Lista de obras - David Carling - Dominio Público Uruguay

140 Interaction of AMP-activated protein kinase subunits in the heterotrimeric complex and with their yeast homologues ⬇️

artículo científico publicado el 1 de noviembre de 1997

5'-AMP activates the AMP-activated protein kinase cascade, and Ca2+/calmodulin activates the calmodulin-dependent protein kinase I cascade, via three independent mechanisms

artículo científico publicado en 1995

5'-AMP-activated protein kinase is inactivated by adrenergic signalling in adult cardiac myocytes

artículo científico publicado en 2012

5'-AMP-activated protein kinase-activating transcription factor 1 cascade modulates human monocyte-derived macrophages to atheroprotective functions in response to heme or metformin

artículo científico publicado en 2013

A common bicyclic protein kinase cascade inactivates the regulatory enzymes of fatty acid and cholesterol biosynthesis

scientific article published on 01 November 1987

A conserved sequence immediately N-terminal to the Bateman domains in AMP-activated protein kinase gamma subunits is required for the interaction with the beta subunits.

artículo científico publicado en 2007

A dual role for AMP-activated protein kinase (AMPK) during neonatal hypoxic-ischaemic brain injury in mice

artículo científico publicado en 2015

A loss-of-function NUAK2 mutation in humans causes anencephaly due to impaired Hippo-YAP signaling

artículo científico publicado en 2020

ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase

artículo científico publicado en 2011

AMP-activated kinase regulates cytoplasmic HuR.

artículo científico publicado en 2002

AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to amyloid β-peptide exposure.

artículo científico publicado en 2011

AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes

artículo científico publicado en 2012

AMP-activated protein kinase plays a role in the control of food intake

artículo científico publicado en 2004

AMP-activated protein kinase: also regulated by ADP?

scientific article published on 23 July 2011

AMP-activated protein kinase: balancing the scales.

artículo científico publicado en 2005

AMP-activated protein kinase: nature's energy sensor

scientific article published on 18 July 2011

AMP-activated protein kinase: new regulation, new roles? ⬇️

artículo científico publicado el 1 de julio de 2012

AMP-activated protein kinase: the current landscape for drug development

scientific article published on 01 July 2019

AMPK activation protects against diet induced obesity through Ucp1-independent thermogenesis in subcutaneous white adipose tissue

artículo científico publicado en 2019

AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B.

artículo científico publicado en 2016

AMPK hierarchy: a matter of space and time

artículo científico publicado en 2019

AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons

artículo científico publicado en 2007

AMPK signalling in health and disease.

artículo científico publicado en 2017

AMPK, insulin resistance, and the metabolic syndrome

artículo científico publicado en 2013

AMPK.

artículo científico publicado en 2004

Absence of RIP140 reveals a pathway regulating glut4-dependent glucose uptake in oxidative skeletal muscle through UCP1-mediated activation of AMPK.

artículo científico publicado en 2012

Activation of AMP-activated protein kinase by vascular endothelial growth factor mediates endothelial angiogenesis independently of nitric-oxide synthase

artículo científico publicado en 2010

Activation of AMPK alpha- and gamma-isoform complexes in the intact ischemic rat heart

scientific journal article

Activation of glucose transport by AMP-activated protein kinase via stimulation of nitric oxide synthase

scientific article published on 01 December 2000

Adenosine monophosphate-activated protein kinase: hydroxymethylglutaryl-CoA reductase kinase.

artículo científico publicado en 1991

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

artículo científico publicado en 2002

Adiponectin-induced endothelial nitric oxide synthase activation and nitric oxide production are mediated by APPL1 in endothelial cells.

artículo científico publicado en 2007

Beyond energy homeostasis: the expanding role of AMP-activated protein kinase in regulating metabolism

artículo científico

Biochemical and genetic evaluation of the role of AMP-activated protein kinase in polysaccharide storage myopathy in Quarter Horses

artículo científico publicado en 2007

Branching out on AMPK Regulation

scientific article published on 01 January 2009

CAMKK2 Promotes Prostate Cancer Independently of AMPK via Increased Lipogenesis.

