Lista de obras - Nathalie Droin - Dominio Público Uruguay

A Recurrent Activating Missense Mutation in Waldenström Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances Proliferation

scientific article published on 24 April 2019

A constitutive BCL2 down-regulation aggravates the phenotype of PKD1-mutant-induced polycystic kidney disease.

artículo científico publicado en 2017

A miR-150/TET3 pathway regulates the generation of mouse and human non-classical monocyte subset

artículo científico publicado en 2018

A public T cell clonotype within a heterogeneous autoreactive repertoire is dominant in driving EAE.

artículo científico publicado en 2007

A role for caspases in the differentiation of erythroid cells and macrophages.

artículo científico publicado en 2007

A role for reactive oxygen species in JAK2 V617F myeloproliferative neoplasm progression.

artículo científico publicado en 2013

A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome

scientific article published on 01 July 2019

Accumulation of classical monocytes defines a subgroup of MDS that frequently evolves into CMML.

artículo científico publicado en 2017

Acquired TET2 mutation in one patient with familial platelet disorder with predisposition to AML led to the development of pre-leukaemic clone resulting in T2-ALL and AML-M0

artículo científico publicado en 2016

Acquired initiating mutations in early hematopoietic cells of CLL patients

artículo científico publicado en 2014

Activation-induced cell death in T cells

artículo científico publicado en 2003

Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia.

artículo científico publicado en 2009

Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells

artículo científico publicado en 2013

Author Correction: Genomic characterization of metastatic breast cancers

scientific article published on 01 August 2019

BCR-ABL delays apoptosis upstream of procaspase-3 activation

artículo científico publicado en 1998

Biallelic inactivation of the retinoblastoma gene results in transformation of chronic myelomonocytic leukemia to a blastic plasmacytoid dendritic cell neoplasm: shared clonal origins of two aggressive neoplasms

article

Biology and prognostic impact of clonal plasmacytoid dendritic cells in chronic myelomonocytic leukemia

scientific article published on 20 March 2019

CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death.

artículo científico publicado en 2005

Cancer cell sensitization to fas-mediated apoptosis by sodium butyrate

artículo científico publicado en 1998

Caspase-induced proteolysis of the cyclin-dependent kinase inhibitor p27Kip1 mediates its anti-apoptotic activity.

artículo científico publicado en 1999

Characteristic repartition of monocyte subsets as a diagnostic signature of chronic myelomonocytic leukemia

artículo científico publicado en 2015

Circulating Cell-Free Tumor DNA Analysis of 50 Genes by Next-Generation Sequencing in the Prospective MOSCATO Trial

scientific article published on 12 January 2016

Circulating Immature Granulocytes With T-Cell Killing Functions Predict Sepsis Deterioration*

Clinical, molecular, and prognostic correlates of number, type, and functional localization of TET2 mutations in chronic myelomonocytic leukemia (CMML)-a study of 1084 patients

scientific article published on 13 December 2019

Clonal architecture of chronic myelomonocytic leukemias

artículo científico publicado en 2013

Cohen syndrome is associated with major glycosylation defects

artículo científico publicado en 2013

Colony-stimulating factor-1-induced oscillations in phosphatidylinositol-3 kinase/AKT are required for caspase activation in monocytes undergoing differentiation into macrophages

artículo científico publicado en 2009

Concerted functions of Gab1 and Shp2 in liver regeneration and hepatoprotection

artículo científico publicado en 2006

Congenital neutropenia with retinopathy, a new phenotype without intellectual deficiency or obesity secondary to VPS13B mutations.

artículo científico publicado en 2013

Constitutive activation of RAS/MAPK pathway cooperates with trisomy 21 and is therapeutically exploitable in Down syndrome B-cell leukemia

scientific article published on 27 March 2020

DNA damage and S phase-dependent E2F1 stabilization requires the cIAP1 E3-ubiquitin ligase and is associated with K63-poly-ubiquitination on lysine 161/164 residues.

