Lista de obras - Kate E. Lawlor - Dominio Público Uruguay

ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro

artículo científico publicado en 2005

Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner.

artículo científico publicado en 2017

Acute CD4+ T lymphocyte-dependent interleukin-1-driven arthritis selectively requires interleukin-2 and interleukin-4, joint macrophages, granulocyte-macrophage colony-stimulating factor, interleukin-6, and leukemia inhibitory factor

artículo científico publicado en 2005

Ambiguities in NLRP3 inflammasome regulation: is there a role for mitochondria?

artículo científico

Analysis of a wild mouse promoter variant reveals a novel role for FcγRIIb in the control of the germinal center and autoimmunity.

artículo científico publicado en 2012

Bcl-2 overexpression ameliorates immune complex-mediated arthritis by altering FcγRIIb expression and monocyte homeostasis

artículo científico publicado en 2013

Blocking aggrecanase cleavage in the aggrecan interglobular domain abrogates cartilage erosion and promotes cartilage repair

artículo científico publicado en 2007

CD52 inhibits Toll-like receptor activation of NF-κB and triggers apoptosis to suppress inflammation

artículo científico publicado en 2017

Caspase-8: not so silently deadly

scientific article published on 06 January 2017

Cell death is not essential for caspase-1-mediated interleukin-1β activation and secretion

artículo científico publicado en 2016

Critical role for granulocyte colony-stimulating factor in inflammatory arthritis

scholarly article

Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1β Secretion

artículo científico publicado en 2018

Die Another Way: Interplay between Influenza A Virus, Inflammation and Cell Death

scientific article published on 04 April 2020

Distinct cell-specific control of autoimmunity and infection by FcgammaRIIb

artículo científico publicado en 2008

Distinctive pro-inflammatory gene signatures induced in articular chondrocytes by oncostatin M and IL-6 are regulated by Suppressor of Cytokine Signaling-3.

artículo científico

Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis.

artículo científico publicado en 2016

Evaluation of the Bcl-2 family antagonist ABT-737 in collagen-induced arthritis

artículo científico publicado en 2011

FcγRIIb controls bone marrow plasma cell persistence and apoptosis

scientific article published on 18 February 2007

IAPs Regulate Distinct Innate Immune Pathways to Co-ordinate the Response to Bacterial Peptidoglycans

artículo científico publicado en 2018

IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome.

artículo científico publicado en 2015

Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation

artículo científico publicado en 2012

Key Role of Suppressor of Cytokine Signaling 3 in Regulating gp130 Cytokine-Induced Signaling and Limiting Chondrocyte Responses During Murine Inflammatory Arthritis

article

Loss of Bak enhances lymphocytosis but does not ameliorate thrombocytopaenia in BCL-2 transgenic mice.

artículo científico publicado en 2014

Matrix metalloproteinases are not essential for aggrecan turnover during normal skeletal growth and development

artículo científico publicado en 2005

Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming

artículo científico publicado en 2014

Mitochondrial dysfunction caused by outer membrane vesicles from Gram-negative bacteria activates intrinsic apoptosis and inflammation

artículo científico publicado en 2020

Molecular and cellular mediators of interleukin-1-dependent acute inflammatory arthritis

artículo científico publicado en 2001

More to life than death: molecular determinants of necroptotic and non-necroptotic RIP3 kinase signaling

artículo científico publicado en 2013

New insights into the regulation of innate immunity by caspase-8.

artículo científico publicado en 2016

Plasmacytoid dendritic cells are short-lived: reappraising the influence of migration, genetic factors and activation on estimation of lifespan

artículo científico publicado en 2016

Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation

artículo científico publicado en 2019

RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis

artículo científico publicado en 2014

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

artículo científico publicado en 2015

Suppressor of cytokine signaling-1 regulates acute inflammatory arthritis and T cell activation

artículo científico publicado en 2003

TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1.

artículo científico publicado en 2013

TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice.

artículo científico publicado en 2014

The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation

scientific article published on 01 November 2018

The pseudokinase MLKL activates PAD4-dependent NET formation in necroptotic neutrophils

scientific article published on 04 September 2018

The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradation

artículo científico publicado en 2021

Therapeutic Effects of a TANK-Binding Kinase 1 Inhibitor in Germinal Center-Driven Collagen-Induced Arthritis

artículo científico publicado en 2018

Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis.

artículo científico publicado en 2016

XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation.

artículo científico

cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner

scientific article published on 04 February 2014

Lista de obras de Kate E. Lawlor

ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro

Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner.

Acute CD4+ T lymphocyte-dependent interleukin-1-driven arthritis selectively requires interleukin-2 and interleukin-4, joint macrophages, granulocyte-macrophage colony-stimulating factor, interleukin-6, and leukemia inhibitory factor

Ambiguities in NLRP3 inflammasome regulation: is there a role for mitochondria?

Analysis of a wild mouse promoter variant reveals a novel role for FcγRIIb in the control of the germinal center and autoimmunity.

Bcl-2 overexpression ameliorates immune complex-mediated arthritis by altering FcγRIIb expression and monocyte homeostasis

Blocking aggrecanase cleavage in the aggrecan interglobular domain abrogates cartilage erosion and promotes cartilage repair

CD52 inhibits Toll-like receptor activation of NF-κB and triggers apoptosis to suppress inflammation

Caspase-8: not so silently deadly

Cell death is not essential for caspase-1-mediated interleukin-1β activation and secretion

Critical role for granulocyte colony-stimulating factor in inflammatory arthritis

Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1β Secretion

Die Another Way: Interplay between Influenza A Virus, Inflammation and Cell Death

Distinct cell-specific control of autoimmunity and infection by FcgammaRIIb

Distinctive pro-inflammatory gene signatures induced in articular chondrocytes by oncostatin M and IL-6 are regulated by Suppressor of Cytokine Signaling-3.

Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis.

Evaluation of the Bcl-2 family antagonist ABT-737 in collagen-induced arthritis

FcγRIIb controls bone marrow plasma cell persistence and apoptosis

IAPs Regulate Distinct Innate Immune Pathways to Co-ordinate the Response to Bacterial Peptidoglycans

IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome.

Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation

Key Role of Suppressor of Cytokine Signaling 3 in Regulating gp130 Cytokine-Induced Signaling and Limiting Chondrocyte Responses During Murine Inflammatory Arthritis

Loss of Bak enhances lymphocytosis but does not ameliorate thrombocytopaenia in BCL-2 transgenic mice.

Matrix metalloproteinases are not essential for aggrecan turnover during normal skeletal growth and development

Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming

Mitochondrial dysfunction caused by outer membrane vesicles from Gram-negative bacteria activates intrinsic apoptosis and inflammation

Molecular and cellular mediators of interleukin-1-dependent acute inflammatory arthritis

More to life than death: molecular determinants of necroptotic and non-necroptotic RIP3 kinase signaling

New insights into the regulation of innate immunity by caspase-8.

Plasmacytoid dendritic cells are short-lived: reappraising the influence of migration, genetic factors and activation on estimation of lifespan

Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation

RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

Suppressor of cytokine signaling-1 regulates acute inflammatory arthritis and T cell activation

TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1.

TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice.

The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation

The pseudokinase MLKL activates PAD4-dependent NET formation in necroptotic neutrophils

The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradation

Therapeutic Effects of a TANK-Binding Kinase 1 Inhibitor in Germinal Center-Driven Collagen-Induced Arthritis

Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis.

XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation.

cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner