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Lista de obras de Saskia N de Wildt

A Comparative Analysis of Preemptive Versus Targeted Sedation on Cardiovascular Stability After High-Risk Cardiac Surgery in Infants

artículo científico publicado en 2016

A Population Pharmacokinetic Model to Predict the Individual Starting Dose of Tacrolimus Following Pediatric Renal Transplantation

artículo científico publicado en 2018

A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age‐dependent differences in absorption

artículo científico publicado en 2022

A systematic review of the therapeutic effects of Reiki

artículo científico publicado en 2009

Acute liver failure after recommended doses of acetaminophen in patients with myopathies

artículo científico publicado en 2011

Advanced cancer pain: the search for genetic factors correlated with interindividual variability in opioid requirement

artículo científico publicado en 2017

Analgesia-sedation in PICU and neurological outcome: a secondary analysis of long-term neuropsychological follow-up in meningococcal septic shock survivors*.

artículo científico publicado en 2014

CYP2D6 polymorphisms and codeine analgesia in postpartum pain management: a pilot study.

artículo científico publicado en 2011

Challenges for drug studies in children: CYP3A phenotyping as example

artículo científico publicado en 2008

Characterization of Intestinal and Hepatic CYP3A-Mediated Metabolism of Midazolam in Children Using a Physiological Population Pharmacokinetic Modelling Approach

artículo científico publicado en 2018

Clinically effective implementation of intravenous paracetamol as primary analgesia after major surgery in neonates and young infants

artículo científico publicado en 2018

Clonidine as a First-Line Sedative Agent After Neonatal Cardiac Surgery: Retrospective Cohort Study.

artículo científico publicado en 2016

Combining Brain Microdialysis and Translational Pharmacokinetic Modeling to Predict Drug Concentrations in Pediatric Severe Traumatic Brain Injury: The Next Step Toward Evidence-Based Pharmacotherapy?

scientific article published on 06 September 2018

Critical illness is a major determinant of midazolam clearance in children aged 1 month to 17 years

artículo científico publicado en 2012

Developing a paediatric drug formulary for the Netherlands.

artículo científico publicado en 2016

Development of Human Membrane Transporters: Drug Disposition and Pharmacogenetics

artículo científico publicado en 2016

Development of a physiologically-based pharmacokinetic pediatric brain model for prediction of cerebrospinal fluid drug concentrations and the influence of meningitis

artículo científico publicado en 2019

Developmental patterns in human blood-brain barrier and blood-cerebrospinal fluid barrier ABC drug transporter expression

scientific article published on 24 May 2020

Diagnosis and Treatment of Chronic Neuropathic and Mixed Pain in Children and Adolescents: Results of a Survey Study amongst Practitioners

artículo científico publicado en 2020

Differences in P-glycoprotein activity in human and rodent blood-brain barrier assessed by mechanistic modelling

artículo científico publicado en 2021

Disease-Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of Drugs: A White Paper From the International Transporter Consortium

artículo científico publicado en 2018

Dose-linearity of the pharmacokinetics of an intravenous [14 C]midazolam microdose in children

scientific article published on 30 July 2019

Effects of renal denervation on cardiovascular and renal responses to ACE inhibition in conscious lambs ⬇️

artículo científico publicado el 1 de agosto de 1997

Ethics of drug research in the pediatric intensive care unit

artículo científico publicado en 2015

Evaluation of drug formularies for pediatric intensive care

artículo científico publicado en 2011

Evidence-based morphine dosing for postoperative neonates and infants

artículo científico publicado en 2014

External Validation of Model-Based Dosing Guidelines for Vancomycin, Gentamicin, and Tobramycin in Critically Ill Neonates and Children: A Pragmatic Two-Center Study

artículo científico publicado en 2020

First-Pass CYP3A-Mediated Metabolism of Midazolam in the Gut Wall and Liver in Preterm Neonates.

artículo científico publicado en 2018

Genetic variants associated with thermal pain sensitivity in a paediatric population.

artículo científico publicado en 2016

Hemodynamic Tolerance to IV Clonidine Infusion in the PICU

artículo científico publicado en 2018

Human Intestinal PEPT1 Transporter Expression and Localization in Preterm and Term Infants

artículo científico publicado en 2016

Inflammation and Organ Failure Severely Affect Midazolam Clearance in Critically Ill Children

artículo científico publicado en 2016

Intoxication of a Young Girl Reveals the Pitfalls of GHB Rapid Screening.

artículo científico publicado en 2015

Knowledge of developmental pharmacology and modeling approaches should be used to avoid useless trials in children

artículo científico publicado en 2009

Low Bioavailability of Oral Tacrolimus Suspension in Pediatric Kidney Transplant Patients

artículo científico publicado en 2020

Macrolide prescription in Dutch children: compliance with guidelines

artículo científico publicado en 2019

Microdosing and Other Phase 0 Clinical Trials: Facilitating Translation in Drug Development.

