Lista de obras - Carsten Hopf - Dominio Público Uruguay

4-Phenyl-α-cyanocinnamic acid amide: screening for a negative ion matrix for MALDI-MS imaging of multiple lipid classes.

artículo científico publicado en 2013

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

artículo científico publicado en 2004

A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiation

artículo científico publicado en 2012

Affinity profiling of the cellular kinome for the nucleotide cofactors ATP, ADP, and GTP.

artículo científico publicado en 2013

Altered mitochondrial and peroxisomal integrity in lipocalin-2-deficient mice with hepatic steatosis

artículo científico publicado en 2017

Alzheimer's-Causing Mutations Shift Aβ Length by Destabilizing γ-Secretase-Aβn Interactions

artículo científico publicado en 2017

Calcium-dependent maintenance of agrin-induced postsynaptic specializations.

artículo científico publicado en 2003

Chemical and pathway proteomics: powerful tools for oncology drug discovery and personalized health care.

artículo científico publicado en 2008

Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes

artículo científico publicado en 2011

Chemoproteomics reveals time-dependent binding of histone deacetylase inhibitors to endogenous repressor complexes

artículo científico publicado en 2014

Chronic treatment with a novel γ-secretase modulator, JNJ-40418677, inhibits amyloid plaque formation in a mouse model of Alzheimer's disease.

artículo científico publicado en 2011

Computational Analysis of Alzheimer Amyloid Plaque Composition in 2D- and Elastically Reconstructed 3D-MALDI MS Images

artículo científico publicado en 2020

DMSO-enhanced MALDI MS imaging with normalization against a deuterated standard for relative quantification of dasatinib in serial mouse pharmacology studies.

artículo científico publicado en 2013

Determination of kinase inhibitor potencies in cell extracts by competition binding assays and isobaric mass tags

artículo científico publicado en 2012

Dimerization of the muscle-specific kinase induces tyrosine phosphorylation of acetylcholine receptors and their aggregation on the surface of myotubes

artículo científico publicado en 1998

Direct Automated MALDI Mass Spectrometry Analysis of Cellular Transporter Function: Inhibition of OATP2B1 Uptake by 294 Drugs

scientific article published on 12 August 2020

Discovery of a Highly Selective Tankyrase Inhibitor Displaying Growth Inhibition Effects against a Diverse Range of Tumor Derived Cell Lines.

artículo científico publicado en 2017

Emergence of whole-cell MALDI-MS biotyping for high-throughput bioanalysis of mammalian cells?

artículo científico publicado en 2013

Formation of postsynaptic-like membranes during differentiation of embryonic stem cells in vitro.

artículo científico publicado en 1998

Fourier Transform Infrared Microscopy Enables Guidance of Automated Mass Spectrometry Imaging to Predefined Tissue Morphologies.

artículo científico publicado en 2018

Heparin inhibits acetylcholine receptor aggregation at two distinct steps in the agrin-induced pathway.

artículo científico

Identification of serum proteins bound to industrial nanomaterials

artículo científico publicado en 2011

Imaging of complex sulfatides SM3 and SB1a in mouse kidney using MALDI-TOF/TOF mass spectrometry.

artículo científico publicado en 2011

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

artículo científico publicado en 2011

Inhibition of Rho-Associated Kinase 1/2 Attenuates Tumor Growth in Murine Gastric Cancer

artículo científico publicado en 2016

Label-free in situ monitoring of histone deacetylase drug target engagement by matrix-assisted laser desorption ionization-mass spectrometry biotyping and imaging.

artículo científico publicado en 2014

MALDI imaging MS reveals candidate lipid markers of polycystic kidney disease ⬇️

artículo científico publicado el 12 de julio de 2013

Mapping protein complexes using covalently linked antibodies and isobaric mass tags

scientific article published on 01 January 2014

Molecular imaging of brain localization of liposomes in mice using MALDI mass spectrometry.

artículo científico publicado en 2016

Monitoring CHO cell cultures: cell stress and early apoptosis assessment by mass spectrometry

artículo científico publicado en 2013

Murine Sialidase Neu3 facilitates GM2 degradation and bypass in mouse model of Tay-Sachs disease

artículo científico publicado en 2017

Myotubularin-related protein 7 inhibits insulin signaling in colorectal cancer

artículo científico publicado en 2016

Nitric oxide synthase (NOS-1) coclustered with agrin-induced AChR-specializations on cultured skeletal myotubes.

