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Lista de obras de Clifford J. Woolf

5,6-EET is released upon neuronal activity and induces mechanical pain hypersensitivity via TRPA1 on central afferent terminals

artículo científico publicado en 2012

A Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal Growth Program

artículo científico publicado en 2016

A conditional deletion of the NR1 subunit of the NMDA receptor in adult spinal cord dorsal horn reduces NMDA currents and injury-induced pain

scientific journal article

A functionally characterized test set of human induced pluripotent stem cells

artículo científico publicado en 2011

A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene

artículo científico publicado en 2010

A novel tool for the assessment of pain: validation in low back pain

artículo científico publicado en 2009

A small molecule screen in stem-cell-derived motor neurons identifies a kinase inhibitor as a candidate therapeutic for ALS.

artículo científico publicado en 2013

A three-dimensional human neural cell culture model of Alzheimer's disease

artículo científico publicado en 2014

ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair

scientific article published on 14 January 2019

ATF3 expression improves motor function in the ALS mouse model by promoting motor neuron survival and retaining muscle innervation

scientific article published on 13 January 2014

ATF3 increases the intrinsic growth state of DRG neurons to enhance peripheral nerve regeneration

artículo científico publicado en 2007

Accelerating axonal growth promotes motor recovery after peripheral nerve injury in mice

artículo científico publicado en 2011

Activity-dependent silencing reveals functionally distinct itch-generating sensory neurons ⬇️

artículo científico publicado el 19 de mayo de 2013

Analgesia by inhibiting tetrahydrobiopterin synthesis ⬇️

artículo científico publicado el 15 de diciembre de 2011

Association of Joint Inflammation With Pain Sensitization in Knee Osteoarthritis: The Multicenter Osteoarthritis Study

artículo científico publicado en 2015

Author Correction: Commensal microflora-induced T cell responses mediate progressive neurodegeneration in glaucoma

scientific article published in Nature Communications

Axonal G3BP1 stress granule protein limits axonal mRNA translation and nerve regeneration

artículo científico publicado en 2018

Axonal injury-dependent induction of the peripheral benzodiazepine receptor in small-diameter adult rat primary sensory neurons

scientific journal article

BACE1 regulates voltage-gated sodium channels and neuronal activity

artículo científico publicado en 2007

Bacteria activate sensory neurons that modulate pain and inflammation

scientific article published on 21 August 2013

Blocking caspase activity prevents transsynaptic neuronal apoptosis and the loss of inhibition in lamina II of the dorsal horn after peripheral nerve injury.

artículo científico publicado en 2005

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

artículo científico publicado en 2006

Bradykinin and peripheral sensitization

artículo científico publicado en 2006

Bradykinin enhances AMPA and NMDA receptor activity in spinal cord dorsal horn neurons by activating multiple kinases to produce pain hypersensitivity

artículo científico publicado en 2008

Bradykinin produces pain hypersensitivity by potentiating spinal cord glutamatergic synaptic transmission.

artículo científico publicado en 2005

Brain Responses to Noxious Stimuli in Patients With Chronic Pain: A Systematic Review and Meta-analysis

artículo científico publicado en 2021

Breaking barriers to novel analgesic drug development

artículo científico publicado en 2017

Breaking barriers to novel analgesic drug development

artículo científico publicado en 2017

Bupivacaine-induced cellular entry of QX-314 and its contribution to differential nerve block.

artículo científico publicado en 2014

CD11b+Ly6G- myeloid cells mediate mechanical inflammatory pain hypersensitivity.

artículo científico publicado en 2015

CLP1 links tRNA metabolism to progressive motor-neuron loss

artículo científico publicado en 2013

CNS injury: IL-33 sounds the alarm

artículo científico publicado en 2015

COX2 in CNS neural cells mediates mechanical inflammatory pain hypersensitivity in mice

artículo científico publicado en 2009

Can we conquer pain?

artículo científico publicado en 2002

Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors

artículo científico publicado en 2007

Capsaicin combined with local anesthetics preferentially prolongs sensory/nociceptive block in rat sciatic nerve

artículo científico publicado en 2008

Capturing Novel Non-opioid Pain Targets

scientific article published on 29 June 2019

Casting light on pain.

artículo científico publicado en 2014

Central changes in primary afferent fibers following peripheral nerve lesions

artículo científico publicado en 1997

Central sensitization and LTP: do pain and memory share similar mechanisms?

