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Lista de obras de Enric I. Canela

A Sensitive Enzymatic Method of Sulfite Determination

A Significant Role of the Truncated Ghrelin Receptor GHS-R1b in Ghrelin-induced Signaling in Neurons.

artículo científico publicado en 2016

A computer program for enzyme kinetics that combines model discrimination, parameter refinement and sequential experimental design.

artículo científico publicado en 1986

A free derivative program for non-linear regression analysis of enzyme kinetics to be used on small computers.

artículo científico publicado en 1984

A hybrid indoloquinolizidine peptide as allosteric modulator of dopamine D1 receptors

artículo científico publicado en 2009

A model for adenosine transport and metabolism

artículo científico publicado en 1992

A model of the pentose phosphate pathway in rat liver cells.

artículo científico publicado en 1995

A new strategy for the evaluation of force parameters from quantum mechanical computations

A program for deriving rate equations using small computers.

artículo científico publicado en 1983

A program for the numerical integration of enzyme kinetic equations using small computers.

artículo científico publicado en 1984

A quantum chemical study of the enzymatic deamination of benzoadenine derivatives. A theoretical model of the interactions occurring between nucleosides and the active site of adenosine deaminase.

artículo científico publicado en 1990

A1 Adenosine Receptors Accumulate in Neurodegenerative Structures in Alzheimer's Disease and Mediate Both Amyloid Precursor Protein Processing and Tau Phosphorylation and Translocation

scholarly article by Ester Angulo et al published 5 April 2006 in Brain Pathology

A2A adenosine receptor ligand binding and signalling is allosterically modulated by adenosine deaminase

artículo científico publicado en 2011

Ab initio study of the protonation and the tautomerism of the 7-aminopyrazolopyrimidine molecule

Accuracy and precision in the determination of stokes radii and molecular masses of proteins by gel filtration chromatography

artículo científico publicado en 1989

Actin-binding protein alpha-actinin-1 interacts with the metabotropic glutamate receptor type 5b and modulates the cell surface expression and function of the receptor

artículo científico publicado en 2007

Adenine nucleotides and adenosine metabolism in pig kidney proximal tubule membranes

artículo científico publicado en 1993

Adenosine (Ado) uptake in brush-border membrane vesicles from rat kidney (BBM)

artículo científico publicado en 1991

Adenosine A(2A) Receptors and A(2A) Receptor Heteromers as Key Players in Striatal Function

artículo científico publicado en 2011

Adenosine Deaminase Interacts with A1 Adenosine Receptors in Pig Brain Cortical Membranes

Adenosine deaminase affects ligand-induced signalling by interacting with cell surface adenosine receptors

artículo científico publicado en 1996

Adenosine metabolism in kidney slices under normoxic conditions.

artículo científico publicado en 1990

Adenosine-cannabinoid receptor interactions. Implications for striatal function

artículo científico publicado en 2010

Adenosine-glutamate receptor-receptor interactions in the central nervous system

Adenosine/dopamine receptor-receptor interactions in the central nervous system

scholarly article by Rafael Franco et al published January 2001 in Drug Development Research

Allosteric interactions between agonists and antagonists within the adenosine A2A receptor-dopamine D2 receptor heterotetramer

artículo científico publicado en 2015

Ammonium toxicity in different cell lines

article

An Improved Purification Procedure for Sulfite Oxidase from Bovine Liver

artículo científico publicado en 1991

Analysis of ultradian heat production and aortic core temperature rhythms in the rat

scientific article published on 01 March 1993

Application of inverse regression for estimating molecular masses and Stokes radii of globular proteins by gel filtration chromatography.

artículo científico publicado en 1990

Basic concepts in G-protein-coupled receptor homo- and heterodimerization.

artículo científico publicado en 2007

Binding and Signaling Studies Disclose a Potential Allosteric Site for Cannabidiol in Cannabinoid CB2 Receptors.

artículo científico publicado en 2017

Biochemical systems theory: increasing predictive power by using second-order derivatives measurements.

