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Lista de obras de Keith Shearwin

A mathematical model for transcriptional interference by RNA polymerase traffic in Escherichia coli

artículo científico publicado en 2004

A quantitative binding model for the Apl protein, the dual purpose recombination-directionality factor and lysis-lysogeny regulator of bacteriophage 186

scientific article published on 13 August 2020

AMHY and sex determination in egg-laying mammals

artículo científico publicado en 2024

APTC-C-SA01: A Novel Bacteriophage Cocktail Targeting <i>Staphylococcus aureus</i> and MRSA Biofilms

artículo científico publicado en 2022

Advanced Resistance Studies Identify Two Discrete Mechanisms in Staphylococcus aureus to Overcome Antibacterial Compounds that Target Biotin Protein Ligase

scientific article published on 06 April 2020

Allowance for thermodynamic nonideality and Donnan effects in binding studies. Activity coefficients of charged ligands in the presence of albumin

artículo científico publicado en 1990

Analysis of Infection Time Courses Shows CII Levels Determine the Frequency of Lysogeny in Phage 186

artículo científico publicado en 2021

Aspects of protein-DNA interactions: a review of quantitative thermodynamic theory for modelling synthetic circuits utilising LacI and CI repressors, IPTG and the reporter gene lacZ.

artículo científico publicado en 2016

Bacteriophage lambda repressor mediates the formation of a complex enhancer-like structure

artículo científico publicado en 2013

Biotin-mediated growth and gene expression in Staphylococcus aureus is highly responsive to environmental biotin.

artículo científico publicado en 2018

Characterizing Transcriptional Interference between Converging Genes in Bacteria

scientific article published on 14 February 2019

Clonetegration Using OSIP Plasmids: One-Step DNA Assembly and Site-Specific Genomic Integration in Bacteria.

artículo científico publicado en 2017

Combining random microseed matrix screening and the magic triangle for the efficient structure solution of a potential lysin from bacteriophage P68

artículo científico publicado en 2019

Cooperativity in long-range gene regulation by the lambda CI repressor.

artículo científico publicado en 2004

Cro's role in the CI Cro bistable switch is critical for {lambda}'s transition from lysogeny to lytic development

artículo científico publicado en 2007

Derivatization of Protein Crystals with I3C using Random Microseed Matrix Screening

artículo científico publicado en 2021

Directing traffic on DNA-How transcription factors relieve or induce transcriptional interference.

artículo científico publicado en 2017

Effect of calcium ion on the dimerization of alpha-chymotrypsin

artículo científico publicado en 1990

Effect of colchicine analogues on the dissociation of alpha beta tubulin into subunits: the locus of colchicine binding

artículo científico publicado en 1994

Effects of thermodynamic nonideality on the kinetics of ester hydrolysis by alpha-chymotrypsin: a model system with preexistence of the isomerization equilibrium.

artículo científico publicado en 1989

Efficient O-demethylation of lignin monoaromatics using the peroxygenase activity of cytochrome P450 enzymes

artículo científico publicado en 2022

Efficient chromosomal-scale DNA looping in Escherichia coli using multiple DNA-looping elements

artículo científico publicado en 2017

Enhancer-like long-range transcriptional activation by λ CI-mediated DNA looping

artículo científico publicado en 2013

Establishing lysogenic transcription in the temperate coliphage 186.

artículo científico publicado en 2001

Functional alignment of regulatory networks: a study of temperate phages

artículo científico publicado en 2005

Hidden Secrets of Sigma54 Promoters Revealed

artículo científico publicado en 2017

Identification of residues in the N-terminal PAS domains important for dimerization of Arnt and AhR.

artículo científico publicado en 2011

Instability of CII is needed for efficient switching between lytic and lysogenic development in bacteriophage 186

artículo científico publicado en 2020

Linkage between ligand binding and control of tubulin conformation

artículo científico publicado en 1992

Linkages between the dissociation of alpha beta tubulin into subunits and ligand binding: the ground state of tubulin is the GDP conformation.

artículo científico publicado en 1994

Mechanisms of biotin-regulated gene expression in microbes

artículo científico publicado en 2016

Modelling transcriptional interference and DNA looping in gene regulation.

