Lista de obras - Jose L Rosa - Dominio Público Uruguay

6-Phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxia

artículo científico publicado en 2004

A new homozygous HERC1 gain-of-function variant in MDFPMR syndrome leads to mTORC1 hyperactivation and reduced autophagy during cell catabolism

artículo científico publicado en 2020

A nonsense variant in HERC1 is associated with intellectual disability, megalencephaly, thick corpus callosum and cerebellar atrophy

artículo científico publicado en 2015

ACVR1 Function in Health and Disease

scientific article published on 31 October 2019

Akt-dependent activation of the heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB2) isoenzyme by amino acids.

artículo científico publicado en 2013

Amino acids activate mammalian target of rapamycin complex 2 (mTORC2) via PI3K/Akt signaling

artículo científico publicado en 2010

Analysis of Protein Oligomerization by Electrophoresis

artículo científico publicado en 2016

Antiproliferative effect of catechin in GRX cells.

artículo científico publicado en 2012

BMP-2 decreases Mash1 stability by increasing Id1 expression

artículo científico publicado en 2004

Capsaicin modulates proliferation, migration, and activation of hepatic stellate cells.

artículo científico publicado en 2014

Class I PI-3-Kinase Signaling Is Critical for Bone Formation Through Regulation of SMAD1 Activity in Osteoblasts.

artículo científico publicado en 2016

Contribution of S6K1/MAPK signaling pathways in the response to oxidative stress: activation of RSK and MSK by hydrogen peroxide

artículo científico publicado en 2013

Correction: Contribution of S6K1/MAPK Signaling Pathways in the Response to Oxidative Stress: Activation of RSK and MSK by Hydrogen Peroxide

scholarly article published in PLOS ONE

Corrigendum to "ERK and p38 pathways regulate amino acid signalling" [BBA-Mol. Cell. Res. Volume 1783/12 (2008) 2241-2254]

scientific article published on 25 June 2019

Direct Binding of Smad1 and Smad4 to Two Distinct Motifs Mediates Bone Morphogenetic Protein-specific Transcriptional Activation ofId1 Gene ⬇️

artículo científico publicado el 7 de noviembre de 2001

ERK and p38 pathways regulate amino acid signalling

artículo científico publicado en 2008

Extracellular calcium promotes bone formation from bone marrow mesenchymal stem cells by amplifying the effects of BMP-2 on SMAD signalling

artículo científico publicado en 2017

Fructose-1,6-bisphosphate protects against Zymosan-induced acute lung injury in mice

artículo científico publicado en 2012

Fructose-1,6-bisphosphate reduces the mortality in Candida albicans bloodstream infection and prevents the septic-induced platelet decrease

artículo científico publicado en 2012

Functional EF-hands in neuronal calcium sensor GCAP2 determine its phosphorylation state and subcellular distribution in vivo, and are essential for photoreceptor cell integrity

artículo científico publicado en 2014

Functional and pathological relevance of HERC family proteins: a decade later.

artículo científico publicado en 2016

Glucose Restriction Promotes Osteocyte Specification by Activating a PGC-1α-Dependent Transcriptional Program

artículo científico publicado en 2019

Guaraná, a Highly Caffeinated Food, Presents in vitro Antitumor Activity in Colorectal and Breast Cancer Cell Lines by Inhibiting AKT/mTOR/S6K and MAPKs Pathways

artículo científico publicado en 2017

HERC 1 Ubiquitin Ligase Mutation Affects Neocortical, CA3 Hippocampal and Spinal Cord Projection Neurons: An Ultrastructural Study.

artículo científico publicado en 2016

HERC Ubiquitin Ligases in Cancer

artículo científico publicado en 2020

HERC1 Ubiquitin Ligase Is Required for Hippocampal Learning and Memory

artículo científico publicado en 2020

HERC1 Ubiquitin Ligase Is Required for Normal Axonal Myelination in the Peripheral Nervous System.

artículo científico publicado en 2018

HERCing: Structural and Functional Relevance of the Large HERC Ubiquitin Ligases

scientific article published on 07 August 2019

Inhibition of PI3K/p70 S6K and p38 MAPK cascades increases osteoblastic differentiation induced by BMP-2.