artículo científico publicado en 2018

CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK.

artículo científico publicado en 2006

Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

artículo científico publicado en 2005

Cell competition acts as a purifying selection to eliminate cells with mitochondrial defects during early mouse development

artículo científico publicado en 2021

Cellular energy sensor balances the scales

artículo científico publicado en 2004

Characterisation of 5'-AMP-activated protein kinase in human liver using specific peptide substrates and the effects of 5'-AMP analogues on enzyme activity

artículo científico publicado en 1994

Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding

artículo científico publicado en 2000

Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase

artículo científico publicado en 2000

Characterization of the role of gamma2 R531G mutation in AMP-activated protein kinase in cardiac hypertrophy and Wolff-Parkinson-White syndrome

artículo científico publicado en 2005

Characterization of the role of the AMP-activated protein kinase in the stimulation of glucose transport in skeletal muscle cells

artículo científico publicado en 2002

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function

artículo científico publicado en 2016

Defining the mechanism of activation of AMP-activated protein kinase by the small molecule A-769662, a member of the thienopyridone family.

artículo científico publicado en 2007

Deletion of Lkb1 in pro-opiomelanocortin neurons impairs peripheral glucose homeostasis in mice

artículo científico publicado en 2011

Determination of AMP-activated protein kinase phosphorylation sites in recombinant protein expressed using the pET28a vector: a cautionary tale

artículo científico publicado en 2009

Diurnal rhythm of phosphorylation of rat liver acetyl-CoA carboxylase by the AMP-activated protein kinase, demonstrated using freeze-clamping. Effects of high fat diets

artículo científico publicado en 1992

Dual regulation of the AMP-activated protein kinase provides a novel mechanism for the control of creatine kinase in skeletal muscle.

artículo científico publicado en 1998

Effect of different γ-subunit isoforms on the regulation of AMPK

artículo científico publicado en 2017

Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism

artículo científico publicado en 1989

Evidence that the AMP-activated protein kinase stimulates rat liver carnitine palmitoyltransferase I by phosphorylating cytoskeletal components

artículo científico publicado en 1998

Exercise in rats does not alter hypothalamic AMP-activated protein kinase activity

artículo científico publicado en 2005

Fluorescence lifetime readouts of Troponin-C-based calcium FRET sensors: a quantitative comparison of CFP and mTFP1 as donor fluorophores.

artículo científico publicado en 2012

Functional analysis of mutations in the gamma 2 subunit of AMP-activated protein kinase associated with cardiac hypertrophy and Wolff-Parkinson-White syndrome.

artículo científico publicado en 2002

Glucokinase activity in the arcuate nucleus regulates glucose intake

artículo científico publicado en 2014

Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation

artículo científico publicado en 2002

Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

artículo científico publicado en 2010

Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin.

artículo científico publicado en 2008

Identification of a Novel AMP-activated Protein Kinase β Subunit Isoform That Is Highly Expressed in Skeletal Muscle ⬇️

artículo científico publicado el 15 de mayo de 1998

Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis

artículo científico publicado en 2003

Imaging of Metabolic Status in 3D Cultures with an Improved AMPK FRET Biosensor for FLIM.

scientific article published on 19 August 2016

Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function

artículo científico publicado en 2003

Indisulam targets RNA splicing and metabolism to serve as a therapeutic strategy for high-risk neuroblastoma

artículo científico publicado en 2022

Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491.

artículo científico publicado en 2005

Investigating the regulation of brain-specific kinases 1 and 2 by phosphorylation

artículo científico publicado en 2008

Isoform-specific AMPK association with TBC1D1 is reduced by a mutation associated with severe obesity

artículo científico publicado en 2018

Isoform-specific regulation of 5' AMP-activated protein kinase in skeletal muscle from obese Zucker (fa/fa) rats in response to contraction

artículo científico publicado en 2002

LKB1 is an essential regulator of spermatozoa release during spermiation in the mammalian testis

artículo científico publicado en 2011

LKB1 is required for hepatic bile acid transport and canalicular membrane integrity in mice

artículo científico publicado en 2011

LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

scientific journal article

LKB1: a sweet side to Peutz-Jeghers syndrome?