artículo científico publicado en 2017

DNMT3A(R882H) mutant and Tet2 inactivation cooperate in the deregulation of DNA methylation control to induce lymphoid malignancies in mice

artículo científico publicado en 2016

Death in paradise

artículo científico publicado en 2002

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

artículo científico publicado en 2004

Downregulation of TREM-like transcript-1 and collagen receptor α2 subunit, two novel RUNX1-targets, contributes to platelet dysfunction in familial platelet disorder with predisposition to acute myelogenous leukemia

artículo científico publicado en 2018

Dual regulation of SPI1/PU.1 transcription factor by heat shock factor 1 (HSF1) during macrophage differentiation of monocytes

artículo científico publicado en 2014

Dynamic gene regulation by nuclear colony-stimulating factor 1 receptor in human monocytes and macrophages

article

Dynamic programming of CD8+ T lymphocyte responses

article

Dynamic regulation of FoxP3 expression controls the balance between CD4+ T cell activation and cell death

artículo científico publicado en 2005

E2F1 binds to the peptide-binding groove within the BIR3 domain of cIAP1 and requires cIAP1 for chromatin binding

artículo científico publicado en 2018

ETO2-GLIS2 Hijacks Transcriptional Complexes to Drive Cellular Identity and Self-Renewal in Pediatric Acute Megakaryoblastic Leukemia.

artículo científico publicado en 2017

Editorial: CSF1R, CSF-1, and IL-34, a "menage a trois" conserved across vertebrates.

artículo científico publicado en 2010

Egr family members regulate nonlymphoid expression of Fas ligand, TRAIL, and tumor necrosis factor during immune responses

artículo científico publicado en 2003

Engraftment of chronic myelomonocytic leukemia cells in immunocompromised mice supports disease dependency on cytokines

artículo científico publicado en 2017

Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice

artículo científico publicado en 2006

Eosinophil-rich tissue infiltrates in chronic myelomonocytic leukemia patients.

artículo científico publicado en 2017

FAS(CD95) ligand expression by tumor cell variants can be unrelated to their capacity to induce tolerance or immune rejection

artículo científico publicado en 1999

Familial predisposition to TP53/complex karyotype MDS and leukemia in DNA repair-deficient xeroderma pigmentosum

scientific article published on 26 March 2019

Fine-tuning nucleophosmin in macrophage differentiation and activation.

artículo científico publicado en 2011

Genetic characterization of B-cell prolymphocytic leukemia: a prognostic model involving MYC and TP53

artículo científico publicado en 2019

Genomic characterization of metastatic breast cancers

artículo científico publicado en 2019

Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies

artículo científico publicado en 2015

Heterogeneity of molecular markers in chronic myelomonocytic leukemia: a disease associated with several gene alterations.

artículo científico publicado en 2012

High prevalence of myeloid neoplasms in adults with non-Langerhans cell histiocytosis.

artículo científico publicado en 2017

Identification of a caspase-2 isoform that behaves as an endogenous inhibitor of the caspase cascade

artículo científico publicado en 2000

Integrative analysis of dysregulated microRNAs and mRNAs in multiple recurrent synchronized renal tumors from patients with von Hippel-Lindau disease

scientific article published on 19 July 2018

Involvement of caspase-2 long isoform in Fas-mediated cell death of human leukemic cells.

artículo científico publicado en 2001

Leukemic cell xenograft in zebrafish embryo for investigating drug efficacy.

artículo científico publicado en 2011

MYH10 protein expression in platelets as a biomarker of RUNX1 and FLI1 alterations.

artículo científico publicado en 2012

Macrophage migration inhibitory factor is overproduced through EGR1 in TET2<sup>low</sup> resting monocytes

artículo científico publicado en 2022

MiR-142-3p et leucémogenèse

artículo científico publicado en 2013

Mice Lacking bi-1 Gene Show Accelerated Liver Regeneration

article

Molecular predictors of response to decitabine in advanced chronic myelomonocytic leukemia: a phase 2 trial.

artículo científico publicado en 2011

Multilayer intraclonal heterogeneity in chronic myelomonocytic leukemia

scientific article published on 02 May 2019

Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents

artículo científico publicado en 2016

Mutation of the colony-stimulating factor-3 receptor gene is a rare event with poor prognosis in chronic myelomonocytic leukemia.

