Lista de obras - Inke S. Näthke - Dominio Público Uruguay

A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin

scientific journal article

A Multicellular Model of Intestinal Crypt Buckling and Fission

artículo científico publicado en 2017

A role for the Adenomatous Polyposis Coli protein in chromosome segregation

artículo científico publicado en 2001

A two-dimensional model of the colonic crypt accounting for the role of the basement membrane and pericryptal fibroblast sheath

artículo científico publicado en 2012

APC at a glance.

artículo científico publicado en 2004

Acoustic Sensing and Ultrasonic Drug Delivery in Multimodal Theranostic Capsule Endoscopy

artículo científico publicado en 2017

Adenomatous polyposis coli and hypoxia-inducible factor-1{alpha} have an antagonistic connection

artículo científico publicado en 2010

Adenomatous polyposis coli on microtubule plus ends in cell extensions can promote microtubule net growth with or without EB1.

artículo científico publicado en 2006

Beta-catenin: a common target for the regulation of cell adhesion by Wnt-1 and Src signaling pathways.

artículo científico publicado en 1994

Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation

artículo científico publicado en 2001

Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways.

artículo científico publicado en 1997

Cancer Biology: APC Delivers Kiss of Death to Focal Adhesions.

artículo científico publicado en 2017

Catch and pull a microtubule: getting a grasp on the cortex

artículo científico publicado en 2001

Cell and tissue polarity in the intestinal tract during tumourigenesis: cells still know the right way up, but tissue organization is lost

artículo científico publicado en 2013

Cell polarity in development and cancer.

artículo científico publicado en 2007

Cell regulation by the Apc protein Apc as master regulator of epithelia.

scientific article published on 24 March 2008

Changes in cell and tissue organization in cancer of the breast and colon.

artículo científico publicado en 2013

Chir99021 and Valproic acid reduce the proliferative advantage of Apc mutant cells

artículo científico publicado en 2018

Combined changes in Wnt signaling response and contact inhibition induce altered proliferation in radiation-treated intestinal crypts.

artículo científico publicado en 2016

Computational models reveal a passive mechanism for cell migration in the crypt

artículo científico publicado en 2013

Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer. ⬇️

artículo científico publicado en 2018

Cytoskeleton out of the cupboard: colon cancer and cytoskeletal changes induced by loss of APC.

artículo científico publicado en 2006

DVC1 (C1orf124) recruits the p97 protein segregase to sites of DNA damage

artículo científico publicado en 2012

Defining interactions and distributions of cadherin and catenin complexes in polarized epithelial cells.

artículo científico publicado en 1994

Defining the role of APC in the mitotic spindle checkpoint in vivo: APC-deficient cells are resistant to Taxol.

artículo científico publicado en 2010

Developmental expression of catenins and associated proteins during submucosal gland morphogenesis in the airway.

artículo científico

Dynamics of cadherin/catenin complex formation: novel protein interactions and pathways of complex assembly

artículo científico publicado en 1994

Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo

artículo científico publicado en 2010

High-energy particle-induced tumorigenesis throughout the gastrointestinal tract

artículo científico

Identification of Endogenous Adenomatous Polyposis Coli Interaction Partners and β-Catenin-Independent Targets by Proteomics

scientific article published on 03 June 2019

Increased variability in Apc(Min)/+ intestinal tissue can be measured with microultrasound.

artículo científico publicado en 2016

Inke Nathke: The ABCs of APC. Interview by Caitlin Sedwick.

artículo científico publicado en 2010

Interactions and functions of the adenomatous polyposis coli (APC) protein at a glance.

artículo científico publicado en 2013

Interkinetic nuclear migration and basal tethering facilitates post-mitotic daughter separation in intestinal organoids

artículo científico publicado en 2017

Lack of adenomatous polyposis coli protein correlates with a decrease in cell migration and overall changes in microtubule stability

artículo científico publicado en 2007

Lgr5+ intestinal stem cells reside in an unlicensed G1 phase.