artículo científico publicado en 2002

Inhibition of phosphatidylinositol 3-kinase α (PI3Kα) prevents heterotopic ossification

artículo científico publicado en 2019

Interaction between HERC1 and M2-type pyruvate kinase

artículo científico publicado en 2003

Interplay between BMPs and Reactive Oxygen Species in Cell Signaling and Pathology

scientific article published on 26 September 2019

Large HERCs Function as Tumor Suppressors

scientific article published on 18 June 2019

Leucine reduces the proliferation of MC3T3-E1 cells through DNA damage and cell senescence.

artículo científico publicado en 2017

Liraglutide improves liver microvascular dysfunction in cirrhosis: Evidence from translational studies.

artículo científico publicado en 2017

Mesenchymal Stem Cells Within Gelatin/CaSO4 Scaffolds Treated Ex Vivo with Low Doses of BMP-2 and Wnt3a Increase Bone Regeneration

artículo científico publicado en 2015

Mesenchymal stem cells decrease lung inflammation during sepsis, acting through inhibition of the MAPK pathway.

artículo científico publicado en 2017

Mesenchymal stem cells improves survival in LPS-induced acute lung injury acting through inhibition of NETs formation.

artículo científico publicado en 2017

Mitogen-activated protein kinase (MAPK)-regulated interactions between Osterix and Runx2 are critical for the transcriptional osteogenic program

artículo científico publicado en 2014

Mutation of HERC2 causes developmental delay with Angelman-like features.

artículo científico publicado en 2012

NEURL4 regulates the transcriptional activity of tumor suppressor protein p53 by modulating its oligomerization.

artículo científico publicado en 2017

NRF2 function in osteocytes is required for bone homeostasis and drives osteocytic gene expression

artículo científico publicado en 2020

PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli

artículo científico publicado en 2013

Pfkfb3 is transcriptionally upregulated in diabetic mouse liver through proliferative signals.

artículo científico publicado en 2009

Post-translational regulation of retinal IMPDH1 in vivo to adjust GTP synthesis to illumination conditions

scientific article published on 07 April 2020

Progestins activate 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) in breast cancer cells

artículo científico publicado en 2012

Progressive Purkinje cell degeneration in tambaleante mutant mice is a consequence of a missense mutation in HERC1 E3 ubiquitin ligase

artículo científico publicado en 2009

Regulation of the MDM2-p53 pathway by the ubiquitin ligase HERC2

scientific article published on 15 November 2019

Regulation of ubiquitous 6-phosphofructo-2-kinase by the ubiquitin-proteasome proteolytic pathway during myogenic C2C12 cell differentiation

artículo científico publicado en 2003

Requirement of phosphatidylinositol-4,5-bisphosphate for HERC1-mediated guanine nucleotide release from ARF proteins

artículo científico publicado en 2005

Sertoli-secreted FGF-2 induces PFKFB4 isozyme expression in mouse spermatogenic cells by activation of the MEK/ERK/CREB pathway.

artículo científico publicado en 2012

Simultaneous electrophoretic analysis of proteins of very high and low molecular mass using Tris-acetate polyacrylamide gels.

artículo científico publicado en 2010

Simultaneous electrophoretic analysis of proteins of very high and low molecular weights using low-percentage acrylamide gel and a gradient SDS-PAGE gel.

artículo científico publicado en 2006

TGF-β1 targets Smad, p38 MAPK, and PI3K/Akt signaling pathways to induce PFKFB3 gene expression and glycolysis in glioblastoma cells

artículo científico publicado en 2017

TSC1 stabilizes TSC2 by inhibiting the interaction between TSC2 and the HERC1 ubiquitin ligase.

artículo científico publicado en 2006

The E3 ubiquitin ligase HERC1 controls the ERK signaling pathway targeting C-RAF for degradation

scientific article published on 31 July 2018

The E3 ubiquitin protein ligase HERC2 modulates the activity of tumor protein p53 by regulating its oligomerization

artículo científico publicado en 2014

The HERC1 ubiquitin ligase regulates presynaptic membrane dynamics of central synapses

artículo científico publicado en 2020

The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination.

artículo científico publicado en 2016

The RCC1 superfamily: from genes, to function, to disease.

artículo científico publicado en 2008

The combination of sirolimus and rosiglitazone produces a renoprotective effect on diabetic kidney disease in rats

artículo científico publicado en 2010

The giant protein HERC1 is recruited to aluminum fluoride-induced actin-rich surface protrusions in HeLa cells.

