Lista de obras - Daniel Coombs - Dominio Público Uruguay

A biophysical model of cell adhesion mediated by immunoadhesin drugs and antibodies

artículo científico publicado en 2011

A hidden Markov model for single particle tracks quantifies dynamic interactions between LFA-1 and the actin cytoskeleton

artículo científico publicado en 2009

A novel Bayesian approach to predicting reductions in HIV incidence following increased testing interventions among gay, bisexual and other men who have sex with men in Vancouver, Canada.

artículo científico publicado en 2018

A role for rebinding in rapid and reliable T cell responses to antigen

artículo científico publicado en 2009

A stochastic model of latently infected cell reactivation and viral blip generation in treated HIV patients

artículo científico publicado en 2011

A theoretical and experimental study of competition between solution and surface receptors for ligand in a Biacore flow cell.

artículo científico publicado en 2006

Activated TCRs remain marked for internalization after dissociation from pMHC

artículo científico publicado en 2002

An age-structured model of hiv infection that allows for variations in the production rate of viral particles and the death rate of productively infected cells.

artículo científico publicado en 2004

Analysis of membrane-localized binding kinetics with FRAP.

artículo científico publicado en 2008

Analysis of peptide/MHC-induced TCR downregulation: deciphering the triggering kinetics.

artículo científico publicado en 2006

Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation

artículo científico publicado en 2011

Applied stretch initiates directional invasion through the action of Rap1 GTPase as a tension sensor.

artículo científico publicado en 2016

Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and B cell activation

artículo científico publicado en 2019

Assessing the optimal virulence of malaria-targeting mosquito pathogens: a mathematical study of engineered Metarhizium anisopliae

artículo científico publicado en 2014

Asymptotic analysis of first passage time problems inspired by ecology.

artículo científico publicado en 2014

Conditions for eradicating hepatitis C in people who inject drugs: A fibrosis aware model of hepatitis C virus transmission.

artículo científico publicado en 2016

Correction: The Impact of Implementing a Test, Treat and Retain HIV Prevention Strategy in Atlanta among Black Men Who Have Sex with Men with a History of Incarceration: A Mathematical Model

artículo científico publicado en 2015

Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time

artículo científico publicado en 2010

Design Parameters for Granzyme-Mediated Cytotoxic Lymphocyte Target-Cell Killing and Specificity

artículo científico publicado en 2015

Distribution of take-home opioid antagonist kits during a synthetic opioid epidemic in British Columbia, Canada: a modelling study.

artículo científico publicado en 2018

Effects of intracellular calcium and actin cytoskeleton on TCR mobility measured by fluorescence recovery

artículo científico publicado en 2008

Effects of spatiotemporal HSV-2 lesion dynamics and antiviral treatment on the risk of HIV-1 acquisition.

artículo científico publicado en 2018

Effects of the geometry of the immunological synapse on the delivery of effector molecules.

artículo científico publicado en 2004

Equilibrium thermodynamics of cell-cell adhesion mediated by multiple ligand-receptor pairs

artículo científico publicado en 2004

Erratum: Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor.

artículo científico publicado en 2015

Evaluating the importance of within- and between-host selection pressures on the evolution of chronic pathogens

artículo científico publicado en 2007

Improving parameter estimation for cell surface FRAP data

artículo científico publicado en 2007

In vivo quantitative analysis of Talin turnover in response to force.

artículo científico publicado en 2015

In vivo regulation of integrin turnover by outside-in activation

artículo científico publicado en 2016

Kinetic proofreading model.

artículo científico publicado en 2008

Limitations of Qdot labelling compared to directly-conjugated probes for single particle tracking of B cell receptor mobility

artículo científico publicado en 2017

Mechanical force regulates integrin turnover in Drosophila in vivo.

artículo científico publicado en 2012

Modeling within-host evolution of HIV: mutation, competition and strain replacement.

artículo científico publicado en 2007

Modelling the combined impact of interventions in averting deaths during a synthetic-opioid overdose epidemic

scientific article published on 28 June 2019

On the duration of the period between exposure to HIV and detectable infection

artículo científico publicado en 2017

Optimal viral production

artículo científico publicado en 2003

Optimizing within-host viral fitness: infected cell lifespan and virion production rate

scientific article published on 01 July 2004

Periodic chirality transformations propagating on bacterial flagella

artículo científico publicado en 2002

Probability of a false-negative HIV antibody test result during the window period: a tool for pre- and post-test counselling

artículo científico

Quantification and modeling of tripartite CD2-, CD58FC chimera (alefacept)-, and CD16-mediated cell adhesion

artículo científico publicado en 2007

Quantifying the impact of COVID-19 control measures using a Bayesian model of physical distancing

scientific article published on 03 December 2020

Reverse engineering an amyloid aggregation pathway with dimensional analysis and scaling.