artículo científico publicado en 2003

Central sensitization: a generator of pain hypersensitivity by central neural plasticity

artículo científico publicado en 2009

Coapplication of lidocaine and the permanently charged sodium channel blocker QX-314 produces a long-lasting nociceptive blockade in rodents

artículo científico publicado en 2009

Collateral sprouting of uninjured primary afferent A-fibers into the superficial dorsal horn of the adult rat spinal cord after topical capsaicin treatment to the sciatic nerve

artículo científico publicado en 1996

Commensal microflora-induced T cell responses mediate progressive neurodegeneration in glaucoma

artículo científico publicado en 2018

Complement induction in spinal cord microglia results in anaphylatoxin C5a-mediated pain hypersensitivity

artículo científico publicado en 2007

Composite Pain Biomarker Signatures for Objective Assessment and Effective Treatment

scientific article published on 01 March 2019

Considerations for extrapolating evidence of acute and chronic pain analgesic efficacy ⬇️

artículo científico publicado el 10 de marzo de 2011

Construction of a global pain systems network highlights phospholipid signaling as a regulator of heat nociception

artículo científico publicado en 2012

Convergent neural representations of experimentally-induced acute pain in healthy volunteers: A large-scale fMRI meta-analysis

scientific article published on 15 January 2020

Conversion of mouse and human fibroblasts into functional spinal motor neurons

artículo científico publicado en 2011

Correction: Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity

artículo científico publicado en 2015

DRAGON, a bone morphogenetic protein co-receptor

artículo científico publicado en 2005

DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties

artículo científico publicado en 2004

Deconstructing the Neuropathic Pain Phenotype to Reveal Neural Mechanisms ⬇️

artículo científico publicado el 23 de febrero de 2012

Decreased alertness due to sleep loss increases pain sensitivity in mice.

artículo científico publicado en 2017

Delayed sympathetic dependence in the spared nerve injury (SNI) model of neuropathic pain

artículo científico publicado en 2007

Detection of cold pain, cold allodynia and cold hyperalgesia in freely behaving rats

artículo científico publicado en 2005

Developing nociceptor-selective treatments for acute and chronic pain

Development of neuropathic pain in the rat spared nerve injury model is not prevented by a peripheral nerve block

artículo científico publicado en 2003

Developmental expression of the TTX-resistant voltage-gated sodium channels Nav1.8 (SNS) and Nav1.9 (SNS2) in primary sensory neurons.

artículo científico publicado en 2001

Differential analgesic sensitivity of two distinct neuropathic pain models

artículo científico publicado en 2004

Diltiazem Promotes Regenerative Axon Growth

artículo científico publicado en 2018

Diminished Schwann cell repair responses underlie age-associated impaired axonal regeneration

artículo científico

Disruption of ErbB receptor signaling in adult non-myelinating Schwann cells causes progressive sensory loss

artículo científico publicado en 2003

Doublecortin-Like Kinases Promote Neuronal Survival and Induce Growth Cone Reformation via Distinct Mechanisms.

artículo científico publicado en 2015

Dynamic changes in glypican-1 expression in dorsal root ganglion neurons after peripheral and central axonal injury

artículo científico publicado en 2004

Dynamic receptive field plasticity in rat spinal cord dorsal horn following C-primary afferent input

artículo científico publicado en 1987

ERK MAP kinase activation in superficial spinal cord neurons induces prodynorphin and NK-1 upregulation and contributes to persistent inflammatory pain hypersensitivity.

artículo científico publicado en 2002

ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model

article

Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial

artículo científico publicado en 2020

Endogenous opioid peptides and pain mechanisms: a complex relationship

artículo científico publicado en 1983

Enhanced Neuronal Regeneration in the CAST/Ei Mouse Strain Is Linked to Expression of Differentiation Markers after Injury

artículo científico

Ensuring transparency and minimization of methodologic bias in preclinical pain research: PPRECISE considerations

artículo científico publicado en 2016

Epineural optogenetic activation of nociceptors initiates and amplifies inflammation

scientific article published on 21 September 2020

Exploiting microarrays to reveal differential gene expression in the nervous system

artículo científico publicado en 2003

From Dish to Bedside: Lessons Learned While Translating Findings from a Stem Cell Model of Disease to a Clinical Trial

artículo científico publicado en 2015

GAP-43 expression in primary sensory neurons following central axotomy.