artículo científico publicado en 2018

Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis

artículo científico publicado en 2007

Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration

scientific journal article

Loss of adenomatous polyposis coli function renders intestinal epithelial cells resistant to the cytokine IL-22

artículo científico publicado en 2019

Microtubule assembly by the Apc protein is regulated by importin-beta--RanGTP.

artículo científico publicado en 2010

Novel self-association of the APC molecule affects APC clusters and cell migration.

artículo científico publicado en 2008

Open microscopy environment and findspots: integrating image informatics with quantitative multidimensional image analysis.

artículo científico publicado en 2006

Opposing actions of the synapse-associated protein of 97-kDa molecular weight (SAP97) and Disrupted in Schizophrenia 1 (DISC1) on Wnt/β-catenin signaling.

artículo científico publicado en 2016

Paneth Cell-Rich Regions Separated by a Cluster of Lgr5+ Cells Initiate Crypt Fission in the Intestinal Stem Cell Niche.

artículo científico publicado en 2016

Preparation of wholemount mouse intestine for high-resolution three-dimensional imaging using two-photon microscopy.

artículo científico publicado en 2009

Promoting microtubule assembly: A hypothesis for the functional significance of the +TIP network.

artículo científico publicado en 2014

Redefining the subcellular location and transport of APC: new insights using a panel of antibodies.

artículo científico publicado en 2005

SAP97 Binding Partner CRIPT Promotes Dendrite Growth In Vitro and In Vivo.

artículo científico publicado en 2017

Spindle orientation bias in gut epithelial stem cell compartments is lost in precancerous tissue.

artículo científico publicado en 2010

Stem cell decisions: a twist of fate or a niche market?

artículo científico

The adenomatous polyposis coli protein contributes to normal compaction of mitotic chromatin

artículo científico publicado en 2012

The adenomatous polyposis coli protein is required for the formation of robust spindles formed in CSF Xenopus extracts.

artículo científico publicado en 2004

The adenomatous polyposis coli protein unambiguously localizes to microtubule plus ends and is involved in establishing parallel arrays of microtubule bundles in highly polarized epithelial cells

artículo científico publicado en 2002

The adenomatous polyposis coli protein: the Achilles heel of the gut epithelium.

artículo científico publicado en 2004

The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration.

artículo científico publicado en 1996

The calcium-binding site of clathrin light chains.

artículo científico publicado en 1990

The microtubule poison vinorelbine kills cells independently of mitotic arrest and targets cells lacking the APC tumour suppressor more effectively

artículo científico publicado en 2012

The tumor suppressor adenomatous polyposis coli controls the direction in which a cell extrudes from an epithelium

artículo científico publicado en 2011

Tumor-associated NH2-terminal fragments are the most stable part of the adenomatous polyposis coli protein and can be regulated by interactions with COOH-terminal domains.

artículo científico publicado en 2005

Tumorigenic fragments of APC cause dominant defects in directional cell migration in multiple model systems

artículo científico publicado en 2012

Ultrasound capsule endoscopy: sounding out the future.

artículo científico publicado en 2017

Ultrasound mediated delivery of quantum dots from a proof of concept capsule endoscope to the gastrointestinal wall

scientific article published on 28 January 2021

Lista de obras de Inke S. Näthke

A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin

A Multicellular Model of Intestinal Crypt Buckling and Fission

A role for the Adenomatous Polyposis Coli protein in chromosome segregation

A two-dimensional model of the colonic crypt accounting for the role of the basement membrane and pericryptal fibroblast sheath

APC at a glance.

Acoustic Sensing and Ultrasonic Drug Delivery in Multimodal Theranostic Capsule Endoscopy

Adenomatous polyposis coli and hypoxia-inducible factor-1{alpha} have an antagonistic connection

Adenomatous polyposis coli on microtubule plus ends in cell extensions can promote microtubule net growth with or without EB1.

Beta-catenin: a common target for the regulation of cell adhesion by Wnt-1 and Src signaling pathways.

Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation

Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways.

Cancer Biology: APC Delivers Kiss of Death to Focal Adhesions.

Catch and pull a microtubule: getting a grasp on the cortex

Cell and tissue polarity in the intestinal tract during tumourigenesis: cells still know the right way up, but tissue organization is lost

Cell polarity in development and cancer.

