Lista de obras - Eva Szegezdi - Dominio Público Uruguay

An added dimension to tumour TRAIL sensitivity

artículo científico publicado en 2015

An unfractionated fucoidan from Ascophyllum nodosum: extraction, characterization, and apoptotic effects in vitro.

artículo científico publicado en 2011

Apoptosis-linked in vivo regulation of the tissue transglutaminase gene promoter

scientific article published on 01 December 2000

Aspartic Aminopeptidase Is a Novel Biomarker of Aggressive Chronic Lymphocytic Leukemia

scientific article published on 12 July 2020

BCL-2 modulates the unfolded protein response by enhancing splicing of X-box binding protein-1.

artículo científico publicado en 2015

Bcl-2 family on guard at the ER.

artículo científico publicado en 2009

CD95-mediated alteration in Hsp70 levels is dependent on protein stabilization.

artículo científico publicado en 2005

Caspase-12 and ER-stress-mediated apoptosis: the story so far.

artículo científico publicado en 2003

Cell death in HIV pathogenesis and its modulation by retinoids.

artículo científico publicado en 2001

Cell-cell interactome of the hematopoietic niche and its changes in acute myeloid leukemia

scientific article published in 2023

Clearance of apoptotic thymocytes is decreased by inhibitors of eicosanoid synthesis

artículo científico publicado en 1999

Co-acting gene networks predict TRAIL responsiveness of tumour cells with high accuracy.

artículo científico publicado en 2014

Correlation between potassium channel expression and sensitivity to drug-induced cell death in tumor cell lines

artículo científico publicado en 2014

Cytokine-induced beta-cell apoptosis is NO-dependent, mitochondria-mediated and inhibited by BCL-XL.

artículo científico publicado en 2007

DR4-selective tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) variants obtained by structure-based design

artículo científico publicado en 2008

Decorated macrocycles via ring-closing double-reductive amination. identification of an apoptosis inducer of leukemic cells that at least partially antagonizes a 5-HT2 receptor.

artículo científico publicado en 2015

Decoy receptors block TRAIL sensitivity at a supracellular level: the role of stromal cells in controlling tumour TRAIL sensitivity.

artículo científico publicado en 2015

Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor

artículo científico publicado en 2006

Dexamethasone inhibits apoptosis in C6 glioma cells through increased expression of Bcl-XL.

artículo científico publicado en 2006

Differential activation of JNK1 isoforms by TRAIL receptors modulate apoptosis of colon cancer cell lines.

artículo científico publicado en 2009

ER stress contributes to ischemia-induced cardiomyocyte apoptosis

scientific journal article

Early growth response-1 is a regulator of DR5-induced apoptosis in colon cancer cells.

artículo científico publicado en 2010

Enhancement of antitumor properties of rhTRAIL by affinity increase toward its death receptors.

artículo científico publicado en 2009

Generation of Tumour-stroma Minispheroids for Drug Efficacy Testing

publication published on 05 January 2017

Guiding the Killer and Bringing in Accomplices: Bispecific Antibody Treatment for Malignant Melanoma

artículo científico publicado en 2016

Hsp27 inhibits 6-hydroxydopamine-induced cytochrome c release and apoptosis in PC12 cells

artículo científico publicado en 2005

Hypoxia and ischemia induce nuclear condensation and caspase activation in cardiomyocytes.

artículo científico publicado en 2003

Identification of an inhibitor of caspase activation from heart extracts; ATP blocks apoptosome formation

artículo científico publicado en 2007

Is there a role for nuclear factor kappaB in tumor necrosis factor-related apoptosis-inducing ligand resistance?

artículo científico publicado en 2009

Kinetics in Signal Transduction Pathways Involving Promiscuous Oligomerizing Receptors Can Be Determined by Receptor Specificity: Apoptosis Induction by TRAIL ⬇️

artículo científico publicado el 2 de enero de 2012

Ligation of retinoic acid receptor alpha regulates negative selection of thymocytes by inhibiting both DNA binding of nur77 and synthesis of bim.