artículo científico publicado en 1991

Cannabinoid receptors CB1 and CB2 form functional heteromers in brain

artículo científico publicado en 2012

Cell surface adenosine deaminase: much more than an ectoenzyme.

artículo científico publicado en 1997

Characterization of bovine liver guanine aminohydrolase

scientific article published on 01 January 1981

Characterization of the forms of bovine liver adenosine deaminase

artículo científico publicado en 1982

Circadian-related heteromerization of adrenergic and dopamine D₄ receptors modulates melatonin synthesis and release in the pineal gland

artículo científico publicado en 2012

Coaggregation, cointernalization, and codesensitization of adenosine A2A receptors and dopamine D2 receptors

artículo científico publicado en 2002

Cocaine Effects on Dopaminergic Transmission Depend on a Balance between Sigma-1 and Sigma-2 Receptor Expression

artículo científico publicado en 2018

Cocaine disrupts histamine H3 receptor modulation of dopamine D1 receptor signaling: σ1-D1-H3 receptor complexes as key targets for reducing cocaine's effects.

artículo científico publicado en 2014

Cocaine inhibits dopamine D2 receptor signaling via sigma-1-D2 receptor heteromers

artículo científico publicado en 2013

Cocaine produces D2R-mediated conformational changes in the adenosine A(2A)R-dopamine D2R heteromer

artículo científico publicado en 2010

Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors

artículo científico publicado en 2015

Comparative study of chicken liver xanthine dehydrogenase and bovine liver xanthine oxidase. dehydrogenase activity of xanthine oxidase (author's transl)

artículo científico publicado el 1 de marzo de 1979

Computer simulation of purine metabolism

artículo científico publicado el 15 de octubre de 1984

Control analysis of transition times. Extension of analysis and matrix method.

artículo científico publicado en 1991

Cross-communication between Gi and Gs in a G-protein-coupled receptor heterotetramer guided by a receptor C-terminal domain.

artículo científico publicado en 2018

Detection of heteromerization of more than two proteins by sequential BRET-FRET.

artículo científico publicado en 2008

Detection of heteromers formed by cannabinoid CB1, dopamine D2, and adenosine A2A G-protein-coupled receptors by combining bimolecular fluorescence complementation and bioluminescence energy transfer.

artículo científico publicado en 2008

Detection of receptor heteromers involving dopamine receptors by the sequential BRET-FRET technology

artículo científico publicado en 2013

Determination of the conformational preferences of adenosine at the active site of adenosine deaminase

artículo científico publicado en 1990

Differential effect of amphetamine over the corticotropin-releasing factor CRF2 receptor, the orexin OX1 receptor and the CRF2-OX1 heteroreceptor complex

artículo científico publicado en 2018

Dimer-based model for heptaspanning membrane receptors

scientific article published on 01 July 2005

Direct involvement of sigma-1 receptors in the dopamine D1 receptor-mediated effects of cocaine

artículo científico publicado en 2010

Dopamine D1-histamine H3 receptor heteromers provide a selective link to MAPK signaling in GABAergic neurons of the direct striatal pathway

artículo científico publicado en 2010

Dopamine-galanin receptor heteromers modulate cholinergic neurotransmission in the rat ventral hippocampus.

artículo científico publicado en 2011

Enzyme kinetic studies from progress curves.

artículo científico publicado en 1986

Enzyme-enzyme interactions and metabolite channelling: alternative mechanisms and their evolutionary significance.

artículo científico publicado en 1994

Epidermal growth factor (EGF)-induced up-regulation and agonist- and antagonist-induced desensitization and internalization of A1 adenosine receptors in a pituitary-derived cell line.

artículo científico publicado en 1999

Evidence for functional pre-coupled complexes of receptor heteromers and adenylyl cyclase.

artículo científico publicado en 2018

Experimental strategy to study the pH dependence of the kinetic behavior of enzymes: practical application to chicken liver xanthine dehydrogenase.

