Lista de obras - Jan Wijnholds - Dominio Público Uruguay

"Basal Cell Migration" in Regeneration of the Corneal Wound-Bed

artículo científico publicado en 2019

A family of drug transporters: the multidrug resistance-associated proteins.

artículo científico publicado en 2000

A new CRB1 rat mutation links Müller glial cells to retinal telangiectasia.

artículo científico publicado en 2015

A single amino acid substitution (Cys249Trp) in Crb1 causes retinal degeneration and deregulates expression of pituitary tumor transforming gene Pttg1.

artículo científico publicado en 2007

AAV Gene Augmentation Therapy for CRB1-Associated Retinitis Pigmentosa

artículo científico publicado en 2018

AAV Serotype Testing on Cultured Human Donor Retinal Explants

artículo científico publicado en 2018

Binding of a bZip protein to the estrogen-inducible apoVLDL II promoter

scientific article published on 01 September 1994

Bone spicule pigment formation in retinitis pigmentosa: insights from a mouse model.

artículo científico publicado en 2009

CLINICAL AND GENETIC CHARACTERISTICS OF MALE PATIENTS WITH RPGR-ASSOCIATED RETINAL DYSTROPHIES: A Long-Term Follow-up Study

artículo científico publicado en 2018

CRB2 Loss in Rod Photoreceptors Is Associated with Progressive Loss of Retinal Contrast Sensitivity ⬇️

artículo científico

CRB2 acts as a modifying factor of CRB1-related retinal dystrophies in mice

artículo científico publicado en 2014

CRB2 in immature photoreceptors determines the superior-inferior symmetry of the developing retina to maintain retinal structure and function

artículo científico publicado en 2018

Characterization of Pax-6 and Hoxa-1 binding to the promoter region of the neural cell adhesion molecule L1

scientific article published on 01 September 1994

Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells

artículo científico publicado en 2003

Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5

artículo científico publicado en 2003

Cloning and characterisation of a nuclear, site specific ssDNA binding protein.

artículo científico publicado en 1995

Contribution of the drug transporter ABCG2 (breast cancer resistance protein) to resistance against anticancer nucleosides.

artículo científico publicado en 2008

Crb1 is a determinant of retinal apical Müller glia cell features

artículo científico publicado en 2007

Crumbs 2 prevents cortical abnormalities in mouse dorsal telencephalon.

artículo científico publicado en 2016

Crumbs homologue 1 in polarity and blindness.

artículo científico publicado en 2004

Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure

scientific journal article

Crumbs2 mediates ventricular layer remodelling to form the spinal cord central canal

artículo científico publicado en 2020

Crumbs2 promotes cell ingression during the epithelial-to-mesenchymal transition at gastrulation

scientific journal article

Defining Phenotype, Tropism, and Retinal Gene Therapy Using Adeno-Associated Viral Vectors (AAVs) in New-Born Brown Norway Rats with a Spontaneous Mutation in Crb1

artículo científico publicado en 2021

Differential susceptibility of multidrug resistance protein-1 deficient mice to DSS and TNBS-induced colitis.

artículo científico publicado en 2002

Estrogen-inducible and liver-specific expression of the chicken Very Low Density Apolipoprotein II gene locus in transgenic mice.

artículo científico publicado en 1993

GFAP-driven GFP expression in activated mouse Müller glial cells aligning retinal blood vessels following intravitreal injection of AAV2/6 vectors

artículo científico publicado en 2010

Gene therapy into photoreceptors and Müller glial cells restores retinal structure and function in CRB1 retinitis pigmentosa mouse models

artículo científico publicado en 2015

Genetic and Molecular Approaches to Study Neuronal Migration in the Developing Cerebral Cortex

artículo científico publicado en 2017

Genotypic and Phenotypic Characteristics of CRB1-Associated Retinal Dystrophies: A Long-Term Follow-up Study

artículo científico publicado en 2017

Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5

artículo científico publicado en 2019

In vivo confocal imaging of the retina in animal models using scanning laser ophthalmoscopy

artículo científico publicado en 2005

Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein

scientific article published on 01 November 1997

Isolation of Crb1, a mouse homologue of Drosophila crumbs, and analysis of its expression pattern in eye and brain

artículo científico publicado en 2002

Loss of CRB2 in Müller glial cells modifies a CRB1-associated retinitis pigmentosa phenotype into a Leber congenital amaurosis phenotype

scientific article published on 01 January 2019

Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene ⬇️

artículo científico publicado el 21 de septiembre de 2012

MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex.

artículo científico publicado en 2013

MPP3 regulates levels of PALS1 and adhesion between photoreceptors and Müller cells.

artículo científico publicado en 2013

MPP5 recruits MPP4 to the CRB1 complex in photoreceptors

artículo científico publicado en 2005

MRP6 (ABCC6) detection in normal human tissues and tumors.

