Lista de obras - Nicholas M. Kanaan - Dominio Público Uruguay

A method for combining RNAscope in situ hybridization with immunohistochemistry in thick free-floating brain sections and primary neuronal cultures

artículo científico publicado en 2015

Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain

artículo científico publicado en 2019

Age-related changes in dopamine transporters and accumulation of 3-nitrotyrosine in rhesus monkey midbrain dopamine neurons: relevance in selective neuronal vulnerability to degeneration

artículo científico publicado en 2008

Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates ⬇️

artículo científico publicado el 18 de mayo de 2011

Aging Does Not Affect Axon Initial Segment Structure and Somatic Localization of Tau Protein in Hippocampal Neurons of Fischer 344 Rats.

artículo científico

Aging and Parkinson's disease: Different sides of the same coin?

artículo científico publicado en 2017

Analysis of isoform-specific tau aggregates suggests a common toxic mechanism involving similar pathological conformations and axonal transport inhibition

artículo científico publicado en 2016

Axonal Degeneration in Tauopathies: Disease Relevance and Underlying Mechanisms

artículo científico publicado en 2017

Axonal degeneration in Alzheimer's disease: when signaling abnormalities meet the axonal transport system.

artículo científico

Axonal transport defects in neurodegenerative diseases

scientific article published on October 2009

Calcium dysregulation contributes to neurodegeneration in FTLD patient iPSC-derived neurons

artículo científico publicado en 2016

Characterization of prefibrillar Tau oligomers in vitro and in Alzheimer disease.

artículo científico publicado en 2011

Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration

artículo científico publicado en 2018

Exogenous erythropoietin provides neuroprotection of grafted dopamine neurons in a rodent model of Parkinson's disease.

artículo científico publicado en 2005

Exposure of the Amino Terminus of Tau Is a Pathological Event in Multiple Tauopathies.

artículo científico publicado en 2017

Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory

artículo científico publicado en 2016

Gene Therapy Models of Alzheimer's Disease and Other Dementias

artículo científico publicado en 2016

Heat shock protein 70 prevents both tau aggregation and the inhibitory effects of preexisting tau aggregates on fast axonal transport.

artículo científico publicado en 2011

Homocysteine Increases Tau Phosphorylation, Truncation and Oligomerization.

artículo científico publicado en 2018

Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration

artículo científico publicado en 2015

Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.

artículo científico publicado en 2018

Liquid-liquid phase separation induces pathogenic tau conformations in vitro

artículo científico publicado en 2020

Loss of Functional Alpha-Synuclein: A Toxic Event in Parkinson's Disease? ⬇️

artículo científico publicado el 1 de enero de 2012

Novel Non-phosphorylated Serine 9/21 GSK3β/α Antibodies: Expanding the Tools for Studying GSK3 Regulation

artículo científico publicado en 2016

Pathogenic Forms of Tau Inhibit Kinesin-Dependent Axonal Transport through a Mechanism Involving Activation of Axonal Phosphotransferases ⬇️

artículo científico publicado el 6 de julio de 2011

Pathological conformations involving the amino terminus of tau occur early in Alzheimer's disease and are differentially detected by monoclonal antibodies.

artículo científico publicado en 2016

Peroxynitrite-induced nitrative and oxidative modifications alter tau filament formation.

artículo científico publicado en 2011

Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport.

artículo científico publicado en 2011

Pioglitazone prevents tau oligomerization.

artículo científico publicado en 2016

Production of recombinant tau oligomers in vitro

artículo científico publicado en 2017

Progression of tau pathology within cholinergic nucleus basalis neurons in chronic traumatic encephalopathy: A chronic effects of neurotrauma consortium study

artículo científico publicado en 2016

Protein homeostasis gene dysregulation in pretangle-bearing nucleus basalis neurons during the progression of Alzheimer's disease

artículo científico publicado en 2016

Pseudophosphorylation of tau at S422 enhances SDS-stable dimer formation and impairs both anterograde and retrograde fast axonal transport

artículo científico publicado en 2016

Quantitative and semi-quantitative measurements of axonal degeneration in tissue and primary neuron cultures

artículo científico publicado en 2016

Rationally Engineered AAV Capsids Improve Transduction and Volumetric Spread in the CNS

artículo científico publicado en 2017

Recombinant adenoassociated virus 2/5-mediated gene transfer is reduced in the aged rat midbrain

artículo científico publicado en 2014

Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo

artículo científico publicado en 2017

Soluble pre-fibrillar tau and β-amyloid species emerge in early human Alzheimer's disease and track disease progression and cognitive decline.

