Lista de obras - Gabriela da Silva Xavier

5'-AMP-activated protein kinase controls insulin-containing secretory vesicle dynamics

artículo científico publicado en 2003

AMP- and stress-activated protein kinases: key regulators of glucose-dependent gene transcription in mammalian cells?

artículo científico publicado en 2002

ATP depletion inhibits Ca2+ release, influx and extrusion in pancreatic acinar cells but not pathological Ca2+ responses induced by bile

artículo científico publicado en 2007

Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice

artículo científico publicado en 2012

Adipocyte-specific deletion of Tcf7l2 induces dysregulated lipid metabolism and impairs glucose tolerance in mice

artículo científico publicado en 2020

An alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes ⬇️

artículo científico publicado el 14 de septiembre de 2011

Animal models of GWAS-identified type 2 diabetes genes

artículo científico publicado en 2013

Carbohydrate-responsive element-binding protein (ChREBP) is a negative regulator of ARNT/HIF-1beta gene expression in pancreatic islet beta-cells

artículo científico publicado en 2009

Cell type-specific deletion in mice reveals roles for PAS kinase in insulin and glucagon production

artículo científico publicado en 2016

ChREBP binding to fatty acid synthase and L-type pyruvate kinase genes is stimulated by glucose in pancreatic beta-cells

artículo científico publicado en 2006

ChREBP regulates Pdx-1 and other glucose-sensitive genes in pancreatic β-cells

artículo científico publicado en 2010

Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cells

scientific journal article

Convolutional neural networks for reconstruction of undersampled optical projection tomography data applied to in vivo imaging of zebrafish

artículo científico publicado en 2019

Correction: Transcription factor-7-like 2 () gene acts downstream of the kinase to control mTOR signaling, β cell growth, and insulin secretion

artículo científico publicado en 2018

Distinct roles for insulin and insulin-like growth factor-1 receptors in pancreatic beta-cell glucose sensing revealed by RNA silencing

artículo científico publicado en 2004

Divergent effects of liraglutide, exendin-4, and sitagliptin on beta-cell mass and indicators of pancreatitis in a mouse model of hyperglycaemia

artículo científico publicado en 2014

Down-regulation of vascular GLP-1 receptor expression in human subjects with obesity

artículo científico publicado en 2018

Dynamic changes in cytosolic and mitochondrial ATP levels in pancreatic acinar cells

artículo científico publicado en 2010

Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells

artículo científico publicado en 2003

Glucose is necessary for embryonic pancreatic endocrine cell differentiation.

artículo científico publicado en 2007

Glutamine potently stimulates glucagon-like peptide-1 secretion from GLUTag cells.

artículo científico publicado en 2004

Imaging glucose-regulated insulin secretion and gene expression in single islet beta-cells: control by AMP-activated protein kinase

artículo científico publicado en 2004

Importin beta1 mediates the glucose-stimulated nuclear import of pancreatic and duodenal homeobox-1 in pancreatic islet beta-cells (MIN6).

artículo científico publicado en 2004

Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion

artículo científico publicado en 2013

Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants

artículo científico publicado en 2009

Involvement of Per-Arnt-Sim (PAS) kinase in the stimulation of preproinsulin and pancreatic duodenum homeobox 1 gene expression by glucose

artículo científico publicado en 2004

LKB1 and AMPKα1 are required in pancreatic alpha cells for the normal regulation of glucagon secretion and responses to hypoglycemia

artículo científico publicado en 2015

Metabolic and Functional Heterogeneity in Pancreatic β Cells

scientific article published on 13 August 2019

Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion

artículo científico publicado en 2004

Mouse models of peripheral metabolic disease

artículo científico publicado en 2018

Neuronatin regulates pancreatic β cell insulin content and secretion

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells.

artículo científico publicado en 2017

Nucleo-cytosolic shuttling of FoxO1 directly regulates mouse Ins2 but not Ins1 gene expression in pancreatic beta cells (MIN6).

artículo científico publicado en 2011

Pancreatic alpha cell-selective deletion of Tcf7l2 impairs glucagon secretion and counter-regulatory responses to hypoglycaemia in mice.

artículo científico publicado en 2017

Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization

artículo científico publicado en 2010

Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion

scientific journal article

Protein Kinases and Pancreatic Islet Function

article published in 2012

Reduced expression of TCF7L2 in adipocyte impairs glucose tolerance associated with decreased insulin secretion, incretins levels and lipid metabolism dysregulation in male mice

scientific article published on 20 May 2020

Regulation by Per-Arnt-Sim (PAS) kinase of pancreatic duodenal homeobox-1 nuclear import in pancreatic β-cells

scientific article published on 01 November 2006

Regulation of gene expression by glucose in pancreatic beta -cells (MIN6) via insulin secretion and activation of phosphatidylinositol 3'-kinase.

artículo científico publicado en 2000

Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression

artículo científico publicado en 2003

Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis

artículo científico publicado en 2003

Sarco(endo)plasmic reticulum ATPase is a molecular partner of Wolfram syndrome 1 protein, which negatively regulates its expression

artículo científico publicado en 2014

Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass.

