Lista de obras - Laura Blair - Dominio Público Uruguay

A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51.

artículo científico publicado en 2011

Accelerated neurodegeneration through chaperone-mediated oligomerization of tau.

artículo científico publicado en 2013

Age-associated epigenetic upregulation of the FKBP5 gene selectively impairs stress resiliency.

artículo científico publicado en 2014

Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy

artículo científico publicado en 2008

Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau.

artículo científico publicado en 2013

Catalysis of proline isomerization and molecular chaperone activity in a tug-of-war

artículo científico publicado en 2020

Chaperone signalling complexes in Alzheimer's disease.

scientific article published on April 2009

Chaperoning of specific tau structure by immunophilin FKBP12 regulates the neuronal resilience to extracellular stress

artículo científico publicado en 2023

DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative-associated proteins.

artículo científico publicado en 2016

Dynamic Aha1 co-chaperone binding to human Hsp90

scientific article published on 06 August 2019

Early Life Stress and High FKBP5 Interact to Increase Anxiety-Like Symptoms through Altered AKT Signaling in the Dorsal Hippocampus

artículo científico publicado en 2019

Epitope analysis following active immunization with tau proteins reveals immunogens implicated in tau pathogenesis

artículo científico publicado en 2014

Exploiting the diversity of the heat-shock protein family for primary and secondary tauopathy therapeutics.

artículo científico publicado en 2011

Facilitating Akt clearance via manipulation of Hsp70 activity and levels.

artículo científico publicado en 2009

Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism

artículo científico publicado en 2012

Hsc70 rapidly engages tau after microtubule destabilization

artículo científico publicado en 2010

Hsp22 with an N-Terminal Domain Truncation Mediates a Reduction in Tau Protein Levels

artículo científico publicado en 2020

Hsp90 Heterocomplexes Regulate Steroid Hormone Receptors: From Stress Response to Psychiatric Disease ⬇️

artículo científico publicado en 2019

Hsp90 activator Aha1 drives production of pathological tau aggregates

artículo científico publicado en 2017

Hsp90 and FKBP51: complex regulators of psychiatric diseases

artículo científico publicado en 2018

Human cyclophilin 40 unravels neurotoxic amyloids

artículo científico publicado en 2017

Imbalance of Hsp70 family variants fosters tau accumulation

artículo científico publicado en 2012

Imbalances in the Hsp90 Chaperone Machinery: Implications for Tauopathies.

artículo científico publicado en 2017

Isoform-selective Hsp90 inhibition rescues model of hereditary open-angle glaucoma

artículo científico publicado en 2017

LPS- induced inflammation exacerbates phospho-tau pathology in rTg4510 mice

artículo científico publicado en 2010

MicroRNA-511 Binds to FKBP5 mRNA, Which Encodes a Chaperone Protein, and Regulates Neuronal Differentiation

artículo científico publicado en 2016

Noncontact Rotational Head Injury Produces Transient Cognitive Deficits but Lasting Neuropathological Changes.

artículo científico publicado en 2016

Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden

artículo científico publicado en 2010

Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice.

artículo científico publicado en 2010

Potential synergy between tau aggregation inhibitors and tau chaperone modulators.

artículo científico publicado en 2013

Repeated repeat problems: Combinatorial effect of C9orf72-derived dipeptide repeat proteins

scientific article published on 09 January 2019

Rhodacyanine derivative selectively targets cancer cells and overcomes tamoxifen resistance

artículo científico publicado en 2012

Small Heat Shock Proteins, Big Impact on Protein Aggregation in Neurodegenerative Disease

scientific article published on 18 September 2019

Spermidine/spermine-N1-acetyltransferase ablation impacts tauopathy-induced polyamine stress response

scientific article published on 29 June 2019

Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex

artículo científico publicado en 2018

Targeting Hsp90 and its co-chaperones to treat Alzheimer's disease

artículo científico publicado en 2014

Targeting the FKBP51/GR/Hsp90 Complex to Identify Functionally Relevant Treatments for Depression and PTSD

artículo científico publicado en 2018

Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation

scientific article published on May 2013

Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy

artículo científico publicado en 2015

The Disease-Associated Chaperone FKBP51 Impairs Cognitive Function by Accelerating AMPA Receptor Recycling

artículo científico publicado en 2019

The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules.