artículo científico publicado en 2013

NF-kappaB inhibits T-cell activation-induced, p73-dependent cell death by induction of MDM2

artículo científico publicado en 2010

Next-generation sequencing discriminates myelodysplastic/myeloproliferative neoplasms from paraneoplastic leukemoid reaction in cancer patients with hyperleukocytosis.

artículo científico publicado en 2017

Non-apoptotic functions of caspases in myeloid cell differentiation.

artículo científico publicado en 2017

Nonlymphoid Fas ligand in peptide-induced peripheral lymphocyte deletion

artículo científico publicado en 2002

Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene-Driven Myeloid Leukemia

scientific article published on 29 October 2019

Outcome and molecular landscape of patients with PIK3CA-mutated metastatic breast cancer

artículo científico publicado en 2020

Positive and negative regulation of apoptotic pathways by cytotoxic agents in hematological malignancies.

artículo científico publicado en 2000

Positive feedback regulation of PLCgamma1/Ca(2+) signaling by PKCtheta in restimulated T cells via a Tec kinase-dependent pathway.

artículo científico publicado en 2004

Presence of a transcriptionally active glucocorticoid receptor alpha in lens epithelial cells

artículo científico publicado en 2003

Presence of atypical thrombopoietin receptor (MPL) mutations in triple-negative essential thrombocythemia patients

artículo científico publicado en 2015

Prognostic Role of Gene Mutations in Chronic Myelomonocytic Leukemia Patients Treated With Hypomethylating Agents.

artículo científico publicado en 2018

Prognostic score including gene mutations in chronic myelomonocytic leukemia.

artículo científico publicado en 2013

Prognostic value of monocyte subset distribution in chronic myelomonocytic leukemia: results of a multicenter study

artículo científico publicado en 2020

Proteases, proteolysis, and apoptosis

artículo científico publicado el 1 de marzo de 1998

Protein kinase C-theta is an early survival factor required for differentiation of effector CD8+ T cells.

artículo científico publicado en 2005

RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis

artículo científico publicado en 2021

Retroperitoneal fibrosis as extramedullary hematopoiesis of a chronic myelomonocytic leukemia

artículo científico publicado en 2018

Role of Bcl-2 family members in immunity and disease

artículo científico publicado en 2004

SETBP1 mutations in 658 patients with myelodysplastic syndromes, chronic myelomonocytic leukemia and secondary acute myeloid leukemias.

artículo científico publicado en 2013

Serpin B1 defect and increased apoptosis of neutrophils in Cohen syndrome neutropenia

artículo científico publicado en 2019

Specific molecular signatures predict decitabine response in chronic myelomonocytic leukemia.

artículo científico publicado en 2015

TET2 deficiency causes germinal center hyperplasia, impairs plasma cell differentiation and promotes B-cell lymphomagenesis

artículo científico publicado en 2018

TET2 deficiency inhibits mesoderm and hematopoietic differentiation in human embryonic stem cells.

artículo científico publicado en 2014

TIF1γ: a tumor suppressor gene in chronic myelomonocytic leukemia

artículo científico publicado en 2011

Targeting apoptosis proteins in hematological malignancies.

artículo científico publicado en 2011

The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML

artículo científico publicado en 2015

The emerging specificities of interleukin-34.

artículo científico publicado en 2014

The inhibitory HVEM-BTLA pathway counter regulates lymphotoxin receptor signaling to achieve homeostasis of dendritic cells

artículo científico publicado en 2008

The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways

artículo científico publicado en 2002

The role of ARK in stress-induced apoptosis in Drosophila cells

artículo científico publicado en 2002

Tumor cells can escape DNA-damaging cisplatin through DNA endoreduplication and reversible polyploidy

artículo científico publicado en 2008

Tumor necrosis factor alpha up-regulates non-lymphoid Fas-ligand following superantigen-induced peripheral lymphocyte activation

artículo científico publicado en 2002

Upregulation of CASP genes in human tumor cells undergoing etoposide-induced apoptosis ⬇️

artículo científico publicado el 4 de junio de 1998

Use of the 46/1 haplotype to model JAK2(V617F) clonal architecture in PV patients: clonal evolution and impact of IFNα treatment.

