Lista de obras - Stephen D. Weeks - Dominio Público Uruguay

A Carrier Protein Strategy Yields the Structure of Dalbavancin

artículo científico publicado en 2012

Acylated sulfonamide adenosines as potent inhibitors of the adenylate-forming enzyme superfamily

artículo científico publicado en 2019

Characterization of Mutants of Human Small Heat Shock Protein HspB1 Carrying Replacements in the N-Terminal Domain and Associated with Hereditary Motor Neuron Diseases

artículo científico publicado en 2015

Characterization of human small heat shock protein HSPB1 α-crystallin domain localized mutants associated with hereditary motor neuron diseases.

artículo científico publicado en 2018

Characterization of oligosaccharides from the chondroitin sulfates. (1)H-NMR and (13)C-NMR studies of reduced disaccharides and tetrasaccharides.

artículo científico publicado en 2001

Comparative analysis of pyrimidine substituted aminoacyl-sulfamoyl nucleosides as potential inhibitors targeting class I aminoacyl-tRNA synthetases

scientific article published on 05 April 2019

Crystal structures of Lys-63-linked tri- and di-ubiquitin reveal a highly extended chain architecture

artículo científico publicado en 2009

Crystal structures of the Pyrococcus abyssi Sm core and its complex with RNA. Common features of RNA binding in archaea and eukarya

artículo científico publicado en 2003

Discovery of a new Pro-Pro endopeptidase, PPEP-2, provides mechanistic insights into the differences in substrate specificity within the PPEP family

artículo científico publicado en 2018

Dissecting the functional role of the N-terminal domain of the human small heat shock protein HSPB6.

artículo científico publicado en 2014

Elucidation of the molecular mechanisms of two nanobodies that inhibit thrombin-activatable fibrinolysis inhibitor activation and activated thrombin-activatable fibrinolysis inhibitor activity

artículo científico publicado en 2016

Expression, purification and preliminary biochemical and structural characterization of the leucine rich repeat namesake domain of leucine rich repeat kinase 2.

artículo científico publicado en 2012

Family-wide analysis of aminoacyl-sulfamoyl-3-deazaadenosine analogues as inhibitors of aminoacyl-tRNA synthetases

artículo científico publicado en 2018

Heptyl α-D-mannosides grafted on a β-cyclodextrin core to interfere with Escherichia coli adhesion: an in vivo multivalent effect

artículo científico publicado en 2013

Interaction of transportin-SR2 with Ras-related nuclear protein (Ran) GTPase

artículo científico publicado en 2013

MALT1 auto-proteolysis is essential for NF-κB-dependent gene transcription in activated lymphocytes

artículo científico publicado en 2014

Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction

scientific article published on 20 February 2020

Molecular structure and dynamics of the dimeric human small heat shock protein HSPB6

artículo científico publicado en 2014

Rational design of an XNA ligase through docking of unbound nucleic acids to toroidal proteins

scientific article published on 01 July 2019

Real-time monitoring of the membrane-binding and insertion properties of the cholesterol-dependent cytolysin anthrolysin O from Bacillus anthracis.

artículo científico publicado en 2006

SUMO fusions and SUMO-specific protease for efficient expression and purification of proteins.

artículo científico publicado en 2004

Small-angle X-ray scattering to obtain models of multivalent lectin-glycan complexes.

artículo científico publicado en 2014

Specific sequences in the N-terminal domain of human small heat-shock protein HSPB6 dictate preferential hetero-oligomerization with the orthologue HSPB1. ⬇️

artículo científico publicado en 2017

Structural Basis for the Interaction of a Human Small Heat Shock Protein with the 14-3-3 Universal Signaling Regulator

artículo científico publicado en 2016

Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases

artículo científico publicado en 2020

Structural Insights into the Mechanism of a Nanobody That Stabilizes PAI-1 and Modulates Its Activity

scientific article published on 15 August 2020

Structural basis of bacterial defense against g-type lysozyme-based innate immunity

artículo científico publicado en 2013

Structural insights into the activity and regulation of human Josephin-2

artículo científico publicado en 2019

Structure of Ostertagia ostertagi ASP-1: insights into disulfide-mediated cyclization and dimerization

artículo científico publicado en 2013

Structure of the complex between teicoplanin and a bacterial cell-wall peptide: use of a carrier-protein approach ⬇️