artículo científico publicado en 2007

Native mass spectrometry identifies an alternative DNA-binding pathway for BirA from Staphylococcus aureus

scientific article published on 26 February 2019

One-step cloning and chromosomal integration of DNA.

artículo científico publicado en 2013

Overcoming bacteriophage insensitivity in Staphylococcus aureus using clindamycin and azithromycinat subinhibitory concentrations

artículo científico publicado en 2021

Overcoming bacteriophage insensitivity in Staphylococcus aureus using clindamycin and azithromycinat subinhibitory concentrations

artículo científico publicado en 2021

Positive and Negative Control of Enhancer-Promoter Interactions by Other DNA Loops Generates Specificity and Tunability

scientific article published on 01 February 2019

Potent transcriptional interference by pausing of RNA polymerases over a downstream promoter

artículo científico publicado en 2009

Programmable DNA looping using engineered bivalent dCas9 complexes

artículo científico publicado en 2017

Promoter activation by CII, a potent transcriptional activator from bacteriophage 186.

artículo científico publicado en 2014

Prophages encoding human immune evasion cluster genes are enriched in isolated from chronic rhinosinusitis patients with nasal polyps

artículo científico publicado en 2021

Proteins mediating different DNA topologies block RNAP elongation with different efficiency

artículo científico publicado en 2022

Purification of bacteriophage lambda repressor

artículo científico publicado en 2013

Quantitation of interactions between two DNA loops demonstrates loop domain insulation in E. coli cells

artículo científico publicado en 2014

Quantitation of the DNA tethering effect in long-range DNA looping in vivo and in vitro using the Lac and λ repressors.

artículo científico publicado en 2013

RNA polymerase efficiently transcribes through DNA-scaffolded, cooperative bacteriophage repressor complexes

artículo científico publicado en 2022

RNA polymerase pausing at a protein roadblock can enhance transcriptional interference by promoter occlusion

scientific article published on 29 March 2019

Repurposing site-specific recombinases for synthetic biology

artículo científico publicado en 2013

Revisited gene regulation in bacteriophage lambda.

artículo científico publicado en 2005

Road rules for traffic on DNA-systematic analysis of transcriptional roadblocking in vivo.

artículo científico publicado en 2014

Simplified heavy-atom derivatization of protein structures via co-crystallization with the MAD tetragon tetrabromoterephthalic acid

artículo científico publicado en 2021

Single molecule analysis of DNA wrapping and looping by a circular 14mer wheel of the bacteriophage 186 CI repressor

artículo científico publicado en 2013

Slow growth leads to a switch.

artículo científico publicado en 2009

Substrate as a source of thermodynamic nonideality in enzyme kinetic studies: invertase-catalyzed hydrolysis of sucrose

scientific article published on 01 February 1988

The Tum protein of coliphage 186 is an antirepressor

artículo científico publicado en 1998

The helix-turn-helix motif of the coliphage 186 immunity repressor binds to two distinct recognition sequences

artículo científico publicado en 2001

The loopometer: a quantitative in vivo assay for DNA-looping proteins

artículo científico publicado en 2021

The pIT5 Plasmid Series, an Improved Toolkit for Repeated Genome Integration in E. coli

artículo científico publicado en 2021

The role of individual Nedd4-2 (KIAA0439) WW domains in binding and regulating epithelial sodium channels

artículo científico publicado en 2002

The role of repressor kinetics in relief of transcriptional interference between convergent promoters

artículo científico publicado en 2016

The structural basis of cooperative regulation at an alternate genetic switch

scientific article published on 01 March 2006

Thermodynamic nonideality as a probe of reversible protein unfolding effected by variations in pH and temperature: studies of ribonuclease

scientific article published on 01 November 1990

Thermodynamic nonideality in macromolecular solutions. Evaluation of parameters for the prediction of covolume effects

artículo científico publicado en 1990

Transcriptional interference between convergent promoters caused by elongation over the promoter

artículo científico publicado en 2004

Transcriptional interference by RNA polymerase pausing and dislodgement of transcription factors.

artículo científico publicado en 2011

Transcriptional interference--a crash course

artículo científico publicado en 2005