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Lista de obras de Shanta J. Persaud

A Wake-up Call for Type 2 Diabetes?

artículo científico publicado en 2016

A comparative analysis of human and mouse islet G-protein coupled receptor expression

artículo científico publicado en 2017

A key role for beta-cell cytosolic phospholipase A(2) in the maintenance of insulin stores but not in the initiation of insulin secretion

artículo científico publicado en 2002

A myristoylated pseudosubstrate peptide inhibitor of protein kinase C: effects on glucose- and carbachol-induced insulin secretion

artículo científico publicado en 1996

A novel Gymnema sylvestre extract protects pancreatic beta-cells from cytokine-induced apoptosis

artículo científico publicado en 2019

A novel Gymnema sylvestre extract stimulates insulin secretion from human islets in vivo and in vitro ⬇️

artículo científico publicado el 1 de septiembre de 2010

A novel extract of Gymnema sylvestre improves glucose tolerance in vivo and stimulates insulin secretion and synthesis in vitro.

artículo científico publicado en 2012

A role for islet somatostatin in mediating sympathetic regulation of glucagon secretion

artículo científico publicado en 2010

A role for the extracellular calcium-sensing receptor in cell-cell communication in pancreatic islets of langerhans

artículo científico publicado en 2008

A role for the p42/44 isoforms of MAPK in the regulation of steroid secretion from Y1 mouse adrenocortical cells.

artículo científico publicado en 2000

ACTH stimulates insulin secretion from MIN6 cells and primary mouse and human islets of Langerhans.

artículo científico publicado en 2004

APT070 (mirococept), a membrane-localizing C3 convertase inhibitor, attenuates early human islet allograft damage in vitro and in vivo in a humanized mouse model

artículo científico publicado en 2015

Activation of protein kinase C is essential for sustained insulin secretion in response to cholinergic stimulation

scientific article published on 01 January 1991

Activation of protein kinase C is not required for glyceraldehyde-stimulated insulin secretion from rat islets

artículo científico publicado en 1991

Activation of protein kinase C partially alleviates noradrenaline inhibition of insulin secretion ⬇️

artículo científico publicado el 15 de enero de 1993

Activation of the extracellular calcium-sensing receptor initiates insulin secretion from human islets of Langerhans: involvement of protein kinases

artículo científico publicado en 2006

Adhesion G-protein coupled receptors: Implications for metabolic function

scientific article published on 27 February 2019

All trans-retinoic acid analogs promote cancer cell apoptosis through non-genomic Crabp1 mediating ERK1/2 phosphorylation

artículo científico publicado en 2016

An atlas and functional analysis of G-protein coupled receptors in human islets of Langerhans

artículo científico publicado en 2013

An atlas of G-protein coupled receptor expression and function in human subcutaneous adipose tissue

artículo científico

Analytical electron microscopy of a crack tip extracted from a stressed Alloy 800 sample exposed to an acid sulfate environment

artículo científico publicado en 2014

Annexin A1 Is a Key Modulator of Mesenchymal Stromal Cell-Mediated Improvements in Islet Function

artículo científico publicado en 2015

Anti-apoptotic effects of arachidonic acid and prostaglandin E2 in pancreatic beta-cells.

artículo científico publicado en 2007

Anti-diabetic action of all-trans retinoic acid and the orphan G protein coupled receptor GPRC5C in pancreatic β-cells

artículo científico publicado en 2017

Antidiabetic activity of Croton klozchianus in rats and direct stimulation of insulin secretion in-vitro

artículo científico publicado en 2008

Antisense oligonucleotide inhibition of gene expression: application to endocrine systems.

artículo científico

Arachidonic acid as a second messenger in glucose-induced insulin secretion from pancreatic beta-cells.

artículo científico publicado en 1993

Arachidonic acid induces phosphorylation of an 18 kDa protein in electrically permeabilised rat islets of Langerhans

artículo científico publicado en 1992

Arachidonic acid-induced insulin secretion from rat islets of Langerhans is not mediated by protein phosphorylation

artículo científico publicado en 1993

Assembly of bioactive multilayered nanocoatings on pancreatic islet cells: incorporation of α1-antitrypsin into the coatings

artículo científico publicado en 2015

Assessing Mouse Islet Function

artículo científico publicado en 2020

Atypical isoforms of pKc and insulin secretion from pancreatic beta-cells: evidence using Gö 6976 and Ro 31-8220 as Pkc inhibitors

scientific article published on 01 October 1996

Autocrine anti-apoptotic and proliferative effects of insulin in pancreatic beta-cells

artículo científico publicado en 2006

C3aR and C5aR1 act as key regulators of human and mouse β-cell function.

