Lista de obras - Junyan Lu - Dominio Público Uruguay

A computational investigation on the substrate preference of ten-eleven-translocation 2 (TET2).

artículo científico publicado en 2016

A gating mechanism for Pi release governs the mRNA unwinding by eIF4AI during translation initiation

artículo científico publicado en 2015

A quantum mechanics/molecular mechanics study on the hydrolysis mechanism of New Delhi metallo-β-lactamase-1.

artículo científico publicado en 2013

Application of Epigenome‐Modifying Small Molecules in Induced Pluripotent Stem Cells ⬇️

artículo científico publicado el 11 de mayo de 2012

Astemizole arrests the proliferation of cancer cells by disrupting the EZH2-EED interaction of polycomb repressive complex 2.

artículo científico publicado en 2014

CXCR4 hyperactivation cooperates with TCL1 in CLL development and aggressiveness

artículo científico publicado en 2021

Catalytic mechanism investigation of lysine-specific demethylase 1 (LSD1): a computational study

artículo científico publicado en 2011

Catalytic mechanism of histone acetyltransferase p300: from the proton transfer to acetylation reaction

artículo científico publicado en 2014

Developmental subtypes assessed by DNA methylation-iPLEX forecast the natural history of chronic lymphocytic leukemia

artículo científico publicado en 2019

Drug-perturbation-based stratification of blood cancer

artículo científico publicado en 2017

Energy metabolism is co-determined by genetic variants in chronic lymphocytic leukemia and influences drug sensitivity

artículo científico publicado en 2019

FTY720 induces apoptosis of M2 subtype acute myeloid leukemia cells by targeting sphingolipid metabolism and increasing endogenous ceramide levels

artículo científico publicado en 2014

Helix Unfolding/Refolding Characterizes the Functional Dynamics of Staphylococcus aureus Clp Protease ⬇️

artículo científico publicado el 26 de abril de 2013

IGLV3-21R110 identifies an aggressive biological subtype of chronic lymphocytic leukemia with intermediate epigenetics

artículo científico publicado en 2020

Inferring tumor-specific cancer dependencies through integrating ex vivo drug response assays and drug-protein profiling

artículo científico publicado en 2022

Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A.

artículo científico publicado en 2017

Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation

artículo científico publicado en 2015

Investigation of the Acetylation Mechanism by GCN5 Histone Acetyltransferase ⬇️

artículo científico publicado el 4 de mayo de 2012

MDM4 Is Targeted by 1q Gain and Drives Disease in Burkitt Lymphoma

scientific article published on 18 April 2019

Molecular-dynamics-simulation-driven design of a protease-responsive probe for in-vivo tumor imaging

artículo científico publicado en 2014

Multi-omics reveals clinically relevant proliferative drive associated with mTOR-MYC-OXPHOS activity in chronic lymphocytic leukemia

artículo científico publicado en 2021

Network modelling reveals the mechanism underlying colitis-associated colon cancer and identifies novel combinatorial anti-cancer targets

artículo científico publicado en 2015

Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer

artículo científico publicado en 2020

Structural insight into substrate preference for TET-mediated oxidation

artículo científico publicado en 2015

Structure-based computational study of the hydrolysis of New Delhi metallo-β-lactmase-1.

artículo científico publicado en 2013

TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma

artículo científico publicado en 2018

Targeting the N Terminus of eIF4AI for Inhibition of Its Catalytic Recycling

scientific article published on 08 August 2019

The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome

artículo científico publicado en 2020

Theoretical insights into catalytic mechanism of protein arginine methyltransferase 1

artículo científico publicado en 2013

Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA ⬇️

artículo científico publicado el 12 de febrero de 2012

Lista de obras de Junyan Lu

A computational investigation on the substrate preference of ten-eleven-translocation 2 (TET2).

A gating mechanism for Pi release governs the mRNA unwinding by eIF4AI during translation initiation

A quantum mechanics/molecular mechanics study on the hydrolysis mechanism of New Delhi metallo-β-lactamase-1.

Application of Epigenome‐Modifying Small Molecules in Induced Pluripotent Stem Cells ⬇️

Astemizole arrests the proliferation of cancer cells by disrupting the EZH2-EED interaction of polycomb repressive complex 2.

CXCR4 hyperactivation cooperates with TCL1 in CLL development and aggressiveness

Catalytic mechanism investigation of lysine-specific demethylase 1 (LSD1): a computational study

Catalytic mechanism of histone acetyltransferase p300: from the proton transfer to acetylation reaction

Developmental subtypes assessed by DNA methylation-iPLEX forecast the natural history of chronic lymphocytic leukemia

Drug-perturbation-based stratification of blood cancer

Energy metabolism is co-determined by genetic variants in chronic lymphocytic leukemia and influences drug sensitivity

FTY720 induces apoptosis of M2 subtype acute myeloid leukemia cells by targeting sphingolipid metabolism and increasing endogenous ceramide levels

Helix Unfolding/Refolding Characterizes the Functional Dynamics of Staphylococcus aureus Clp Protease ⬇️

IGLV3-21R110 identifies an aggressive biological subtype of chronic lymphocytic leukemia with intermediate epigenetics

Inferring tumor-specific cancer dependencies through integrating ex vivo drug response assays and drug-protein profiling

Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A.

Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation

Investigation of the Acetylation Mechanism by GCN5 Histone Acetyltransferase ⬇️

MDM4 Is Targeted by 1q Gain and Drives Disease in Burkitt Lymphoma

Molecular-dynamics-simulation-driven design of a protease-responsive probe for in-vivo tumor imaging

Multi-omics reveals clinically relevant proliferative drive associated with mTOR-MYC-OXPHOS activity in chronic lymphocytic leukemia

Network modelling reveals the mechanism underlying colitis-associated colon cancer and identifies novel combinatorial anti-cancer targets

Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer

Structural insight into substrate preference for TET-mediated oxidation

Structure-based computational study of the hydrolysis of New Delhi metallo-β-lactmase-1.

TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma

Targeting the N Terminus of eIF4AI for Inhibition of Its Catalytic Recycling

The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome

Theoretical insights into catalytic mechanism of protein arginine methyltransferase 1

Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA ⬇️