artículo científico publicado en 1994

GCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial function

artículo científico publicado en 2008

GDNF selectively promotes regeneration of injury-primed sensory neurons in the lesioned spinal cord

artículo científico publicado en 2007

GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence

scientific journal article

Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity

artículo científico publicado en 2012

Heat Shock Protein 27: Developmental Regulation and Expression after Peripheral Nerve Injury ⬇️

artículo científico publicado el 1 de agosto de 1998

High basal expression and injury-induced down regulation of two regulator of G-protein signaling transcripts, RGS3 and RGS4 in primary sensory neurons ⬇️

artículo científico publicado el 1 de septiembre de 2003

Hsp27 upregulation and phosphorylation is required for injured sensory and motor neuron survival

artículo científico publicado en 2002

Induction of the Oct-2 transcription factor in primary sensory neurons during inflammation is nerve growth factor-dependent

scientific article published on 01 February 1996

Inflammation-induced decrease in voluntary wheel running in mice: a nonreflexive test for evaluating inflammatory pain and analgesia.

artículo científico publicado en 2012

Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary sensory neurons.

artículo científico publicado en 1996

Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers

artículo científico publicado en 2007

Inhibition of the kinase WNK1/HSN2 ameliorates neuropathic pain by restoring GABA inhibition

artículo científico publicado en 2016

Injury-induced decline of intrinsic regenerative ability revealed by quantitative proteomics

artículo científico publicado en 2015

Injury-induced plasticity of the flexor reflex in chronic decerebrate rats

article by C J Woolf & Stephen B McMahon published 1 October 1985 in Neuroscience

Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons

artículo científico publicado en 2014

Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization.

artículo científico publicado en 2004

Lack of motor recovery after prolonged denervation of the neuromuscular junction is not due to regenerative failure.

artículo científico publicado en 2015

Leukemia Inhibitory Factor Is an Anti-Inflammatory and Analgesic Cytokine ⬇️

artículo científico publicado el 15 de julio de 1998

Localization and action of Dragon (repulsive guidance molecule b), a novel bone morphogenetic protein coreceptor, throughout the reproductive axis.

artículo científico publicado en 2005

Loss of inhibitory interneurons in the dorsal spinal cord and elevated itch in Bhlhb5 mutant mice.

artículo científico publicado en 2010

Low-dose methotrexate reduces peripheral nerve injury-evoked spinal microglial activation and neuropathic pain behavior in rats

artículo científico publicado en 2008

Mechanistic Differences in Neuropathic Pain Modalities Revealed by Correlating Behavior with Global Expression Profiling.

artículo científico publicado en 2018

Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts.

artículo científico publicado en 2014

Morphine, the NMDA receptor antagonist MK801 and the tachykinin NK1 receptor antagonist RP67580 attenuate the development of inflammation-induced progressive tactile hypersensitivity ⬇️

artículo científico publicado el 1 de julio de 1998

Mouse embryonic stem cells can differentiate via multiple paths to the same state.

artículo científico publicado en 2017

Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1

artículo científico publicado en 2010

Mutant SPTLC1 dominantly inhibits serine palmitoyltransferase activity in vivo and confers an age-dependent neuropathy

artículo científico publicado en 2005

Neurite Collapse and Altered ER Ca Control in Human Parkinson Disease Patient iPSC-Derived Neurons with LRRK2 G2019S Mutation

artículo científico publicado en 2018

Neurogenic Inflammation – The Peripheral Nervous System’s Role in Host Defense and Immunopathology

artículo científico publicado en 2012

Neuroimmunity: Physiology and Pathology

artículo científico publicado en 2016

Neuronal Circuits Modulate Antigen Flow Through Lymph Nodes

artículo científico publicado en 2016

Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration

artículo científico publicado en 2018

Neuropathic pain: a maladaptive response of the nervous system to damage

scientific article published on January 2009

Neurotrophins: peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivity

artículo científico publicado en 1999

No DREAM, No pain. Closing the spinal gate

artículo científico publicado en 2002

Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity

artículo científico publicado en 1999

Nociceptor neuroimmune interactomes reveal cell type- and injury-specific inflammatory pain pathways

Nociceptors are interleukin-1beta sensors

artículo científico publicado en 2008

Nociceptors--noxious stimulus detectors

artículo científico publicado en 2007

Non-surgical mouse model of endometriosis-associated pain that responds to clinically active drugs

artículo científico publicado en 2020

Novel charged sodium and calcium channel inhibitor active against neurogenic inflammation

artículo científico publicado en 2019

Noxious stimuli induce an N-methyl-D-aspartate receptor-dependent hypersensitivity of the flexion withdrawal reflex to touch: implications for the treatment of mechanical allodynia

artículo científico publicado en 1995

Nucleolin-Mediated RNA Localization Regulates Neuron Growth and Cycling Cell Size

artículo científico publicado en 2016

Optical cuff for optogenetic control of the peripheral nervous system.

