Lista de obras - Franck Tirode - Dominio Público Uruguay

A Role for the TFIIH XPB DNA Helicase in Promoter Escape by RNA Polymerase II

artículo científico publicado en 1999

A conditionally expressed third partner stabilizes or prevents the formation of a transcriptional activator in a three-hybrid system

artículo científico publicado en 1997

A functional, new short isoform of death receptor 4 in Ewing's sarcoma cell lines may be involved in TRAIL sensitivity/resistance mechanisms

artículo científico publicado en 2012

A new subtype of bone sarcoma defined by BCOR-CCNB3 gene fusion

artículo científico publicado en 2012

A subset of epithelioid and spindle cell rhabdomyosarcomas is associated with TFCP2 fusions and common ALK upregulation

artículo científico publicado en 2019

Abnormal vascularization of soft-tissue sarcomas on conventional MRI: Diagnostic and prognostic values

artículo científico publicado en 2019

Alternative PDGFD rearrangements in dermatofibrosarcomas protuberans without PDGFB fusions

scientific article published on 28 June 2018

Antagonism pattern detection between microRNA and target expression in Ewing's sarcoma

artículo científico publicado en 2012

Attempting to Solve the Pigmented Epithelioid Melanocytoma (PEM) Conundrum

artículo científico publicado en 2022

BAFfling pathologies: Alterations of BAF complexes in cancer.

artículo científico publicado en 2018

Bone sarcomas: from biology to targeted therapies.

artículo científico publicado en 2012

Brain tumor with an ATXN1-NUTM1 fusion gene expands the histologic spectrum of NUTM1-rearranged neoplasia

scientific article published on 30 December 2019

CIC-DUX4 expression drives the development of small round cell sarcoma in transgenic zebrafish: a new model revealing a role for ETV4 in CIC-mediated sarcomagenesis

article

CRTC1-TRIM11 fusion defined melanocytic tumors: A series of four cases

scientific article published on 09 July 2019

CYSLTR2-mutant Cutaneous Melanocytic Neoplasms Frequently Simulate "Pigmented Epithelioid Melanocytoma," Expanding the Morphologic Spectrum of Blue Tumors: A Clinicopathologic Study of 7 Cases

artículo científico publicado en 2019

Cancer-associated SF3B1 mutations affect alternative splicing by promoting alternative branchpoint usage

artículo científico publicado en 2016

Cellular origin of Ewing's tumor. A corner of the veil is lifted

artículo científico publicado en 2008

Chimeric EWSR1-FLI1 regulates the Ewing sarcoma susceptibility gene EGR2 via a GGAA microsatellite

artículo científico publicado en 2015

Clear Cell Tumor With Melanocytic Differentiation and ACTIN-MITF Translocation: Report of 7 Cases of a Novel Entity

scientific article published on 01 December 2020

Clinicopathologic Features of CIC-NUTM1 Sarcomas, a New Molecular Variant of the Family of CIC-fused Sarcomas

artículo científico publicado en 2019

Clinicopathologic and Molecular Features of a Series of 41 Biphenotypic Sinonasal Sarcomas Expanding Their Molecular Spectrum

artículo científico publicado en 2019

Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model

artículo científico publicado en 2016

Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma

artículo científico publicado en 2012

Complete response to CSF1R inhibitor in a translocation variant of teno-synovial giant cell tumor without genomic alteration of the CSF1 gene

article

Comprehensive molecular and pathological evaluation of transitional mesothelioma assisted by deep learning approach: a multi institutional study of the International Mesothelioma Panel from MESOPATH Reference Center

scientific article published on 09 March 2020

Correction: NFATc2-rearranged sarcomas: clinicopathologic, molecular, and cytogenetic study of 7 cases with evidence of AGGRECAN as a novel diagnostic marker

artículo científico publicado en 2020

Cutaneous Melanocytic Tumors With Concomitant NRASQ61R and IDH1R132C Mutations: A Report of 6 Cases

scientific article published on 23 July 2020

De novo motif identification improves the accuracy of predicting transcription factor binding sites in ChIP-Seq data analysis.

