Lista de obras - Erik Sjögren - Dominio Público Uruguay

A Model-Based Approach To Assessing the Importance of Intracellular Binding Sites in Doxorubicin Disposition

artículo científico publicado en 2017

A miniaturized in vitro release method for investigating drug-release mechanisms.

artículo científico publicado en 2015

Assessment of Free Drug Concentration in Cyclodextrin Formulations Is Essential to Determine Drug Potency in Functional In Vitro Assays.

artículo científico publicado en 2016

Clinical testing of three novel transient receptor potential cation channel subfamily V member 1 antagonists in a pharmacodynamic intradermal capsaicin model.

artículo científico publicado en 2018

Combining in vitro and in silico methods for better prediction of surfactant effects on the absorption of poorly water soluble drugs-a fenofibrate case example

artículo científico publicado en 2014

Computational fluid dynamics (CFD) studies of a miniaturized dissolution system.

artículo científico publicado en 2017

Concomitant intake of alcohol may increase the absorption of poorly soluble drugs.

artículo científico publicado en 2014

Direct In Vivo Human Intestinal Permeability (Peff ) Determined with Different Clinical Perfusion and Intubation Methods

artículo científico publicado en 2014

Effects of verapamil on the pharmacokinetics and hepatobiliary disposition of fexofenadine in pigs

artículo científico publicado en 2013

Excised segments of rat small intestine in Ussing chamber studies: A comparison of native and stripped tissue viability and permeability to drugs.

artículo científico publicado en 2016

Hepatic disposition of ximelagatran and its metabolites in pig; prediction of the impact of membrane transporters through a simple disposition model.

artículo científico publicado en 2010

Human in vivo regional intestinal permeability: quantitation using site-specific drug absorption data

artículo científico publicado en 2015

In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically Based Absorption Models.

artículo científico publicado en 2016

In Vivo Drug Delivery Performance of Lipiodol-Based Emulsion or Drug-Eluting Beads in Patients with Hepatocellular Carcinoma.

artículo científico publicado en 2016

In Vivo Mechanisms of Intestinal Drug Absorption from Aprepitant Nanoformulations

artículo científico publicado en 2017

In Vivo Predictive Dissolution (IPD) and Biopharmaceutical Modeling and Simulation: Future Use of Modern Approaches and Methodologies in a Regulatory Context.

artículo científico publicado en 2017

In vivo methods for drug absorption - comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient characterization including food effects.

artículo científico

Lipiodol does not affect the tissue distribution of intravenous doxorubicin infusion in pigs

artículo científico publicado en 2016

Online capillary solid phase extraction and liquid chromatographic separation with quantitative tandem mass spectrometric detection (SPE-LC-MS/MS) of ximelagatran and its metabolites in a complex matrix.

artículo científico publicado en 2008

Optimal experimental design for assessment of enzyme kinetics in a drug discovery screening environment.

artículo científico publicado en 2011

PBPK models for the prediction of in vivo performance of oral dosage forms

artículo científico publicado en 2013

Pharmacokinetics of an injectable modified-release 2-hydroxyflutamide formulation in the human prostate gland using a semiphysiologically based biopharmaceutical model

artículo científico publicado en 2014

Preclinical Effect of Absorption Modifying Excipients on Rat Intestinal Transport of Model Compounds and the Mucosal Barrier Marker 51Cr-EDTA.

artículo científico publicado en 2017

Preclinical characterization of three transient receptor potential vanilloid receptor 1 antagonists for early use in human intradermal microdose analgesic studies.

artículo científico publicado en 2018

Pulmonary Dissolution of Poorly Soluble Compounds Studied in an ex Vivo Rat Lung Model

scientific article published on 11 June 2019

Pulmonary absorption - estimation of effective pulmonary permeability and tissue retention of ten drugs using an ex-vivo rat model and computational analysis

artículo científico publicado en 2017

Regional Intestinal Permeability in Dogs: Biopharmaceutical Aspects for Development of Oral Modified-Release Dosage Forms

artículo científico publicado en 2016

Regional Intestinal Permeability in Rats: A Comparison of Methods.

artículo científico publicado en 2017

Regional Intestinal Permeability of Three Model Drugs in Human

article

Reply to "Comment on 'In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically Based Absorption Models'".

artículo científico publicado en 2016

Reply to "Comment on 'In Vivo Drug Delivery Performance of Lipiodol-Based Emulsion or Drug-Eluting Beads in Patients with Hepatocellular Carcinoma'".