artículo científico publicado en 2002

Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides.

artículo científico publicado en 2005

Mice lacking the multidrug resistance protein 1 are resistant to Streptococcus pneumoniae-induced pneumonia

artículo científico publicado en 2001

Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background

artículo científico publicado en 2013

Multidrug Resistance Protein 1 Protects the Oropharyngeal Mucosal Layer and the Testicular Tubules against Drug-induced Damage ⬇️

artículo científico publicado el 7 de septiembre de 1998

Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs

artículo científico publicado en 2000

Noninvasive, in vivo assessment of mouse retinal structure using optical coherence tomography

artículo científico publicado en 2009

PALS1 is essential for retinal pigment epithelium structure and neural retina stratification.

artículo científico publicado en 2011

Pals1/Mpp5 is required for correct localization of Crb1 at the subapical region in polarized Muller glia cells

scientific journal article

Pax-3-DNA interaction: flexibility in the DNA binding and induction of DNA conformational changes by paired domains.

artículo científico

Pax: gene regulators in the developing nervous system.

artículo científico publicado en 1993

Production of iPS-Derived Human Retinal Organoids for Use in Transgene Expression Assays.

artículo científico publicado en 2018

Protein O-Glucosyltransferase 1 (POGLUT1) Promotes Mouse Gastrulation through Modification of the Apical Polarity Protein CRUMBS2

artículo científico publicado en 2015

Pseudoxanthoma elasticum: a clinical, histopathological, and molecular update.

artículo científico publicado en 2003

RPGR-Associated Dystrophies: Clinical, Genetic, and Histopathological Features

scientific article published on 28 January 2020

Retinogenesis of the Human Fetal Retina: An Apical Polarity Perspective

artículo científico publicado en 2019

Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies.

artículo científico publicado en 2000

Specific tools for targeting and expression in Müller glial cells

artículo científico publicado en 2014

TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals

artículo científico publicado en 2009

Targeted ablation of CRB1 and CRB2 in retinal progenitor cells mimics Leber congenital amaurosis

artículo científico publicado en 2013

Targeted ablation of Crb2 in photoreceptor cells induces retinitis pigmentosa.

artículo científico publicado en 2014

The CRB1 Complex: Following the Trail of Crumbs to a Feasible Gene Therapy Strategy.

artículo científico publicado en 2017

The CRB1 and adherens junction complex proteins in retinal development and maintenance.

artículo científico

The Spectrum of Structural and Functional Abnormalities in Female Carriers of Pathogenic Variants in the RPGR Gene

article

The apical complex couples cell fate and cell survival to cerebral cortical development

artículo científico publicado en 2010

The human multidrug resistance protein MRP5 transports folates and can mediate cellular resistance against antifolates.

artículo científico publicado en 2005

The multidrug resistance protein 1 (Mrp1), but not Mrp5, mediates export of glutathione and glutathione disulfide from brain astrocytes.

artículo científico publicado en 2006

The potential impact of drug transporters on nucleoside-analog-based antiviral chemotherapy.

artículo científico publicado en 2004

Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells.

artículo científico publicado en 2002

Towards understanding CRUMBS function in retinal dystrophies.

artículo científico publicado en 2006

Transport of glutathione prostaglandin A conjugates by the multidrug resistance protein 1.

artículo científico publicado en 1997

c/CEPB, a chicken transcription factor of the leucine-zipper C/EBP family [corrected]

artículo científico publicado en 1992

cGMP transport by vesicles from human and mouse erythrocytes

scientific article published on 01 January 2007

Lista de obras de Jan Wijnholds

"Basal Cell Migration" in Regeneration of the Corneal Wound-Bed

A family of drug transporters: the multidrug resistance-associated proteins.

A new CRB1 rat mutation links Müller glial cells to retinal telangiectasia.

A single amino acid substitution (Cys249Trp) in Crb1 causes retinal degeneration and deregulates expression of pituitary tumor transforming gene Pttg1.

AAV Gene Augmentation Therapy for CRB1-Associated Retinitis Pigmentosa

AAV Serotype Testing on Cultured Human Donor Retinal Explants

Binding of a bZip protein to the estrogen-inducible apoVLDL II promoter

Bone spicule pigment formation in retinitis pigmentosa: insights from a mouse model.

CLINICAL AND GENETIC CHARACTERISTICS OF MALE PATIENTS WITH RPGR-ASSOCIATED RETINAL DYSTROPHIES: A Long-Term Follow-up Study

CRB2 Loss in Rod Photoreceptors Is Associated with Progressive Loss of Retinal Contrast Sensitivity ⬇️

CRB2 acts as a modifying factor of CRB1-related retinal dystrophies in mice

CRB2 in immature photoreceptors determines the superior-inferior symmetry of the developing retina to maintain retinal structure and function

Characterization of Pax-6 and Hoxa-1 binding to the promoter region of the neural cell adhesion molecule L1

Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells

Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5

Cloning and characterisation of a nuclear, site specific ssDNA binding protein.