scientific article published on 21 October 2016

Tau Kinetics in Neurons and the Human Central Nervous System

artículo científico publicado en 2018

Tau Kinetics in Neurons and the Human Central Nervous System

scientific article published on 01 May 2018

Tau Oligomer Pathology in Nucleus Basalis Neurons During the Progression of Alzheimer Disease

artículo científico publicado en 2018

Tau Phosphorylation is Impacted by Rare AKAP9 Mutations Associated with Alzheimer Disease in African Americans

artículo científico publicado en 2018

The longitudinal transcriptomic response of the substantia nigra to intrastriatal 6-hydroxydopamine reveals significant upregulation of regeneration-associated genes

artículo científico publicado en 2015

Lista de obras de Nicholas M. Kanaan

A method for combining RNAscope in situ hybridization with immunohistochemistry in thick free-floating brain sections and primary neuronal cultures

Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain

Age-related changes in dopamine transporters and accumulation of 3-nitrotyrosine in rhesus monkey midbrain dopamine neurons: relevance in selective neuronal vulnerability to degeneration

Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates ⬇️

Aging Does Not Affect Axon Initial Segment Structure and Somatic Localization of Tau Protein in Hippocampal Neurons of Fischer 344 Rats.

Aging and Parkinson's disease: Different sides of the same coin?

Analysis of isoform-specific tau aggregates suggests a common toxic mechanism involving similar pathological conformations and axonal transport inhibition

Axonal Degeneration in Tauopathies: Disease Relevance and Underlying Mechanisms

Axonal degeneration in Alzheimer's disease: when signaling abnormalities meet the axonal transport system.

Axonal transport defects in neurodegenerative diseases

Calcium dysregulation contributes to neurodegeneration in FTLD patient iPSC-derived neurons

Characterization of prefibrillar Tau oligomers in vitro and in Alzheimer disease.

Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration

Exogenous erythropoietin provides neuroprotection of grafted dopamine neurons in a rodent model of Parkinson's disease.

Exposure of the Amino Terminus of Tau Is a Pathological Event in Multiple Tauopathies.

Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory

Gene Therapy Models of Alzheimer's Disease and Other Dementias

Heat shock protein 70 prevents both tau aggregation and the inhibitory effects of preexisting tau aggregates on fast axonal transport.

Homocysteine Increases Tau Phosphorylation, Truncation and Oligomerization.

Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration

Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.

Liquid-liquid phase separation induces pathogenic tau conformations in vitro

Loss of Functional Alpha-Synuclein: A Toxic Event in Parkinson's Disease? ⬇️

Novel Non-phosphorylated Serine 9/21 GSK3β/α Antibodies: Expanding the Tools for Studying GSK3 Regulation

Pathogenic Forms of Tau Inhibit Kinesin-Dependent Axonal Transport through a Mechanism Involving Activation of Axonal Phosphotransferases ⬇️

Pathological conformations involving the amino terminus of tau occur early in Alzheimer's disease and are differentially detected by monoclonal antibodies.

Peroxynitrite-induced nitrative and oxidative modifications alter tau filament formation.

Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport.

Pioglitazone prevents tau oligomerization.

Production of recombinant tau oligomers in vitro

Progression of tau pathology within cholinergic nucleus basalis neurons in chronic traumatic encephalopathy: A chronic effects of neurotrauma consortium study

Protein homeostasis gene dysregulation in pretangle-bearing nucleus basalis neurons during the progression of Alzheimer's disease

Pseudophosphorylation of tau at S422 enhances SDS-stable dimer formation and impairs both anterograde and retrograde fast axonal transport

Quantitative and semi-quantitative measurements of axonal degeneration in tissue and primary neuron cultures

Rationally Engineered AAV Capsids Improve Transduction and Volumetric Spread in the CNS

Recombinant adenoassociated virus 2/5-mediated gene transfer is reduced in the aged rat midbrain

Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo

Soluble pre-fibrillar tau and β-amyloid species emerge in early human Alzheimer's disease and track disease progression and cognitive decline.

Tau Kinetics in Neurons and the Human Central Nervous System

Tau Kinetics in Neurons and the Human Central Nervous System

Tau Oligomer Pathology in Nucleus Basalis Neurons During the Progression of Alzheimer Disease

Tau Phosphorylation is Impacted by Rare AKAP9 Mutations Associated with Alzheimer Disease in African Americans

The longitudinal transcriptomic response of the substantia nigra to intrastriatal 6-hydroxydopamine reveals significant upregulation of regeneration-associated genes