artículo científico publicado en 2000

Optimized chemical proteomics assay for kinase inhibitor profiling

artículo científico publicado en 2015

Pathway proteomics and chemical proteomics team up in drug discovery.

artículo científico publicado en 2007

Personalized monitoring of therapeutic salicylic acid in dried blood spots using a three-layer setup and desorption electrospray ionization mass spectrometry.

artículo científico publicado en 2015

Protein co-membership and biochemical affinity purifications

artículo científico publicado en 2006

Purification, pharmacological modulation, and biochemical characterization of interactors of endogenous human gamma-secretase

artículo científico publicado en 2009

Quantitative characterization of tissue globotetraosylceramides in a rat model of polycystic kidney disease by PrimaDrop sample preparation and indirect high-performance thin layer chromatography-matrix-assisted laser desorption/ionization-time-of-f

artículo científico publicado en 2013

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

artículo científico publicado en 2007

Quantitative imaging mass spectrometry of renal sulfatides: validation by classical mass spectrometric methods

artículo científico publicado en 2014

Recent developments of novel matrices and on-tissue chemical derivatization reagents for MALDI-MSI

artículo científico publicado en 2020

Renal sulfatides: sphingoid base-dependent localization and region-specific compensation of CerS2-dysfunction.

artículo científico publicado en 2014

Scores for standardization of on-tissue digestion of formalin-fixed paraffin-embedded tissue in MALDI-MS imaging

artículo científico publicado en 2016

Sensitive, robust and automated protein analysis of cell differentiation and of primary human blood cells by intact cell MALDI mass spectrometry biotyping ⬇️

artículo científico publicado el 6 de septiembre de 2012

Spatial Omics Imaging of Fresh-Frozen Tissue and Routine FFPE Histopathology of a Single Cancer Needle Core Biopsy: A Freezing Device and Multimodal Workflow

artículo científico publicado en 2023

Spatial distribution of endogenous tissue protease activity in gastric carcinoma mapped by MALDI mass spectrometry imaging

artículo científico publicado en 2018

Spatially resolved mass spectrometry analysis of amyloid plaque-associated lipids

scientific article published on 13 October 2020

Standardized processing of MALDI imaging raw data for enhancement of weak analyte signals in mouse models of gastric cancer and Alzheimer's disease.

artículo científico publicado en 2014

Structure-performance relationships of phenyl cinnamic acid derivatives as MALDI-MS matrices for sulfatide detection

artículo científico publicado en 2016

Studying epigenetic complexes and their inhibitors with the proteomics toolbox

artículo científico publicado en 2016

Sulfatides are required for renal adaptation to chronic metabolic acidosis

artículo científico publicado en 2013

The stress kinase GCN2 does not mediate suppression of antitumor T cell responses by tryptophan catabolism in experimental melanomas.

artículo científico publicado en 2016

Therapeutic drug monitoring in dried blood spots using liquid microjunction surface sampling and high resolution mass spectrometry

artículo científico publicado en 2016

Tyrosine phosphorylation of the muscle-specific kinase is exclusively induced by acetylcholine receptor-aggregating agrin fragments.

artículo científico publicado en 1998

mGluR1/5-dependent long-term depression requires the regulated ectodomain cleavage of neuronal pentraxin NPR by TACE.

artículo científico publicado en 2008

Lista de obras de Carsten Hopf

4-Phenyl-α-cyanocinnamic acid amide: screening for a negative ion matrix for MALDI-MS imaging of multiple lipid classes.

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiation

Affinity profiling of the cellular kinome for the nucleotide cofactors ATP, ADP, and GTP.

Altered mitochondrial and peroxisomal integrity in lipocalin-2-deficient mice with hepatic steatosis

Alzheimer's-Causing Mutations Shift Aβ Length by Destabilizing γ-Secretase-Aβn Interactions

Calcium-dependent maintenance of agrin-induced postsynaptic specializations.

Chemical and pathway proteomics: powerful tools for oncology drug discovery and personalized health care.

Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes

Chemoproteomics reveals time-dependent binding of histone deacetylase inhibitors to endogenous repressor complexes

Chronic treatment with a novel γ-secretase modulator, JNJ-40418677, inhibits amyloid plaque formation in a mouse model of Alzheimer's disease.

Computational Analysis of Alzheimer Amyloid Plaque Composition in 2D- and Elastically Reconstructed 3D-MALDI MS Images

DMSO-enhanced MALDI MS imaging with normalization against a deuterated standard for relative quantification of dasatinib in serial mouse pharmacology studies.

