Lista de obras - Ralf Herwig - Dominio Público Uruguay

"4D Biology for health and disease" workshop report

artículo científico

A Systems Biology Approach for Identifying Hepatotoxicant Groups Based on Similarity in Mechanisms of Action and Chemical Structure

artículo científico publicado en 2016

A gene expression map of human chromosome 21 orthologues in the mouse

artículo científico publicado en 2002

A global view of gene expression in lithium and zinc treated sea urchin embryos: new components of gene regulatory networks

artículo científico publicado en 2007

A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity

artículo científico publicado en 2017

A second generation radiation hybrid map to aid the assembly of the bovine genome sequence

artículo científico publicado en 2006

ARH-seq: identification of differential splicing in RNA-seq data

artículo científico publicado en 2014

ARH: predicting splice variants from genome-wide data with modified entropy

artículo científico publicado en 2009

Activation of AMP-activated protein kinase sensitizes lung cancer cells and H1299 xenografts to erlotinib

artículo científico publicado en 2014

Age-specific hormonal decline is accompanied by transcriptional changes in human sebocytes in vitro

artículo científico

Aging of human sebocytes in vitro induced by exposure to a defined hormone environment

artículo científico publicado en 2006

An integrative computational analysis provides evidence for FBN1-associated network deregulation in trisomy 21

scientific article published on 20 June 2013

An oligonucleotide fingerprint normalized and expressed sequence tag characterized zebrafish cDNA library

artículo científico publicado en 2001

Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells

artículo científico publicado en 2006

Analyzing and interpreting genome data at the network level with ConsensusPathDB

artículo científico publicado en 2016

Cluster-based assessment of protein-protein interaction confidence

artículo científico publicado en 2012

Comparative gene expression profiling by oligonucleotide fingerprinting ⬇️

artículo científico publicado el 1 de mayo de 1998

Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage

artículo científico publicado en 2010

Consensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cells

artículo científico publicado en 2011

ConsensusPathDB--a database for integrating human functional interaction networks

artículo científico

ConsensusPathDB: toward a more complete picture of cell biology

artículo científico publicado en 2011

Conserved molecular portraits of bovine and human blastocysts as a consequence of the transition from maternal to embryonic control of gene expression

artículo científico publicado en 2007

Construction of a 'unigene' cDNA clone set by oligonucleotide fingerprinting allows access to 25 000 potential sugar beet genes

artículo científico publicado en 2002

Construction of a pig physical interactome using sequence homology and a comprehensive reference human interactome

artículo científico publicado en 2012

Cross-species hybridisation of human and bovine orthologous genes on high density cDNA microarrays

artículo científico publicado en 2004

DEFOG: a practical scheme for deciphering families of genes

artículo científico publicado en 2002

DIPSBC--data integration platform for systems biology collaborations

artículo científico publicado en 2012

DNA-methylome analysis of mouse intestinal adenoma identifies a tumour-specific signature that is partly conserved in human colon cancer

artículo científico publicado en 2013

Diet-induced gene expression of isolated pancreatic islets from a polygenic mouse model of the metabolic syndrome.

artículo científico publicado en 2009

Dynamics of biological systems: role of systems biology in medical research

artículo científico publicado en 2006

Establishment of T cell-specific and natural killer cell-specific unigene sets: towards high-throughput genomics of leukaemia.

artículo científico publicado en 2004

Evaluation of database-derived pathway development for enabling biomarker discovery for hepatotoxicity

artículo científico publicado en 2014

Evidence mining and novelty assessment of protein-protein interactions with the ConsensusPathDB plugin for Cytoscape

artículo científico publicado en 2010

Exploring potential target genes of signaling pathways by predicting conserved transcription factor binding sites

artículo científico publicado en 2003

Expression profiling and comparative genomics identify a conserved regulatory region controlling midline expression in the zebrafish embryo

artículo científico publicado en 2004

GeNGe: systematic generation of gene regulatory networks

artículo científico publicado en 2009

Gene expression variation in Down's syndrome mice allows prioritization of candidate genes

artículo científico publicado en 2007

Generation, annotation, evolutionary analysis, and database integration of 20,000 unique sea urchin EST clusters

artículo científico publicado en 2003

Human embryonic stem cell derived hepatocyte-like cells as a tool for in vitro hazard assessment of chemical carcinogenicity

artículo científico publicado en 2011

Identification of QTL affecting resistance/susceptibility to acute Actinobacillus pleuropneumoniae infection in swine

artículo científico publicado en 2014

Identification of marker genes for type 2 diabetes

artículo científico publicado en 2007

Identification of nodal signaling targets by array analysis of induced complex probes

artículo científico publicado en 2001

In silico identification of a core regulatory network of OCT4 in human embryonic stem cells using an integrated approach

artículo científico publicado en 2009

IntScore: a web tool for confidence scoring of biological interactions

artículo científico publicado en 2012

Integrated pathway-level analysis of transcriptomics and metabolomics data with IMPaLA.