artículo científico publicado en 2017

CXCL14 Inhibits Insulin Secretion Independently of CXCR4 or CXCR7 Receptor Activation or cAMP Inhibition

artículo científico publicado en 2019

Ca(2+)-induced loss of Ca2+/calmodulin-dependent protein kinase II activity in pancreatic beta-cells

scientific article published on 01 April 1998

Ca2(+)-induced insulin secretion from electrically permeabilized islets. Loss of the Ca2(+)-induced secretory response is accompanied by loss of Ca2(+)-induced protein phosphorylation ⬇️

artículo científico publicado el 1 de agosto de 1992

Calcium/calmodulin-dependent kinase IV controls glucose-induced Irs2 expression in mouse beta cells via activation of cAMP response element-binding protein.

artículo científico publicado en 2011

Can we make a better beta cell?

artículo científico publicado en 2016

Cannabinoid receptor agonists and antagonists stimulate insulin secretion from isolated human islets of Langerhans.

artículo científico publicado en 2011

Cannabinoid receptors are coupled to stimulation of insulin secretion from mouse MIN6 beta-cells

artículo científico publicado en 2010

Cardiac oxidative stress in diabetes: Mechanisms and therapeutic potential

artículo científico publicado en 2016

Catecholamine inhibition of Ca2+-induced insulin secretion from electrically permeabilised islets of Langerhans

scientific article published on 01 July 1987

Cell-based treatments for diabetes

scientific article published on 04 August 2008

Cell-to-cell contact influences proliferative marker expression and apoptosis in MIN6 cells grown in islet-like structures

artículo científico publicado en 2004

Characterisation of the insulinotropic activity of an aqueous extract of Gymnema sylvestre in mouse beta-cells and human islets of Langerhans

artículo científico publicado en 2009

Chronic activation of cannabinoid receptors in vitro does not compromise mouse islet function

artículo científico publicado en 2013

Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cells

scientific journal article

Co-ordinated Ca(2+)-signalling within pancreatic islets: does beta-cell entrainment require a secreted messenger.

artículo científico publicado en 2002

Costus pictus extracts stimulate insulin secretion from mouse and human islets of Langerhans in vitro

artículo científico publicado en 2010

Defining G protein-coupled receptor peptide ligand expressomes and signalomes in human and mouse islets

artículo científico publicado en 2018

Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice.

scientific article published on 08 December 2008

Delta cell secretory responses to insulin secretagogues are not mediated indirectly by insulin.

artículo científico publicado en 2012

Depolarizing stimuli reduce Ca(2+)/calmodulin-dependent protein kinase II activity in islets of Langerhans

scientific article published on 01 April 2000

Diabetes mellitus: a potential target for stem cell therapy

artículo científico publicado en 2006

Differential expression of insulin genes 1 and 2 in MIN6 cells and pseudoislets

artículo científico publicado en 2002

Down-regulation of proliferation does not affect the secretory function of transformed β-cell lines regardless of their anatomical configuration

artículo científico publicado en 2011

Dynamic Profiling of Insulin Secretion and ATP Generation in Isolated Human and Mouse Islets Reveals Differential Glucose Sensitivity

artículo científico publicado en 2017

E-cadherin interactions regulate beta-cell proliferation in islet-like structures

artículo científico publicado en 2007

Editorial overview: Endocrine and metabolic diseases Druggable diabetes: identification of therapeutic opportunities

scientific article published on 13 November 2018

Effect of 17beta-estradiol on insulin secretion and cytosolic calcium in Min6 mouse insulinoma cells and human islets of Langerhans

artículo científico publicado en 2005

Effect of Desmodium gangeticum extract on blood glucose in rats and on insulin secretion in vitro

artículo científico publicado en 2007

Effect of hyperglycaemia on muscarinic M3 receptor expression and secretory sensitivity to cholinergic receptor activation in islets.

artículo científico

Effects of Bordetella pertussis toxin on catecholamine inhibition of insulin release from intact and electrically permeabilized rat islets.

artículo científico publicado en 1989

Effects of a myristoylated pseudosubstrate inhibitor of PKC in intact human platelets

artículo científico publicado en 1995

Effects of myristoylated pseudosubstrate protein kinase C peptide inhibitors on insulin secretion

artículo científico publicado en 1995

Effects of phosphoprotein phosphatase inhibitors on steroidogenesis and StAR protein expression in Y1 cells

scientific article published on 01 August 1998

Electrical permeabilization of rat luteal cells: in situ phosphorylation of endogenous protein.

