Lista de obras - K G Smith - Dominio Público Uruguay

A CD8<sup>+</sup> NK cell transcriptomic signature associated with clinical outcome in relapsing remitting multiple sclerosis

artículo científico publicado en 2021

A blood-based prognostic biomarker in IBD

scientific article published on 27 April 2019

A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes

artículo científico publicado en 1998

A multicenter survey of rituximab therapy for refractory antineutrophil cytoplasmic antibody-associated vasculitis.

artículo científico publicado en 2009

A type I interferon transcriptional signature precedes autoimmunity in children genetically at risk for type 1 diabetes.

artículo científico publicado en 2014

Absence of hyperacute rejection and preservation of function in HDAF transgenic pig kidneys exposed to prolonged cold ischaemia

scientific article published on 01 August 2000

Affinity maturation of the primary response by V gene diversification.

artículo científico publicado en 1998

Alemtuzumab (CAMPATH 1H) induction therapy in cadaveric kidney transplantation--efficacy and safety at five years.

artículo científico publicado en 2005

Analysis of a wild mouse promoter variant reveals a novel role for FcγRIIb in the control of the germinal center and autoimmunity.

artículo científico publicado en 2012

Antibody repertoire analysis in polygenic autoimmune diseases

artículo científico publicado en 2018

Association Between Genetic Variation in FOXO3 and Reductions in Inflammation and Disease Activity in Inflammatory Polyarthritis

artículo científico publicado en 2016

Augmentin-induced jaundice with a fatal outcome

artículo científico publicado en 1992

Autoimmune-prone mice share a promoter haplotype associated with reduced expression and function of the Fc receptor FcgammaRII

artículo científico publicado en 2000

B Cell Fcγ Receptor IIb Modulates Atherosclerosis in Male and Female Mice by Controlling Adaptive Germinal Center and Innate B-1-Cell Responses

scientific article published on 16 May 2019

B cell inhibitory receptors and autoimmunity.

artículo científico publicado en 2003

B cells in glomerulonephritis: focus on lupus nephritis.

artículo científico publicado en 2007

Bcl-2 increases memory B cell recruitment but does not perturb selection in germinal centers.

artículo científico publicado en 1994

Belimumab in kidney transplantation: an experimental medicine, randomised, placebo-controlled phase 2 trial

artículo científico publicado en 2018

CAMPATH IH ALLOWS LOW-DOSE CYCLOSPORINE MONOTHERAPY IN 31 CADAVERIC RENAL ALLOGRAFT RECIPIENTS

artículo científico publicado en 1999

CD22 and autoimmune disease.

artículo científico

CD28 expression is required after T cell priming for helper T cell responses and protective immunity to infection.

artículo científico publicado en 2014

CTLA4Ig alters the course of autoimmune disease development in Lyn-/- mice

article

Combined Influence of B-Cell Receptor Rearrangement and Somatic Hypermutation on B-Cell Class-Switch Fate in Health and in Chronic Lymphocytic Leukemia

article

Comment on "The inhibiting Fc receptor for IgG, FcγRIIB, is a modifier of autoimmune susceptibility"

scientific article published on 01 December 2011

Comparison of gene expression microarray data with count-based RNA measurements informs microarray interpretation

artículo científico publicado en 2014

Correction: Lipid Anti-Lipid Antibody Responses Correlate with Disease Activity in Systemic Lupus Erythematosus.

artículo científico publicado en 2013

CrmA expression in T lymphocytes of transgenic mice inhibits CD95 (Fas/APO-1)-transduced apoptosis, but does not cause lymphadenopathy or autoimmune disease.

artículo científico publicado en 1996

Cross-phenotype analysis of Immunochip data identifies KDM4C as a relevant locus for the development of systemic vasculitis. ⬇️

artículo científico publicado en 2018

De-functioning polymorphism in the inhibitory receptor FcγRIIB does not impact upon kidney allograft survival

artículo científico publicado en 2014

Dendritic cell stimulation by mycobacterial Hsp70 is mediated through CCR5.

artículo científico publicado en 2006

Dependence of surface monoclonal antibody binding on dynamic changes in FcgammaRIIb expression

scientific article published on 24 January 2008

Differential signal transduction, membrane trafficking, and immune effector functions mediated by FcgammaRI versus FcgammaRIIa

scientific article published on 06 May 2009

Differential targeting of viral components by CD4+ versus CD8+ T lymphocytes in dengue virus infection.