artículo científico publicado el 14 de marzo de 2013

Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors

artículo científico publicado en 2020

The Role of the Arginine in the Conserved N-Terminal Domain RLFDQxFG Motif of Human Small Heat Shock Proteins HspB1, HspB4, HspB5, HspB6, and HspB8

artículo científico publicado en 2018

The preferential heterodimerization of human small heat shock proteins HSPB1 and HSPB6 is dictated by the N-terminal domain ⬇️

artículo científico publicado en 2016

Three-Dimensional Structure of α-Crystallin Domain Dimers of Human Small Heat Shock Proteins HSPB1 and HSPB6 ⬇️

artículo científico publicado el 30 de mayo de 2011

Lista de obras de Stephen D. Weeks

A Carrier Protein Strategy Yields the Structure of Dalbavancin

Acylated sulfonamide adenosines as potent inhibitors of the adenylate-forming enzyme superfamily

Characterization of Mutants of Human Small Heat Shock Protein HspB1 Carrying Replacements in the N-Terminal Domain and Associated with Hereditary Motor Neuron Diseases

Characterization of human small heat shock protein HSPB1 α-crystallin domain localized mutants associated with hereditary motor neuron diseases.

Characterization of oligosaccharides from the chondroitin sulfates. (1)H-NMR and (13)C-NMR studies of reduced disaccharides and tetrasaccharides.

Comparative analysis of pyrimidine substituted aminoacyl-sulfamoyl nucleosides as potential inhibitors targeting class I aminoacyl-tRNA synthetases

Crystal structures of Lys-63-linked tri- and di-ubiquitin reveal a highly extended chain architecture

Crystal structures of the Pyrococcus abyssi Sm core and its complex with RNA. Common features of RNA binding in archaea and eukarya

Discovery of a new Pro-Pro endopeptidase, PPEP-2, provides mechanistic insights into the differences in substrate specificity within the PPEP family

Dissecting the functional role of the N-terminal domain of the human small heat shock protein HSPB6.

Elucidation of the molecular mechanisms of two nanobodies that inhibit thrombin-activatable fibrinolysis inhibitor activation and activated thrombin-activatable fibrinolysis inhibitor activity

Expression, purification and preliminary biochemical and structural characterization of the leucine rich repeat namesake domain of leucine rich repeat kinase 2.

Family-wide analysis of aminoacyl-sulfamoyl-3-deazaadenosine analogues as inhibitors of aminoacyl-tRNA synthetases

Heptyl α-D-mannosides grafted on a β-cyclodextrin core to interfere with Escherichia coli adhesion: an in vivo multivalent effect

Interaction of transportin-SR2 with Ras-related nuclear protein (Ran) GTPase

MALT1 auto-proteolysis is essential for NF-κB-dependent gene transcription in activated lymphocytes

Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction

Molecular structure and dynamics of the dimeric human small heat shock protein HSPB6

Rational design of an XNA ligase through docking of unbound nucleic acids to toroidal proteins

Real-time monitoring of the membrane-binding and insertion properties of the cholesterol-dependent cytolysin anthrolysin O from Bacillus anthracis.

SUMO fusions and SUMO-specific protease for efficient expression and purification of proteins.

Small-angle X-ray scattering to obtain models of multivalent lectin-glycan complexes.

Specific sequences in the N-terminal domain of human small heat-shock protein HSPB6 dictate preferential hetero-oligomerization with the orthologue HSPB1. ⬇️

Structural Basis for the Interaction of a Human Small Heat Shock Protein with the 14-3-3 Universal Signaling Regulator

Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases

Structural Insights into the Mechanism of a Nanobody That Stabilizes PAI-1 and Modulates Its Activity

Structural basis of bacterial defense against g-type lysozyme-based innate immunity

Structural insights into the activity and regulation of human Josephin-2

Structure of Ostertagia ostertagi ASP-1: insights into disulfide-mediated cyclization and dimerization

Structure of the complex between teicoplanin and a bacterial cell-wall peptide: use of a carrier-protein approach ⬇️

Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors

The Role of the Arginine in the Conserved N-Terminal Domain RLFDQxFG Motif of Human Small Heat Shock Proteins HspB1, HspB4, HspB5, HspB6, and HspB8

The preferential heterodimerization of human small heat shock proteins HSPB1 and HSPB6 is dictated by the N-terminal domain ⬇️

Three-Dimensional Structure of α-Crystallin Domain Dimers of Human Small Heat Shock Proteins HSPB1 and HSPB6 ⬇️