Lista de obras - Stefan Pusch - Dominio Público Uruguay

A cell-based MAPK reporter assay reveals synergistic MAPK pathway activity suppression by MAPK inhibitor combination in BRAF-driven pediatric low-grade glioma cells

artículo científico publicado en 2020

A general G1/S-phase cell-cycle control module in the flowering plant Arabidopsis thaliana

artículo científico publicado en 2012

A vaccine targeting mutant IDH1 induces antitumour immunity

artículo científico publicado en 2014

Analysis of the subcellular localization, function, and proteolytic control of the Arabidopsis cyclin-dependent kinase inhibitor ICK1/KRP1.

artículo científico publicado en 2006

Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody

artículo científico publicado en 2011

Bimolecular-Fluorescence Complementation Assay to Monitor Kinase–Substrate Interactions In Vivo ⬇️

artículo científico publicado el 1 de enero de 2011

Brain tumour cells interconnect to a functional and resistant network

artículo científico publicado en 2015

CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas

artículo científico publicado en 2012

CIC protein instability contributes to tumorigenesis in glioblastoma

artículo científico publicado en 2019

Characterization of the epithelial membrane protein 3 interaction network reveals a potential functional link to mitogenic signal transduction regulation

scientific article published on 20 January 2019

Chromosome 8p tumor suppressor genes SH2D4A and SORBS3 cooperate to inhibit interleukin-6 signaling in hepatocellular carcinoma

artículo científico publicado en 2016

Control of cell proliferation, organ growth, and DNA damage response operate independently of dephosphorylation of the Arabidopsis Cdk1 homolog CDKA;1.

artículo científico publicado en 2009

D-2-Hydroxyglutarate producing neo-enzymatic activity inversely correlates with frequency of the type of isocitrate dehydrogenase 1 mutations found in glioma

artículo científico publicado en 2014

Design, synthesis and biological activity of 3-pyrazine-2-yl-oxazolidin-2-ones as novel, potent and selective inhibitors of mutant isocitrate dehydrogenase 1.

artículo científico publicado en 2017

Detection of 2-hydroxyglutarate in formalin-fixed paraffin-embedded glioma specimens by gas chromatography/mass spectrometry

artículo científico

Glioma IDH1 mutation patterns off the beaten track.

artículo científico publicado en 2011

IDH2 Mutations Define a Unique Subtype of Breast Cancer with Altered Nuclear Polarity

artículo científico publicado en 2016

Identification of a Prognostic Hypoxia-Associated Gene Set in IDH-Mutant Glioma

article

Identification of a novel inactivating mutation in Isocitrate Dehydrogenase 1 (IDH1-R314C) in a high grade astrocytoma.

artículo científico publicado en 2016

Identification of kinase substrates by bimolecular complementation assays ⬇️

artículo científico publicado el 10 de enero de 2012

Identification of novel allosteric inhibitors of mutant isocitrate dehydrogenase 1 by cross docking-based virtual screening.

artículo científico publicado en 2017

Immunohistochemical testing of BRAF V600E status in 1,120 tumor tissue samples of patients with brain metastases

artículo científico publicado en 2012

Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG.

artículo científico publicado en 2013

Inhibitors of Mutant Isocitrate Dehydrogenases 1 and 2 (mIDH1/2): An Update and Perspective

artículo científico publicado en 2018

Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein

artículo científico publicado en 2013

Mutant IDH Sensitizes Gliomas to Endoplasmic Reticulum Stress and Triggers Apoptosis via miR-183-Mediated Inhibition of Semaphorin 3E

artículo científico publicado en 2019

Mutant IDH1 inhibits PI3K/Akt signaling in human glioma.

artículo científico publicado en 2014

Mutational analysis of D2HGDH and L2HGDH in brain tumours without IDH1 or IDH2 mutations.

artículo científico publicado en 2011

NDRG1 prognosticates the natural course of disease in WHO grade II glioma

artículo científico publicado en 2014

OS10.2 R-2-Hydroxyglutarate shapes the immune microenvironment in IDH1-mutant gliomas.

artículo científico publicado en 2017

OS2.2 Paracrine impairment of antitumor T cell immunity by IDH1-mutant gliomas.

artículo científico publicado en 2016

Pan-mutant-IDH1 inhibitor BAY1436032 is highly effective against human IDH1 mutant acute myeloid leukemia in vivo.

artículo científico publicado en 2017

Pretreatment d-2-hydroxyglutarate serum levels negatively impact on outcome in IDH1-mutated acute myeloid leukemia.

artículo científico publicado en 2015

Profiling of gallbladder carcinoma reveals distinct miRNA profiles and activation of STAT1 by the tumor suppressive miRNA-145-5p

artículo científico publicado en 2019

Proximity ligation assay evaluates IDH1R132H presentation in gliomas

artículo científico publicado en 2015

Rapid detection of 2-hydroxyglutarate in frozen sections of IDH mutant tumors by MALDI-TOF mass spectrometry.

