Lista de obras - Michael J Stocks - Dominio Público Uruguay

A practical method for targeted library design balancing lead-like properties with diversity

artículo científico publicado en 2009

Antagonists of the P2X(7) receptor. From lead identification to drug development.

artículo científico publicado en 2009

Antitumour benzothiazoles. Part 32: DNA adducts and double strand breaks correlate with activity; synthesis of 5F203 hydrogels for local delivery

artículo científico publicado en 2015

CXCL17 is an allosteric inhibitor of CXCR4 through a mechanism of action involving glycosaminoglycans

artículo científico publicado en 2024

Class 1 PI3K Clinical Candidates and Recent Inhibitor Design Strategies: A Medicinal Chemistry Perspective

scientific article published on 24 December 2018

Correction to Synthesis and Evaluation of the First Fluorescent Antagonists of the Human P2Y2 Receptor Based on AR-C118925.

artículo científico publicado en 2018

Design and Elaboration of a Tractable Tricyclic Scaffold To Synthesize Druglike Inhibitors of Dipeptidyl Peptidase-4 (DPP-4), Antagonists of the C-C Chemokine Receptor Type 5 (CCR5), and Highly Potent and Selective Phosphoinositol-3 Kinase δ (PI3Kδ)

artículo científico publicado en 2017

Design driven HtL: The discovery and synthesis of new high efficacy β₂-agonists.

artículo científico publicado en 2011

Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists.

artículo científico publicado en 2017

Discovery of AZD3199, An Inhaled Ultralong Acting β2 Receptor Agonist with Rapid Onset of Action.

artículo científico publicado en 2014

Drug-like Antagonists of P2Y Receptors-From Lead Identification to Drug Development

artículo científico publicado en 2016

Efficient and regiospecific one-pot synthesis of substituted 1,2,4-triazoles

artículo científico publicado en 2004

From UTP to AR-C118925, the discovery of a potent non nucleotide antagonist of the P2Y2 receptor.

artículo científico publicado en 2017

In Silico and in Vitro-Guided Identification of Inhibitors of Alkylquinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa

artículo científico publicado en 2018

Ipratropium is 'luminally recycled' by an inter-play between apical uptake and efflux transporters in Calu-3 bronchial epithelial cell layers.

artículo científico

Linifanib--a multi-targeted receptor tyrosine kinase inhibitor and a low molecular weight gelator

artículo científico publicado en 2015

Organocatalytic enantioselective one-pot four-component ugi-type multicomponent reaction for the synthesis of epoxy-tetrahydropyrrolo[3,4-b]pyridin-5-ones

scientific article published on 28 August 2012

Preparation and structural analysis of (±)-cis-ethyl 2-sulfanylidenedecahydro-1,6-naphthyridine-6-carboxylate and (±)-trans-ethyl 2-oxooctahydro-1H-pyrrolo[3,2-c]pyridine-5-carboxylate

artículo científico publicado en 2014

Pseudomonas aeruginosa Quorum Sensing Systems as Drug Discovery Targets: Current Position and Future Perspectives

artículo científico publicado en 2018

Self-Assembling Benzothiazole-Based Gelators: A Mechanistic Understanding of in Vitro Bioactivation and Gelation.

artículo científico publicado en 2018

Synthesis and Evaluation of the First Fluorescent Antagonists of the Human P2Y2 Receptor Based on AR-C118925.

artículo científico publicado en 2018

Synthesis of New DPP-4 Inhibitors Based on a Novel Tricyclic Scaffold

artículo científico publicado en 2015

The Discovery of MMP7 Inhibitors Exploiting a Novel Selectivity Trigger ⬇️

artículo científico publicado el 18 de febrero de 2011

Lista de obras de Michael J Stocks

A practical method for targeted library design balancing lead-like properties with diversity

Antagonists of the P2X(7) receptor. From lead identification to drug development.

Antitumour benzothiazoles. Part 32: DNA adducts and double strand breaks correlate with activity; synthesis of 5F203 hydrogels for local delivery

CXCL17 is an allosteric inhibitor of CXCR4 through a mechanism of action involving glycosaminoglycans

Class 1 PI3K Clinical Candidates and Recent Inhibitor Design Strategies: A Medicinal Chemistry Perspective

Correction to Synthesis and Evaluation of the First Fluorescent Antagonists of the Human P2Y2 Receptor Based on AR-C118925.

Design and Elaboration of a Tractable Tricyclic Scaffold To Synthesize Druglike Inhibitors of Dipeptidyl Peptidase-4 (DPP-4), Antagonists of the C-C Chemokine Receptor Type 5 (CCR5), and Highly Potent and Selective Phosphoinositol-3 Kinase δ (PI3Kδ)

Design driven HtL: The discovery and synthesis of new high efficacy β₂-agonists.

Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists.

Discovery of AZD3199, An Inhaled Ultralong Acting β2 Receptor Agonist with Rapid Onset of Action.

Drug-like Antagonists of P2Y Receptors-From Lead Identification to Drug Development

Efficient and regiospecific one-pot synthesis of substituted 1,2,4-triazoles

From UTP to AR-C118925, the discovery of a potent non nucleotide antagonist of the P2Y2 receptor.

In Silico and in Vitro-Guided Identification of Inhibitors of Alkylquinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa

Ipratropium is 'luminally recycled' by an inter-play between apical uptake and efflux transporters in Calu-3 bronchial epithelial cell layers.

Linifanib--a multi-targeted receptor tyrosine kinase inhibitor and a low molecular weight gelator

Organocatalytic enantioselective one-pot four-component ugi-type multicomponent reaction for the synthesis of epoxy-tetrahydropyrrolo[3,4-b]pyridin-5-ones

Preparation and structural analysis of (±)-cis-ethyl 2-sulfanylidenedecahydro-1,6-naphthyridine-6-carboxylate and (±)-trans-ethyl 2-oxooctahydro-1H-pyrrolo[3,2-c]pyridine-5-carboxylate

Pseudomonas aeruginosa Quorum Sensing Systems as Drug Discovery Targets: Current Position and Future Perspectives

Self-Assembling Benzothiazole-Based Gelators: A Mechanistic Understanding of in Vitro Bioactivation and Gelation.

Synthesis and Evaluation of the First Fluorescent Antagonists of the Human P2Y2 Receptor Based on AR-C118925.

Synthesis of New DPP-4 Inhibitors Based on a Novel Tricyclic Scaffold

The Discovery of MMP7 Inhibitors Exploiting a Novel Selectivity Trigger ⬇️