artículo científico publicado en 2013

Various functions of caspases in hematopoiesis.

artículo científico publicado en 2009

[Dynamic role of nuclear CSF1R in the monocytic lineage]

scientific article published on 01 December 2019

p27Kip1 induces drug resistance by preventing apoptosis upstream of cytochrome c release and procaspase-3 activation in leukemic cells.

artículo científico publicado en 1999

Lista de obras de Nathalie Droin

A Recurrent Activating Missense Mutation in Waldenström Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances Proliferation

A constitutive BCL2 down-regulation aggravates the phenotype of PKD1-mutant-induced polycystic kidney disease.

A miR-150/TET3 pathway regulates the generation of mouse and human non-classical monocyte subset

A public T cell clonotype within a heterogeneous autoreactive repertoire is dominant in driving EAE.

A role for caspases in the differentiation of erythroid cells and macrophages.

A role for reactive oxygen species in JAK2 V617F myeloproliferative neoplasm progression.

A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome

Accumulation of classical monocytes defines a subgroup of MDS that frequently evolves into CMML.

Acquired TET2 mutation in one patient with familial platelet disorder with predisposition to AML led to the development of pre-leukaemic clone resulting in T2-ALL and AML-M0

Acquired initiating mutations in early hematopoietic cells of CLL patients

Activation-induced cell death in T cells

Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia.

Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells

Author Correction: Genomic characterization of metastatic breast cancers

BCR-ABL delays apoptosis upstream of procaspase-3 activation

Biallelic inactivation of the retinoblastoma gene results in transformation of chronic myelomonocytic leukemia to a blastic plasmacytoid dendritic cell neoplasm: shared clonal origins of two aggressive neoplasms

Biology and prognostic impact of clonal plasmacytoid dendritic cells in chronic myelomonocytic leukemia

CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death.

Cancer cell sensitization to fas-mediated apoptosis by sodium butyrate

Caspase-induced proteolysis of the cyclin-dependent kinase inhibitor p27Kip1 mediates its anti-apoptotic activity.

Characteristic repartition of monocyte subsets as a diagnostic signature of chronic myelomonocytic leukemia

Circulating Cell-Free Tumor DNA Analysis of 50 Genes by Next-Generation Sequencing in the Prospective MOSCATO Trial

Circulating Immature Granulocytes With T-Cell Killing Functions Predict Sepsis Deterioration*

Clinical, molecular, and prognostic correlates of number, type, and functional localization of TET2 mutations in chronic myelomonocytic leukemia (CMML)-a study of 1084 patients

Clonal architecture of chronic myelomonocytic leukemias

Cohen syndrome is associated with major glycosylation defects

Colony-stimulating factor-1-induced oscillations in phosphatidylinositol-3 kinase/AKT are required for caspase activation in monocytes undergoing differentiation into macrophages

Concerted functions of Gab1 and Shp2 in liver regeneration and hepatoprotection

Congenital neutropenia with retinopathy, a new phenotype without intellectual deficiency or obesity secondary to VPS13B mutations.

Constitutive activation of RAS/MAPK pathway cooperates with trisomy 21 and is therapeutically exploitable in Down syndrome B-cell leukemia

DNA damage and S phase-dependent E2F1 stabilization requires the cIAP1 E3-ubiquitin ligase and is associated with K63-poly-ubiquitination on lysine 161/164 residues.

