Lista de obras - Mario Santinami - Dominio Público Uruguay

A phase II trial of vaccination with autologous, tumor-derived heat-shock protein peptide complexes Gp96, in combination with GM-CSF and interferon-α in metastatic melanoma patients

article by Lorenzo Pilla et al published 8 October 2005 in Cancer Immunology, Immunotherapy

A variant in FTO shows association with melanoma risk not due to BMI

artículo científico publicado en 2013

Accuracy and prognostic value of sentinel lymph node biopsy in head and neck melanomas.

artículo científico

Adjuvant Dabrafenib plus Trametinib in Stage III BRAF-Mutated Melanoma.

artículo científico publicado en 2017

Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial

artículo científico publicado en 2008

Adjuvant therapy with pegylated interferon alfa-2b versus observation in resected stage III melanoma: a phase III randomized controlled trial of health-related quality of life and symptoms by the European Organisation for Research and Treatment of C

artículo científico publicado en 2009

Advanced Extremity Soft Tissue Sarcoma: Prognostic Effect of Isolated Limb Perfusion in a Series of 88 Patients Treated at a Single Institution

artículo científico publicado en 2006

Alternative activation of human plasmacytoid DCs in vitro and in melanoma lesions: involvement of LAG-3.

artículo científico publicado en 2014

Analysis of surrogate gene expression markers in peripheral blood of melanoma patients to predict treatment outcome of adjuvant pegylated interferon alpha 2b (EORTC 18991 side study).

artículo científico publicado en 2013

Antitumor activity of hyperthermia alone or in combination with cisplatin and melphalan in primary cultures of human malignant melanoma

article

Armed antibodies for cancer treatment: a promising tool in a changing era.

artículo científico publicado en 2014

Association of promoter polymorphism -765G>C in the PTGS2 gene with malignant melanoma in Italian patients and its correlation to gene expression in dermal fibroblasts.

artículo científico publicado en 2014

Atypical pleomorphic epithelioid angiomyolipoma localized to the pelvis: a case report and review of the literature.

artículo científico publicado en 2004

Automated segmentation of pigmented skin lesions in multispectral imaging.

artículo científico publicado en 2005

Banked venous homograft replacement of the inferior vena cava for primary leiomyosarcoma

artículo científico publicado en 2006

Biological insights into BRAF(V600) mutations in melanoma patient: Not mere therapeutic targets

artículo científico publicado en 2013

CDKN2A and MC1R variants influence dermoscopic and confocal features of benign melanocytic lesions in multiple melanoma patients.

artículo científico publicado en 2013

Chordoma: natural history and results in 28 patients treated at a single institution.

artículo científico publicado en 2003

Circulating melanoma cells and distant metastasis-free survival in stage III melanoma patients with or without adjuvant interferon treatment (EORTC 18991 side study).

artículo científico publicado en 2009

Clinical and immunologic responses in melanoma patients vaccinated with MAGE-A3-genetically modified lymphocytes

artículo científico publicado en 2012

Constitutive expression and costimulatory function of LIGHT/TNFSF14 on human melanoma cells and melanoma-derived microvesicles.

artículo científico publicado en 2005

Cutaneous Melanoma in Childhood and Adolescence Shows Frequent Loss of INK4A and Gain of KIT

article

Cutaneous melanoma in children and adolescents: the Italian rare tumors in pediatric age project experience.

artículo científico publicado en 2013

DNA fragmentation and cell proliferation correlated with tumor grade in patients with hepatocellular carcinoma

scientific article published on 01 October 2002

Deliberate hypoxic pelvic and limb chemoperfusion in the treatment of recurrent melanoma.

artículo científico publicado en 2002

Detection of mutated BRAFV600E variant in circulating DNA of stage III–IV melanoma patients

artículo científico publicado en 2007

Differences in Clinicopathological Features and Distribution of Risk Factors in Italian Melanoma Patients

article

Does Melanoma Behave Differently in Younger Children Than in Adults? A Retrospective Study of 33 Cases of Childhood Melanoma From a Single Institution

artículo científico publicado en 2005

Effect of long-term adjuvant therapy with interferon alpha-2a in patients with regional node metastases from cutaneous melanoma: a randomised trial.