artículo científico publicado en 2003

Mechanisms of ER Stress-Mediated Mitochondrial Membrane Permeabilization

artículo científico publicado en 2010

Metabolic flexibility permits mesenchymal stem cell survival in an ischemic environment.

artículo científico publicado en 2008

N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death

artículo científico publicado en 2017

NOXA contributes to the sensitivity of PERK-deficient cells to ER stress.

artículo científico publicado en 2012

Nerve growth factor blocks thapsigargin-induced apoptosis at the level of the mitochondrion via regulation of Bim

scientific journal article

Rapid and efficient cancer cell killing mediated by high-affinity death receptor homotrimerizing TRAIL variants.

artículo científico publicado en 2010

Recreating complex pathophysiologies in vitro with extracellular matrix surrogates for anticancer therapeutics screening.

artículo científico publicado en 2016

Recreating the Bone Marrow Microenvironment to Model Leukemic Stem Cell Quiescence

artículo científico publicado en 2021

Repression of Mcl-1 expression by the CDC7/CDK9 inhibitor PHA-767491 overcomes bone marrow stroma-mediated drug resistance in AML

artículo científico publicado en 2018

Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways ⬇️

artículo científico publicado el 4 de julio de 2013

Retinoid receptor-activating ligands are produced within the mouse thymus during postnatal development.

artículo científico publicado en 2008

Stem cells are resistant to TRAIL receptor-mediated apoptosis.

artículo científico publicado en 2009

Structural determinants of DISC function: New insights into death receptor-mediated apoptosis signalling ⬇️

artículo científico publicado el 8 de julio de 2013

Synthetic constrained peptide selectively binds and antagonizes death receptor 5.

artículo científico publicado en 2010

TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress

artículo científico publicado en 2016

TRAIL receptor signalling and modulation: Are we on the right TRAIL?

artículo científico publicado en 2008

TRAIL sensitisation by arsenic trioxide is caspase-8 dependent and involves modulation of death receptor components and Akt.

artículo científico publicado en 2006

Targeting AML through DR4 with a novel variant of rhTRAIL

artículo científico publicado en 2011

Targeting TRAIL towards the clinic.

artículo científico publicado en 2011

The BH3-mimetic ABT-737 effectively kills acute myeloid leukemia initiating cells

artículo científico publicado en 2014

The Janus Face of Death Receptor Signaling during Tumor Immunoediting

artículo científico publicado en 2016

The Proteasome Inhibitor Bortezomib Sensitizes AML with Myelomonocytic Differentiation to TRAIL Mediated Apoptosis.

artículo científico publicado en 2011

The mitochondrial death pathway: a promising therapeutic target in diseases

artículo científico publicado en 2009

The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL‑induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells

artículo científico publicado en 2016

Theranostic drug test incorporating the bone-marrow microenvironment can predict the clinical response of acute myeloid leukaemia to chemotherapy

artículo científico publicado en 2020

Three-dimensional ex vivo co-culture models of the leukaemic bone marrow niche for functional drug testing

artículo científico publicado en 2016

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Lista de obras de Eva Szegezdi

An added dimension to tumour TRAIL sensitivity

An unfractionated fucoidan from Ascophyllum nodosum: extraction, characterization, and apoptotic effects in vitro.

Apoptosis-linked in vivo regulation of the tissue transglutaminase gene promoter

Aspartic Aminopeptidase Is a Novel Biomarker of Aggressive Chronic Lymphocytic Leukemia

BCL-2 modulates the unfolded protein response by enhancing splicing of X-box binding protein-1.

Bcl-2 family on guard at the ER.

CD95-mediated alteration in Hsp70 levels is dependent on protein stabilization.

Caspase-12 and ER-stress-mediated apoptosis: the story so far.

Cell death in HIV pathogenesis and its modulation by retinoids.

Cell-cell interactome of the hematopoietic niche and its changes in acute myeloid leukemia

Clearance of apoptotic thymocytes is decreased by inhibitors of eicosanoid synthesis

Co-acting gene networks predict TRAIL responsiveness of tumour cells with high accuracy.