artículo científico publicado en 1997

Endogenous inhibitors of protein kinase C in pancreatic beta-cells.

artículo científico publicado en 1997

Equilibrative nucleoside transporter 3 depletion in β-cells impairs mitochondrial function and promotes apoptosis: Relationship to pigmented hypertrichotic dermatosis with insulin-dependent diabetes

artículo científico publicado en 2015

Expression and function of cannabinoid receptors in mouse islets

artículo científico publicado en 2010

Expression and function of cyclooxygenase and lipoxygenase enzymes in human islets of Langerhans

artículo científico publicado en 2007

Expression and function of monoacylglycerol lipase in mouse β-cells and human islets of Langerhans

artículo científico publicado en 2012

Expression and function of the extracellular calcium-sensing receptor in pancreatic beta-cells

artículo científico publicado en 2007

Fine tuning of insulin secretion by release of nerve growth factor from mouse and human islet β-cells

artículo científico publicado en 2016

Function and expression of melatonin receptors on human pancreatic islets

artículo científico publicado en 2008

Functional analysis of human islets of Langerhans maintained in culture

artículo científico publicado en 2012

GPR54 peptide agonists stimulate insulin secretion from murine, porcine and human islets

artículo científico publicado en 2011

GPR55-dependent stimulation of insulin secretion from isolated mouse and human islets of Langerhans

artículo científico publicado en 2016

GPR55: from orphan to metabolic regulator?

artículo científico publicado en 2014

Gene expression heterogeneity in human islet endocrine cells in vitro: the insulin signalling cascade.

artículo científico publicado en 2007

Generation of insulin-expressing cells from mouse embryonic stem cells

artículo científico publicado en 2005

Glucose-induced regulation of COX-2 expression in human islets of Langerhans

artículo científico publicado en 2004

Glucose-stimulated insulin secretion from rat islets of Langerhans is independent of mitogen-activated protein kinase activation

scientific article published on 01 October 1997

Glucose-stimulated insulin secretion is not dependent on activation of protein kinase A.

artículo científico publicado en 1990

Gö 6976: an inhibitor of Ca2+/DAG-dependent protein kinase C isoforms in islets of Langerhans

scientific article published on 01 February 1997

Homotypic cell contact enhances insulin but not glucagon secretion

artículo científico publicado en 2006

Human islets derived from donors after cardiac death are fully biofunctional

artículo científico publicado en 2007

Identification of insulin signaling elements in human beta-cells: autocrine regulation of insulin gene expression

artículo científico publicado en 2006

Identifying Signalling Pathways Regulated by GPRC5B in β-Cells by CRISPR-Cas9-Mediated Genome Editing.

artículo científico publicado en 2018

Identifying novel therapeutic targets for diabetes through improved understanding of islet adhesion receptors

scientific article published on 04 August 2018

Imatinib prevents beta cell death in vitro but does not improve islet transplantation outcome.

artículo científico publicado en 2016

Impaired glucose homeostasis and mitochondrial abnormalities in offspring of rats fed a fat-rich diet in pregnancy

artículo científico publicado en 2004

Inhibition of glucose-stimulated insulin secretion by Ro 31-8220, a protein kinase C inhibitor.

artículo científico publicado en 1995

Inhibition of insulin release by staurosporine and Ro 31-8220: a role for protein kinase C?

scientific article published on 01 May 1994

Insulin receptor activation inhibits insulin secretion from human islets of Langerhans

artículo científico publicado en 2002

Insulin secretion and protein phosphorylation in PKC-depleted islets of Langerhans

artículo científico

Insulin secretion from islets of GK rats is not impaired after energy generating steps

artículo científico publicado en 1995

Insulin signalling in islets

artículo científico publicado en 2008

Interdependence of steroidogenesis and shape changes in Y1 adrenocortical cells: studies with inhibitors of phosphoprotein phosphatases.

artículo científico publicado en 2002

Investigation of intracellular signalling cascades mediating stimulatory effect of a Gymnema sylvestre extract on insulin secretion from isolated mouse and human islets of Langerhans ⬇️

artículo científico publicado el 1 de agosto de 2012

Islet G-protein coupled receptors: therapeutic potential for diabetes

artículo científico publicado en 2017

Islet alpha-cells do not influence insulin secretion from beta-cells through cell-cell contact

artículo científico publicado en 2007

Islet neogenesis-associated protein signaling in neonatal pancreatic rat islets: involvement of the cholinergic pathway.