artículo científico publicado en 2012

EROS mutations: decreased NADPH oxidase function and chronic granulomatous disease

artículo científico publicado en 2018

Effects of viral inhibitors of apoptosis in models of mammalian cell death

artículo científico publicado en 1996

Efficient inhibition of miR-155 function in vivo by peptide nucleic acids

artículo científico publicado en 2010

Emerging concepts in the pathogenesis of antineutrophil cytoplasmic antibody-associated vasculitis.

artículo científico publicado en 2015

Envenomation by the small-scaled snake: the world's most venomous snake

artículo científico publicado en 1992

Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity

artículo científico publicado en 2017

FAS is highly expressed in the germinal center but is not required for regulation of the B-cell response to antigen

artículo científico publicado en 1995

FcgammaRIIB in autoimmunity and infection: evolutionary and therapeutic implications.

scientific article published on May 2010

FcgammaRIIB, FcgammaRIIIB, and systemic lupus erythematosus.

artículo científico publicado en 2010

FcgammaRIIb balances efficient pathogen clearance and the cytokine-mediated consequences of sepsis.

artículo científico publicado en 2004

FcγRIIB and autoimmunity

artículo científico publicado en 2016

FcγRIIb controls bone marrow plasma cell persistence and apoptosis

scientific article published on 18 February 2007

FcγRIIb differentially regulates pre-immune and germinal center B cell tolerance in mouse and human

scientific article published on 29 April 2019

FcγRIIb inhibits immune complex-induced VEGF-A production and intranodal lymphangiogenesis

artículo científico publicado en 2014

Foxp3+ follicular regulatory T cells control the germinal center response.

artículo científico publicado en 2011

Genetic susceptibility to systemic lupus erythematosus protects against cerebral malaria in mice ⬇️

artículo científico publicado el 27 de diciembre de 2010

Genetic variation, Fcγ receptors, KIRs and infection: the evolution of autoimmunity.

artículo científico publicado en 2010

Genome-wide association studies in Crohn's disease: Past, present and future.

artículo científico publicado en 2018

Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease.

artículo científico publicado en 2017

Genome-wide methylation analyses of primary human leukocyte subsets identifies functionally important cell-type-specific hypomethylated regions.

artículo científico publicado en 2013

Germline selection shapes human mitochondrial DNA diversity

scientific article published on 23 May 2019

Growth of porcine kidneys in their native and xenograft environment

scientific article published on 01 May 2000

HSP70 peptide binding mutants separate antigen delivery from dendritic cell stimulation

artículo científico

How many memories does it take to make an SLE flare?

scientific article published on 01 July 2015

Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway

scientific article published on 12 September 2013

Human T-follicular helper and T-follicular regulatory cell maintenance is independent of germinal centers

artículo científico publicado en 2014

Human interleukin-2 receptor β mutations associated with defects in immunity and peripheral tolerance

scientific article published on 30 April 2019

Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes

artículo científico publicado en 2014

Inhibition of the B cell by CD22: a requirement for Lyn

artículo científico publicado en 1998

Insight into Genotype-Phenotype Associations through eQTL Mapping in Multiple Cell Types in Health and Immune-Mediated Disease

artículo científico publicado en 2016

Interleukin 4 reduces expression of inhibitory receptors on B cells and abolishes CD22 and Fc gamma RII-mediated B cell suppression.

artículo científico publicado en 2002

Leucocyte subset-specific type 1 interferon signatures in SLE and other immune-mediated diseases

artículo científico publicado en 2016

Leukocyte and serum S100A8/S100A9 expression reflects disease activity in ANCA-associated vasculitis and glomerulonephritis.