Correlation between potassium channel expression and sensitivity to drug-induced cell death in tumor cell lines

Cytokine-induced beta-cell apoptosis is NO-dependent, mitochondria-mediated and inhibited by BCL-XL.

DR4-selective tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) variants obtained by structure-based design

Decorated macrocycles via ring-closing double-reductive amination. identification of an apoptosis inducer of leukemic cells that at least partially antagonizes a 5-HT2 receptor.

Decoy receptors block TRAIL sensitivity at a supracellular level: the role of stromal cells in controlling tumour TRAIL sensitivity.

Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor

Dexamethasone inhibits apoptosis in C6 glioma cells through increased expression of Bcl-XL.

Differential activation of JNK1 isoforms by TRAIL receptors modulate apoptosis of colon cancer cell lines.

ER stress contributes to ischemia-induced cardiomyocyte apoptosis

Early growth response-1 is a regulator of DR5-induced apoptosis in colon cancer cells.

Enhancement of antitumor properties of rhTRAIL by affinity increase toward its death receptors.

Generation of Tumour-stroma Minispheroids for Drug Efficacy Testing

Guiding the Killer and Bringing in Accomplices: Bispecific Antibody Treatment for Malignant Melanoma

Hsp27 inhibits 6-hydroxydopamine-induced cytochrome c release and apoptosis in PC12 cells

Hypoxia and ischemia induce nuclear condensation and caspase activation in cardiomyocytes.

Identification of an inhibitor of caspase activation from heart extracts; ATP blocks apoptosome formation

Is there a role for nuclear factor kappaB in tumor necrosis factor-related apoptosis-inducing ligand resistance?

Kinetics in Signal Transduction Pathways Involving Promiscuous Oligomerizing Receptors Can Be Determined by Receptor Specificity: Apoptosis Induction by TRAIL ⬇️

Ligation of retinoic acid receptor alpha regulates negative selection of thymocytes by inhibiting both DNA binding of nur77 and synthesis of bim.

Mechanisms of ER Stress-Mediated Mitochondrial Membrane Permeabilization

Metabolic flexibility permits mesenchymal stem cell survival in an ischemic environment.

N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death

NOXA contributes to the sensitivity of PERK-deficient cells to ER stress.

Nerve growth factor blocks thapsigargin-induced apoptosis at the level of the mitochondrion via regulation of Bim

Rapid and efficient cancer cell killing mediated by high-affinity death receptor homotrimerizing TRAIL variants.

Recreating complex pathophysiologies in vitro with extracellular matrix surrogates for anticancer therapeutics screening.

Recreating the Bone Marrow Microenvironment to Model Leukemic Stem Cell Quiescence

Repression of Mcl-1 expression by the CDC7/CDK9 inhibitor PHA-767491 overcomes bone marrow stroma-mediated drug resistance in AML

Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways ⬇️

Retinoid receptor-activating ligands are produced within the mouse thymus during postnatal development.

Stem cells are resistant to TRAIL receptor-mediated apoptosis.

Structural determinants of DISC function: New insights into death receptor-mediated apoptosis signalling ⬇️

Synthetic constrained peptide selectively binds and antagonizes death receptor 5.

TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress

TRAIL receptor signalling and modulation: Are we on the right TRAIL?

TRAIL sensitisation by arsenic trioxide is caspase-8 dependent and involves modulation of death receptor components and Akt.

Targeting AML through DR4 with a novel variant of rhTRAIL

Targeting TRAIL towards the clinic.

The BH3-mimetic ABT-737 effectively kills acute myeloid leukemia initiating cells

The Janus Face of Death Receptor Signaling during Tumor Immunoediting

The Proteasome Inhibitor Bortezomib Sensitizes AML with Myelomonocytic Differentiation to TRAIL Mediated Apoptosis.

The mitochondrial death pathway: a promising therapeutic target in diseases

The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL‑induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells

Theranostic drug test incorporating the bone-marrow microenvironment can predict the clinical response of acute myeloid leukaemia to chemotherapy

Three-dimensional ex vivo co-culture models of the leukaemic bone marrow niche for functional drug testing

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)