Contribution of the drug transporter ABCG2 (breast cancer resistance protein) to resistance against anticancer nucleosides.

Crb1 is a determinant of retinal apical Müller glia cell features

Crumbs 2 prevents cortical abnormalities in mouse dorsal telencephalon.

Crumbs homologue 1 in polarity and blindness.

Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure

Crumbs2 mediates ventricular layer remodelling to form the spinal cord central canal

Crumbs2 promotes cell ingression during the epithelial-to-mesenchymal transition at gastrulation

Defining Phenotype, Tropism, and Retinal Gene Therapy Using Adeno-Associated Viral Vectors (AAVs) in New-Born Brown Norway Rats with a Spontaneous Mutation in Crb1

Differential susceptibility of multidrug resistance protein-1 deficient mice to DSS and TNBS-induced colitis.

Estrogen-inducible and liver-specific expression of the chicken Very Low Density Apolipoprotein II gene locus in transgenic mice.

GFAP-driven GFP expression in activated mouse Müller glial cells aligning retinal blood vessels following intravitreal injection of AAV2/6 vectors

Gene therapy into photoreceptors and Müller glial cells restores retinal structure and function in CRB1 retinitis pigmentosa mouse models

Genetic and Molecular Approaches to Study Neuronal Migration in the Developing Cerebral Cortex

Genotypic and Phenotypic Characteristics of CRB1-Associated Retinal Dystrophies: A Long-Term Follow-up Study

Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5

In vivo confocal imaging of the retina in animal models using scanning laser ophthalmoscopy

Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein

Isolation of Crb1, a mouse homologue of Drosophila crumbs, and analysis of its expression pattern in eye and brain

Loss of CRB2 in Müller glial cells modifies a CRB1-associated retinitis pigmentosa phenotype into a Leber congenital amaurosis phenotype

Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene ⬇️

MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex.

MPP3 regulates levels of PALS1 and adhesion between photoreceptors and Müller cells.

MPP5 recruits MPP4 to the CRB1 complex in photoreceptors

MRP6 (ABCC6) detection in normal human tissues and tumors.

Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides.

Mice lacking the multidrug resistance protein 1 are resistant to Streptococcus pneumoniae-induced pneumonia

Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background

Multidrug Resistance Protein 1 Protects the Oropharyngeal Mucosal Layer and the Testicular Tubules against Drug-induced Damage ⬇️

Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs

Noninvasive, in vivo assessment of mouse retinal structure using optical coherence tomography

PALS1 is essential for retinal pigment epithelium structure and neural retina stratification.

Pals1/Mpp5 is required for correct localization of Crb1 at the subapical region in polarized Muller glia cells

Pax-3-DNA interaction: flexibility in the DNA binding and induction of DNA conformational changes by paired domains.

Pax: gene regulators in the developing nervous system.

Production of iPS-Derived Human Retinal Organoids for Use in Transgene Expression Assays.

Protein O-Glucosyltransferase 1 (POGLUT1) Promotes Mouse Gastrulation through Modification of the Apical Polarity Protein CRUMBS2

Pseudoxanthoma elasticum: a clinical, histopathological, and molecular update.

RPGR-Associated Dystrophies: Clinical, Genetic, and Histopathological Features

Retinogenesis of the Human Fetal Retina: An Apical Polarity Perspective

Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies.

Specific tools for targeting and expression in Müller glial cells

TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals

Targeted ablation of CRB1 and CRB2 in retinal progenitor cells mimics Leber congenital amaurosis

Targeted ablation of Crb2 in photoreceptor cells induces retinitis pigmentosa.

The CRB1 Complex: Following the Trail of Crumbs to a Feasible Gene Therapy Strategy.

The CRB1 and adherens junction complex proteins in retinal development and maintenance.

The Spectrum of Structural and Functional Abnormalities in Female Carriers of Pathogenic Variants in the RPGR Gene

The apical complex couples cell fate and cell survival to cerebral cortical development

The human multidrug resistance protein MRP5 transports folates and can mediate cellular resistance against antifolates.

The multidrug resistance protein 1 (Mrp1), but not Mrp5, mediates export of glutathione and glutathione disulfide from brain astrocytes.

The potential impact of drug transporters on nucleoside-analog-based antiviral chemotherapy.

Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells.

Towards understanding CRUMBS function in retinal dystrophies.

Transport of glutathione prostaglandin A conjugates by the multidrug resistance protein 1.

c/CEPB, a chicken transcription factor of the leucine-zipper C/EBP family [corrected]

cGMP transport by vesicles from human and mouse erythrocytes