artículo científico publicado en 2014

Sodium-potassium ATPase 1 subunit is a molecular partner of Wolframin, an endoplasmic reticulum protein involved in ER stress

artículo científico publicado en 2008

Stimulation of AMP-activated protein kinase is essential for the induction of drug metabolizing enzymes by phenobarbital in human and mouse liver

artículo científico publicado en 2006

Stimulation of acetyl-CoA carboxylase gene expression by glucose requires insulin release and sterol regulatory element binding protein 1c in pancreatic MIN6 beta-cells

artículo científico publicado en 2002

TCF7L2 controls insulin gene expression and insulin secretion in mature pancreatic beta-cells

artículo científico publicado en 2008

TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells

artículo científico publicado en 2009

The Cells of the Islets of Langerhans

artículo científico publicado en 2018

Transcription factor-7-like 2 () gene acts downstream of the / kinase to control mTOR signaling, β cell growth, and insulin secretion

article

miR-29a and miR-29b Contribute to Pancreatic β-Cell-Specific Silencing of Monocarboxylate Transporter 1 (Mct1) ⬇️

artículo científico publicado el 6 de junio de 2011

Lista de obras de Gabriela da Silva Xavier

5'-AMP-activated protein kinase controls insulin-containing secretory vesicle dynamics

AMP- and stress-activated protein kinases: key regulators of glucose-dependent gene transcription in mammalian cells?

ATP depletion inhibits Ca2+ release, influx and extrusion in pancreatic acinar cells but not pathological Ca2+ responses induced by bile

Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice

Adipocyte-specific deletion of Tcf7l2 induces dysregulated lipid metabolism and impairs glucose tolerance in mice

An alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes ⬇️

Animal models of GWAS-identified type 2 diabetes genes

Carbohydrate-responsive element-binding protein (ChREBP) is a negative regulator of ARNT/HIF-1beta gene expression in pancreatic islet beta-cells

Cell type-specific deletion in mice reveals roles for PAS kinase in insulin and glucagon production

ChREBP binding to fatty acid synthase and L-type pyruvate kinase genes is stimulated by glucose in pancreatic beta-cells

ChREBP regulates Pdx-1 and other glucose-sensitive genes in pancreatic β-cells

Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cells

Convolutional neural networks for reconstruction of undersampled optical projection tomography data applied to in vivo imaging of zebrafish

Correction: Transcription factor-7-like 2 () gene acts downstream of the kinase to control mTOR signaling, β cell growth, and insulin secretion

Distinct roles for insulin and insulin-like growth factor-1 receptors in pancreatic beta-cell glucose sensing revealed by RNA silencing

Divergent effects of liraglutide, exendin-4, and sitagliptin on beta-cell mass and indicators of pancreatitis in a mouse model of hyperglycaemia

Down-regulation of vascular GLP-1 receptor expression in human subjects with obesity

Dynamic changes in cytosolic and mitochondrial ATP levels in pancreatic acinar cells

Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells

Glucose is necessary for embryonic pancreatic endocrine cell differentiation.

Glutamine potently stimulates glucagon-like peptide-1 secretion from GLUTag cells.

Imaging glucose-regulated insulin secretion and gene expression in single islet beta-cells: control by AMP-activated protein kinase

Importin beta1 mediates the glucose-stimulated nuclear import of pancreatic and duodenal homeobox-1 in pancreatic islet beta-cells (MIN6).

Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion

Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants

Involvement of Per-Arnt-Sim (PAS) kinase in the stimulation of preproinsulin and pancreatic duodenum homeobox 1 gene expression by glucose

LKB1 and AMPKα1 are required in pancreatic alpha cells for the normal regulation of glucagon secretion and responses to hypoglycemia

Metabolic and Functional Heterogeneity in Pancreatic β Cells

Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion

Mouse models of peripheral metabolic disease

Neuronatin regulates pancreatic β cell insulin content and secretion

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells.

Nucleo-cytosolic shuttling of FoxO1 directly regulates mouse Ins2 but not Ins1 gene expression in pancreatic beta cells (MIN6).

Pancreatic alpha cell-selective deletion of Tcf7l2 impairs glucagon secretion and counter-regulatory responses to hypoglycaemia in mice.

Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization

Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion

Protein Kinases and Pancreatic Islet Function

Reduced expression of TCF7L2 in adipocyte impairs glucose tolerance associated with decreased insulin secretion, incretins levels and lipid metabolism dysregulation in male mice

Regulation by Per-Arnt-Sim (PAS) kinase of pancreatic duodenal homeobox-1 nuclear import in pancreatic β-cells

Regulation of gene expression by glucose in pancreatic beta -cells (MIN6) via insulin secretion and activation of phosphatidylinositol 3'-kinase.

Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression

Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis

Sarco(endo)plasmic reticulum ATPase is a molecular partner of Wolfram syndrome 1 protein, which negatively regulates its expression

Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass.

Sodium-potassium ATPase 1 subunit is a molecular partner of Wolframin, an endoplasmic reticulum protein involved in ER stress

Stimulation of AMP-activated protein kinase is essential for the induction of drug metabolizing enzymes by phenobarbital in human and mouse liver

Stimulation of acetyl-CoA carboxylase gene expression by glucose requires insulin release and sterol regulatory element binding protein 1c in pancreatic MIN6 beta-cells

TCF7L2 controls insulin gene expression and insulin secretion in mature pancreatic beta-cells

TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells

The Cells of the Islets of Langerhans

Transcription factor-7-like 2 () gene acts downstream of the / kinase to control mTOR signaling, β cell growth, and insulin secretion

miR-29a and miR-29b Contribute to Pancreatic β-Cell-Specific Silencing of Monocarboxylate Transporter 1 (Mct1) ⬇️