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Lista de obras de Patrick Bulau

Affinity purification of erythropoietin from cell culture supernatant combined with MALDI-TOF-MS analysis of erythropoietin N-glycosylation.

artículo científico

Analysis of methylarginine metabolism in the cardiovascular system identifies the lung as a major source of ADMA

artículo científico publicado en 2007

Analytical protein a chromatography as a quantitative tool for the screening of methionine oxidation in monoclonal antibodies.

artículo científico publicado en 2012

Application of Hydrogen/Deuterium Exchange-Mass Spectrometry to Biopharmaceutical Development Requirements: Improved Sensitivity to Detection of Conformational Changes

artículo científico publicado en 2017

Applying mini-bore HPAEC-MS/MS for the characterization and quantification of Fc N-glycans from heterogeneously glycosylated IgGs.

artículo científico publicado en 2016

Assessment of chemical modifications of sites in the CDRs of recombinant antibodies: Susceptibility vs. functionality of critical quality attributes

artículo científico publicado en 2014

Assessment of susceptible chemical modification sites of trastuzumab and endogenous human immunoglobulins at physiological conditions

scientific article published on 05 April 2018

Characterization and prediction of positional 4-hydroxyproline and sulfotyrosine, two post-translational modifications that can occur at substantial levels in CHO cells-expressed biotherapeutics

artículo científico publicado en 2019

Characterization of a molt-inhibiting hormone (MIH) of the crayfish, Orconectes limosus, by cDNA cloning and mass spectrometric analysis

artículo científico publicado en 2005

Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles--part 1: separation-based methods

artículo científico publicado en 2015

Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles-Part 2: Mass spectrometric methods

artículo científico publicado en 2015

Detailed Characterization of Monoclonal Antibody Receptor Interaction Using Affinity Liquid Chromatography Hyphenated to Native Mass Spectrometry.

artículo científico publicado en 2017

Detection of a phosphorylated glycine-serine linker in an IgG-based fusion protein.

artículo científico publicado en 2016

Effects of sialic acid linkage on antibody-fragment crystallizable receptor binding and antibody dependent cytotoxicity depend on levels of fucosylation/bisecting

artículo científico publicado en 2019

Extensive Chemical Modifications in the Primary Protein Structure of IgG1 Subvisible Particles Are Necessary for Breaking Immune Tolerance.

artículo científico publicado en 2017

Functional role and species-specific contribution of arginases in pulmonary fibrosis

artículo científico publicado en 2007

High-throughput glycosylation analysis of therapeutic immunoglobulin G by capillary gel electrophoresis using a DNA analyzer

artículo científico publicado en 2014

High-throughput work flow for IgG Fc-glycosylation analysis of biotechnological samples

article published in 2012

Identification and monitoring of host cell proteins by mass spectrometry combined with high performance immunochemistry testing

artículo científico publicado en 2013

Identification of neuropeptides from the sinus gland of the crayfish Orconectes limosus using nanoscale on-line liquid chromatography tandem mass spectrometry.

artículo científico publicado en 2004

Identification of potential sites for tryptophan oxidation in recombinant antibodies using tert-butylhydroperoxide and quantitative LC-MS

artículo científico publicado en 2011

In vitro glycoengineering of IgG1 and its effect on Fc receptor binding and ADCC activity

artículo científico publicado en 2015

Increased protein arginine methylation in chronic hypoxia: role of protein arginine methyltransferases

scientific journal article

Lung dendritic cells elicited by Fms-like tyrosine 3-kinase ligand amplify the lung inflammatory response to lipopolysaccharide

artículo científico publicado en 2007

Multi-Attribute Monitoring of Complex Erythropoetin Beta Glycosylation by GluC Liquid Chromatography-Mass Spectrometry Peptide Mapping

scientific article published on 19 May 2020

Pyroglutamyl peptidase type I from Trypanosoma brucei: a new virulence factor from African trypanosomes that de-blocks regulatory peptides in the plasma of infected hosts

artículo científico publicado en 2006

Quantitative assessment of arginine methylation in free versus protein-incorporated amino acids in vitro and in vivo using protein hydrolysis and high-performance liquid chromatography

scientific article published on 01 March 2006

Selective Oxidation of Methionine and Tryptophan Residues in a Therapeutic IgG1 Molecule

artículo científico publicado en 2015

Simultaneous assessment of Asp isomerization and Asn deamidation in recombinant antibodies by LC-MS following incubation at elevated temperatures

artículo científico publicado en 2012

Subcellular fractionation of TGF-beta1-stimulated lung epithelial cells: a novel proteomic approach for identifying signaling intermediates.

artículo científico publicado en 2009

Tropolysin, a new oligopeptidase from African trypanosomes

artículo científico publicado en 2005

Two genetic variants of the crustacean hyperglycemic hormone (CHH) from the Australian crayfish, Cherax destructor: detection of chiral isoforms due to posttranslational modification.

artículo científico publicado en 2003