Lista de obras - Ryo C. Yanagita - Dominio Público Uruguay

A simple analogue of tumor-promoting aplysiatoxin is an antineoplastic agent rather than a tumor promoter: development of a synthetically accessible protein kinase C activator with bryostatin-like activity.

artículo científico publicado en 2009

Binding mode prediction of aplysiatoxin, a potent agonist of protein kinase C, through molecular simulation and structure-activity study on simplified analogs of the receptor-recognition domain

artículo científico publicado en 2016

Challenges to the development of bryostatin-type anticancer drugs based on the activation mechanism of protein kinase Cδ.

artículo científico publicado en 2010

Control of the toxic conformation of amyloid β42 by intramolecular disulfide bond formation

artículo científico publicado en 2020

Design and synthesis of 8-octyl-benzolactam-V9, a selective activator for protein kinase C epsilon and eta.

artículo científico publicado en 2006

Effects of the methoxy group in the side chain of debromoaplysiatoxin on its tumor-promoting and anti-proliferative activities.

artículo científico publicado en 2013

Generation of 'Unnatural Natural Product' library and identification of a small molecule inhibitor of XIAP.

artículo científico publicado en 2011

Identification and biological activities of bryostatins from Japanese bryozoan.

artículo científico publicado en 2012

Indolactam-V is involved in the CH/pi interaction with Pro-11 of the PKCdelta C1B domain: application for the structural optimization of the PKCdelta ligand.

artículo científico publicado en 2005

Loss of the Phenolic Hydroxyl Group and Aromaticity from the Side Chain of Anti-Proliferative 10-Methyl-aplog-1, a Simplified Analog of Aplysiatoxin, Enhances Its Tumor-Promoting and Proinflammatory Activities.

artículo científico publicado en 2017

Practical Enantioselective Reduction of Ketones Using Oxazaborolidine Catalysts Generated In Situ from Chiral Lactam Alcohols

article published in 2018

Role of the phenolic hydroxyl group in the biological activities of simplified analogue of aplysiatoxin with antiproliferative activity ⬇️

artículo científico publicado el 13 de agosto de 2010

Structure-activity studies on the side chain of a simplified analog of aplysiatoxin (aplog-1) with anti-proliferative activity.