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Lista de obras de Joel M Guthridge

A comprehensive and universal method for assessing the performance of differential gene expression analyses

artículo científico publicado en 2010

A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus

artículo científico publicado en 2012

A nonsynonymous functional variant in integrin-αM (encoded by ITGAM) is associated with systemic lupus erythematosus

article

A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus

scholarly article by Zubin Patel published in April 2018

ABIN1 dysfunction as a genetic basis for lupus nephritis

artículo científico publicado en 2013

Aberrant Epstein-Barr viral infection in systemic lupus erythematosus

artículo científico publicado en 2009

Activation-Dependent Apoptosis in CD4+ T Cells during Murine AIDS

article

Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production

artículo científico publicado en 2013

Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations

artículo científico publicado en 2013

Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification

artículo científico publicado en 2016

Antibodies to periodontogenic bacteria are associated with higher disease activity in lupus patients

artículo científico publicado en 2018

Association of IFIH1 and pro-inflammatory mediators: Potential new clues in SLE-associated pathogenesis

artículo científico publicado en 2017

Association of a functional IRF7 variant with systemic lupus erythematosus

artículo científico publicado en 2011

Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus

artículo científico publicado en 2011

Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility

artículo científico publicado en 2011

Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus

artículo científico publicado en 2012

Author Correction: Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways

scientific article published on 01 November 2019

Autoantibodies against Neurologic Antigens in Nonneurologic Autoimmunity

artículo científico publicado en 2019

Autoantibody-Positive Healthy Individuals Display Unique Immune Profiles That May Regulate Autoimmunity

artículo científico publicado en 2016

B lymphocyte stimulator levels in systemic lupus erythematosus: higher circulating levels in African American patients and increased production after influenza vaccination in patients with low baseline levels

artículo científico publicado en 2011

B-Cell and Monocyte Contribution to Systemic Lupus Erythematosus Identified by Cell-Type-Specific Differential Expression Analysis in RNA-Seq Data

artículo científico publicado en 2015

Brief Report: Patients With Primary Sjögren's Syndrome Who Are Positive for Autoantibodies to Tripartite Motif-Containing Protein 38 Show Greater Disease Severity

artículo científico publicado en 2015

CR2-C3D COMPLEX STRUCTURE

Characterization of a complement receptor 2 (CR2, CD21) ligand binding site for C3. An initial model of ligand interaction with two linked short consensus repeat modules

artículo científico publicado en 1995

Characterization of a low molecular weight isoform of IL-1 receptor antagonist

artículo científico publicado el 15 de agosto de 1998

Clinical and serological features distinguish patients with incomplete lupus classification from systemic lupus erythematosus patients and controls

artículo científico publicado en 2017

Combined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus

artículo científico publicado en 2016

Comparison of autoantibody specificities between traditional and bead-based assays in a large, diverse collection of patients with systemic lupus erythematosus and family members

artículo científico publicado en 2012

Complement C3 activation is required for antiphospholipid antibody-induced fetal loss

artículo científico publicado en 2002

Complement inhibitor, complement receptor 1-related gene/protein y-Ig attenuates intestinal damage after the onset of mesenteric ischemia/reperfusion injury in mice

scientific journal article

Complement is activated in kidney by endotoxin but does not cause the ensuing acute renal failure

scientific article published on 01 October 2000

Complement receptor 2-mediated targeting of complement inhibitors to sites of complement activation

artículo científico publicado en 2003

Complement receptor 2–mediated targeting of complement inhibitors to sites of complement activation

Complement receptor chimaeric conjugate CR2-Ig

Crry-IG, an inhibitor of C3 activation, blocks anti-phospholipid AB (aPL) induced fetal loss

Crry-Ig, a complement activation inhibitor, protects mice from ischemia /reperfusion (IR) induced intestinal injury

Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.

artículo científico publicado en 2013

Discerning Risk of Disease Transition in Relatives of Systemic Lupus Erythematosus Patients Utilizing Soluble Mediators and Clinical Features.

artículo científico publicado en 2016

Dysregulation of innate and adaptive serum mediators precedes systemic lupus erythematosus classification and improves prognostic accuracy of autoantibodies

artículo científico publicado en 2016

Early targets of nuclear RNP humoral autoimmunity in human systemic lupus erythematosus

artículo científico publicado en 2009

Effects of IRF5 lupus risk haplotype on pathways predicted to influence B cell functions

artículo científico publicado en 2012

Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks

scientific article published in Nature Communications

Epitope Mapping Using the X-Ray Crystallographic Structure of Complement Receptor Type 2 (CR2)/CD21: Identification of a Highly Inhibitory Monoclonal Antibody That Directly Recognizes the CR2-C3d Interface

scientific article published on 01 November 2001

Epstein Barr Virus Interleukin 10 Suppresses Anti-inflammatory Phenotype in Human Monocytes