artículo científico publicado en 2008

Islet neuropeptide Y receptors are functionally conserved and novel targets for the preservation of beta-cell mass

artículo científico publicado en 2017

Kisspeptin stimulation of insulin secretion: mechanisms of action in mouse islets and rats.

artículo científico publicado en 2009

LH-21 and abnormal cannabidiol improve β-cell function in isolated human and mouse islets through GPR55-dependent and -independent signalling

artículo científico publicado en 2017

Low levels of glucose transporters and K+ATP channels in human pancreatic beta cells early in development.

artículo científico publicado en 2007

MIN6 beta-cell-beta-cell interactions influence insulin secretory responses to nutrients and non-nutrients.

artículo científico publicado en 2006

Mastoparan stimulates insulin secretion from pancreatic beta-cells by effects at a late stage in the secretory pathway

artículo científico publicado en 1993

Mesenchymal stromal cell secretory factors induce sustained improvements in islet function pre- and post-transplantation

artículo científico publicado en 2018

Metabolic phenotyping guidelines: assessing glucose homeostasis in rodent models

artículo científico publicado en 2014

Nitric oxide is not involved in the initiation of insulin secretion from rat islets of Langerhans

artículo científico publicado en 1992

Nupr1 deletion protects against glucose intolerance by increasing beta cell mass

artículo científico publicado en 2013

Pancreatic beta-cell-to-beta-cell interactions are required for integrated responses to nutrient stimuli: enhanced Ca2+ and insulin secretory responses of MIN6 pseudoislets.

artículo científico publicado en 1999

Pancreatic deletion of insulin receptor substrate 2 reduces beta and alpha cell mass and impairs glucose homeostasis in mice

artículo científico publicado en 2007

Pancreatic duodenal homeobox 1 expression is insufficient to transdifferentiate liver cells into insulin-secreting cells

artículo científico publicado en 2007

Peptide YY: more than just an appetite regulator

artículo científico publicado en 2014

Phosphoprotein phosphatase activities in rat luteal cells

artículo científico publicado en 1995

Phosphoprotein phosphatases regulate steroidogenesis by influencing StAR gene transcription.

artículo científico publicado en 2000

Prolonged activation of human islet cannabinoid receptors in vitro induces adaptation but not dysfunction

artículo científico publicado en 2016

Prostaglandin F2 alpha activates protein kinase C in human ovarian cells

scientific article published on 01 February 1993

Protein Kinase C Signalling in Pancreatic Beta-Cells: Cellular and Molecular Approaches ⬇️

artículo científico publicado el 1 de enero de 1997

Protein kinase C and the regulation of insulin secretion.

artículo científico publicado en 1990

Protein kinases, protein phosphorylation, and the regulation of insulin secretion from pancreatic beta-cells

artículo científico publicado en 1998

Pseudoislets as primary islet replacements for research: report on a symposium at King's College London, London UK.

artículo científico publicado en 2010

Pseudosubstrate inhibition of cyclic AMP-dependent protein kinase in intact pancreatic islets: effects on cyclic AMP-dependent and glucose-dependent insulin secretion

artículo científico publicado en 1997

Reduced nuclear protein 1 expression improves insulin sensitivity and protects against diet-induced glucose intolerance through up-regulation of heat shock protein 70.

artículo científico publicado en 2015

Regulation of insulin secretion: the role of second messengers.

artículo científico publicado en 1994

Requirement of NF-kappaB signalling pathway for modulation of the cholinergic muscarinic M3 receptor expression by INGAP-PP in insulin-producing cells.

artículo científico publicado en 2010

Retinoic Acid Induces Ubiquitination-Resistant RIP140/LSD1 Complex to Fine-Tune Pax6 Gene in Neuronal Differentiation

artículo científico publicado en 2015

Role of phosphoprotein phosphatases in the corpus luteum: I identification and characterisation of serine/threonine phosphoprotein phosphatases in isolated rat luteal cells

artículo científico publicado en 1996

Role of phosphoprotein phosphatases in the corpus luteum: II control of progesterone secretion by isolated rat luteal cells

artículo científico publicado en 1996

Role of the endocannabinoid system in food intake, energy homeostasis and regulation of the endocrine pancreas

artículo científico publicado en 2010

Selective ablation of peptide YY cells in adult mice reveals their role in beta cell survival

artículo científico publicado en 2012

Short chain fatty acids stimulate insulin secretion and reduce apoptosis in mouse and human islets in vitro: Role of free fatty acid receptor 2

artículo científico publicado en 2018

Signaling through the p38 and p42/44 mitogen-activated families of protein kinases in pancreatic beta-cell proliferation.