artículo científico publicado en 2010

Development of curative therapies for Ewing sarcomas by interdisciplinary cooperative groups in Europe

artículo científico publicado en 2015

ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in the EWS-FLI1 oncogenic fusion

artículo científico publicado en 2021

ETV4 is a useful marker for the diagnosis of CIC-rearranged undifferentiated round-cell sarcomas: a study of 127 cases including mimicking lesions

artículo científico publicado en 2016

EURACAN/IASLC Proposals for Updating the Histologic Classification of Pleural Mesothelioma: Towards a More Multidisciplinary Approach

scientific article published on 20 September 2019

EWS-FLI1 inhibits TNFalpha-induced NFkappaB-dependent transcription in Ewing sarcoma cells

artículo científico publicado en 2010

EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3.

artículo científico publicado en 2004

Fusion partners of NTRK3 affect subcellular localization of the fusion kinase and cytomorphology of melanocytes

scientific article published on 23 September 2020

Genetic analyses of undifferentiated small round cell sarcoma identifies a novel sarcoma subtype with a recurrent CRTC1-SS18 gene fusion.

artículo científico publicado en 2018

Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility

scientific article published in Nature Communications

Genomic and transcriptomic characterisation of undifferentiated pleomorphic sarcoma of bone

artículo científico publicado en 2018

Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations

artículo científico publicado en 2014

Integrative clinical and biopathology analyses to understand the clinical heterogeneity of infantile rhabdomyosarcoma: A report from the French MMT committee

artículo científico publicado en 2020

Intra- and extra-cranial BCOR-ITD tumours are separate entities within the BCOR-rearranged family

artículo científico publicado en 2022

Loss of connexin43 expression in Ewing's sarcoma cells favors the development of the primary tumor and the associated bone osteolysis.

artículo científico publicado en 2013

Low-frequency variation near common germline susceptibility loci are associated with risk of Ewing sarcoma

artículo científico publicado en 2020

Malignant melanoma with areas of rhabdomyosarcomatous differentiation arising in a giant congenital nevus with RAF1 gene fusion

scientific article published on 21 April 2019

Melanocytic tumors with MAP3K8 fusions: report of 33 cases with morphological-genetic correlations

scientific article published on 12 November 2019

Mesenchymal stem cell features of Ewing tumors

artículo científico publicado en 2007

Molecular Classification of Endometrial Stromal Sarcomas Using RNA Sequencing Defines Nosological and Prognostic Subgroups with Different Natural History

scientific article published on 11 September 2020

NFATc2-rearranged sarcomas: clinicopathologic, molecular, and cytogenetic study of 7 cases with evidence of AGGRECAN as a novel diagnostic marker

scientific article published on 23 April 2020

Neonatal Soft Tissue Sarcoma with YWHAE-NUTM2B Fusion

artículo científico publicado en 2019

Novel three-way complex rearrangement of TRPM1-PUM1-LCK in a case of agminated Spitz nevi arising in a giant congenital hyperpigmented macule

artículo científico publicado en 2020

Oncostatin M is a growth factor for Ewing sarcoma

artículo científico publicado en 2012

Osteoprotegerin inhibits bone resorption and prevents tumor development in a xenogenic model of Ewing's sarcoma by inhibiting RANKL

artículo científico publicado en 2013

PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis.