artículo científico publicado en 2013

Local Renal Autoantibody Production in Lupus Nephritis ⬇️

artículo científico publicado el 18 de noviembre de 2010

Long-term comparison of rituximab treatment for refractory systemic lupus erythematosus and vasculitis: Remission, relapse, and re-treatment

scientific article published on 01 September 2006

Loss of function of a lupus-associated FcγRIIb polymorphism through exclusion from lipid rafts

scientific article published on 18 September 2005

Loss of the interleukin-6 receptor causes immunodeficiency, atopy, and abnormal inflammatory responses

scientific article published on 24 June 2019

Lymphangitis carcinomatosa on renal biopsy

scientific article published on 01 January 1994

MT-HESS: an efficient Bayesian approach for simultaneous association detection in OMICS datasets, with application to eQTL mapping in multiple tissues

artículo científico publicado en 2015

Maintenance triple immunosuppression with cyclosporin A, mycophenolate sodium and steroids allows prolonged survival of primate recipients of hDAF porcine renal xenografts.

artículo científico publicado en 2003

Metabolic exhaustion in infection, cancer and autoimmunity.

artículo científico publicado en 2018

Metastatic endophthalmitis in dialysis patients

artículo científico publicado en 1995

Modules, networks and systems medicine for understanding disease and aiding diagnosis.

artículo científico publicado en 2014

NBEAL2 is required for neutrophil and NK cell function and pathogen defense

artículo científico publicado en 2017

Novel aspects of autoimmunity.

artículo científico publicado en 2016

PRedicting Outcomes For Crohn's dIsease using a moLecular biomarkEr (PROFILE): protocol for a multicentre, randomised, biomarker-stratified trial

artículo científico publicado en 2018

Patient stratification and genomics: flares, fizzlers and foxes.

artículo científico publicado en 2012

Physiological aspects of pig-to-primate renal xenotransplantation

scientific article published on 01 October 2001

Pregnancy-related anaemia in a haemodialysis patient treated with erythropoietin

scientific article published on 01 January 1993

Prevalence and clinical challenges among adults with primary immunodeficiency and recombination-activating gene deficiency. ⬇️

artículo científico publicado en 2018

Prognosis in autoimmune and infectious disease: new insights from genetics.

artículo científico publicado en 2014

Prope tolerance with induction using Campath 1H and low-dose cyclosporin monotherapy in 31 cadaveric renal allograft recipients

scientific article published on 01 March 2000

Randomized trial of enteric-coated mycophenolate sodium versus mycophenolate mofetil in multi-system autoimmune disease

artículo científico publicado en 2014

Receptor modulators of B-cell receptor signalling--CD19/CD22.

artículo científico publicado en 2000

Recurrent Kikuchi's disease

artículo científico publicado en 1992

Reduced monocyte and macrophage TNFSF15/TL1A expression is associated with susceptibility to inflammatory bowel disease

artículo científico publicado en 2018

Regulatory T cells and control of the germinal centre response

artículo científico publicado en 2014

Rituximab in Churg-Strauss syndrome.

artículo científico publicado en 2006

Siglec-G deficiency leads to more severe collagen-induced arthritis and earlier onset of lupus-like symptoms in MRL/lpr mice.

artículo científico publicado en 2014

Signalling lymphocyte activation molecule family member 9 is found on select subsets of antigen-presenting cells and promotes resistance to Salmonella infection

artículo científico publicado en 2020

Single-cell multi-omics analysis of the immune response in COVID-19

artículo científico publicado en 2021

Soluble antigen can cause enhanced apoptosis of germinal-centre B cells.

artículo científico publicado en 1995

Soluble antigen can impede affinity maturation and the germinal center reaction but enhance extrafollicular immunoglobulin production.

artículo científico publicado en 1995

Suppression of the humoral immune response by mycophenolate mofetil

scientific article published on 01 January 1998

Systemic lupus erythematosus-associated defects in the inhibitory receptor FcgammaRIIb reduce susceptibility to malaria.

artículo científico publicado en 2007

T cell activation by anti-CD3 antibodies: function of Fc receptors on B cell blasts, but not resting B cells, and CD18 on the responding T cells

artículo científico publicado en 1987

T cell activation by anti-T3 antibodies: comparison of IgG1 and IgG2b switch variants and direct evidence for accessory function of macrophage Fc receptors

artículo científico publicado en 1986

T cell exhaustion and immune-mediated disease-the potential for therapeutic exhaustion.

artículo científico publicado en 2016

T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection.

artículo científico publicado en 2015

T-cell exhaustion: understanding the interface of chronic viral and autoinflammatory diseases.