artículo científico publicado en 2004

The transcriptional activation of the cyclooxygenase-2 gene in zymosan-activated macrophages is dependent on NF-kappa B, C/EBP, AP-1, and CRE sites

artículo científico publicado en 2011

The ubiquitin ligase HERC1 regulates cell migration via RAF-dependent regulation of MKK3/p38 signaling

artículo científico publicado en 2020

Therapeutic ultrasound stimulates MC3T3-E1 cell proliferation through the activation of NF-κB1, p38α, and mTOR.

artículo científico publicado en 2015

Treatment with N-methyl-D-aspartate receptor antagonist (MK-801) protects against oxidative stress in lipopolysaccharide-induced acute lung injury in the rat.

artículo científico publicado en 2011

Tris-Acetate Polyacrylamide Gradient Gels for the Simultaneous Electrophoretic Analysis of Proteins of Very High and Low Molecular Mass

scientific article published on 01 January 2019

Tris-acetate polyacrylamide gradient gel electrophoresis for the analysis of protein oligomerization.

artículo científico publicado en 2016

Tris-acetate polyacrylamide gradient gels for the simultaneous electrophoretic analysis of proteins of very high and low molecular mass

artículo científico publicado en 2012

p53 inhibits SP7/Osterix activity in the transcriptional program of osteoblast differentiation

artículo científico

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Lista de obras de Jose L Rosa

6-Phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxia

A new homozygous HERC1 gain-of-function variant in MDFPMR syndrome leads to mTORC1 hyperactivation and reduced autophagy during cell catabolism

A nonsense variant in HERC1 is associated with intellectual disability, megalencephaly, thick corpus callosum and cerebellar atrophy

ACVR1 Function in Health and Disease

Akt-dependent activation of the heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB2) isoenzyme by amino acids.

Amino acids activate mammalian target of rapamycin complex 2 (mTORC2) via PI3K/Akt signaling

Analysis of Protein Oligomerization by Electrophoresis

Antiproliferative effect of catechin in GRX cells.

BMP-2 decreases Mash1 stability by increasing Id1 expression

Capsaicin modulates proliferation, migration, and activation of hepatic stellate cells.

Class I PI-3-Kinase Signaling Is Critical for Bone Formation Through Regulation of SMAD1 Activity in Osteoblasts.

Contribution of S6K1/MAPK signaling pathways in the response to oxidative stress: activation of RSK and MSK by hydrogen peroxide

Correction: Contribution of S6K1/MAPK Signaling Pathways in the Response to Oxidative Stress: Activation of RSK and MSK by Hydrogen Peroxide

Corrigendum to "ERK and p38 pathways regulate amino acid signalling" [BBA-Mol. Cell. Res. Volume 1783/12 (2008) 2241-2254]

Direct Binding of Smad1 and Smad4 to Two Distinct Motifs Mediates Bone Morphogenetic Protein-specific Transcriptional Activation ofId1 Gene ⬇️

ERK and p38 pathways regulate amino acid signalling

Extracellular calcium promotes bone formation from bone marrow mesenchymal stem cells by amplifying the effects of BMP-2 on SMAD signalling

Fructose-1,6-bisphosphate protects against Zymosan-induced acute lung injury in mice

Fructose-1,6-bisphosphate reduces the mortality in Candida albicans bloodstream infection and prevents the septic-induced platelet decrease

Functional EF-hands in neuronal calcium sensor GCAP2 determine its phosphorylation state and subcellular distribution in vivo, and are essential for photoreceptor cell integrity

Functional and pathological relevance of HERC family proteins: a decade later.

Glucose Restriction Promotes Osteocyte Specification by Activating a PGC-1α-Dependent Transcriptional Program

Guaraná, a Highly Caffeinated Food, Presents in vitro Antitumor Activity in Colorectal and Breast Cancer Cell Lines by Inhibiting AKT/mTOR/S6K and MAPKs Pathways

HERC 1 Ubiquitin Ligase Mutation Affects Neocortical, CA3 Hippocampal and Spinal Cord Projection Neurons: An Ultrastructural Study.

HERC Ubiquitin Ligases in Cancer

HERC1 Ubiquitin Ligase Is Required for Hippocampal Learning and Memory

HERC1 Ubiquitin Ligase Is Required for Normal Axonal Myelination in the Peripheral Nervous System.

HERCing: Structural and Functional Relevance of the Large HERC Ubiquitin Ligases

Inhibition of PI3K/p70 S6K and p38 MAPK cascades increases osteoblastic differentiation induced by BMP-2.