artículo científico publicado en 2001

Effects of cyclophosphamide and IL-2 on regulatory CD4+ T cell frequency and function in melanoma patients vaccinated with HLA-class I peptides: impact on the antigen-specific T cell response

artículo científico publicado en 2013

Elective lymph node dissection for melanoma: two perspectives

artículo científico publicado el 1 de marzo de 1992

Electrochemotherapy: a good idea in recurrent basal cell carcinoma treatment

scientific article published on 25 February 2015

Enrichment of CD56(dim)KIR + CD57 + highly cytotoxic NK cells in tumour-infiltrated lymph nodes of melanoma patients

artículo científico publicado en 2014

Enrichment of KIR+CD57+ highly cytotoxic NK cells in sentinel lymph nodes of melanoma patients.

artículo científico publicado en 2014

Excision of Primary Melanoma Should Allow Primary Closure of the Wound ⬇️

artículo científico publicado el 1 de enero de 1995

Factors predictive of pelvic lymph node involvement and outcomes in melanoma patients with metastatic sentinel lymph node of the groin: A multicentre study

artículo científico publicado en 2015

HLA antigens in familial and sporadic cutaneous melanoma.

artículo científico publicado en 1988

Heat shock proteins and their use as anticancer vaccines.

artículo científico publicado en 2004

High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients

artículo científico publicado en 2009

Hypoxic pelvic and limb perfusion with melphalan and mitomycin C for recurrent limb melanoma

scientific article published on 01 February 2003

Immediate or delayed dissection of regional nodes in patients with melanoma of the trunk: a randomised trial. WHO Melanoma Programme.

artículo científico publicado en 1998

Immunization of stage IV melanoma patients with Melan-A/MART-1 and gp100 peptides plus IFN-alpha results in the activation of specific CD8(+) T cells and monocyte/dendritic cell precursors.

artículo científico publicado en 2006

Immunomodulatory Factors Control the Fate of Melanoma Tumor Initiating Cells.

artículo científico publicado en 2016

Immunotherapy of melanoma

artículo científico publicado en 2003

Impaired STAT phosphorylation in T cells from melanoma patients in response to IL-2: association with clinical stage

artículo científico publicado en 2009

Intralesional administration of L19-IL2/L19-TNF in stage III or stage IVM1a melanoma patients: results of a phase II study

artículo científico publicado en 2015

Ipilimumab and fotemustine in patients with advanced melanoma (NIBIT-M1): an open-label, single-arm phase 2 trial

artículo científico publicado en 2012

Isolated limb perfusion with the tumor-targeting human monoclonal antibody-cytokine fusion protein L19-TNF plus melphalan and mild hyperthermia in patients with locally advanced extremity melanoma

article published in 2012

Isolation perfusion in extracorporeal circulation with interleukin-2 and lymphokine-activated killer cells in the treatment of in-transit metastases from limb cutaneous melanoma

artículo científico publicado en 1995

Isolation perfusion of the lower limb with platinum

scientific article published on 01 June 1988

Lack of terminally differentiated tumor-specific CD8+ T cells at tumor site in spite of antitumor immunity to self-antigens in human metastatic melanoma ⬇️

artículo científico publicado el 15 de mayo de 2003

Limited induction of tumor cross-reactive T cells without a measurable clinical benefit in early melanoma patients vaccinated with human leukocyte antigen class I-modified peptides

artículo científico publicado en 2012

Long-term results of the randomized phase III trial EORTC 18991 of adjuvant therapy with pegylated interferon alfa-2b versus observation in resected stage III melanoma

artículo científico publicado en 2012

Longer Follow-Up Confirms Relapse-Free Survival Benefit With Adjuvant Dabrafenib Plus Trametinib in Patients With Resected BRAF V600-Mutant Stage III Melanoma

article

Management of nodal metastases from head and neck melanoma

artículo científico publicado en 1989

Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential.

artículo científico publicado en 2007

Melanoma immunology: past, present and future.

artículo científico publicado en 2007

Micro-melanoma detection: a clinical study on 206 consecutive cases of pigmented skin lesions with a diameter < or = 3 mm

scientific article published on 01 September 2006

Modified peptides in anti-cancer vaccines: are we eventually improving anti-tumour immunity?

scientific article published on 08 November 2008

Modulation of microenvironment acidity reverses anergy in human and murine tumor-infiltrating T lymphocytes.