DNMT3A(R882H) mutant and Tet2 inactivation cooperate in the deregulation of DNA methylation control to induce lymphoid malignancies in mice

Death in paradise

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

Downregulation of TREM-like transcript-1 and collagen receptor α2 subunit, two novel RUNX1-targets, contributes to platelet dysfunction in familial platelet disorder with predisposition to acute myelogenous leukemia

Dual regulation of SPI1/PU.1 transcription factor by heat shock factor 1 (HSF1) during macrophage differentiation of monocytes

Dynamic gene regulation by nuclear colony-stimulating factor 1 receptor in human monocytes and macrophages

Dynamic programming of CD8+ T lymphocyte responses

Dynamic regulation of FoxP3 expression controls the balance between CD4+ T cell activation and cell death

E2F1 binds to the peptide-binding groove within the BIR3 domain of cIAP1 and requires cIAP1 for chromatin binding

ETO2-GLIS2 Hijacks Transcriptional Complexes to Drive Cellular Identity and Self-Renewal in Pediatric Acute Megakaryoblastic Leukemia.

Editorial: CSF1R, CSF-1, and IL-34, a "menage a trois" conserved across vertebrates.

Egr family members regulate nonlymphoid expression of Fas ligand, TRAIL, and tumor necrosis factor during immune responses

Engraftment of chronic myelomonocytic leukemia cells in immunocompromised mice supports disease dependency on cytokines

Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice

Eosinophil-rich tissue infiltrates in chronic myelomonocytic leukemia patients.

FAS(CD95) ligand expression by tumor cell variants can be unrelated to their capacity to induce tolerance or immune rejection

Familial predisposition to TP53/complex karyotype MDS and leukemia in DNA repair-deficient xeroderma pigmentosum

Fine-tuning nucleophosmin in macrophage differentiation and activation.

Genetic characterization of B-cell prolymphocytic leukemia: a prognostic model involving MYC and TP53

Genomic characterization of metastatic breast cancers

Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies

Heterogeneity of molecular markers in chronic myelomonocytic leukemia: a disease associated with several gene alterations.

High prevalence of myeloid neoplasms in adults with non-Langerhans cell histiocytosis.

Identification of a caspase-2 isoform that behaves as an endogenous inhibitor of the caspase cascade

Integrative analysis of dysregulated microRNAs and mRNAs in multiple recurrent synchronized renal tumors from patients with von Hippel-Lindau disease

Involvement of caspase-2 long isoform in Fas-mediated cell death of human leukemic cells.

Leukemic cell xenograft in zebrafish embryo for investigating drug efficacy.

MYH10 protein expression in platelets as a biomarker of RUNX1 and FLI1 alterations.

Macrophage migration inhibitory factor is overproduced through EGR1 in TET2<sup>low</sup> resting monocytes

MiR-142-3p et leucémogenèse

Mice Lacking bi-1 Gene Show Accelerated Liver Regeneration

Molecular predictors of response to decitabine in advanced chronic myelomonocytic leukemia: a phase 2 trial.

Multilayer intraclonal heterogeneity in chronic myelomonocytic leukemia

Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents

Mutation of the colony-stimulating factor-3 receptor gene is a rare event with poor prognosis in chronic myelomonocytic leukemia.

NF-kappaB inhibits T-cell activation-induced, p73-dependent cell death by induction of MDM2

Next-generation sequencing discriminates myelodysplastic/myeloproliferative neoplasms from paraneoplastic leukemoid reaction in cancer patients with hyperleukocytosis.

Non-apoptotic functions of caspases in myeloid cell differentiation.

Nonlymphoid Fas ligand in peptide-induced peripheral lymphocyte deletion

Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene-Driven Myeloid Leukemia

Outcome and molecular landscape of patients with PIK3CA-mutated metastatic breast cancer

Positive and negative regulation of apoptotic pathways by cytotoxic agents in hematological malignancies.

Positive feedback regulation of PLCgamma1/Ca(2+) signaling by PKCtheta in restimulated T cells via a Tec kinase-dependent pathway.

Presence of a transcriptionally active glucocorticoid receptor alpha in lens epithelial cells

Presence of atypical thrombopoietin receptor (MPL) mutations in triple-negative essential thrombocythemia patients

Prognostic Role of Gene Mutations in Chronic Myelomonocytic Leukemia Patients Treated With Hypomethylating Agents.

Prognostic score including gene mutations in chronic myelomonocytic leukemia.

Prognostic value of monocyte subset distribution in chronic myelomonocytic leukemia: results of a multicenter study