artículo científico publicado en 2016

Non-inferiority double-blind randomised controlled trial comparing gabapentin versus tramadol for the treatment of chronic neuropathic or mixed pain in children and adolescents: the GABA-1 trial-a study protocol

artículo científico publicado en 2019

Ontogeny of midazolam glucuronidation in preterm infants

artículo científico publicado en 2009

Optimal sedation in pediatric intensive care patients: a systematic review

artículo científico

Oral lorazepam can be substituted for intravenous midazolam when weaning paediatric intensive care patients off sedation

artículo científico publicado en 2018

Pediatric microdose study of [(14)C]paracetamol to study drug metabolism using accelerated mass spectrometry: proof of concept

artículo científico publicado en 2014

Perspectives of adolescents on decision making about participation in a biobank study: a pilot study

artículo científico publicado en 2017

Pharmacokinetic studies in children: recommendations for practice and research.

artículo científico publicado en 2018

Pharmacology and pharmacogenetics of prednisone and prednisolone in patients with nephrotic syndrome.

artículo científico publicado en 2018

Pharmacotherapeutic management of paediatric heart failure and ACE-I use patterns: a European survey

artículo científico publicado en 2019

Population pharmacokinetics and metabolism of midazolam in pediatric intensive care patients.

artículo científico publicado en 2003

Population pharmacokinetics of intravenous clonidine for sedation during paediatric extracorporeal membrane oxygenation and continuous venovenous hemofiltration.

artículo científico publicado en 2017

Predicting CYP3A-mediated midazolam metabolism in critically ill neonates, infants, children and adults with inflammation and organ failure.

artículo científico publicado en 2017

Prevention of Low Cardiac Output Syndrome in children: where is the evidence?

article

Proenkephalin as a new biomarker for pediatric acute kidney injury - reference values and performance in children under one year of age

artículo científico publicado en 2020

Profound changes in drug metabolism enzymes and possible effects on drug therapy in neonates and children ⬇️

artículo científico publicado el 8 de mayo de 2011

Propylene Glycol–Related Delirium After Esmolol Infusion

artículo científico publicado en 2014

Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life

artículo científico publicado en 2016

Proteomics of human liver membrane transporters: a focus on fetuses and newborn infants

artículo científico publicado en 2018

Question 1: How safe are ACE inhibitors for heart failure in children?

artículo científico publicado en 2017

Rectal Omeprazole in Infants With Gastroesophageal Reflux Disease: A Randomized Pilot Trial

artículo científico publicado en 2020

Reference intervals for renal injury biomarkers neutrophil gelatinase-associated lipocalin and kidney injury molecule-1 in young infants

artículo científico publicado en 2015

Reply

Reply to Stamer, Ulrike; Stüber, Frank, regarding their comment 'Analgesic efficacy of dipyrone children - Still an absence of evidence'

scientific article published on 01 December 2018

Reply to Ziesenitz, Victoria; Erb Thomas; Trachsel, Daniel; van den Anker Johannes, regarding their comment "Safety of dipryone (metamizole) in children-what's the risk of agranulocytosis?"

artículo científico publicado en 2018

Roles of Clinical Research Networks in Pediatric Drug Development.

artículo científico publicado en 2017

SLC22A1/OCT1 Genotype Affects O-desmethyltramadol Exposure in Newborn Infants

artículo científico publicado en 2016

Sample collection, biobanking, and analysis

artículo científico

Short-Term Health-Related Quality of Life of Critically Ill Children Following Daily Sedation Interruption

artículo científico publicado en 2016

Striving for an effective but parsimonious use of sedation in pediatric intensive care.

artículo científico publicado en 2016

Successful Use of [14C]Paracetamol Microdosing to Elucidate Developmental Changes in Drug Metabolism

artículo científico publicado en 2017

Tailor-made drug treatment for children: creation of an infrastructure for data-sharing and population PK-PD modeling

artículo científico publicado en 2009

The Effect of Weight and CYP3A5 Genotype on the Population Pharmacokinetics of Tacrolimus in Stable Paediatric Renal Transplant Recipients

artículo científico publicado en 2016

The Ontogeny of UDP-glucuronosyltransferase Enzymes, Recommendations for Future Profiling Studies and Application Through Physiologically Based Pharmacokinetic Modelling

artículo científico publicado en 2019

The effect of critical illness and inflammation on midazolam therapy in children

artículo científico publicado en 2012

The interactions of age, genetics, and disease severity on tacrolimus dosing requirements after pediatric kidney and liver transplantation

artículo científico publicado en 2011

The potential impact of hematocrit correction on evaluation of tacrolimus target exposure in pediatric kidney transplant patients

scientific article published on 30 October 2018

The status of paediatric medicines initiatives around the world--What has happened and what has not?

scientific article published on 06 July 2011

The use of dipyrone (metamizol) as an analgesic in children: What is the evidence? A review.

artículo científico publicado en 2017

Unintended pregnancy during radiotherapy for cancer

artículo científico publicado en 2009

Urinary neutrophil gelatinase-associated lipocalin identifies critically ill young children with acute kidney injury following intensive care admission: a prospective cohort study

artículo científico publicado en 2015

Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the future.

artículo científico publicado en 2017

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