artículo científico publicado en 2011

SIR-Network Model and Its Application to Dengue Fever

article

Stochastic Dynamics of the Latently Infected Cell Reservoir During HIV Infection

article

Sustained Reduction in Sexual Behavior that May Pose a Risk of HIV Transmission Following Diagnosis During Early HIV Infection Among Gay Men in Vancouver, British Columbia.

artículo científico publicado en 2017

T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell.

artículo científico publicado en 2005

The Impact of Implementing a Test, Treat and Retain HIV Prevention Strategy in Atlanta among Black Men Who Have Sex with Men with a History of Incarceration: A Mathematical Model

artículo científico publicado en 2015

The space and time frames of T cell activation at the immunological synapse ⬇️

artículo científico publicado el 14 de octubre de 2010

Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor.

artículo científico publicado en 2015

Vaccination against 2009 pandemic H1N1 in a population dynamical model of Vancouver, Canada: timing is everything

artículo científico publicado en 2011

Lista de obras de Daniel Coombs

A biophysical model of cell adhesion mediated by immunoadhesin drugs and antibodies

A hidden Markov model for single particle tracks quantifies dynamic interactions between LFA-1 and the actin cytoskeleton

A novel Bayesian approach to predicting reductions in HIV incidence following increased testing interventions among gay, bisexual and other men who have sex with men in Vancouver, Canada.

A role for rebinding in rapid and reliable T cell responses to antigen

A stochastic model of latently infected cell reactivation and viral blip generation in treated HIV patients

A theoretical and experimental study of competition between solution and surface receptors for ligand in a Biacore flow cell.

Activated TCRs remain marked for internalization after dissociation from pMHC

An age-structured model of hiv infection that allows for variations in the production rate of viral particles and the death rate of productively infected cells.

Analysis of membrane-localized binding kinetics with FRAP.

Analysis of peptide/MHC-induced TCR downregulation: deciphering the triggering kinetics.

Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation

Applied stretch initiates directional invasion through the action of Rap1 GTPase as a tension sensor.

Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and B cell activation

Assessing the optimal virulence of malaria-targeting mosquito pathogens: a mathematical study of engineered Metarhizium anisopliae

Asymptotic analysis of first passage time problems inspired by ecology.

Conditions for eradicating hepatitis C in people who inject drugs: A fibrosis aware model of hepatitis C virus transmission.

Correction: The Impact of Implementing a Test, Treat and Retain HIV Prevention Strategy in Atlanta among Black Men Who Have Sex with Men with a History of Incarceration: A Mathematical Model

Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time

Design Parameters for Granzyme-Mediated Cytotoxic Lymphocyte Target-Cell Killing and Specificity

Distribution of take-home opioid antagonist kits during a synthetic opioid epidemic in British Columbia, Canada: a modelling study.

Effects of intracellular calcium and actin cytoskeleton on TCR mobility measured by fluorescence recovery

Effects of spatiotemporal HSV-2 lesion dynamics and antiviral treatment on the risk of HIV-1 acquisition.

Effects of the geometry of the immunological synapse on the delivery of effector molecules.

Equilibrium thermodynamics of cell-cell adhesion mediated by multiple ligand-receptor pairs

Erratum: Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor.

Evaluating the importance of within- and between-host selection pressures on the evolution of chronic pathogens

Improving parameter estimation for cell surface FRAP data

In vivo quantitative analysis of Talin turnover in response to force.

In vivo regulation of integrin turnover by outside-in activation

Kinetic proofreading model.

Limitations of Qdot labelling compared to directly-conjugated probes for single particle tracking of B cell receptor mobility

Mechanical force regulates integrin turnover in Drosophila in vivo.

Modeling within-host evolution of HIV: mutation, competition and strain replacement.

Modelling the combined impact of interventions in averting deaths during a synthetic-opioid overdose epidemic

On the duration of the period between exposure to HIV and detectable infection

Optimal viral production

Optimizing within-host viral fitness: infected cell lifespan and virion production rate

Periodic chirality transformations propagating on bacterial flagella

Probability of a false-negative HIV antibody test result during the window period: a tool for pre- and post-test counselling

Quantification and modeling of tripartite CD2-, CD58FC chimera (alefacept)-, and CD16-mediated cell adhesion

Quantifying the impact of COVID-19 control measures using a Bayesian model of physical distancing

Reverse engineering an amyloid aggregation pathway with dimensional analysis and scaling.

SIR-Network Model and Its Application to Dengue Fever

Stochastic Dynamics of the Latently Infected Cell Reservoir During HIV Infection

Sustained Reduction in Sexual Behavior that May Pose a Risk of HIV Transmission Following Diagnosis During Early HIV Infection Among Gay Men in Vancouver, British Columbia.

T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell.

The Impact of Implementing a Test, Treat and Retain HIV Prevention Strategy in Atlanta among Black Men Who Have Sex with Men with a History of Incarceration: A Mathematical Model

The space and time frames of T cell activation at the immunological synapse ⬇️

Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor.

Vaccination against 2009 pandemic H1N1 in a population dynamical model of Vancouver, Canada: timing is everything