artículo científico publicado en 2012

Multispectral imaging and artificial neural network: mimicking the management decision of the clinician facing pigmented skin lesions.

artículo científico publicado en 2007

NFATc2 is an intrinsic regulator of melanoma dedifferentiation

artículo científico publicado en 2015

New common variants affecting susceptibility to basal cell carcinoma

artículo científico publicado en 2009

Number of excised lymph nodes as a quality assurance measure for lymphadenectomy in melanoma

artículo científico publicado en 2014

Overcoming melanoma resistance to vemurafenib by targeting CCL2-induced miR-34a, miR-100 and miR-125b

artículo científico publicado en 2015

Patient-reported outcomes in patients with resected, high-risk melanoma with BRAFV600E or BRAFV600K mutations treated with adjuvant dabrafenib plus trametinib (COMBI-AD): a randomised, placebo-controlled, phase 3 trial

scientific article published on 27 March 2019

Phase III trial comparing adjuvant treatment with pegylated interferon Alfa-2b versus observation: prognostic significance of autoantibodies--EORTC 18991.

artículo científico publicado en 2010

Prediction of survival in patients with thin melanoma: results from a multi-institution study.

artículo científico publicado en 2014

Prognosis of skin melanoma with regional node metastases (stage II)

scientific article published on 01 April 1984

Prognostic factors in Merkel cell carcinoma patients undergoing sentinel node biopsy.

artículo científico publicado en 2017

Pure desmoplastic melanoma: a melanoma with distinctive clinical behavior.

artículo científico publicado en 2010

Quality of surgery and outcome in extra-abdominal aggressive fibromatosis: a series of patients surgically treated at a single institution.

artículo científico publicado en 2003

Radical dissection after positive groin sentinel biopsy in melanoma patients: rate of further positive nodes.

artículo científico publicado en 2009

Reply to E. Hindié and K.R. Hess

artículo científico publicado en 2019

Response to Griewank and Bastian

Retroperitoneal soft tissue sarcomas: patterns of recurrence in 167 patients treated at a single institution.

artículo científico publicado en 2004

Sentinel and nonsentinel node status in stage IB and II melanoma patients: two-step prognostic indicators of survival.

artículo científico publicado en 2006

Seven years experience with hyperthermic perfusions in extracorporeal circulation for melanoma of the extremities

artículo científico publicado en 1989

Sex-specific effect of RNASEL rs486907 and miR-146a rs2910164 polymorphisms' interaction as a susceptibility factor for melanoma skin cancer.

artículo científico publicado en 2017

Single-institution series of early-stage Merkel cell carcinoma: long-term outcomes in 95 patients managed with surgery alone

scientific article published on 16 July 2009

Small nodular melanoma: the beginning of a life-threatening lesion. A clinical study on 11 cases.

artículo científico publicado en 2011

The number of excised lymph nodes is associated with survival of melanoma patients with lymph node metastasis

artículo científico publicado en 2014

The use of polytetrafluoroethylene to facilitate the vascular access in recurrent melanoma to limbs.

artículo científico publicado en 2012

Three-year follow-up of advanced melanoma patients who received ipilimumab plus fotemustine in the Italian Network for Tumor Biotherapy (NIBIT)-M1 phase II study

artículo científico publicado en 2014

Transcriptional profiling of melanoma sentinel nodes identify patients with poor outcome and reveal an association of CD30(+) T lymphocytes with progression

artículo científico

Treatment of primary or relapsing limb cancer by isolation perfusion with high-dose alpha-tumor necrosis factor, gamma-interferon, and melphalan

artículo científico publicado en 1994

Tumor-reactive CD8+ early effector T cells identified at tumor site in primary and metastatic melanoma.

artículo científico publicado en 2010

Ulceration and stage are predictive of interferon efficacy in melanoma: results of the phase III adjuvant trials EORTC 18952 and EORTC 18991.

artículo científico publicado en 2011

Vaccination: role in metastatic melanoma.

artículo científico publicado en 2006

World Health Organization experience in the treatment of melanoma.

artículo científico publicado en 2003

microRNA Expression in Sentinel Nodes from Progressing Melanoma Patients Identifies Networks Associated with Dysfunctional Immune Response

artículo científico

pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity

artículo científico publicado en 2010

Lista de obras de Mario Santinami

A phase II trial of vaccination with autologous, tumor-derived heat-shock protein peptide complexes Gp96, in combination with GM-CSF and interferon-α in metastatic melanoma patients

A variant in FTO shows association with melanoma risk not due to BMI

Accuracy and prognostic value of sentinel lymph node biopsy in head and neck melanomas.

Adjuvant Dabrafenib plus Trametinib in Stage III BRAF-Mutated Melanoma.

Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial

Adjuvant therapy with pegylated interferon alfa-2b versus observation in resected stage III melanoma: a phase III randomized controlled trial of health-related quality of life and symptoms by the European Organisation for Research and Treatment of C

Advanced Extremity Soft Tissue Sarcoma: Prognostic Effect of Isolated Limb Perfusion in a Series of 88 Patients Treated at a Single Institution

Alternative activation of human plasmacytoid DCs in vitro and in melanoma lesions: involvement of LAG-3.

Analysis of surrogate gene expression markers in peripheral blood of melanoma patients to predict treatment outcome of adjuvant pegylated interferon alpha 2b (EORTC 18991 side study).

Antitumor activity of hyperthermia alone or in combination with cisplatin and melphalan in primary cultures of human malignant melanoma

Armed antibodies for cancer treatment: a promising tool in a changing era.

Association of promoter polymorphism -765G>C in the PTGS2 gene with malignant melanoma in Italian patients and its correlation to gene expression in dermal fibroblasts.

Atypical pleomorphic epithelioid angiomyolipoma localized to the pelvis: a case report and review of the literature.

Automated segmentation of pigmented skin lesions in multispectral imaging.

Banked venous homograft replacement of the inferior vena cava for primary leiomyosarcoma

Biological insights into BRAF(V600) mutations in melanoma patient: Not mere therapeutic targets

CDKN2A and MC1R variants influence dermoscopic and confocal features of benign melanocytic lesions in multiple melanoma patients.

Chordoma: natural history and results in 28 patients treated at a single institution.

Circulating melanoma cells and distant metastasis-free survival in stage III melanoma patients with or without adjuvant interferon treatment (EORTC 18991 side study).

Clinical and immunologic responses in melanoma patients vaccinated with MAGE-A3-genetically modified lymphocytes

Constitutive expression and costimulatory function of LIGHT/TNFSF14 on human melanoma cells and melanoma-derived microvesicles.

Cutaneous Melanoma in Childhood and Adolescence Shows Frequent Loss of INK4A and Gain of KIT

Cutaneous melanoma in children and adolescents: the Italian rare tumors in pediatric age project experience.

DNA fragmentation and cell proliferation correlated with tumor grade in patients with hepatocellular carcinoma

Deliberate hypoxic pelvic and limb chemoperfusion in the treatment of recurrent melanoma.

Detection of mutated BRAFV600E variant in circulating DNA of stage III–IV melanoma patients

Differences in Clinicopathological Features and Distribution of Risk Factors in Italian Melanoma Patients

Does Melanoma Behave Differently in Younger Children Than in Adults? A Retrospective Study of 33 Cases of Childhood Melanoma From a Single Institution

Effect of long-term adjuvant therapy with interferon alpha-2a in patients with regional node metastases from cutaneous melanoma: a randomised trial.

Effects of cyclophosphamide and IL-2 on regulatory CD4+ T cell frequency and function in melanoma patients vaccinated with HLA-class I peptides: impact on the antigen-specific T cell response

Elective lymph node dissection for melanoma: two perspectives

Electrochemotherapy: a good idea in recurrent basal cell carcinoma treatment

Enrichment of CD56(dim)KIR + CD57 + highly cytotoxic NK cells in tumour-infiltrated lymph nodes of melanoma patients

Enrichment of KIR+CD57+ highly cytotoxic NK cells in sentinel lymph nodes of melanoma patients.

Excision of Primary Melanoma Should Allow Primary Closure of the Wound ⬇️

Factors predictive of pelvic lymph node involvement and outcomes in melanoma patients with metastatic sentinel lymph node of the groin: A multicentre study

HLA antigens in familial and sporadic cutaneous melanoma.

Heat shock proteins and their use as anticancer vaccines.