artículo científico publicado en 2018

Preclinical evidence that use of TRAIL in Ewing's sarcoma and osteosarcoma therapy inhibits tumor growth, prevents osteolysis, and increases animal survival

artículo científico publicado en 2010

Reconstitution of the transcription factor TFIIH: assignment of functions for the three enzymatic subunits, XPB, XPD, and cdk7

scientific journal article

Recurrent novel THBS1-ADGRF5 gene fusion in a new tumor subtype "Acral FibroChondroMyxoid Tumors"

scientific article published on 11 February 2020

SMARCA4 inactivation defines a group of undifferentiated thoracic malignancies transcriptionally related to BAF-deficient sarcomas

artículo científico publicado en 2015

SMARCA4-deficient Thoracic Sarcomas: Clinicopathologic Study of 30 Cases With an Emphasis on Their Nosology and Differential Diagnoses

artículo científico publicado en 2019

SRF Fusions Other Than With RELA Expand the Molecular Definition of SRF-fused Perivascular Tumors

artículo científico publicado en 2020

SRF-FOXO1 and SRF-NCOA1 Fusion Genes Delineate a Distinctive Subset of Well-differentiated Rhabdomyosarcoma

artículo científico publicado en 2020

Stem cells and connective-tissue tumors: Ewing's sarcoma

artículo científico publicado en 2008

Strong smooth muscle differentiation is dependent on myocardin gene amplification in most human retroperitoneal leiomyosarcomas.

artículo científico publicado en 2009

Systems biology of Ewing sarcoma: a network model of EWS-FLI1 effect on proliferation and apoptosis

artículo científico publicado en 2013

Targeting the EWSR1-FLI1 oncogene-induced protein kinase PKC-β abolishes ewing sarcoma growth

artículo científico publicado en 2012

Targeting the epigenetic readers in Ewing sarcoma inhibits the oncogenic transcription factor EWS/Fli1.

artículo científico publicado en 2016

The ENCCA-WP7/EuroSarc/EEC/PROVABES/EURAMOS 3rd European Bone Sarcoma Networking Meeting/Joint Workshop of EU Bone Sarcoma Translational Research Networks; Vienna, Austria, September 24-25, 2015. Workshop Report

artículo científico publicado en 2016

The first European interdisciplinary ewing sarcoma research summit ⬇️

artículo científico publicado en 2012

The oncogenic EWS-FLI1 protein binds in vivo GGAA microsatellite sequences with potential transcriptional activation function

artículo científico publicado en 2009

The orphan nuclear receptor DAX1 is up-regulated by the EWS/FLI1 oncoprotein and is highly expressed in Ewing tumors

artículo científico publicado en 2006

The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease

artículo científico publicado en 2016

Therapeutic Targeting of KDM1A/LSD1 in Ewing Sarcoma with SP-2509 Engages the Endoplasmic Reticulum Stress Response

artículo científico publicado en 2018

Tocilizumab for the treatment of paraneoplastic inflammatory syndrome associated with angiomatoid fibrous histiocytoma

artículo científico publicado en 2020

Transcriptional Programs Define Intratumoral Heterogeneity of Ewing Sarcoma at Single-Cell Resolution

artículo científico publicado en 2020

Transcriptomic definition of molecular subgroups of small round cell sarcomas.

artículo científico publicado en 2018

Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis

artículo científico publicado en 2015

Update on Families of Round Cell Sarcomas Other than Classical Ewing Sarcomas.

artículo científico

Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity

artículo científico publicado en 2010

Very long-term survivors among patients with metastatic soft tissue sarcoma

artículo científico publicado en 2019

Zoledronic acid as a new adjuvant therapeutic strategy for Ewing's sarcoma patients

artículo científico publicado en 2010

deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish

artículo científico publicado en 2018

Lista de obras de Franck Tirode

A Role for the TFIIH XPB DNA Helicase in Promoter Escape by RNA Polymerase II

A conditionally expressed third partner stabilizes or prevents the formation of a transcriptional activator in a three-hybrid system

A functional, new short isoform of death receptor 4 in Ewing's sarcoma cell lines may be involved in TRAIL sensitivity/resistance mechanisms

A new subtype of bone sarcoma defined by BCOR-CCNB3 gene fusion

A subset of epithelioid and spindle cell rhabdomyosarcomas is associated with TFCP2 fusions and common ALK upregulation

Abnormal vascularization of soft-tissue sarcomas on conventional MRI: Diagnostic and prognostic values

Alternative PDGFD rearrangements in dermatofibrosarcomas protuberans without PDGFB fusions

Antagonism pattern detection between microRNA and target expression in Ewing's sarcoma

Attempting to Solve the Pigmented Epithelioid Melanocytoma (PEM) Conundrum

BAFfling pathologies: Alterations of BAF complexes in cancer.