artículo científico publicado en 1993

Functional selectivity of allosteric interactions within G protein-coupled receptor oligomers: the dopamine D1-D3 receptor heterotetramer.

artículo científico publicado en 2014

Functional μ-Opioid-Galanin Receptor Heteromers in the Ventral Tegmental Area.

artículo científico publicado en 2016

G protein-coupled receptor heteromers as new targets for drug development

artículo científico publicado en 2010

GPCR homomers and heteromers: a better choice as targets for drug development than GPCR monomers?

artículo científico publicado en 2009

Gi protein coupling to adenosine A1-A2A receptor heteromers in human brain caudate nucleus.

artículo científico publicado en 2010

Glycogen Structure: an Evolutionary View

Heptaspanning membrane receptors and cytoskeletal/scaffolding proteins: focus on adenosine, dopamine, and metabotropic glutamate receptor function

artículo científico publicado en 2005

Heterogeneous localization of some purine enzymes in subcellular fractions of rat brain and cerebellum.

artículo científico publicado en 1986

Heteroreceptor Complexes Formed by Dopamine D1, Histamine H3, and N-Methyl-D-Aspartate Glutamate Receptors as Targets to Prevent Neuronal Death in Alzheimer's Disease

artículo científico publicado en 2016

Homodimerization of adenosine A2A receptors: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer

artículo científico publicado en 2004

Homodimerization of adenosine A₁ receptors in brain cortex explains the biphasic effects of caffeine

artículo científico publicado en 2013

Human adenosine deaminase as an allosteric modulator of human A(1) adenosine receptor: abolishment of negative cooperativity for [H](R)-pia binding to the caudate nucleus

artículo científico publicado en 2008

Identification and rejection of outliers in enzyme kinetics.

artículo científico publicado en 1988

Immunological identification of A1adenosine receptors in brain cortex

scientific article published on 01 December 1995

Indoloquinolizidine-peptide hybrids as multiple agonists for D1 and D2 dopamine receptors.

artículo científico publicado en 2009

Interactions between calmodulin, adenosine A2A, and dopamine D2 receptors

artículo científico publicado en 2009

Interactions between histamine H3 and dopamine D2 receptors and the implications for striatal function

artículo científico publicado en 2008

Interactions between intracellular domains as key determinants of the quaternary structure and function of receptor heteromers

artículo científico publicado en 2010

Interdependence between cooperativity and control coefficients.

artículo científico publicado en 1989

Intracellular calcium levels determine differential modulation of allosteric interactions within G protein-coupled receptor heteromers.

artículo científico publicado en 2014

Kinetic mechanism of chicken liver xanthine dehydrogenase.

artículo científico publicado en 1988

L-DOPA disrupts adenosine A(2A)-cannabinoid CB(1)-dopamine D(2) receptor heteromer cross-talk in the striatum of hemiparkinsonian rats: biochemical and behavioral studies

artículo científico publicado en 2014

L-DOPA-treatment in primates disrupts the expression of A(2A) adenosine-CB(1) cannabinoid-D(2) dopamine receptor heteromers in the caudate nucleus

artículo científico publicado en 2013

Ligand-Induced Phosphorylation, Clustering, and Desensitization of A1Adenosine Receptors

scientific article published on 01 November 1997

Ligand-induced caveolae-mediated internalization of A1 adenosine receptors: morphological evidence of endosomal sorting and receptor recycling

artículo científico publicado en 2003

Marked changes in signal transduction upon heteromerization of dopamine D1 and histamine H3 receptors

artículo científico publicado en 2009

Metabolic pathway characterization from transient response data obtained in situ: parameter estimation in S-system models.

artículo científico publicado en 1993

Metabotropic glutamate 1alpha and adenosine A1 receptors assemble into functionally interacting complexes.

artículo científico publicado en 2001

Metabotropic glutamate type 1alpha receptor localizes in low-density caveolin-rich plasma membrane fractions

artículo científico publicado en 2003

Modulation of GH4 Cell Cycle via A1 Adenosine Receptors

article published in 2002

Modulation of adenosine agonist [3H]N6-(R)-phenylisopropyladenosine binding to pig brain cortical membranes by changes of membrane fluidity and of medium physicochemical characteristics.