artículo científico publicado en 2016

Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network

artículo científico publicado en 2016

The B-cell response to protein antigens in immunity and transplantation

artículo científico publicado en 2008

The Contribution of Transcriptomics to Biomarker Development in Systemic Vasculitis and SLE.

artículo científico

The contribution of genetic variation and infection to the pathogenesis of ANCA-associated systemic vasculitis

artículo científico publicado en 2010

The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response ⬇️

artículo científico publicado el 2 de junio de 1997

The generation and maintenance of serum alloantibody.

artículo científico publicado en 2010

The immunopathology of ANCA-associated vasculitis

artículo científico publicado en 2014

The nervous spleen: The nervous spleen.

artículo científico publicado en 2008

The phenotype and fate of the antibody-forming cells of the splenic foci

scientific article published on 01 February 1996

Treatment of COVID-19 with remdesivir in the absence of humoral immunity: a case report

artículo científico publicado en 2020

Wild immunology: converging on the real world.

artículo científico publicado en 2011

bcl-2 transgene expression inhibits apoptosis in the germinal center and reveals differences in the selection of memory B cells and bone marrow antibody-forming cells

artículo científico publicado en 2000

miR-374a-5p regulates inflammatory genes and monocyte function in patients with inflammatory bowel disease

artículo científico publicado en 2022

Lista de obras de K G Smith

A CD8<sup>+</sup> NK cell transcriptomic signature associated with clinical outcome in relapsing remitting multiple sclerosis

A blood-based prognostic biomarker in IBD

A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes

A multicenter survey of rituximab therapy for refractory antineutrophil cytoplasmic antibody-associated vasculitis.

A type I interferon transcriptional signature precedes autoimmunity in children genetically at risk for type 1 diabetes.

Absence of hyperacute rejection and preservation of function in HDAF transgenic pig kidneys exposed to prolonged cold ischaemia

Affinity maturation of the primary response by V gene diversification.

Alemtuzumab (CAMPATH 1H) induction therapy in cadaveric kidney transplantation--efficacy and safety at five years.

Analysis of a wild mouse promoter variant reveals a novel role for FcγRIIb in the control of the germinal center and autoimmunity.

Antibody repertoire analysis in polygenic autoimmune diseases

Association Between Genetic Variation in FOXO3 and Reductions in Inflammation and Disease Activity in Inflammatory Polyarthritis

Augmentin-induced jaundice with a fatal outcome

Autoimmune-prone mice share a promoter haplotype associated with reduced expression and function of the Fc receptor FcgammaRII

B Cell Fcγ Receptor IIb Modulates Atherosclerosis in Male and Female Mice by Controlling Adaptive Germinal Center and Innate B-1-Cell Responses

B cell inhibitory receptors and autoimmunity.

B cells in glomerulonephritis: focus on lupus nephritis.

Bcl-2 increases memory B cell recruitment but does not perturb selection in germinal centers.

Belimumab in kidney transplantation: an experimental medicine, randomised, placebo-controlled phase 2 trial

CAMPATH IH ALLOWS LOW-DOSE CYCLOSPORINE MONOTHERAPY IN 31 CADAVERIC RENAL ALLOGRAFT RECIPIENTS

CD22 and autoimmune disease.

CD28 expression is required after T cell priming for helper T cell responses and protective immunity to infection.

CTLA4Ig alters the course of autoimmune disease development in Lyn-/- mice

Combined Influence of B-Cell Receptor Rearrangement and Somatic Hypermutation on B-Cell Class-Switch Fate in Health and in Chronic Lymphocytic Leukemia

Comment on "The inhibiting Fc receptor for IgG, FcγRIIB, is a modifier of autoimmune susceptibility"

Comparison of gene expression microarray data with count-based RNA measurements informs microarray interpretation

Correction: Lipid Anti-Lipid Antibody Responses Correlate with Disease Activity in Systemic Lupus Erythematosus.

CrmA expression in T lymphocytes of transgenic mice inhibits CD95 (Fas/APO-1)-transduced apoptosis, but does not cause lymphadenopathy or autoimmune disease.

