Lista de obras - Christopher A Reynolds - Dominio Público Uruguay

A Hydrogen-Bonded Polar Network in the Core of the Glucagon-Like Peptide-1 Receptor Is a Fulcrum for Biased Agonism: Lessons from Class B Crystal Structures

artículo científico publicado en 2015

A New Approach to Docking in the β2-Adrenergic Receptor That Exploits the Domain Structure of G-Protein-Coupled Receptors ⬇️

artículo científico publicado el 21 de noviembre de 1997

A multilayered approach to approximating solute polarization

artículo científico publicado en 2004

A prototype bioreductive DNA groove binding ligand

artículo científico publicado en 1991

Accurate numerical determination of Kohn-Sham potentials from electronic densities: I. Two-electron systems

article published in 1997

Addressing free fatty acid receptor 1 (FFAR1) activation using supervised molecular dynamics

artículo científico publicado en 2020

Assessing the effect of dynamics on the closed-loop protein-folding hypothesis

artículo científico publicado en 2013

Assessing the role of polarization in docking.

artículo científico publicado en 2008

Bioinformatics and molecular modelling approaches to GPCR oligomerization.

artículo científico publicado en 2009

Classical polarization in hybrid QM/MM methods

artículo científico publicado en 2006

Closed loop folding units from structural alignments: experimental foldons revisited.

artículo científico publicado en 2010

Computed redox potentials and the design of bioreductive agents ⬇️

artículo científico publicado el 7 de julio de 1988

Connectivity and binding-site recognition: applications relevant to drug design.

artículo científico publicado en 2010

Conservation of closed loops

artículo científico publicado en 2007

Correlated mutations amongst the external residues of G-protein coupled receptors ⬇️

artículo científico publicado el 1 de agosto de 1997

Correlated mutations and subtype specificity in the adrenergic receptor ⬇️

artículo científico publicado el 1 de agosto de 1997

Criteria for confirming sequence periodicity identified by Fourier transform analysis: application to GCR2, a candidate plant GPCR?

artículo científico publicado en 2007

Dimerization and domain swapping in G-protein-coupled receptors: a computational study

artículo científico publicado en 2000

Dimerization of G-protein-coupled receptors

artículo científico publicado en 2001

Extracellular loops 2 and 3 of the calcitonin receptor selectively modify agonist binding and efficacy.

artículo científico publicado en 2018

Genetically encoded photocross-linkers determine the biological binding site of exendin-4 peptide in the N-terminal domain of the intact human glucagon-like peptide-1 receptor (GLP-1R)

artículo científico publicado en 2017

Hypoxia-targeting copper bis(selenosemicarbazone) complexes: comparison with their sulfur analogues

scientific article published on 01 August 2003

Key interactions by conserved polar amino acids located at the transmembrane helical boundaries in Class B GPCRs modulate activation, effector specificity and biased signalling in the glucagon-like peptide-1 receptor

artículo científico publicado en 2016

Modeling GPCR active state conformations: The β2‐adrenergic receptor ⬇️

artículo científico publicado el 18 de febrero de 2011

Partial agonism improves the anti-hyperglycaemic efficacy of an oxyntomodulin-derived GLP-1R/GCGR co-agonist

artículo científico publicado en 2021

Potential energy surfaces from Kohn-Sham potentials

Quantitative measurement of protease ligand conformation.

artículo científico publicado en 2008

Rational drug design: binding free energy differences of carbonic anhydrase inhibitors

Receptor Activity-modifying Protein-directed G Protein Signaling Specificity for the Calcitonin Gene-related Peptide Family of Receptors

artículo científico publicado en 2016

Simulations on dimeric peptides: evidence for domain swapping in G-protein-coupled receptors? ⬇️

artículo científico publicado el 1 de agosto de 1997

Structure and dynamics of the active Gs-coupled human secretin receptor

scientific article published on 18 August 2020

Studies on the mechanism of hypoxic selectivity in copper bis(thiosemicarbazone) radiopharmaceuticals.