artículo científico publicado en 2010

The diarylheptanoid (+)-aR,11S-myricanol and two flavones from bayberry (Myrica cerifera) destabilize the microtubule-associated protein tau. ⬇️

artículo científico publicado en 2010

The emerging role of peptidyl-prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's disease

artículo científico publicado en 2015

The multiple facets of the Hsp90 machine

artículo científico publicado en 2019

The role of FKBP5 in mood disorders: action of FKBP5 on steroid hormone receptors leads to questions about its evolutionary importance

artículo científico publicado en 2013

Trifunctional High-Throughput Screen Identifies Promising Scaffold To Inhibit Grp94 and Treat Myocilin-Associated Glaucoma.

artículo científico publicado en 2018

Lista de obras de Laura Blair

A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51.

Accelerated neurodegeneration through chaperone-mediated oligomerization of tau.

Age-associated epigenetic upregulation of the FKBP5 gene selectively impairs stress resiliency.

Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy

Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau.

Catalysis of proline isomerization and molecular chaperone activity in a tug-of-war

Chaperone signalling complexes in Alzheimer's disease.

Chaperoning of specific tau structure by immunophilin FKBP12 regulates the neuronal resilience to extracellular stress

DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative-associated proteins.

Dynamic Aha1 co-chaperone binding to human Hsp90

Early Life Stress and High FKBP5 Interact to Increase Anxiety-Like Symptoms through Altered AKT Signaling in the Dorsal Hippocampus

Epitope analysis following active immunization with tau proteins reveals immunogens implicated in tau pathogenesis

Exploiting the diversity of the heat-shock protein family for primary and secondary tauopathy therapeutics.

Facilitating Akt clearance via manipulation of Hsp70 activity and levels.

Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism

Hsc70 rapidly engages tau after microtubule destabilization

Hsp22 with an N-Terminal Domain Truncation Mediates a Reduction in Tau Protein Levels

Hsp90 Heterocomplexes Regulate Steroid Hormone Receptors: From Stress Response to Psychiatric Disease ⬇️

Hsp90 activator Aha1 drives production of pathological tau aggregates

Hsp90 and FKBP51: complex regulators of psychiatric diseases

Human cyclophilin 40 unravels neurotoxic amyloids

Imbalance of Hsp70 family variants fosters tau accumulation

Imbalances in the Hsp90 Chaperone Machinery: Implications for Tauopathies.

Isoform-selective Hsp90 inhibition rescues model of hereditary open-angle glaucoma

LPS- induced inflammation exacerbates phospho-tau pathology in rTg4510 mice

MicroRNA-511 Binds to FKBP5 mRNA, Which Encodes a Chaperone Protein, and Regulates Neuronal Differentiation

Noncontact Rotational Head Injury Produces Transient Cognitive Deficits but Lasting Neuropathological Changes.

Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden

Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice.

Potential synergy between tau aggregation inhibitors and tau chaperone modulators.

Repeated repeat problems: Combinatorial effect of C9orf72-derived dipeptide repeat proteins

Rhodacyanine derivative selectively targets cancer cells and overcomes tamoxifen resistance

Small Heat Shock Proteins, Big Impact on Protein Aggregation in Neurodegenerative Disease

Spermidine/spermine-N1-acetyltransferase ablation impacts tauopathy-induced polyamine stress response

Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex

Targeting Hsp90 and its co-chaperones to treat Alzheimer's disease

Targeting the FKBP51/GR/Hsp90 Complex to Identify Functionally Relevant Treatments for Depression and PTSD

Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation

Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy

The Disease-Associated Chaperone FKBP51 Impairs Cognitive Function by Accelerating AMPA Receptor Recycling

The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules.

The diarylheptanoid (+)-aR,11S-myricanol and two flavones from bayberry (Myrica cerifera) destabilize the microtubule-associated protein tau. ⬇️

The emerging role of peptidyl-prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's disease

The multiple facets of the Hsp90 machine

The role of FKBP5 in mood disorders: action of FKBP5 on steroid hormone receptors leads to questions about its evolutionary importance

Trifunctional High-Throughput Screen Identifies Promising Scaffold To Inhibit Grp94 and Treat Myocilin-Associated Glaucoma.