artículo científico publicado en 2006

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

artículo científico publicado en 2002

Liver-Specific Activation of AMPK Prevents Steatosis on a High-Fructose Diet

artículo científico publicado en 2017

Loss of AMP-activated protein kinase alpha2 subunit in mouse beta-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia.

artículo científico publicado en 2010

Low utilization of circulating glucose after food withdrawal in Snell dwarf mice

artículo científico publicado en 2007

Mammalian γ2 AMPK regulates intrinsic heart rate

artículo científico publicado en 2017

Metabolic and mitogenic signal transduction in human skeletal muscle after intense cycling exercise

article

Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly

scientific article published in Journal of Biological Chemistry

Molecular Dissection of Pro-Fibrotic IL11 Signaling in Cardiac and Pulmonary Fibroblasts

artículo científico publicado en 2021

Molecular characterization of the AMP-activated protein kinase and its role in cellular metabolism.

artículo científico publicado en 1997

Molecular cloning, expression and chromosomal localisation of human AMP-activated protein kinase

artículo científico publicado en 1994

Muscarinic receptor activation of AMP-activated protein kinase inhibits orexigenic neuropeptide mRNA expression.

artículo científico publicado en 2008

Mutation of Fnip1 is associated with B-cell deficiency, cardiomyopathy, and elevated AMPK activity.

artículo científico publicado en 2016

Negative interactions between phosphorylation of acetyl-CoA carboxylase by the cyclic AMP-dependent and AMP-activated protein kinases

scientific article published on 01 August 1988

Neuregulin signaling on glucose transport in muscle cells

scientific journal article

Phospho-dependent functional modulation of GABA(B) receptors by the metabolic sensor AMP-dependent protein kinase.

artículo científico publicado en 2007

Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia

artículo científico publicado en 2000

Phosphorylation of AMPK by upstream kinases is required for activity in mammalian cells

artículo científico

Phosphorylation of bovine hormone-sensitive lipase by the AMP-activated protein kinase. A possible antilipolytic mechanism

artículo científico publicado en 1989

Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation ⬇️

artículo científico publicado el 17 de junio de 2013

Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495

scientific article published on 01 September 2020

Protein kinase inhibitors block the stimulation of the AMP-activated protein kinase by 5-amino-4-imidazolecarboxamide riboside.

artículo científico publicado en 2002

Purification of the AMP-activated protein kinase on ATP-gamma-sepharose and analysis of its subunit structure.

artículo científico publicado en 1994

Ribosomal S6K1 in POMC and AgRP Neurons Regulates Glucose Homeostasis but Not Feeding Behavior in Mice

artículo científico publicado en 2015

Roles of the Snf1/Rkin1/AMP-activated protein kinase family in the response to environmental and nutritional stress.

artículo científico publicado en 1994

S6 kinase deletion suppresses muscle growth adaptations to nutrient availability by activating AMP kinase

artículo científico publicado en 2007

Salicylates Ameliorate Intestinal Inflammation by Activating Macrophage AMPK

artículo científico publicado en 2020

Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation

artículo científico publicado en 2010

Structural basis for AMP binding to mammalian AMP-activated protein kinase

artículo científico publicado en 2007

Structural basis of AMPK regulation by small molecule activators

artículo científico publicado en 2013

Structure of mammalian AMPK and its regulation by ADP

artículo científico publicado en 2011

Taking the stress out of melanoma

artículo científico publicado en 2009

The AMP-activated protein kinase cascade--a unifying system for energy control

artículo científico publicado en 2004

The AMP-activated protein kinase α2 catalytic subunit controls whole-body insulin sensitivity

article by Benoit Viollet et al published 1 January 2003 in Journal of Clinical Investigation

The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell?

artículo científico publicado en 1998

The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways.