artículo científico publicado en 2017

The effects of lipiodol and cyclosporin A on the hepatobiliary disposition of doxorubicin in pigs

artículo científico publicado en 2014

The multiple depletion curves method provides accurate estimates of intrinsic clearance (CLint), maximum velocity of the metabolic reaction (Vmax), and Michaelis constant (Km): accuracy and robustness evaluated through experimental data and Monte Ca

artículo científico publicado en 2008

The pharmacokinetics and hepatic disposition of repaglinide in pigs: mechanistic modeling of metabolism and transport.

artículo científico publicado en 2012

Treatment of intermediate stage hepatocellular carcinoma: a review of intrahepatic doxorubicin drug-delivery systems

artículo científico publicado en 2014

Lista de obras de Erik Sjögren

A Model-Based Approach To Assessing the Importance of Intracellular Binding Sites in Doxorubicin Disposition

A miniaturized in vitro release method for investigating drug-release mechanisms.

Assessment of Free Drug Concentration in Cyclodextrin Formulations Is Essential to Determine Drug Potency in Functional In Vitro Assays.

Clinical testing of three novel transient receptor potential cation channel subfamily V member 1 antagonists in a pharmacodynamic intradermal capsaicin model.

Combining in vitro and in silico methods for better prediction of surfactant effects on the absorption of poorly water soluble drugs-a fenofibrate case example

Computational fluid dynamics (CFD) studies of a miniaturized dissolution system.

Concomitant intake of alcohol may increase the absorption of poorly soluble drugs.

Direct In Vivo Human Intestinal Permeability (Peff ) Determined with Different Clinical Perfusion and Intubation Methods

Effects of verapamil on the pharmacokinetics and hepatobiliary disposition of fexofenadine in pigs

Excised segments of rat small intestine in Ussing chamber studies: A comparison of native and stripped tissue viability and permeability to drugs.

Hepatic disposition of ximelagatran and its metabolites in pig; prediction of the impact of membrane transporters through a simple disposition model.

Human in vivo regional intestinal permeability: quantitation using site-specific drug absorption data

In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically Based Absorption Models.

In Vivo Drug Delivery Performance of Lipiodol-Based Emulsion or Drug-Eluting Beads in Patients with Hepatocellular Carcinoma.

In Vivo Mechanisms of Intestinal Drug Absorption from Aprepitant Nanoformulations

In Vivo Predictive Dissolution (IPD) and Biopharmaceutical Modeling and Simulation: Future Use of Modern Approaches and Methodologies in a Regulatory Context.

In vivo methods for drug absorption - comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient characterization including food effects.

Lipiodol does not affect the tissue distribution of intravenous doxorubicin infusion in pigs

Online capillary solid phase extraction and liquid chromatographic separation with quantitative tandem mass spectrometric detection (SPE-LC-MS/MS) of ximelagatran and its metabolites in a complex matrix.

Optimal experimental design for assessment of enzyme kinetics in a drug discovery screening environment.

PBPK models for the prediction of in vivo performance of oral dosage forms

Pharmacokinetics of an injectable modified-release 2-hydroxyflutamide formulation in the human prostate gland using a semiphysiologically based biopharmaceutical model

Preclinical Effect of Absorption Modifying Excipients on Rat Intestinal Transport of Model Compounds and the Mucosal Barrier Marker 51Cr-EDTA.

Preclinical characterization of three transient receptor potential vanilloid receptor 1 antagonists for early use in human intradermal microdose analgesic studies.

Pulmonary Dissolution of Poorly Soluble Compounds Studied in an ex Vivo Rat Lung Model

Pulmonary absorption - estimation of effective pulmonary permeability and tissue retention of ten drugs using an ex-vivo rat model and computational analysis

Regional Intestinal Permeability in Dogs: Biopharmaceutical Aspects for Development of Oral Modified-Release Dosage Forms

Regional Intestinal Permeability in Rats: A Comparison of Methods.

Regional Intestinal Permeability of Three Model Drugs in Human

Reply to "Comment on 'In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically Based Absorption Models'".

Reply to "Comment on 'In Vivo Drug Delivery Performance of Lipiodol-Based Emulsion or Drug-Eluting Beads in Patients with Hepatocellular Carcinoma'".

The effects of lipiodol and cyclosporin A on the hepatobiliary disposition of doxorubicin in pigs

The multiple depletion curves method provides accurate estimates of intrinsic clearance (CLint), maximum velocity of the metabolic reaction (Vmax), and Michaelis constant (Km): accuracy and robustness evaluated through experimental data and Monte Ca

The pharmacokinetics and hepatic disposition of repaglinide in pigs: mechanistic modeling of metabolism and transport.

Treatment of intermediate stage hepatocellular carcinoma: a review of intrahepatic doxorubicin drug-delivery systems