Determination of kinase inhibitor potencies in cell extracts by competition binding assays and isobaric mass tags

Dimerization of the muscle-specific kinase induces tyrosine phosphorylation of acetylcholine receptors and their aggregation on the surface of myotubes

Direct Automated MALDI Mass Spectrometry Analysis of Cellular Transporter Function: Inhibition of OATP2B1 Uptake by 294 Drugs

Discovery of a Highly Selective Tankyrase Inhibitor Displaying Growth Inhibition Effects against a Diverse Range of Tumor Derived Cell Lines.

Emergence of whole-cell MALDI-MS biotyping for high-throughput bioanalysis of mammalian cells?

Formation of postsynaptic-like membranes during differentiation of embryonic stem cells in vitro.

Fourier Transform Infrared Microscopy Enables Guidance of Automated Mass Spectrometry Imaging to Predefined Tissue Morphologies.

Heparin inhibits acetylcholine receptor aggregation at two distinct steps in the agrin-induced pathway.

Identification of serum proteins bound to industrial nanomaterials

Imaging of complex sulfatides SM3 and SB1a in mouse kidney using MALDI-TOF/TOF mass spectrometry.

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

Inhibition of Rho-Associated Kinase 1/2 Attenuates Tumor Growth in Murine Gastric Cancer

Label-free in situ monitoring of histone deacetylase drug target engagement by matrix-assisted laser desorption ionization-mass spectrometry biotyping and imaging.

MALDI imaging MS reveals candidate lipid markers of polycystic kidney disease ⬇️

Mapping protein complexes using covalently linked antibodies and isobaric mass tags

Molecular imaging of brain localization of liposomes in mice using MALDI mass spectrometry.

Monitoring CHO cell cultures: cell stress and early apoptosis assessment by mass spectrometry

Murine Sialidase Neu3 facilitates GM2 degradation and bypass in mouse model of Tay-Sachs disease

Myotubularin-related protein 7 inhibits insulin signaling in colorectal cancer

Nitric oxide synthase (NOS-1) coclustered with agrin-induced AChR-specializations on cultured skeletal myotubes.

Optimized chemical proteomics assay for kinase inhibitor profiling

Pathway proteomics and chemical proteomics team up in drug discovery.

Personalized monitoring of therapeutic salicylic acid in dried blood spots using a three-layer setup and desorption electrospray ionization mass spectrometry.

Protein co-membership and biochemical affinity purifications

Purification, pharmacological modulation, and biochemical characterization of interactors of endogenous human gamma-secretase

Quantitative characterization of tissue globotetraosylceramides in a rat model of polycystic kidney disease by PrimaDrop sample preparation and indirect high-performance thin layer chromatography-matrix-assisted laser desorption/ionization-time-of-f

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

Quantitative imaging mass spectrometry of renal sulfatides: validation by classical mass spectrometric methods

Recent developments of novel matrices and on-tissue chemical derivatization reagents for MALDI-MSI

Renal sulfatides: sphingoid base-dependent localization and region-specific compensation of CerS2-dysfunction.

Scores for standardization of on-tissue digestion of formalin-fixed paraffin-embedded tissue in MALDI-MS imaging

Sensitive, robust and automated protein analysis of cell differentiation and of primary human blood cells by intact cell MALDI mass spectrometry biotyping ⬇️

Spatial Omics Imaging of Fresh-Frozen Tissue and Routine FFPE Histopathology of a Single Cancer Needle Core Biopsy: A Freezing Device and Multimodal Workflow

Spatial distribution of endogenous tissue protease activity in gastric carcinoma mapped by MALDI mass spectrometry imaging

Spatially resolved mass spectrometry analysis of amyloid plaque-associated lipids

Standardized processing of MALDI imaging raw data for enhancement of weak analyte signals in mouse models of gastric cancer and Alzheimer's disease.

Structure-performance relationships of phenyl cinnamic acid derivatives as MALDI-MS matrices for sulfatide detection

Studying epigenetic complexes and their inhibitors with the proteomics toolbox

Sulfatides are required for renal adaptation to chronic metabolic acidosis

The stress kinase GCN2 does not mediate suppression of antitumor T cell responses by tryptophan catabolism in experimental melanomas.

Therapeutic drug monitoring in dried blood spots using liquid microjunction surface sampling and high resolution mass spectrometry

Tyrosine phosphorylation of the muscle-specific kinase is exclusively induced by acetylcholine receptor-aggregating agrin fragments.

mGluR1/5-dependent long-term depression requires the regulated ectodomain cleavage of neuronal pentraxin NPR by TACE.