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Lista de obras de Paulo Paixão

A Mechanistic Physiologically-Based Biopharmaceutics Modeling (PBBM) Approach to Assess the In Vivo Performance of an Orally Administered Drug Product: From IVIVC to IVIVP

scientific article published on 17 January 2020

An alternative single dose parameter to avoid the need for steady-state studies on oral extended-release drug products ⬇️

artículo científico publicado el 15 de noviembre de 2011

Evaluation of dissolution profile similarity - Comparison between the f2, the multivariate statistical distance and the f2 bootstrapping methods

artículo científico publicado en 2016

Formulation predictive dissolution (fPD) testing to advance oral drug product development: An introduction to the US FDA funded '21st Century BA/BE' project

artículo científico publicado en 2018

Functionalization of PLGA Nanoparticles with 1,3-β-glucan Enhances the Intracellular Pharmacokinetics of Rifampicin in Macrophages.

artículo científico publicado en 2018

Gastric emptying and intestinal appearance of nonabsorbable drugs phenol red and paromomycin in human subjects: A multi-compartment stomach approach

artículo científico publicado en 2018

Implementing the Biopharmaceutics Classification System in Drug Development: Reconciling Similarities, Differences, and Shared Challenges in the EMA and US-FDA-Recommended Approaches

artículo científico publicado en 2016

Implementing the additional strength biowaiver for generics: EMA recommended approaches and challenges for a US-FDA submission

artículo científico publicado en 2017

In Vitro Antimicrobial Activity of Isopimarane-Type Diterpenoids

scientific article published on 16 September 2020

Linking the Gastrointestinal Behavior of Ibuprofen with The Systemic Exposure Between and Within Humans - Part 1: Fasted State

artículo científico publicado en 2018

Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans-Part 2: Fed State

artículo científico publicado en 2018

Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for in Vivo Dissolution and Absorption of Ionizable Drugs

artículo científico publicado en 2017

Measuring the Impact of Gastrointestinal Variables on the Systemic Outcome of Two Suspensions of Posaconazole by a PBPK Model

scientific article published on 29 March 2018

Physiologically-Based Pharmacokinetic Model on the Oral Drug Absorption in Roux-en-Y Gastric Bypass Bariatric Patients: Amoxicillin Tablet and Suspension

scientific article published on 18 November 2019

Population Approach to Efavirenz Therapy

artículo científico publicado en 2017

Prediction of drug distribution in rat and humans using an artificial neural networks ensemble and a PBPK model

artículo científico publicado en 2014

Prediction of drug distribution within blood.

artículo científico publicado en 2008

Prediction of the human oral bioavailability by using in vitro and in silico drug related parameters in a physiologically based absorption model.

artículo científico publicado en 2012

Prediction of the in vitro intrinsic clearance determined in suspensions of human hepatocytes by using artificial neural networks

artículo científico publicado en 2010

Prediction of the in vitro permeability determined in Caco-2 cells by using artificial neural networks

artículo científico publicado en 2010

Reduced bioavailability of oral amoxicillin tablets compared to suspensions in Roux-en-Y gastric bypass bariatric subjects

scientific article published on 12 July 2019

Simple method for determination of paraquat in plasma and serum of human patients by high-performance liquid chromatography.

artículo científico publicado en 2002

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