artículo científico publicado en 2002

The SNF1 kinase complex from Saccharomyces cerevisiae phosphorylates the transcriptional repressor protein Mig1p in vitro at four sites within or near regulatory domain 1

artículo científico publicado en 1999

The alpha1 and alpha2 isoforms of the AMP-activated protein kinase have similar activities in rat liver but exhibit differences in substrate specificity in vitro

scientific journal article

The mammalian AMP-activated protein kinase complex mediates glucose regulation of gene expression in the yeast Saccharomyces cerevisiae

article

The novel choline kinase inhibitor ICL-CCIC-0019 reprograms cellular metabolism and inhibits cancer cell growth.

artículo científico publicado en 2016

The regulation and function of mammalian AMPK-related kinases.

scientific article published on 19 February 2009

The regulation of AMP-activated protein kinase by phosphorylation

artículo científico publicado en 2000

The regulation of AMP-activated protein kinase by upstream kinases.

artículo científico publicado en 2008

The role of ATM in response to metformin treatment and activation of AMPK

artículo científico publicado en 2012

The role of phosphorylation/dephosphorylation of acetyl-CoA carboxylase in the regulation of mammalian fatty acid biosynthesis

artículo científico publicado en 1986

The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism

artículo científico publicado en 2014

The substrate and sequence specificity of the AMP-activated protein kinase. Phosphorylation of glycogen synthase and phosphorylase kinase

scientific article published on 01 June 1989

Thrombin activates AMP-activated protein kinase in endothelial cells via a pathway involving Ca2+/calmodulin-dependent protein kinase kinase beta

artículo científico publicado en 2006

Time-lapse 3-D measurements of a glucose biosensor in multicellular spheroids by light sheet fluorescence microscopy in commercial 96-well plates

artículo científico publicado en 2016

Transgenic mouse model of ventricular preexcitation and atrioventricular reentrant tachycardia induced by an AMP-activated protein kinase loss-of-function mutation responsible for Wolff-Parkinson-White syndrome.

artículo científico publicado en 2004

Tumor necrosis factor alpha-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling

artículo científico publicado en 2006

Lista de obras de David Carling

140 Interaction of AMP-activated protein kinase subunits in the heterotrimeric complex and with their yeast homologues ⬇️

5'-AMP activates the AMP-activated protein kinase cascade, and Ca2+/calmodulin activates the calmodulin-dependent protein kinase I cascade, via three independent mechanisms

5'-AMP-activated protein kinase is inactivated by adrenergic signalling in adult cardiac myocytes

5'-AMP-activated protein kinase-activating transcription factor 1 cascade modulates human monocyte-derived macrophages to atheroprotective functions in response to heme or metformin

A common bicyclic protein kinase cascade inactivates the regulatory enzymes of fatty acid and cholesterol biosynthesis

A conserved sequence immediately N-terminal to the Bateman domains in AMP-activated protein kinase gamma subunits is required for the interaction with the beta subunits.

A dual role for AMP-activated protein kinase (AMPK) during neonatal hypoxic-ischaemic brain injury in mice

A loss-of-function NUAK2 mutation in humans causes anencephaly due to impaired Hippo-YAP signaling

ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase

AMP-activated kinase regulates cytoplasmic HuR.

AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to amyloid β-peptide exposure.

AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes

AMP-activated protein kinase plays a role in the control of food intake

AMP-activated protein kinase: also regulated by ADP?

AMP-activated protein kinase: balancing the scales.

AMP-activated protein kinase: nature's energy sensor

AMP-activated protein kinase: new regulation, new roles? ⬇️

AMP-activated protein kinase: the current landscape for drug development

AMPK activation protects against diet induced obesity through Ucp1-independent thermogenesis in subcutaneous white adipose tissue

AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B.

AMPK hierarchy: a matter of space and time

AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons

AMPK signalling in health and disease.

AMPK, insulin resistance, and the metabolic syndrome

AMPK.

Absence of RIP140 reveals a pathway regulating glut4-dependent glucose uptake in oxidative skeletal muscle through UCP1-mediated activation of AMPK.