Cell regulation by the Apc protein Apc as master regulator of epithelia.

Changes in cell and tissue organization in cancer of the breast and colon.

Chir99021 and Valproic acid reduce the proliferative advantage of Apc mutant cells

Combined changes in Wnt signaling response and contact inhibition induce altered proliferation in radiation-treated intestinal crypts.

Computational models reveal a passive mechanism for cell migration in the crypt

Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer. ⬇️

Cytoskeleton out of the cupboard: colon cancer and cytoskeletal changes induced by loss of APC.

DVC1 (C1orf124) recruits the p97 protein segregase to sites of DNA damage

Defining interactions and distributions of cadherin and catenin complexes in polarized epithelial cells.

Defining the role of APC in the mitotic spindle checkpoint in vivo: APC-deficient cells are resistant to Taxol.

Developmental expression of catenins and associated proteins during submucosal gland morphogenesis in the airway.

Dynamics of cadherin/catenin complex formation: novel protein interactions and pathways of complex assembly

Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo

High-energy particle-induced tumorigenesis throughout the gastrointestinal tract

Identification of Endogenous Adenomatous Polyposis Coli Interaction Partners and β-Catenin-Independent Targets by Proteomics

Increased variability in Apc(Min)/+ intestinal tissue can be measured with microultrasound.

Inke Nathke: The ABCs of APC. Interview by Caitlin Sedwick.

Interactions and functions of the adenomatous polyposis coli (APC) protein at a glance.

Interkinetic nuclear migration and basal tethering facilitates post-mitotic daughter separation in intestinal organoids

Lack of adenomatous polyposis coli protein correlates with a decrease in cell migration and overall changes in microtubule stability

Lgr5+ intestinal stem cells reside in an unlicensed G1 phase.

Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis

Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration

Loss of adenomatous polyposis coli function renders intestinal epithelial cells resistant to the cytokine IL-22

Microtubule assembly by the Apc protein is regulated by importin-beta--RanGTP.

Novel self-association of the APC molecule affects APC clusters and cell migration.

Open microscopy environment and findspots: integrating image informatics with quantitative multidimensional image analysis.

Opposing actions of the synapse-associated protein of 97-kDa molecular weight (SAP97) and Disrupted in Schizophrenia 1 (DISC1) on Wnt/β-catenin signaling.

Paneth Cell-Rich Regions Separated by a Cluster of Lgr5+ Cells Initiate Crypt Fission in the Intestinal Stem Cell Niche.

Preparation of wholemount mouse intestine for high-resolution three-dimensional imaging using two-photon microscopy.

Promoting microtubule assembly: A hypothesis for the functional significance of the +TIP network.

Redefining the subcellular location and transport of APC: new insights using a panel of antibodies.

SAP97 Binding Partner CRIPT Promotes Dendrite Growth In Vitro and In Vivo.

Spindle orientation bias in gut epithelial stem cell compartments is lost in precancerous tissue.

Stem cell decisions: a twist of fate or a niche market?

The adenomatous polyposis coli protein contributes to normal compaction of mitotic chromatin

The adenomatous polyposis coli protein is required for the formation of robust spindles formed in CSF Xenopus extracts.

The adenomatous polyposis coli protein unambiguously localizes to microtubule plus ends and is involved in establishing parallel arrays of microtubule bundles in highly polarized epithelial cells

The adenomatous polyposis coli protein: the Achilles heel of the gut epithelium.

The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration.

The calcium-binding site of clathrin light chains.

The microtubule poison vinorelbine kills cells independently of mitotic arrest and targets cells lacking the APC tumour suppressor more effectively

The tumor suppressor adenomatous polyposis coli controls the direction in which a cell extrudes from an epithelium

Tumor-associated NH2-terminal fragments are the most stable part of the adenomatous polyposis coli protein and can be regulated by interactions with COOH-terminal domains.

Tumorigenic fragments of APC cause dominant defects in directional cell migration in multiple model systems

Ultrasound capsule endoscopy: sounding out the future.

Ultrasound mediated delivery of quantum dots from a proof of concept capsule endoscope to the gastrointestinal wall