N-Acetyltransferase 2 Genetic Polymorphism on Aromatic Amine Carcinogen-Induced DNA Damage and Mutagenicity in a Chinese Hamster Ovary Cell Mutation Assay

scientific article published on 30 September 2019

Role of N-acetyltransferase 2 acetylation polymorphism in 4, 4'-methylene bis (2-chloroaniline) biotransformation

artículo científico publicado en 2017

Role of the N-acetylation polymorphism in solithromycin metabolism.

artículo científico publicado en 2017

Role of the human N-acetyltransferase 2 genetic polymorphism in metabolism and genotoxicity of 4, 4'-methylenedianiline

scientific article published on 10 July 2019

Role of the renin-angiotensin system in hepatic ischemia reperfusion injury in rats

artículo científico publicado en 2004

Simultaneous determination of 7 N-acetyltransferase-2 single-nucleotide variations by allele-specific primer extension assay

artículo científico

Smoking, variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2), and risk of non-Hodgkin lymphoma: a pooled analysis within the InterLymph consortium

artículo científico publicado en 2012

Stable Isotope Tracing Reveals an Altered Fate of Glucose in -Acetyltransferase 1 Knockout Breast Cancer Cells

Structure-function analyses of single nucleotide polymorphisms in human N-acetyltransferase 1

artículo científico publicado en 2008

Structure/function evaluations of single nucleotide polymorphisms in human N-acetyltransferase 2

artículo científico publicado en 2008

Systemic functional expression of N-acetyltransferase polymorphism in the F344 Nat2 congenic rat.

artículo científico publicado en 2008

TaqMan real time-polymerase chain reaction methods for determination of nucleotide polymorphisms in human N-acetyltransferase-1 (NAT1) and -2 (NAT2)

artículo científico publicado en 2005

The T341C (Ile114Thr) polymorphism of N-acetyltransferase 2 yields slow acetylator phenotype by enhanced protein degradation

artículo científico publicado en 2004

The impact of NAT2 acetylator genotype on mutagenesis and DNA adducts from 2-amino-9H-pyrido[2,3-b]indole

artículo científico publicado en 2009

Tissue distribution of N-acetyltransferase 1 and 2 catalyzing the N-acetylation of 4-aminobiphenyl and O-acetylation of N-hydroxy-4-aminobiphenyl in the congenic rapid and slow acetylator Syrian hamster

artículo científico publicado en 2006

Tissue expression and genomic sequences of rat N-acetyltransferases rNat1, rNat2, rNat3, and Functional characterization of a novel rNat3*2 genetic variant

artículo científico publicado en 2007

Transcriptional Regulation of Human Arylamine N-Acetyltransferase 2 Gene by Glucose and Insulin in Liver Cancer Cell Lines

Untargeted polar metabolomics of transformed MDA-MB-231 breast cancer cells expressing varying levels of human arylamine N-acetyltransferase 1.

artículo científico publicado en 2016

Upregulation of cytidine deaminase in NAT1 knockout breast cancer cells

Urinary acetylated metabolites and N-acetyltransferase-2 genotype in human subjects treated with a para-phenylenediamine-containing oxidative hair dye.

artículo científico publicado en 2004

Using gene-environment interaction analyses to clarify the role of well-done meat and heterocyclic amine exposure in the etiology of colorectal polyps

artículo científico publicado en 2012

Variability in drug metabolizing enzyme activity in HIV-infected patients

artículo científico publicado en 2010

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