artículo científico publicado en 2011

Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective

artículo científico publicado en 2015

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells

artículo científico publicado en 2013

Large-scale clustering of cDNA-fingerprinting data

artículo científico publicado en 1999

MEDIPS: genome-wide differential coverage analysis of sequencing data derived from DNA enrichment experiments

artículo científico publicado en 2013

Matrix metalloproteinases of epithelial origin in facial sebum of patients with acne and their regulation by isotretinoin

artículo científico publicado en 2005

Meta-analysis approach identifies candidate genes and associated molecular networks for type-2 diabetes mellitus

artículo científico publicado en 2008

Meta-analysis of heterogeneous Down Syndrome data reveals consistent genome-wide dosage effects related to neurological processes ⬇️

artículo científico publicado en 2011

Molecular characterization of cultured adult human liver progenitor cells

artículo científico publicado en 2010

Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.

artículo científico publicado en 2017

Multiplexed hybridizations of positively charge-tagged peptide nucleic acids detected by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

artículo científico publicado en 2004

Network integration and modelling of dynamic drug responses at multi-omics levels

scientific article published on 15 October 2020

New evidence for genome-wide duplications at the origin of vertebrates using an amphioxus gene set and completed animal genomes

artículo científico publicado en 2003

Nodal signaling activates differentiation genes during zebrafish gastrulation

artículo científico

Oligonucleotide fingerprinting of arrayed genomic DNA sequences using LNA-modified hybridization probes

artículo científico publicado en 2007

Ortho2ExpressMatrix--a web server that interprets cross-species gene expression data by gene family information

artículo científico publicado en 2011

PWD/Ph-encoded genetic variants modulate the cellular Wnt/β-Catenin response to suppress ApcMin-triggered intestinal tumor formation

artículo científico publicado en 2020

Pathway deregulation and expression QTLs in response to Actinobacillus pleuropneumoniae infection in swine

artículo científico

Prediction in the face of uncertainty: a Monte Carlo-based approach for systems biology of cancer treatment

artículo científico publicado en 2012

Primary differentiation in the human blastocyst: comparative molecular portraits of inner cell mass and trophectoderm cells

artículo científico publicado en 2005

Proteomic and functional analysis of the mitotic Drosophila centrosome

artículo científico publicado en 2010

QSEA-modelling of genome-wide DNA methylation from sequencing enrichment experiments

artículo científico publicado en 2016

RNA-Seq provides new insights in the transcriptome responses induced by the carcinogen benzo[a]pyrene

artículo científico publicado en 2012

Resources, standards and tools for systems biology

artículo científico publicado en 2007

Reverse engineering of gene regulatory networks: a comparative study

artículo científico

Simulation of DNA array hybridization experiments and evaluation of critical parameters during subsequent image and data analysis

artículo científico publicado en 2002

Suppression of the transcription factor MSX1 gene delays bovine preimplantation embryo development in vitro

artículo científico publicado en 2010

Targeted high throughput sequencing in clinical cancer settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity

artículo científico publicado en 2011

The ConsensusPathDB interaction database: 2013 update

artículo científico publicado en 2012

The enzymatic activity of the VEGFR2 receptor for the biosynthesis of dinucleoside polyphosphates

artículo científico publicado en 2013

ToxDB: pathway-level interpretation of drug-treatment data

artículo científico publicado en 2016

Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome

artículo científico publicado en 2004

Transcriptional signature induced by a metastasis-promoting c-Src mutant in a human breast cell line

artículo científico publicado en 2016

Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models

artículo científico publicado en 2013

Transformation and other factors of the peptide mass spectrometry pairwise peak-list comparison process

artículo científico publicado en 2005

diXa: a data infrastructure for chemical safety assessment

artículo científico publicado en 2014

Lista de obras de Ralf Herwig

"4D Biology for health and disease" workshop report

A Systems Biology Approach for Identifying Hepatotoxicant Groups Based on Similarity in Mechanisms of Action and Chemical Structure

A gene expression map of human chromosome 21 orthologues in the mouse

A global view of gene expression in lithium and zinc treated sea urchin embryos: new components of gene regulatory networks

A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity

A second generation radiation hybrid map to aid the assembly of the bovine genome sequence

ARH-seq: identification of differential splicing in RNA-seq data

ARH: predicting splice variants from genome-wide data with modified entropy

Activation of AMP-activated protein kinase sensitizes lung cancer cells and H1299 xenografts to erlotinib

Age-specific hormonal decline is accompanied by transcriptional changes in human sebocytes in vitro

Aging of human sebocytes in vitro induced by exposure to a defined hormone environment

An integrative computational analysis provides evidence for FBN1-associated network deregulation in trisomy 21

An oligonucleotide fingerprint normalized and expressed sequence tag characterized zebrafish cDNA library

Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells

Analyzing and interpreting genome data at the network level with ConsensusPathDB

Cluster-based assessment of protein-protein interaction confidence

Comparative gene expression profiling by oligonucleotide fingerprinting ⬇️

Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage

Consensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cells

ConsensusPathDB--a database for integrating human functional interaction networks

ConsensusPathDB: toward a more complete picture of cell biology

Conserved molecular portraits of bovine and human blastocysts as a consequence of the transition from maternal to embryonic control of gene expression

Construction of a 'unigene' cDNA clone set by oligonucleotide fingerprinting allows access to 25 000 potential sugar beet genes

Construction of a pig physical interactome using sequence homology and a comprehensive reference human interactome

Cross-species hybridisation of human and bovine orthologous genes on high density cDNA microarrays

DEFOG: a practical scheme for deciphering families of genes

DIPSBC--data integration platform for systems biology collaborations

DNA-methylome analysis of mouse intestinal adenoma identifies a tumour-specific signature that is partly conserved in human colon cancer

Diet-induced gene expression of isolated pancreatic islets from a polygenic mouse model of the metabolic syndrome.

Dynamics of biological systems: role of systems biology in medical research

Establishment of T cell-specific and natural killer cell-specific unigene sets: towards high-throughput genomics of leukaemia.

Evaluation of database-derived pathway development for enabling biomarker discovery for hepatotoxicity

Evidence mining and novelty assessment of protein-protein interactions with the ConsensusPathDB plugin for Cytoscape

Exploring potential target genes of signaling pathways by predicting conserved transcription factor binding sites

Expression profiling and comparative genomics identify a conserved regulatory region controlling midline expression in the zebrafish embryo

GeNGe: systematic generation of gene regulatory networks

Gene expression variation in Down's syndrome mice allows prioritization of candidate genes

Generation, annotation, evolutionary analysis, and database integration of 20,000 unique sea urchin EST clusters

Human embryonic stem cell derived hepatocyte-like cells as a tool for in vitro hazard assessment of chemical carcinogenicity

Identification of QTL affecting resistance/susceptibility to acute Actinobacillus pleuropneumoniae infection in swine

Identification of marker genes for type 2 diabetes

Identification of nodal signaling targets by array analysis of induced complex probes

In silico identification of a core regulatory network of OCT4 in human embryonic stem cells using an integrated approach

IntScore: a web tool for confidence scoring of biological interactions

Integrated pathway-level analysis of transcriptomics and metabolomics data with IMPaLA.

Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells

Large-scale clustering of cDNA-fingerprinting data

MEDIPS: genome-wide differential coverage analysis of sequencing data derived from DNA enrichment experiments

Matrix metalloproteinases of epithelial origin in facial sebum of patients with acne and their regulation by isotretinoin

Meta-analysis approach identifies candidate genes and associated molecular networks for type-2 diabetes mellitus

Meta-analysis of heterogeneous Down Syndrome data reveals consistent genome-wide dosage effects related to neurological processes ⬇️

Molecular characterization of cultured adult human liver progenitor cells

Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.

Multiplexed hybridizations of positively charge-tagged peptide nucleic acids detected by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

Network integration and modelling of dynamic drug responses at multi-omics levels

New evidence for genome-wide duplications at the origin of vertebrates using an amphioxus gene set and completed animal genomes

Nodal signaling activates differentiation genes during zebrafish gastrulation

Oligonucleotide fingerprinting of arrayed genomic DNA sequences using LNA-modified hybridization probes

Ortho2ExpressMatrix--a web server that interprets cross-species gene expression data by gene family information

PWD/Ph-encoded genetic variants modulate the cellular Wnt/β-Catenin response to suppress ApcMin-triggered intestinal tumor formation

Pathway deregulation and expression QTLs in response to Actinobacillus pleuropneumoniae infection in swine

Prediction in the face of uncertainty: a Monte Carlo-based approach for systems biology of cancer treatment

Primary differentiation in the human blastocyst: comparative molecular portraits of inner cell mass and trophectoderm cells

Proteomic and functional analysis of the mitotic Drosophila centrosome

QSEA-modelling of genome-wide DNA methylation from sequencing enrichment experiments

RNA-Seq provides new insights in the transcriptome responses induced by the carcinogen benzo[a]pyrene

Resources, standards and tools for systems biology

Reverse engineering of gene regulatory networks: a comparative study

Simulation of DNA array hybridization experiments and evaluation of critical parameters during subsequent image and data analysis

Suppression of the transcription factor MSX1 gene delays bovine preimplantation embryo development in vitro

Targeted high throughput sequencing in clinical cancer settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity

The ConsensusPathDB interaction database: 2013 update

The enzymatic activity of the VEGFR2 receptor for the biosynthesis of dinucleoside polyphosphates

ToxDB: pathway-level interpretation of drug-treatment data

Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome

Transcriptional signature induced by a metastasis-promoting c-Src mutant in a human breast cell line

Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models

Transformation and other factors of the peptide mass spectrometry pairwise peak-list comparison process