artículo científico publicado en 2017

Overexpression of the wild-type SPT1 subunit lowers desoxysphingolipid levels and rescues the phenotype of HSAN1

artículo científico publicado en 2009

Pain TRPs

artículo científico publicado en 2005

Pain and infection: pathogen detection by nociceptors.

artículo científico publicado en 2016

Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord.

artículo científico publicado en 2002

Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1.

artículo científico publicado en 2014

Periganglionic inflammation elicits a distally radiating pain hypersensitivity by promoting COX-2 induction in the dorsal root ganglion

artículo científico publicado en 2009

Peripheral axonal injury results in reduced mu opioid receptor pre- and post-synaptic action in the spinal cord

artículo científico publicado en 2005

Peripheral cell types contributing to the hyperalgesic action of nerve growth factor in inflammation

artículo científico publicado en 1996

Peripheral nerve injury alters excitatory synaptic transmission in lamina II of the rat dorsal horn

artículo científico publicado en 2003

Peripheral noxious stimulation induces phosphorylation of the NMDA receptor NR1 subunit at the PKC-dependent site, serine-896, in spinal cord dorsal horn neurons

artículo científico publicado en 2004

Permeation and block of TRPV1 channels by the cationic lidocaine derivative QX-314

artículo científico publicado en 2013

Persistent postsurgical pain: risk factors and prevention

artículo científico publicado en 2006

Personalized medicine and opioid analgesic prescribing for chronic pain: opportunities and challenges

artículo científico publicado en 2013

Phenotypic drug screen uncovers the metabolic GCH1/BH4 pathway as key regulator of EGFR/KRAS-mediated neuropathic pain and lung cancer

artículo científico publicado en 2022

Phenotyping the function of TRPV1-expressing sensory neurons by targeted axonal silencing

artículo científico publicado en 2013

Progressive tactile hypersensitivity after a peripheral nerve crush: non-noxious mechanical stimulus-induced neuropathic pain

artículo científico publicado en 2002

Prostaglandin E2 receptor EP4 contributes to inflammatory pain hypersensitivity.

artículo científico publicado en 2006

Publisher Correction: The metabolite BH4 controls T cell proliferation in autoimmunity and cancer

artículo científico publicado en 2019

Purkinje cells derived from TSC patients display hypoexcitability and synaptic deficits associated with reduced FMRP levels and reversed by rapamycin

artículo científico publicado en 2018

Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling

scientific article published on 20 November 2019

Reduced hyperalgesia in homozygous carriers of a GTP cyclohydrolase 1 haplotype

artículo científico publicado en 2008

Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway

artículo científico publicado en 2015

Reliable Screening for a Pain-Protective Haplotype in the GTP Cyclohydrolase 1 Gene (GCH1) Through the Use of 3 or Fewer Single Nucleotide Polymorphisms

article

Removal of GABAergic inhibition facilitates polysynaptic A fiber-mediated excitatory transmission to the superficial spinal dorsal horn

artículo científico publicado en 2003

Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury

artículo científico publicado en 2002

Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor

scientific journal article

Research design considerations for chronic pain prevention clinical trials: IMMPACT recommendations

artículo científico

Ro5-4864 promotes neonatal motor neuron survival and nerve regeneration in adult rats

artículo científico publicado en 2008

Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS

artículo científico publicado en 2015

Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS

artículo científico publicado en 2016

Role of the peripheral benzodiazepine receptor in sensory neuron regeneration

artículo científico publicado en 2005

Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain

artículo científico publicado en 2006

Selective up-regulation of the growth arrest DNA damage-inducible gene Gadd45 alpha in sensory and motor neurons after peripheral nerve injury

artículo científico publicado en 2003

Selectively targeting pain in the trigeminal system

artículo científico publicado en 2010

Sense and Immunity: Context-Dependent Neuro-Immune Interplay.

artículo científico publicado en 2017

Sensitivity and sensitisation in relation to pain severity in knee osteoarthritis: trait or state?

artículo científico publicado en 2013

Sepiapterin Reductase Inhibition Leading to Selective Reduction of Inflammatory Joint Pain in Mice and Increased Urinary Sepiapterin Levels in Humans and Mice

scientific article published on 28 November 2019

Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation.

artículo científico publicado en 2015

Soluble epoxide hydrolase limits mechanical hyperalgesia during inflammation

artículo científico publicado en 2011

Staphylococcus aureus produces pain through pore-forming toxins and neuronal TRPV1 that is silenced by QX-314.