artículo científico publicado en 2002

The Extracellular Surface of the GLP-1 Receptor Is a Molecular Trigger for Biased Agonism

artículo científico publicado en 2016

Toward a consistent treatment of polarization in model QM/MM calculations.

artículo científico publicado en 2008

Towards new transition metal-based hypoxic selective agents for therapy and imaging

artículo científico publicado en 2001

Understanding the molecular functions of the second extracellular loop (ECL2) of the calcitonin gene-related peptide (CGRP) receptor using a comprehensive mutagenesis approach

artículo científico publicado en 2017

Lista de obras de Christopher A Reynolds

A Hydrogen-Bonded Polar Network in the Core of the Glucagon-Like Peptide-1 Receptor Is a Fulcrum for Biased Agonism: Lessons from Class B Crystal Structures

A New Approach to Docking in the β2-Adrenergic Receptor That Exploits the Domain Structure of G-Protein-Coupled Receptors ⬇️

A multilayered approach to approximating solute polarization

A prototype bioreductive DNA groove binding ligand

Accurate numerical determination of Kohn-Sham potentials from electronic densities: I. Two-electron systems

Addressing free fatty acid receptor 1 (FFAR1) activation using supervised molecular dynamics

Assessing the effect of dynamics on the closed-loop protein-folding hypothesis

Assessing the role of polarization in docking.

Bioinformatics and molecular modelling approaches to GPCR oligomerization.

Classical polarization in hybrid QM/MM methods

Closed loop folding units from structural alignments: experimental foldons revisited.

Computed redox potentials and the design of bioreductive agents ⬇️

Connectivity and binding-site recognition: applications relevant to drug design.

Conservation of closed loops

Correlated mutations amongst the external residues of G-protein coupled receptors ⬇️

Correlated mutations and subtype specificity in the adrenergic receptor ⬇️

Criteria for confirming sequence periodicity identified by Fourier transform analysis: application to GCR2, a candidate plant GPCR?

Dimerization and domain swapping in G-protein-coupled receptors: a computational study

Dimerization of G-protein-coupled receptors

Extracellular loops 2 and 3 of the calcitonin receptor selectively modify agonist binding and efficacy.

Genetically encoded photocross-linkers determine the biological binding site of exendin-4 peptide in the N-terminal domain of the intact human glucagon-like peptide-1 receptor (GLP-1R)

Hypoxia-targeting copper bis(selenosemicarbazone) complexes: comparison with their sulfur analogues

Key interactions by conserved polar amino acids located at the transmembrane helical boundaries in Class B GPCRs modulate activation, effector specificity and biased signalling in the glucagon-like peptide-1 receptor

Modeling GPCR active state conformations: The β2‐adrenergic receptor ⬇️

Partial agonism improves the anti-hyperglycaemic efficacy of an oxyntomodulin-derived GLP-1R/GCGR co-agonist

Potential energy surfaces from Kohn-Sham potentials

Quantitative measurement of protease ligand conformation.

Rational drug design: binding free energy differences of carbonic anhydrase inhibitors

Receptor Activity-modifying Protein-directed G Protein Signaling Specificity for the Calcitonin Gene-related Peptide Family of Receptors

Simulations on dimeric peptides: evidence for domain swapping in G-protein-coupled receptors? ⬇️

Structure and dynamics of the active Gs-coupled human secretin receptor

Studies on the mechanism of hypoxic selectivity in copper bis(thiosemicarbazone) radiopharmaceuticals.

The Extracellular Surface of the GLP-1 Receptor Is a Molecular Trigger for Biased Agonism

Toward a consistent treatment of polarization in model QM/MM calculations.

Towards new transition metal-based hypoxic selective agents for therapy and imaging

Understanding the molecular functions of the second extracellular loop (ECL2) of the calcitonin gene-related peptide (CGRP) receptor using a comprehensive mutagenesis approach