artículo científico publicado en 1992

Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease

artículo científico publicado en 2020

Molecular Evidence of Adenosine Deaminase Linking Adenosine A2A Receptor and CD26 Proteins.

artículo científico publicado en 2018

Molecular mechanisms involved in the adenosine A and A receptor-induced neuronal differentiation in neuroblastoma cells and striatal primary cultures

artículo científico publicado en 2005

Moonlighting adenosine deaminase: a target protein for drug development

artículo científico publicado en 2014

Mutual regulation between metabotropic glutamate type 1alpha receptor and caveolin proteins: from traffick to constitutive activity

artículo científico publicado en 2004

Novel pharmacological targets based on receptor heteromers

artículo científico publicado en 2008

Old and new ways to calculate the affinity of agonists and antagonists interacting with G-protein-coupled monomeric and dimeric receptors: the receptor-dimer cooperativity index.

artículo científico publicado en 2007

On the Nested Hierarchical Organization of CNS: Basic Characteristics of Neuronal Molecular Networks

On the molecular basis of the receptor mosaic hypothesis of the engram

artículo científico publicado en 2004

Optimal association-saturation procedure for estimating association and dissociation rate parameters in receptor studies. Application to solubilized A1 adenosine receptors.

artículo científico publicado en 1992

Orexin A/Hypocretin Modulates Leptin Receptor-Mediated Signaling by Allosteric Modulations Mediated by the Ghrelin GHS-R1A Receptor in Hypothalamic Neurons.

artículo científico publicado en 2017

Orexin-corticotropin-releasing factor receptor heteromers in the ventral tegmental area as targets for cocaine

artículo científico publicado en 2015

Partners for adenosine A1 receptors

artículo científico publicado en 2005

Performance Indices in Metabolic Systems: a Criterion for Evaluating Effectiveness in Metabolic Regulation

Platforms for the identification of GPCR targets, and of orthosteric and allosteric modulators.

artículo científico

Practical Determination of Control Coefficients in Metabolic Pathways

article published in 1990

Preparative purification of adenosine deaminase from human erythrocytes by affinity chromatography

Presynaptic control of striatal glutamatergic neurotransmission by adenosine A1-A2A receptor heteromers

artículo científico publicado en 2006

Production of functional recombinant G-protein coupled receptors for heteromerization studies

artículo científico publicado en 2011

Purification and properties of bovine liver aldehyde oxidase

scientific article published in 1987

Purification of Adenosine Deaminase from Chicken-Egg Yolk by Affinity Column Chromatography

artículo científico publicado en 1990

Purification properties and functional groups of bovine liver xanthine oxidase

scientific article published in 1987

Quantum Chemical Study of the Electronic and Conformational Characteristics of Adenosine and 8-Substituted Derivatives: Functional Implications in the Mechanism of Reaction of Adenosine Deaminase

artículo científico publicado en 1990

Quaternary structure of a G-protein-coupled receptor heterotetramer in complex with Gi and Gs.

artículo científico publicado en 2016

Receptor-heteromer mediated regulation of endocannabinoid signaling in activated microglia. Role of CB1 and CB2 receptors and relevance for Alzheimer's disease and levodopa-induced dyskinesia

artículo científico publicado en 2017

Receptor-receptor interactions involving adenosine A1 or dopamine D1 receptors and accessory proteins.

artículo científico publicado en 2006

Regulation of L-Type Calcium Channels in GH4 Cells via A1 Adenosine Receptors

Regulation of epithelial and lymphocyte cell adhesion by adenosine deaminase-CD26 interaction

artículo científico publicado en 2002

Regulation of heptaspanning-membrane-receptor function by dimerization and clustering

artículo científico publicado en 2003

Regulation of nitrobenzylthioninosine-sensitive adenosine uptake by cultured kidney cells.