Bone sarcomas: from biology to targeted therapies.

Brain tumor with an ATXN1-NUTM1 fusion gene expands the histologic spectrum of NUTM1-rearranged neoplasia

CIC-DUX4 expression drives the development of small round cell sarcoma in transgenic zebrafish: a new model revealing a role for ETV4 in CIC-mediated sarcomagenesis

CRTC1-TRIM11 fusion defined melanocytic tumors: A series of four cases

CYSLTR2-mutant Cutaneous Melanocytic Neoplasms Frequently Simulate "Pigmented Epithelioid Melanocytoma," Expanding the Morphologic Spectrum of Blue Tumors: A Clinicopathologic Study of 7 Cases

Cancer-associated SF3B1 mutations affect alternative splicing by promoting alternative branchpoint usage

Cellular origin of Ewing's tumor. A corner of the veil is lifted

Chimeric EWSR1-FLI1 regulates the Ewing sarcoma susceptibility gene EGR2 via a GGAA microsatellite

Clear Cell Tumor With Melanocytic Differentiation and ACTIN-MITF Translocation: Report of 7 Cases of a Novel Entity

Clinicopathologic Features of CIC-NUTM1 Sarcomas, a New Molecular Variant of the Family of CIC-fused Sarcomas

Clinicopathologic and Molecular Features of a Series of 41 Biphenotypic Sinonasal Sarcomas Expanding Their Molecular Spectrum

Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model

Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma

Complete response to CSF1R inhibitor in a translocation variant of teno-synovial giant cell tumor without genomic alteration of the CSF1 gene

Comprehensive molecular and pathological evaluation of transitional mesothelioma assisted by deep learning approach: a multi institutional study of the International Mesothelioma Panel from MESOPATH Reference Center

Correction: NFATc2-rearranged sarcomas: clinicopathologic, molecular, and cytogenetic study of 7 cases with evidence of AGGRECAN as a novel diagnostic marker

Cutaneous Melanocytic Tumors With Concomitant NRASQ61R and IDH1R132C Mutations: A Report of 6 Cases

De novo motif identification improves the accuracy of predicting transcription factor binding sites in ChIP-Seq data analysis.

Development of curative therapies for Ewing sarcomas by interdisciplinary cooperative groups in Europe

ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in the EWS-FLI1 oncogenic fusion

ETV4 is a useful marker for the diagnosis of CIC-rearranged undifferentiated round-cell sarcomas: a study of 127 cases including mimicking lesions

EURACAN/IASLC Proposals for Updating the Histologic Classification of Pleural Mesothelioma: Towards a More Multidisciplinary Approach

EWS-FLI1 inhibits TNFalpha-induced NFkappaB-dependent transcription in Ewing sarcoma cells

EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3.

Fusion partners of NTRK3 affect subcellular localization of the fusion kinase and cytomorphology of melanocytes

Genetic analyses of undifferentiated small round cell sarcoma identifies a novel sarcoma subtype with a recurrent CRTC1-SS18 gene fusion.

Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility

Genomic and transcriptomic characterisation of undifferentiated pleomorphic sarcoma of bone

Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations

Integrative clinical and biopathology analyses to understand the clinical heterogeneity of infantile rhabdomyosarcoma: A report from the French MMT committee

Intra- and extra-cranial BCOR-ITD tumours are separate entities within the BCOR-rearranged family

Loss of connexin43 expression in Ewing's sarcoma cells favors the development of the primary tumor and the associated bone osteolysis.