artículo científico publicado en 2018

Substance P activates Mas-related G protein-coupled receptors to induce itch

artículo científico publicado en 2017

Synaptic plasticity and central sensitization: author reply

scientific article published on 01 August 2010

T-cell infiltration and signaling in the adult dorsal spinal cord is a major contributor to neuropathic pain-like hypersensitivity.

artículo científico publicado en 2009

TRPA1 contributes to cold hypersensitivity

scientific journal article

Tachykinin NK1 receptor antagonist RP67580 attenuates progressive hypersensitivity of flexor reflex during experimental inflammation in rats

artículo científico publicado en 1997

Targeting CYP2J to reduce paclitaxel-induced peripheral neuropathic pain.

scientific article published on 17 October 2016

Targeting of sodium channel blockers into nociceptors to produce long-duration analgesia: a systematic study and review ⬇️

artículo científico publicado el 1 de septiembre de 2011

The BMP coreceptor RGMb promotes while the endogenous BMP antagonist noggin reduces neurite outgrowth and peripheral nerve regeneration by modulating BMP signaling.

artículo científico publicado en 2011

The G2A receptor (GPR132) contributes to oxaliplatin-induced mechanical pain hypersensitivity

artículo científico publicado en 2017

The Role of Iron Regulation in Immunometabolism and Immune-Related Disease

scientific article published on 22 November 2019

The Stress-Induced Atf3-Gelsolin Cascade Underlies Dendritic Spine Deficits in Neuronal Models of Tuberous Sclerosis Complex

artículo científico publicado en 2015

The metabolite BH4 controls T cell proliferation in autoimmunity and cancer

artículo científico publicado en 2018

The neuropathic pain triad: neurons, immune cells and glia

artículo científico publicado en 2007

The pathophysiology of chronic pain--increased sensitivity to low threshold A beta-fibre inputs.

artículo científico publicado en 1994

The pattern of expression of the voltage-gated sodium channels Na(v)1.8 and Na(v)1.9 does not change in uninjured primary sensory neurons in experimental neuropathic pain models

artículo científico publicado en 2002

The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase.

artículo científico publicado en 2015

The transcription factor ATF-3 promotes neurite outgrowth

artículo científico publicado en 2006

The voltage-gated sodium channel Na(v)1.9 is an effector of peripheral inflammatory pain hypersensitivity.

artículo científico publicado en 2006

Therapeutic restoration of spinal inhibition via druggable enhancement of potassium-chloride cotransporter KCC2-mediated chloride extrusion in peripheral neuropathic pain

artículo científico publicado en 2014

Time-Resolved Fast Mammalian Behavior Reveals the Complexity of Protective Pain Responses

artículo científico publicado en 2017

Topoisomerase I inhibition and peripheral nerve injury induce DNA breaks and ATF3-associated axon regeneration in sensory neurons

artículo científico publicado en 2021

Touch and tactile neuropathic pain sensitivity are set by corticospinal projections

scientific article published in Nature

Toward a Mechanism-Based Approach to Pain Diagnosis

artículo científico

Transcriptional Reprogramming of Distinct Peripheral Sensory Neuron Subtypes after Axonal Injury

scientific article published on 14 August 2020

Transcriptional and posttranslational plasticity and the generation of inflammatory pain

artículo científico publicado en 1999

Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity.

artículo científico publicado en 2014

Transient receptor potential channels: targeting pain at the source

artículo científico publicado en 2009

TrpA1 regulates thermal nociception in Drosophila

artículo científico publicado en 2011

Two independent mouse lines carrying the Nav1.7-I228M gain-of-function variant display DRG neuron hyperexcitability but a minimal pain phenotype

artículo científico publicado en 2020

Understanding chronic inflammatory and neuropathic pain

artículo científico publicado en 2012

Unraveling the Plastic Peripheral Neuroimmune Interactome

scientific article published on 01 January 2020

Upregulation of the Voltage-Gated Sodium Channel 2 Subunit in Neuropathic Pain Models: Characterization of Expression in Injured and Non-Injured Primary Sensory Neurons

article

Utilization of an HSV-based amplicon vector encoding the axonal marker hPLAP to follow neurite outgrowth in cultured DRG neurons

artículo científico publicado en 2004

Vagal sensory neurons drive mucous cell metaplasia

artículo científico publicado en 2020

Zinc reduces the hyperalgesia and upregulation of NGF and IL-1 beta produced by peripheral inflammation in the rat

artículo científico publicado en 1996

p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia

artículo científico publicado en 2002

p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain.

artículo científico publicado en 2003

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