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Lista de obras de Martin R. Sprick

A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer

artículo científico publicado en 2015

Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell-of-origin

scientific article published on 15 October 2020

Apoptosis mediated by lentiviral TRAIL transfer involves transduction-dependent and -independent effects

artículo científico publicado en 2006

Biochemistry and function of the DISC

artículo científico publicado en 2001

Bortezomib sensitizes primary human astrocytoma cells of WHO grades I to IV for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis.

artículo científico publicado en 2007

Bortezomib sensitizes primary meningioma cells to TRAIL-induced apoptosis by enhancing formation of the death-inducing signaling complex.

artículo científico publicado en 2014

CD95 promotes metastatic spread via Sck in pancreatic ductal adenocarcinoma.

artículo científico publicado en 2015

CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma

artículo científico publicado en 2016

Cancer stem cells--old concepts, new insights.

artículo científico publicado en 2008

Caspase-10 Negatively Regulates Caspase-8-Mediated Cell Death, Switching the Response to CD95L in Favor of NF-κB Activation and Cell Survival

artículo científico publicado en 2017

Defined conditions for the isolation and expansion of basal prostate progenitor cells of mouse and human origin

artículo científico publicado en 2015

Determination of copper speciation in highway stormwater runoff using competitive ligand exchange - Adsorptive cathodic stripping voltammetry

artículo científico publicado en 2012

Development and characteristics of preclinical experimental models for the research of rare neuroendocrine bladder cancer

artículo científico

Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs.

artículo científico publicado en 2004

Expression and prognostic significance of cancer stem cell markers CD24 and CD44 in urothelial bladder cancer xenografts and patients undergoing radical cystectomy.

artículo científico publicado en 2014

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

artículo científico publicado en 2000

High prevalence of incidental and symptomatic venous thromboembolic events in patients with advanced pancreatic cancer under palliative chemotherapy: A retrospective cohort study.

artículo científico publicado en 2017

Identification and Validation of Novel Subtype-Specific Protein Biomarkers in Pancreatic Ductal Adenocarcinoma.

artículo científico publicado en 2016

Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay

artículo científico publicado en 2013

Identification of a tumor-reactive T-cell repertoire in the immune infiltrate of patients with resectable pancreatic ductal adenocarcinoma

artículo científico publicado en 2016

Impact of apoptotic circulating tumor cells (aCTC) in metastatic breast cancer.

artículo científico publicado en 2016

Label retaining cells in cancer--the dormant root of evil?

artículo científico

Martin Leverkus, 1965-2016.

artículo científico publicado en 2017

NF-kappaB inhibition reveals differential mechanisms of TNF versus TRAIL-induced apoptosis upstream or at the level of caspase-8 activation independent of cIAP2.

artículo científico publicado en 2007

Pancreatic Ductal Adenocarcinoma Subtyping Using the Biomarkers Hepatocyte Nuclear Factor-1A and Cytokeratin-81 Correlates with Outcome and Treatment Response

artículo científico publicado en 2017

Potential role of soluble TRAIL in epithelial injury in children with severe RSV infection.

artículo científico publicado en 2009

Proteasome Inhibition Results in TRAIL Sensitization of Primary Keratinocytes by Removing the Resistance-Mediating Block of Effector Caspase Maturation.

artículo científico publicado en 2003

Protein profile of basal prostate epithelial progenitor cells--stage-specific embryonal antigen 4 expressing cells have enhanced regenerative potential in vivo.

artículo científico publicado en 2016

Screening drug effects in patient-derived cancer cells links organoid responses to genome alterations.

artículo científico publicado en 2017

Serial enumeration of circulating tumor cells predicts treatment response and prognosis in metastatic breast cancer: a prospective study in 393 patients

artículo científico publicado en 2014

Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity.

artículo científico publicado en 2008

Suppression of cFLIP is sufficient to sensitize human melanoma cells to TRAIL- and CD95L-mediated apoptosis

scientific article published on 17 December 2007

Survival of pancreatic cancer cells lacking KRAS function.

artículo científico publicado en 2017

TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer-specific apoptosis within a therapeutic window.

artículo científico publicado en 2007

The impact of HER2 phenotype of circulating tumor cells in metastatic breast cancer: a retrospective study in 107 patients

artículo científico publicado en 2015

The influence of prostatic anatomy and neurotrophins on basal prostate epithelial progenitor cells

artículo científico publicado en 2015

The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death

artículo científico publicado en 2017

The sialyl-glycolipid stage-specific embryonic antigen 4 marks a subpopulation of chemotherapy-resistant breast cancer cells with mesenchymal features

artículo científico publicado en 2015

Therapy-resistant tumor microvascular endothelial cells contribute to treatment failure in glioblastoma multiforme.

artículo científico publicado en 2012

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

artículo científico publicado en 2010

cFLIPL inhibits tumor necrosis factor-related apoptosis-inducing ligand-mediated NF-kappaB activation at the death-inducing signaling complex in human keratinocytes

artículo científico publicado en 2004