Erratum: Genetic associations of LYN with systemic lupus erythematosus

article

Erratum: Systemic lupus erythematosus (SLE) and chromosome 16: confirmation of linkage to 16q12–13 and evidence for genetic heterogeneity

scholarly article by Swapan K Nath et al published 22 July 2004 in European Journal of Human Genetics

Ethical and practical issues associated with aggregating databases

artículo científico publicado en 2008

Evaluation of 19 autoimmune disease-associated loci with rheumatoid arthritis in a Colombian population: evidence for replication and gene-gene interaction

artículo científico publicado en 2011

Evaluation of TRAF6 in a large multiancestral lupus cohort

artículo científico publicado en 2012

Evaluation of imputation-based association in and around the integrin-alpha-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE).

artículo científico publicado en 2009

Evidence of dynamically dysregulated gene expression pathways in hyperresponsive B cells from African American lupus patients

artículo científico publicado en 2013

Expression and methylation data from SLE patient and healthy control blood samples subdivided with respect to ARID3a levels

artículo científico publicado en 2016

Extended flexible linker structures in the complement chimaeric conjugate CR2-Ig by scattering, analytical ultracentrifugation and constrained modelling: implications for function and therapy

artículo científico publicado en 2005

Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups

artículo científico publicado en 2012

Fine specificity mapping of autoantigens targeted by anti-centromere autoantibodies

artículo científico publicado en 2006

Functional characterization of the MECP2/IRAK1 lupus risk haplotype in human T cells and a human MECP2 transgenic mouse

artículo científico publicado en 2013

Gamma-glutamyl transpeptidase, an ecto-enzyme regulator of intracellular redox potential, is a component of TM4 signal transduction complexes

artículo científico publicado en 1998

Generation of novel C3dg tetramers for the analysis of CD21 binding and function

Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK.

artículo científico publicado en 2011

Genetic association of CD247 (CD3ζ) with SLE in a large-scale multiethnic study.

artículo científico publicado en 2015

Genetic associations of LYN with systemic lupus erythematosus

artículo científico publicado en 2009

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

artículo científico publicado en 2008

Herpes zoster vaccination in SLE: a pilot study of immunogenicity

artículo científico publicado en 2013

High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups

artículo científico publicado en 2009

Human effector B lymphocytes express ARID3a and secrete interferon alpha

artículo científico publicado en 2016

Human monoclonal antibodies generated following vaccination with AVA provide neutralization by blocking furin cleavage but not by preventing oligomerization

artículo científico publicado el 14 de marzo de 2012

IFN-β treatment requires B cells for efficacy in neuroautoimmunity.

artículo científico publicado en 2015

ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash and immunological manifestations in patients with systemic lupus erythematosus with European ancestry

artículo científico publicado en 2009

Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study

artículo científico publicado en 2012

Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons

artículo científico publicado en 2017

Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study

artículo científico publicado en 2010

Identification of multiple genetic susceptibility loci in Takayasu arteritis

artículo científico publicado en 2013

Identification of unique microRNA signature associated with lupus nephritis

artículo científico publicado en 2010

Immunologic findings precede rapid lupus flare after transient steroid therapy

artículo científico publicado en 2019

Influenza vaccination can induce new-onset anticardiolipins but not β2-glycoprotein-I antibodies among patients with systemic lupus erythematosus

artículo científico publicado en 2012

Influenza vaccination responses in human systemic lupus erythematosus: impact of clinical and demographic features

artículo científico publicado en 2011

Inhibiting the complement system does not reduce injury in renal ischemia reperfusion

artículo científico publicado en 2001

Inhibition of ischemia reperfusion-induced intestinal injury and systemic inflammation by a novel complement regulatory protein

Interaction of calcium and Ro60: increase of antigenicity

artículo científico publicado en 2004

Internal standard-based analysis of microarray data2--analysis of functional associations between HVE-genes

artículo científico publicado en 2011

Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients

Less than 7 hours of sleep per night is associated with transitioning to systemic lupus erythematosus

article by K A Young et al published August 2018 in Lupus

Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression

artículo científico publicado en 2015

Lupus risk variants in the PXK locus alter B-cell receptor internalization

artículo científico publicado en 2014

Mice Deficient in Complement Receptors 1 and 2 Lack a Tissue Injury-Inducing Subset of the Natural Antibody Repertoire

scientific article published on 01 August 2002

Model of mouse Crry-Ig determined by solution scattering, curve fitting and homology modelling

scholarly article published 3 February 2004

Model of rat Crry determined by solution scattering, curve fitting and homology modelling

scholarly article published 3 February 2004

Multiple Autoantibodies Display Association with Lymphopenia, Proteinuria, and Cellular Casts in a Large, Ethnically Diverse SLE Patient Cohort

artículo científico publicado en 2012

Mutational analysis of the complement receptor type 2 (CR2/CD21)-C3d interaction reveals a putative charged SCR1 binding site for C3d.