Inhibition of phosphatidylinositol 3-kinase α (PI3Kα) prevents heterotopic ossification

Interaction between HERC1 and M2-type pyruvate kinase

Interplay between BMPs and Reactive Oxygen Species in Cell Signaling and Pathology

Large HERCs Function as Tumor Suppressors

Leucine reduces the proliferation of MC3T3-E1 cells through DNA damage and cell senescence.

Liraglutide improves liver microvascular dysfunction in cirrhosis: Evidence from translational studies.

Mesenchymal Stem Cells Within Gelatin/CaSO4 Scaffolds Treated Ex Vivo with Low Doses of BMP-2 and Wnt3a Increase Bone Regeneration

Mesenchymal stem cells decrease lung inflammation during sepsis, acting through inhibition of the MAPK pathway.

Mesenchymal stem cells improves survival in LPS-induced acute lung injury acting through inhibition of NETs formation.

Mitogen-activated protein kinase (MAPK)-regulated interactions between Osterix and Runx2 are critical for the transcriptional osteogenic program

Mutation of HERC2 causes developmental delay with Angelman-like features.

NEURL4 regulates the transcriptional activity of tumor suppressor protein p53 by modulating its oligomerization.

NRF2 function in osteocytes is required for bone homeostasis and drives osteocytic gene expression

PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli

Pfkfb3 is transcriptionally upregulated in diabetic mouse liver through proliferative signals.

Post-translational regulation of retinal IMPDH1 in vivo to adjust GTP synthesis to illumination conditions

Progestins activate 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) in breast cancer cells

Progressive Purkinje cell degeneration in tambaleante mutant mice is a consequence of a missense mutation in HERC1 E3 ubiquitin ligase

Regulation of the MDM2-p53 pathway by the ubiquitin ligase HERC2

Regulation of ubiquitous 6-phosphofructo-2-kinase by the ubiquitin-proteasome proteolytic pathway during myogenic C2C12 cell differentiation

Requirement of phosphatidylinositol-4,5-bisphosphate for HERC1-mediated guanine nucleotide release from ARF proteins

Sertoli-secreted FGF-2 induces PFKFB4 isozyme expression in mouse spermatogenic cells by activation of the MEK/ERK/CREB pathway.

Simultaneous electrophoretic analysis of proteins of very high and low molecular mass using Tris-acetate polyacrylamide gels.

Simultaneous electrophoretic analysis of proteins of very high and low molecular weights using low-percentage acrylamide gel and a gradient SDS-PAGE gel.

TGF-β1 targets Smad, p38 MAPK, and PI3K/Akt signaling pathways to induce PFKFB3 gene expression and glycolysis in glioblastoma cells

TSC1 stabilizes TSC2 by inhibiting the interaction between TSC2 and the HERC1 ubiquitin ligase.

The E3 ubiquitin ligase HERC1 controls the ERK signaling pathway targeting C-RAF for degradation

The E3 ubiquitin protein ligase HERC2 modulates the activity of tumor protein p53 by regulating its oligomerization

The HERC1 ubiquitin ligase regulates presynaptic membrane dynamics of central synapses

The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination.

The RCC1 superfamily: from genes, to function, to disease.

The combination of sirolimus and rosiglitazone produces a renoprotective effect on diabetic kidney disease in rats

The giant protein HERC1 is recruited to aluminum fluoride-induced actin-rich surface protrusions in HeLa cells.

The transcriptional activation of the cyclooxygenase-2 gene in zymosan-activated macrophages is dependent on NF-kappa B, C/EBP, AP-1, and CRE sites

The ubiquitin ligase HERC1 regulates cell migration via RAF-dependent regulation of MKK3/p38 signaling

Therapeutic ultrasound stimulates MC3T3-E1 cell proliferation through the activation of NF-κB1, p38α, and mTOR.

Treatment with N-methyl-D-aspartate receptor antagonist (MK-801) protects against oxidative stress in lipopolysaccharide-induced acute lung injury in the rat.

Tris-Acetate Polyacrylamide Gradient Gels for the Simultaneous Electrophoretic Analysis of Proteins of Very High and Low Molecular Mass

Tris-acetate polyacrylamide gradient gel electrophoresis for the analysis of protein oligomerization.

Tris-acetate polyacrylamide gradient gels for the simultaneous electrophoretic analysis of proteins of very high and low molecular mass

p53 inhibits SP7/Osterix activity in the transcriptional program of osteoblast differentiation

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)