Low-frequency variation near common germline susceptibility loci are associated with risk of Ewing sarcoma

Malignant melanoma with areas of rhabdomyosarcomatous differentiation arising in a giant congenital nevus with RAF1 gene fusion

Melanocytic tumors with MAP3K8 fusions: report of 33 cases with morphological-genetic correlations

Mesenchymal stem cell features of Ewing tumors

Molecular Classification of Endometrial Stromal Sarcomas Using RNA Sequencing Defines Nosological and Prognostic Subgroups with Different Natural History

NFATc2-rearranged sarcomas: clinicopathologic, molecular, and cytogenetic study of 7 cases with evidence of AGGRECAN as a novel diagnostic marker

Neonatal Soft Tissue Sarcoma with YWHAE-NUTM2B Fusion

Novel three-way complex rearrangement of TRPM1-PUM1-LCK in a case of agminated Spitz nevi arising in a giant congenital hyperpigmented macule

Oncostatin M is a growth factor for Ewing sarcoma

Osteoprotegerin inhibits bone resorption and prevents tumor development in a xenogenic model of Ewing's sarcoma by inhibiting RANKL

PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis.

Preclinical evidence that use of TRAIL in Ewing's sarcoma and osteosarcoma therapy inhibits tumor growth, prevents osteolysis, and increases animal survival

Reconstitution of the transcription factor TFIIH: assignment of functions for the three enzymatic subunits, XPB, XPD, and cdk7

Recurrent novel THBS1-ADGRF5 gene fusion in a new tumor subtype "Acral FibroChondroMyxoid Tumors"

SMARCA4 inactivation defines a group of undifferentiated thoracic malignancies transcriptionally related to BAF-deficient sarcomas

SMARCA4-deficient Thoracic Sarcomas: Clinicopathologic Study of 30 Cases With an Emphasis on Their Nosology and Differential Diagnoses

SRF Fusions Other Than With RELA Expand the Molecular Definition of SRF-fused Perivascular Tumors

SRF-FOXO1 and SRF-NCOA1 Fusion Genes Delineate a Distinctive Subset of Well-differentiated Rhabdomyosarcoma

Stem cells and connective-tissue tumors: Ewing's sarcoma

Strong smooth muscle differentiation is dependent on myocardin gene amplification in most human retroperitoneal leiomyosarcomas.

Systems biology of Ewing sarcoma: a network model of EWS-FLI1 effect on proliferation and apoptosis

Targeting the EWSR1-FLI1 oncogene-induced protein kinase PKC-β abolishes ewing sarcoma growth

Targeting the epigenetic readers in Ewing sarcoma inhibits the oncogenic transcription factor EWS/Fli1.

The ENCCA-WP7/EuroSarc/EEC/PROVABES/EURAMOS 3rd European Bone Sarcoma Networking Meeting/Joint Workshop of EU Bone Sarcoma Translational Research Networks; Vienna, Austria, September 24-25, 2015. Workshop Report

The first European interdisciplinary ewing sarcoma research summit ⬇️

The oncogenic EWS-FLI1 protein binds in vivo GGAA microsatellite sequences with potential transcriptional activation function

The orphan nuclear receptor DAX1 is up-regulated by the EWS/FLI1 oncoprotein and is highly expressed in Ewing tumors

The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease

Therapeutic Targeting of KDM1A/LSD1 in Ewing Sarcoma with SP-2509 Engages the Endoplasmic Reticulum Stress Response

Tocilizumab for the treatment of paraneoplastic inflammatory syndrome associated with angiomatoid fibrous histiocytoma

Transcriptional Programs Define Intratumoral Heterogeneity of Ewing Sarcoma at Single-Cell Resolution

Transcriptomic definition of molecular subgroups of small round cell sarcomas.

Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis

Update on Families of Round Cell Sarcomas Other than Classical Ewing Sarcomas.

Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity

Very long-term survivors among patients with metastatic soft tissue sarcoma

Zoledronic acid as a new adjuvant therapeutic strategy for Ewing's sarcoma patients

Malignant melanoma with areas of rhabdomyosarcomatous differentiation arising in a giant congenital nevus with RAF1 gene fusion