artículo científico publicado en 2005

Mycophenolate mofetil reduces STAT3 phosphorylation in systemic lupus erythematosus patients

scholarly article by Samantha Slight-Webb et al published 24 January 2019 in JCI insight

Novel inhibitory monoclonal antibodies to human CR2/CD21 ligand binding domains

Osteopontin and systemic lupus erythematosus association: a probable gene-gender interaction

artículo científico publicado en 2008

Overlapping B cell pathways in severe COVID-19 and lupus

artículo científico publicado en 2020

PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21

scientific article published on 17 October 2019

PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes

artículo científico publicado en 2013

Pathways of impending disease flare in African-American systemic lupus erythematosus patients

artículo científico publicado en 2017

Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA.

artículo científico publicado en 2014

Proinflammatory adaptive cytokine and shed tumor necrosis factor receptor levels are elevated preceding systemic lupus erythematosus disease flare

artículo científico publicado en 2014

Regulation of B cell:T cell interactions: potential involvement of an endogenous B cell sialidase

artículo científico publicado en 1994

Replication of the BANK1 genetic association with systemic lupus erythematosus in a European-derived population

scientific article published on 02 April 2009

Role of CR2- and CD19-regulated natural antibodies in intestinal ischemia reperfusion-induced injury

Role of MYH9 and APOL1 in African and non-African populations with lupus nephritis

artículo científico publicado en 2011

SLE patients and autoantibody-positive healthy individuals display unique cytokine profiles: shared features of inflammation as well as select features of immunosuppression in autoantibody-positive healthy individuals.

artículo científico publicado en 2012

Sa.54. Positional Identification of Integrin- αMβ2 (ITGAM) as a Susceptibility Gene for Systematic Lupus Erythematosus (SLE)

article

Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus

artículo científico publicado en 2010

Site-1 protease deficiency causes human skeletal dysplasia due to defective inter-organelle protein trafficking

artículo científico publicado en 2018

Smoking is not associated with autoantibody production in systemic lupus erythematosus patients, unaffected first-degree relatives, nor healthy controls

artículo científico publicado en 2014

Strong viral associations with SLE among Filipinos

artículo científico publicado en 2017

Structural analysis of recombinant human CD21 ligand binding domains

Structural studies in solution of the recombinant N-terminal pair of short consensus/complement repeat domains of complement receptor type 2 (CR2/CD21) and interactions with its ligand C3dg

artículo científico publicado en 2001

Systemic lupus erythematosus (SLE) and chromosome 16: confirmation of linkage to 16q12–13 and evidence for genetic heterogeneity

article

The Biomarkers of Lupus Disease Study: A Bold Approach May Mitigate Interference of Background Immunosuppressants in Clinical Trials

artículo científico publicado en 2017

The Clinical Efficacy and Safety of Baminercept, a Lymphotoxin-β Receptor Fusion Protein, in Primary Sjögren's Syndrome: Results from a Randomized, Double-Blind, Placebo-Controlled Phase II Trial

artículo científico publicado en 2018

The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share

artículo científico publicado en 2014

The Transcription Factor ARID3a Is Important for In Vitro Differentiation of Human Hematopoietic Progenitors

artículo científico

The curiously suspicious: a role for Epstein-Barr virus in lupus

artículo científico publicado en 2006

The effect of inversion at 8p23 on BLK association with lupus in Caucasian population

artículo científico publicado en 2014

The extended multidomain solution structures of the complement protein Crry and its chimeric conjugate Crry-Ig by scattering, analytical ultracentrifugation and constrained modelling: implications for function and therapy

artículo científico publicado en 2003

The role of genetic variation near interferon-kappa in systemic lupus erythematosus

artículo científico publicado en 2010

Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4.

artículo científico publicado en 2013

Transancestral mapping and genetic load in systemic lupus erythematosus

artículo científico

Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways

artículo científico publicado en 2019

Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription

artículo científico publicado en 2014

Unique Sjögren's syndrome patient subsets defined by molecular features

scientific article published on 01 April 2020

Unique clinical characteristics, autoantibodies and medication use in Native American patients with systemic lupus erythematosus

artículo científico publicado en 2018

Use of SLICC criteria in a large, diverse lupus registry enables SLE classification of a subset of ACR-designated subjects with incomplete lupus

scientific article published on 17 March 2017

Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry

artículo científico publicado en 2013

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome

artículo científico publicado en 2013

Variation in the ICAM1-ICAM4-ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries

artículo científico publicado en 2012

Vitamin D deficiency is associated with an increased autoimmune response in healthy individuals and in patients with systemic lupus erythematosus

artículo científico publicado en 2011

Vitamin d deficiency in a multiethnic healthy control cohort and altered immune response in vitamin D deficient European-American healthy controls

artículo científico publicado en 2014

X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome

artículo científico publicado en 2015