artículo científico publicado en 1994

Reinterpreting anomalous competitive binding experiments within G protein-coupled receptor homodimers using a dimer receptor model

artículo científico publicado en 2019

Role of cannabinoid receptor CB2 in HER2 pro-oncogenic signaling in breast cancer

artículo científico publicado en 2015

Role of histidine residues in agonist and antagonist binding sites of A1 adenosine receptor.

artículo científico publicado en 1993

Simulation of the purine nucleotide cycle as an anaplerotic process in skeletal muscle.

artículo científico publicado en 1987

Singular Location and Signaling Profile of Adenosine A2A-Cannabinoid CB1 Receptor Heteromers in the Dorsal Striatum.

artículo científico publicado en 2017

Solubilization of A1adenosine receptor from pig brain: Characterization and evidence of the role of the cell membrane on the coexistence of high- and low-affinity states

artículo científico publicado en 1990

Striatal adenosine A2A and cannabinoid CB1 receptors form functional heteromeric complexes that mediate the motor effects of cannabinoids

scientific journal article

Striatal pre- and postsynaptic profile of adenosine A(2A) receptor antagonists

artículo científico publicado en 2011

Stronger Dopamine D1 Receptor-Mediated Neurotransmission in Dyskinesia

artículo científico publicado en 2014

Targeting CB2-GPR55 receptor heteromers modulates cancer cell signaling.

artículo científico publicado en 2014

Targeting the dopamine D3 receptor: an overview of drug design strategies

artículo científico publicado en 2016

The Endocannabinoid System as a Target in Cancer Diseases: Are We There Yet?

artículo científico publicado en 2019

The adenosine A2A receptor interacts with the actin-binding protein alpha-actinin

scientific journal article

The association of metabotropic glutamate receptor type 5 with the neuronal Ca2+-binding protein 2 modulates receptor function

artículo científico publicado en 2009

The binding of [3H]R-PIA to A1 adenosine receptors produces a conversion of the high- to the low-affinity state.

artículo científico publicado en 1991

The catalytic site structural gate of adenosine deaminase allosterically modulates ligand binding to adenosine receptors

artículo científico publicado en 2012

The effects of pH on chicken liver xanthine dehydrogenase

artículo científico publicado en 1987

The influence of ammonium ions on the aggregation of chicken liver xanthine dehydrogenase

artículo científico publicado en 1987

The molybdoenzymes xanthine oxidase and aldehyde oxidase contain fast- and slow-DTNB reacting sulphydryl groups

artículo científico publicado en 1992

The neuronal Ca(2+) -binding protein 2 (NECAB2) interacts with the adenosine A(2A) receptor and modulates the cell surface expression and function of the receptor

artículo científico publicado en 2007

The two-state dimer receptor model: a general model for receptor dimers

artículo científico publicado en 2006

Theoretical Approximation to the Reaction Mechanism of Adenosine Deaminase

Theoretical study of the acidic strength of amino acid side chains

Theoretical study of the hydroxyl nucleophilic attack on the 6-aminopyrimidine molecule: functional implications in the reaction mechanism of nucleoside deaminative enzymes

Theoretical study of the protonation and tautomerization of adenosine, formycin, and their 2-NH2 and 2-F derivatives: functional implications in the mechanism of reaction of adenosine deaminase.

artículo científico publicado en 1989

Thermodynamic analysis of agonist and antagonist binding to membrane-bound and solubilized A1 adenosine receptors

artículo científico publicado en 1993

Transcriptional profiling of striatal neurons in response to single or concurrent activation of dopamine D2, adenosine A(2A) and metabotropic glutamate type 5 receptors: focus on beta-synuclein expression

artículo científico publicado en 2012

Useful pharmacological parameters for G-protein-coupled receptor homodimers obtained from competition experiments. Agonist-antagonist binding modulation.

artículo científico publicado en 2009

[Purine catabolism in rat brain (author's transl)]

artículo científico publicado en 1981