artículo científico publicado en 2018

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations

artículo científico publicado en 2013

Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway

artículo científico publicado en 2014

Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate

scientific article published on 09 July 2018

T-loop phosphorylation of Arabidopsis CDKA;1 is required for its function and can be partially substituted by an aspartate residue

artículo científico publicado en 2007

The Arabidopsis thaliana F-box protein FBL17 is essential for progression through the second mitosis during pollen development

artículo científico publicado en 2009

mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy

artículo científico publicado en 2013

Lista de obras de Stefan Pusch

A cell-based MAPK reporter assay reveals synergistic MAPK pathway activity suppression by MAPK inhibitor combination in BRAF-driven pediatric low-grade glioma cells

A general G1/S-phase cell-cycle control module in the flowering plant Arabidopsis thaliana

A vaccine targeting mutant IDH1 induces antitumour immunity

Analysis of the subcellular localization, function, and proteolytic control of the Arabidopsis cyclin-dependent kinase inhibitor ICK1/KRP1.

Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody

Bimolecular-Fluorescence Complementation Assay to Monitor Kinase–Substrate Interactions In Vivo ⬇️

Brain tumour cells interconnect to a functional and resistant network

CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas

CIC protein instability contributes to tumorigenesis in glioblastoma

Characterization of the epithelial membrane protein 3 interaction network reveals a potential functional link to mitogenic signal transduction regulation

Chromosome 8p tumor suppressor genes SH2D4A and SORBS3 cooperate to inhibit interleukin-6 signaling in hepatocellular carcinoma

Control of cell proliferation, organ growth, and DNA damage response operate independently of dephosphorylation of the Arabidopsis Cdk1 homolog CDKA;1.

D-2-Hydroxyglutarate producing neo-enzymatic activity inversely correlates with frequency of the type of isocitrate dehydrogenase 1 mutations found in glioma

Design, synthesis and biological activity of 3-pyrazine-2-yl-oxazolidin-2-ones as novel, potent and selective inhibitors of mutant isocitrate dehydrogenase 1.

Detection of 2-hydroxyglutarate in formalin-fixed paraffin-embedded glioma specimens by gas chromatography/mass spectrometry

Glioma IDH1 mutation patterns off the beaten track.

IDH2 Mutations Define a Unique Subtype of Breast Cancer with Altered Nuclear Polarity

Identification of a Prognostic Hypoxia-Associated Gene Set in IDH-Mutant Glioma

Identification of a novel inactivating mutation in Isocitrate Dehydrogenase 1 (IDH1-R314C) in a high grade astrocytoma.

Identification of kinase substrates by bimolecular complementation assays ⬇️

Identification of novel allosteric inhibitors of mutant isocitrate dehydrogenase 1 by cross docking-based virtual screening.

Immunohistochemical testing of BRAF V600E status in 1,120 tumor tissue samples of patients with brain metastases

Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG.

Inhibitors of Mutant Isocitrate Dehydrogenases 1 and 2 (mIDH1/2): An Update and Perspective

Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein

Mutant IDH Sensitizes Gliomas to Endoplasmic Reticulum Stress and Triggers Apoptosis via miR-183-Mediated Inhibition of Semaphorin 3E

Mutant IDH1 inhibits PI3K/Akt signaling in human glioma.

Mutational analysis of D2HGDH and L2HGDH in brain tumours without IDH1 or IDH2 mutations.

NDRG1 prognosticates the natural course of disease in WHO grade II glioma

OS10.2 R-2-Hydroxyglutarate shapes the immune microenvironment in IDH1-mutant gliomas.

OS2.2 Paracrine impairment of antitumor T cell immunity by IDH1-mutant gliomas.

Pan-mutant-IDH1 inhibitor BAY1436032 is highly effective against human IDH1 mutant acute myeloid leukemia in vivo.

Pretreatment d-2-hydroxyglutarate serum levels negatively impact on outcome in IDH1-mutated acute myeloid leukemia.

Profiling of gallbladder carcinoma reveals distinct miRNA profiles and activation of STAT1 by the tumor suppressive miRNA-145-5p

Proximity ligation assay evaluates IDH1R132H presentation in gliomas

Rapid detection of 2-hydroxyglutarate in frozen sections of IDH mutant tumors by MALDI-TOF mass spectrometry.

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations

Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway

Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate

T-loop phosphorylation of Arabidopsis CDKA;1 is required for its function and can be partially substituted by an aspartate residue

The Arabidopsis thaliana F-box protein FBL17 is essential for progression through the second mitosis during pollen development

mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy