Lista de obras - Andrew J Deans - Dominio Público Uruguay

A defined role for multiple Fanconi anemia gene products in DNA-damage-associated ubiquitination.

artículo científico publicado en 2017

ALT control, delete: FANCM as an anti-cancer target in Alternative Lengthening of Telomeres

scientific article published on 01 December 2019

ASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress.

artículo científico publicado en 2017

ATP-dependent helicase activity is dispensable for the physiological functions of Recql4

scientific article published on 05 July 2019

Architecture and DNA Recognition Elements of the Fanconi Anemia FANCM-FAAP24 Complex

artículo científico publicado en 2013

Author Correction: The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)

scientific article published on 20 November 2019

BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage

artículo científico publicado en 2004

Brca1 inactivation induces p27(Kip1)-dependent cell cycle arrest and delayed development in the mouse mammary gland.

artículo científico publicado en 2004

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

scientific article published on 26 May 2020

Cyclin E2 induces genomic instability by mechanisms distinct from cyclin E1.

artículo científico publicado en 2013

Cyclin-dependent kinase 2 functions in normal DNA repair and is a therapeutic target in BRCA1-deficient cancers

artículo científico publicado en 2006

DNA interstrand crosslink repair and cancer ⬇️

artículo científico publicado el 24 de junio de 2011

Expression of a truncated Brca1 protein delays lactational mammary development in transgenic mice

article

FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex

artículo científico publicado en 2008

FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia

artículo científico publicado en 2009

FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops

artículo científico publicado en 2019

Fanconi proteins get histones moving.

artículo científico publicado en 2012

Granzyme A Deficiency Breaks Immune Tolerance and Promotes Autoimmune Diabetes Through a Type I Interferon-Dependent Pathway

artículo científico publicado en 2017

Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2

artículo científico publicado en 2010

MAD1 and p27(KIP1) cooperate to promote terminal differentiation of granulocytes and to inhibit Myc expression and cyclin E-CDK2 activity

artículo científico publicado en 2002

MMTV-trBrca1 mice display strain-dependent abnormalities in vaginal development

artículo científico publicado en 2004

Mechanism of Ubiquitination and Deubiquitination in the Fanconi Anemia Pathway

artículo científico publicado en 2016

Methodology for the identification of small molecule inhibitors of the Fanconi Anaemia ubiquitin E3 ligase complex

artículo científico publicado en 2020

Monoubiquitination by the human Fanconi Anemia core complex clamps FANCI:FANCD2 on DNA in filamentous arrays

artículo científico publicado en 2020

No evidence that CDKN1B (p27) polymorphisms modify breast cancer risk in BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2008

Phosphorylation of Drosophila Brahma on CDK-phosphorylation sites is important for cell cycle regulation and differentiation

artículo científico publicado en 2018

Preparation and purification of mono-ubiquitinated proteins using Avi-tagged ubiquitin

artículo científico publicado en 2020

Structural insight into FANCI-FANCD2 monoubiquitination

artículo científico publicado en 2020

The DNA translocase activity of FANCM protects stalled replication forks

artículo científico publicado en 2012

The FA Core Complex Contains a Homo-dimeric Catalytic Module for the Symmetric Mono-ubiquitination of FANCI-FANCD2.

artículo científico publicado en 2016

The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)

scientific article published on 28 May 2019

The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription

artículo científico publicado en 2015

The Fanconi anemia DNA repair pathway: structural and functional insights into a complex disorder

artículo científico publicado en 2014

The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair

artículo científico publicado en 2016

The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis

artículo científico publicado en 2014

The architecture and evolution of cancer neochromosomes

artículo científico publicado en 2014

Lista de obras de Andrew J Deans

A defined role for multiple Fanconi anemia gene products in DNA-damage-associated ubiquitination.

ALT control, delete: FANCM as an anti-cancer target in Alternative Lengthening of Telomeres

ASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress.

ATP-dependent helicase activity is dispensable for the physiological functions of Recql4

Architecture and DNA Recognition Elements of the Fanconi Anemia FANCM-FAAP24 Complex

Author Correction: The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)

BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage

Brca1 inactivation induces p27(Kip1)-dependent cell cycle arrest and delayed development in the mouse mammary gland.

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

Cyclin E2 induces genomic instability by mechanisms distinct from cyclin E1.

Cyclin-dependent kinase 2 functions in normal DNA repair and is a therapeutic target in BRCA1-deficient cancers

DNA interstrand crosslink repair and cancer ⬇️

Expression of a truncated Brca1 protein delays lactational mammary development in transgenic mice

FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex

FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia

FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops

Fanconi proteins get histones moving.

Granzyme A Deficiency Breaks Immune Tolerance and Promotes Autoimmune Diabetes Through a Type I Interferon-Dependent Pathway

Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2

MAD1 and p27(KIP1) cooperate to promote terminal differentiation of granulocytes and to inhibit Myc expression and cyclin E-CDK2 activity

MMTV-trBrca1 mice display strain-dependent abnormalities in vaginal development

Mechanism of Ubiquitination and Deubiquitination in the Fanconi Anemia Pathway

Methodology for the identification of small molecule inhibitors of the Fanconi Anaemia ubiquitin E3 ligase complex

Monoubiquitination by the human Fanconi Anemia core complex clamps FANCI:FANCD2 on DNA in filamentous arrays

No evidence that CDKN1B (p27) polymorphisms modify breast cancer risk in BRCA1 and BRCA2 mutation carriers

Phosphorylation of Drosophila Brahma on CDK-phosphorylation sites is important for cell cycle regulation and differentiation

Preparation and purification of mono-ubiquitinated proteins using Avi-tagged ubiquitin

Structural insight into FANCI-FANCD2 monoubiquitination

The DNA translocase activity of FANCM protects stalled replication forks

The FA Core Complex Contains a Homo-dimeric Catalytic Module for the Symmetric Mono-ubiquitination of FANCI-FANCD2.

The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)

The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription

The Fanconi anemia DNA repair pathway: structural and functional insights into a complex disorder

The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair

The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis

The architecture and evolution of cancer neochromosomes