Activation of AMP-activated protein kinase by vascular endothelial growth factor mediates endothelial angiogenesis independently of nitric-oxide synthase

Activation of AMPK alpha- and gamma-isoform complexes in the intact ischemic rat heart

Activation of glucose transport by AMP-activated protein kinase via stimulation of nitric oxide synthase

Adenosine monophosphate-activated protein kinase: hydroxymethylglutaryl-CoA reductase kinase.

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

Adiponectin-induced endothelial nitric oxide synthase activation and nitric oxide production are mediated by APPL1 in endothelial cells.

Beyond energy homeostasis: the expanding role of AMP-activated protein kinase in regulating metabolism

Biochemical and genetic evaluation of the role of AMP-activated protein kinase in polysaccharide storage myopathy in Quarter Horses

Branching out on AMPK Regulation

CAMKK2 Promotes Prostate Cancer Independently of AMPK via Increased Lipogenesis.

CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK.

Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

Cell competition acts as a purifying selection to eliminate cells with mitochondrial defects during early mouse development

Cellular energy sensor balances the scales

Characterisation of 5'-AMP-activated protein kinase in human liver using specific peptide substrates and the effects of 5'-AMP analogues on enzyme activity

Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding

Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase

Characterization of the role of gamma2 R531G mutation in AMP-activated protein kinase in cardiac hypertrophy and Wolff-Parkinson-White syndrome

Characterization of the role of the AMP-activated protein kinase in the stimulation of glucose transport in skeletal muscle cells

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function

Defining the mechanism of activation of AMP-activated protein kinase by the small molecule A-769662, a member of the thienopyridone family.

Deletion of Lkb1 in pro-opiomelanocortin neurons impairs peripheral glucose homeostasis in mice

Determination of AMP-activated protein kinase phosphorylation sites in recombinant protein expressed using the pET28a vector: a cautionary tale

Diurnal rhythm of phosphorylation of rat liver acetyl-CoA carboxylase by the AMP-activated protein kinase, demonstrated using freeze-clamping. Effects of high fat diets

Dual regulation of the AMP-activated protein kinase provides a novel mechanism for the control of creatine kinase in skeletal muscle.

Effect of different γ-subunit isoforms on the regulation of AMPK

Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism

Evidence that the AMP-activated protein kinase stimulates rat liver carnitine palmitoyltransferase I by phosphorylating cytoskeletal components

Exercise in rats does not alter hypothalamic AMP-activated protein kinase activity

Fluorescence lifetime readouts of Troponin-C-based calcium FRET sensors: a quantitative comparison of CFP and mTFP1 as donor fluorophores.

Functional analysis of mutations in the gamma 2 subunit of AMP-activated protein kinase associated with cardiac hypertrophy and Wolff-Parkinson-White syndrome.

Glucokinase activity in the arcuate nucleus regulates glucose intake

Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation

Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin.

Identification of a Novel AMP-activated Protein Kinase β Subunit Isoform That Is Highly Expressed in Skeletal Muscle ⬇️

Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis

Imaging of Metabolic Status in 3D Cultures with an Improved AMPK FRET Biosensor for FLIM.

Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function

Indisulam targets RNA splicing and metabolism to serve as a therapeutic strategy for high-risk neuroblastoma

Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491.

Investigating the regulation of brain-specific kinases 1 and 2 by phosphorylation

Isoform-specific AMPK association with TBC1D1 is reduced by a mutation associated with severe obesity

Isoform-specific regulation of 5' AMP-activated protein kinase in skeletal muscle from obese Zucker (fa/fa) rats in response to contraction

LKB1 is an essential regulator of spermatozoa release during spermiation in the mammalian testis

LKB1 is required for hepatic bile acid transport and canalicular membrane integrity in mice

LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

LKB1: a sweet side to Peutz-Jeghers syndrome?

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

Liver-Specific Activation of AMPK Prevents Steatosis on a High-Fructose Diet

Loss of AMP-activated protein kinase alpha2 subunit in mouse beta-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia.

Low utilization of circulating glucose after food withdrawal in Snell dwarf mice

Mammalian γ2 AMPK regulates intrinsic heart rate