High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients

Hypoxic pelvic and limb perfusion with melphalan and mitomycin C for recurrent limb melanoma

Immediate or delayed dissection of regional nodes in patients with melanoma of the trunk: a randomised trial. WHO Melanoma Programme.

Immunization of stage IV melanoma patients with Melan-A/MART-1 and gp100 peptides plus IFN-alpha results in the activation of specific CD8(+) T cells and monocyte/dendritic cell precursors.

Immunomodulatory Factors Control the Fate of Melanoma Tumor Initiating Cells.

Immunotherapy of melanoma

Impaired STAT phosphorylation in T cells from melanoma patients in response to IL-2: association with clinical stage

Intralesional administration of L19-IL2/L19-TNF in stage III or stage IVM1a melanoma patients: results of a phase II study

Ipilimumab and fotemustine in patients with advanced melanoma (NIBIT-M1): an open-label, single-arm phase 2 trial

Isolated limb perfusion with the tumor-targeting human monoclonal antibody-cytokine fusion protein L19-TNF plus melphalan and mild hyperthermia in patients with locally advanced extremity melanoma

Isolation perfusion in extracorporeal circulation with interleukin-2 and lymphokine-activated killer cells in the treatment of in-transit metastases from limb cutaneous melanoma

Isolation perfusion of the lower limb with platinum

Lack of terminally differentiated tumor-specific CD8+ T cells at tumor site in spite of antitumor immunity to self-antigens in human metastatic melanoma ⬇️

Limited induction of tumor cross-reactive T cells without a measurable clinical benefit in early melanoma patients vaccinated with human leukocyte antigen class I-modified peptides

Long-term results of the randomized phase III trial EORTC 18991 of adjuvant therapy with pegylated interferon alfa-2b versus observation in resected stage III melanoma

Longer Follow-Up Confirms Relapse-Free Survival Benefit With Adjuvant Dabrafenib Plus Trametinib in Patients With Resected BRAF V600-Mutant Stage III Melanoma

Management of nodal metastases from head and neck melanoma

Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential.

Melanoma immunology: past, present and future.

Micro-melanoma detection: a clinical study on 206 consecutive cases of pigmented skin lesions with a diameter < or = 3 mm

Modified peptides in anti-cancer vaccines: are we eventually improving anti-tumour immunity?

Modulation of microenvironment acidity reverses anergy in human and murine tumor-infiltrating T lymphocytes.

Multispectral imaging and artificial neural network: mimicking the management decision of the clinician facing pigmented skin lesions.

NFATc2 is an intrinsic regulator of melanoma dedifferentiation

New common variants affecting susceptibility to basal cell carcinoma

Number of excised lymph nodes as a quality assurance measure for lymphadenectomy in melanoma

Overcoming melanoma resistance to vemurafenib by targeting CCL2-induced miR-34a, miR-100 and miR-125b

Patient-reported outcomes in patients with resected, high-risk melanoma with BRAFV600E or BRAFV600K mutations treated with adjuvant dabrafenib plus trametinib (COMBI-AD): a randomised, placebo-controlled, phase 3 trial

Phase III trial comparing adjuvant treatment with pegylated interferon Alfa-2b versus observation: prognostic significance of autoantibodies--EORTC 18991.

Prediction of survival in patients with thin melanoma: results from a multi-institution study.

Prognosis of skin melanoma with regional node metastases (stage II)

Prognostic factors in Merkel cell carcinoma patients undergoing sentinel node biopsy.

Pure desmoplastic melanoma: a melanoma with distinctive clinical behavior.

Quality of surgery and outcome in extra-abdominal aggressive fibromatosis: a series of patients surgically treated at a single institution.

Radical dissection after positive groin sentinel biopsy in melanoma patients: rate of further positive nodes.

Reply to E. Hindié and K.R. Hess

Response to Griewank and Bastian

Retroperitoneal soft tissue sarcomas: patterns of recurrence in 167 patients treated at a single institution.

Sentinel and nonsentinel node status in stage IB and II melanoma patients: two-step prognostic indicators of survival.

Seven years experience with hyperthermic perfusions in extracorporeal circulation for melanoma of the extremities

Sex-specific effect of RNASEL rs486907 and miR-146a rs2910164 polymorphisms' interaction as a susceptibility factor for melanoma skin cancer.