Cross-phenotype analysis of Immunochip data identifies KDM4C as a relevant locus for the development of systemic vasculitis. ⬇️

De-functioning polymorphism in the inhibitory receptor FcγRIIB does not impact upon kidney allograft survival

Dendritic cell stimulation by mycobacterial Hsp70 is mediated through CCR5.

Dependence of surface monoclonal antibody binding on dynamic changes in FcgammaRIIb expression

Differential signal transduction, membrane trafficking, and immune effector functions mediated by FcgammaRI versus FcgammaRIIa

Differential targeting of viral components by CD4+ versus CD8+ T lymphocytes in dengue virus infection.

EROS mutations: decreased NADPH oxidase function and chronic granulomatous disease

Effects of viral inhibitors of apoptosis in models of mammalian cell death

Efficient inhibition of miR-155 function in vivo by peptide nucleic acids

Emerging concepts in the pathogenesis of antineutrophil cytoplasmic antibody-associated vasculitis.

Envenomation by the small-scaled snake: the world's most venomous snake

Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity

FAS is highly expressed in the germinal center but is not required for regulation of the B-cell response to antigen

FcgammaRIIB in autoimmunity and infection: evolutionary and therapeutic implications.

FcgammaRIIB, FcgammaRIIIB, and systemic lupus erythematosus.

FcgammaRIIb balances efficient pathogen clearance and the cytokine-mediated consequences of sepsis.

FcγRIIB and autoimmunity

FcγRIIb controls bone marrow plasma cell persistence and apoptosis

FcγRIIb differentially regulates pre-immune and germinal center B cell tolerance in mouse and human

FcγRIIb inhibits immune complex-induced VEGF-A production and intranodal lymphangiogenesis

Foxp3+ follicular regulatory T cells control the germinal center response.

Genetic susceptibility to systemic lupus erythematosus protects against cerebral malaria in mice ⬇️

Genetic variation, Fcγ receptors, KIRs and infection: the evolution of autoimmunity.

Genome-wide association studies in Crohn's disease: Past, present and future.

Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease.

Genome-wide methylation analyses of primary human leukocyte subsets identifies functionally important cell-type-specific hypomethylated regions.

Germline selection shapes human mitochondrial DNA diversity

Growth of porcine kidneys in their native and xenograft environment

HSP70 peptide binding mutants separate antigen delivery from dendritic cell stimulation

How many memories does it take to make an SLE flare?

Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway

Human T-follicular helper and T-follicular regulatory cell maintenance is independent of germinal centers

Human interleukin-2 receptor β mutations associated with defects in immunity and peripheral tolerance

Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes

Inhibition of the B cell by CD22: a requirement for Lyn

Insight into Genotype-Phenotype Associations through eQTL Mapping in Multiple Cell Types in Health and Immune-Mediated Disease

Interleukin 4 reduces expression of inhibitory receptors on B cells and abolishes CD22 and Fc gamma RII-mediated B cell suppression.

Leucocyte subset-specific type 1 interferon signatures in SLE and other immune-mediated diseases

Leukocyte and serum S100A8/S100A9 expression reflects disease activity in ANCA-associated vasculitis and glomerulonephritis.

Local Renal Autoantibody Production in Lupus Nephritis ⬇️

Long-term comparison of rituximab treatment for refractory systemic lupus erythematosus and vasculitis: Remission, relapse, and re-treatment

Loss of function of a lupus-associated FcγRIIb polymorphism through exclusion from lipid rafts

Loss of the interleukin-6 receptor causes immunodeficiency, atopy, and abnormal inflammatory responses

Lymphangitis carcinomatosa on renal biopsy

MT-HESS: an efficient Bayesian approach for simultaneous association detection in OMICS datasets, with application to eQTL mapping in multiple tissues

Maintenance triple immunosuppression with cyclosporin A, mycophenolate sodium and steroids allows prolonged survival of primate recipients of hDAF porcine renal xenografts.

Metabolic exhaustion in infection, cancer and autoimmunity.

Metastatic endophthalmitis in dialysis patients

Modules, networks and systems medicine for understanding disease and aiding diagnosis.

NBEAL2 is required for neutrophil and NK cell function and pathogen defense

Novel aspects of autoimmunity.

PRedicting Outcomes For Crohn's dIsease using a moLecular biomarkEr (PROFILE): protocol for a multicentre, randomised, biomarker-stratified trial