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Lista de obras de Zhiqing Liu

Antimicrobial and Antioxidant Polyketides from a Deep-Sea-Derived Fungus <i>Aspergillus versicolor</i> SH0105

artículo científico publicado en 2020

BH4 domain of Bcl-2 as a novel target for cancer therapy

artículo científico publicado en 2015

Design, Synthesis, and Pharmacological Evaluation of Analogues Derived from the PLEV Tetrapeptide as Protein-Protein Interaction Modulators of Voltage-Gated Sodium Channel 1.6.

scientific article published on 15 October 2020

Design, synthesis and pharmacological evaluation of 2-(thiazol-2-amino)-4-arylaminopyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors.

artículo científico publicado en 2014

Design, synthesis, and pharmacological evaluation of benzamide derivatives as glucokinase activators.

artículo científico publicado en 2012

Direct Activation of Bax Protein for Cancer Therapy

artículo científico publicado en 2015

Discovery of novel 2,4-diarylaminopyrimidine analogues (DAAPalogues) showing potent inhibitory activities against both wild-type and mutant ALK kinases.

artículo científico publicado en 2014

Discovery of phenanthridine analogues as novel chemical probes disrupting the binding of DNA to ΔFosB homodimers and ΔFosB/JunD heterodimers

artículo científico publicado en 2020

Discovery of potent and selective BRD4 inhibitors capable of blocking TLR3-induced acute airway inflammation

scientific article published on 03 April 2018

Efficacy of Novel Highly Specific Bromodomain-Containing Protein 4 Inhibitors in Innate Inflammation-Driven Airway Remodeling

scientific article published on 01 January 2019

Exchange proteins directly activated by cAMP (EPACs): Emerging therapeutic targets

artículo científico publicado en 2017

Functional Modulation of Voltage-Gated Sodium Channels by a FGF14-Based Peptidomimetic.

artículo científico publicado en 2018

Identification of novel 2-(benzo[d]isoxazol-3-yl)-2-oxo-N-phenylacetohydrazonoyl cyanide analoguesas potent EPAC antagonists

artículo científico publicado en 2017

Identification of peptidomimetics as novel chemical probes modulating fibroblast growth factor 14 (FGF14) and voltage-gated sodium channel 1.6 (Nav1.6) protein-protein interactions

scientific article published on 15 December 2018

Mucosal Bromodomain-Containing Protein 4 (BRD4) Mediates Aeroallergen-induced Inflammation and Remodeling

artículo científico publicado en 2018

Novel 2,4-Diarylaminopyrimidine Analogues (DAAPalogues) Showing Potent c-Met/ALK Multikinase Inhibitory Activities

artículo científico publicado en 2014

Pharmacoproteomics reveal novel protective activity of bromodomain containing 4 inhibitors on vascular homeostasis in TLR3-mediated airway remodeling

scientific article published on 10 June 2019

Selective Antagonists of the Bronchiolar Epithelial NF-κB-Bromodomain-Containing Protein 4 Pathway in Viral-Induced Airway Inflammation

artículo científico publicado en 2018

Structure-Activity Relationship Studies of Substituted 2-(Isoxazol-3-yl)-2-oxo-N'-phenyl-acetohydrazonoyl Cyanide Analogues: Identification of Potent Exchange Proteins Directly Activated by cAMP (EPAC) Antagonists

artículo científico publicado en 2015

Structure-activity relationships of 2-substituted phenyl-N-phenyl-2-oxoacetohydrazonoyl cyanides as novel antagonists of exchange proteins directly activated by cAMP (EPACs).

artículo científico publicado en 2017

Structure-guided drug design identifies a BRD4-selective small molecule that suppresses HIV

artículo científico publicado en 2019

Synthesis and Biochemical Evaluation of Non-Cyclic Nucleotide Exchange Protein Directly Activated by cAMP 1 (EPAC1) Regulators

scientific article published on 28 April 2020