artículo científico publicado en 2000

Similarities of K+ATP channel expression and Ca2+ changes in pancreatic beta cells and hypothalamic neurons

artículo científico publicado en 2005

Single-cell RT-PCR identification of genes expressed by human islet endocrine cells.

artículo científico publicado en 2009

Somatostatin secreted by islet delta-cells fulfills multiple roles as a paracrine regulator of islet function

artículo científico publicado en 2008

Staurosporine inhibits protein kinases activated by Ca2+ and cyclic AMP in addition to inhibiting protein kinase C in rat islets of Langerhans

artículo científico publicado en 1993

Stem cell therapy for diabetes: do we need to make beta cells?

artículo científico publicado en 2004

Stem cells and the endocrine pancreas

scientific article published on 03 June 2011

Synchronization of Ca(2+)-signals within insulin-secreting pseudoislets: effects of gap-junctional uncouplers.

artículo científico publicado en 2000

The Association Between Selective Serotonin Reuptake Inhibitors and Glycemia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

scientific article published on 01 September 2019

The CaMK4/CREB/IRS-2 Cascade Stimulates Proliferation and Inhibits Apoptosis of β-Cells ⬇️

artículo científico publicado el 25 de septiembre de 2012

The Placental Secretome: Identifying Potential Cross-Talk Between Placenta and Islet β-Cells

artículo científico publicado en 2018

The adhesion receptor GPR56 is activated by extracellular matrix collagen III to improve β-cell function

artículo científico publicado en 2018

The cannabinoid ligand LH-21 reduces anxiety and improves glucose handling in diet-induced obese pre-diabetic mice.

artículo científico publicado en 2017

The cannabinoid ligands SR141716A and AM251 enhance human and mouse islet function via GPR55-independent signalling

artículo científico publicado en 2020

The development of new density gradient media for purifying human islets and islet-quality assessments

artículo científico publicado en 2004

The diet-derived short chain fatty acid propionate improves beta-cell function in humans and stimulates insulin secretion from human islets in vitro

artículo científico publicado en 2016

The extracellular calcium-sensing receptor in PHHI beta cells: does reduced auto-inhibitory input contribute to hypersecretion of insulin?

artículo científico publicado en 2000

The in vitro differentiation of rat neural stem cells into an insulin-expressing phenotype

artículo científico publicado en 2005

The inhibition of stimulus-secretion coupling in pancreatic islets by volatile anaesthetics does not involve pertussis toxin sensitive G-proteins

artículo científico publicado en 1994

The involvement of protein kinase C in glucose-stimulated insulin secretion

scientific article published on 01 November 1993

The mitogen-activated protein kinase cascade in rat islets of Langerhans

scientific article published on 01 May 1995

The mitogen-activated protein kinase pathway in rat islets of Langerhans: studies on the regulation of insulin secretion

artículo científico publicado en 1996

The monounsaturated fatty acid oleate is the major physiological toxic free fatty acid for human beta cells.

artículo científico publicado en 2017

The novel chemokine receptor, G-protein-coupled receptor 75, is expressed by islets and is coupled to stimulation of insulin secretion and improved glucose homeostasis

artículo científico publicado en 2013

The permissive effects of glucose on receptor-operated potentiation of insulin secretion from mouse islets: a role for ERK1/2 activation and cytoskeletal remodelling.

artículo científico publicado en 2013

The role of arachidonic acid and its metabolites in insulin secretion from human islets of langerhans

artículo científico publicado en 2007

The role of cytosolic phospholipase A(2) in insulin secretion

artículo científico publicado en 2004

The role of protein kinase C in insulin biosynthesis.

artículo científico publicado en 1993

Time-course of Ca2+-induced insulin secretion from perifused, electrically permeabilised islets of Langerhans: effects of cAMP and a phorbol ester

artículo científico publicado en 1989

Translocation of protein kinase C in rat islets of Langerhans. Effects of a phorbol ester, carbachol and glucose

artículo científico publicado en 1989

Tyrosine kinase inhibitors inhibit glucose-stimulated insulin secretion

scientific article published on 01 May 1994

Tyrosine kinases play a permissive role in glucose-induced insulin secretion from adult rat islets.

artículo científico publicado en 1999

Uncoupling of nutrient metabolism from insulin secretion by overexpression of cytosolic phospholipase A(2).

artículo científico publicado en 2005

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